M E Ernst

..Pharmacists should take an active role in providing education to this poorly served group to help reduce risks of medication misadventures...

..5-25 mg) remains more widely prescribed. We sought to describe their comparative dose-response relationships for changes in systolic blood pressure (SBP) and potassium...

..Selection of the proper diuretic agent and its dosing strategy are dependent on knowledge of within-class characteristics, as well as a commensurate understanding of the physiology of the disease being treated...

..Pharmacist-physician comanagement of hypertension has been shown to improve office blood pressures (BPs). We sought to describe the effect of such a model on 24-hour ambulatory BPs...

..This review summarizes recent evidence supporting the predictive ability of ambulatory blood pressure monitoring and briefly highlights opportunities for clinical pharmacists to adopt this important clinical and research tool...

..Objectives: To evaluate QOL in women treated for acute cystitis, and describe the relationship between QOL, clinical outcome and adverse events of each of the interventions used in the study...

..The objective of this study was to describe patient satisfaction with ABPM performed in a primary care office in the United States, using modern ABPM technology...

..To evaluate patient outcomes after 4 years of anticoagulation case management by a pharmacist and to document patient and provider satisfaction with the service...

..8+/-3.5; P=0.84). Within recommended doses, chlorthalidone is more effective in lowering systolic BPs than hydrochlorothiazide, as evidenced by 24-hour ambulatory BPs. These differences were not apparent with office BP measurements...

..However, shortened sessions do not characterize the influence of circadian variation on the 24-hour mean BP and may overestimate the 24-hour BP levels...

..371). No correlation was observed between atmospheric pressure changes and INR variability. These findings refute the anecdotal experience seen in our anticoagulation clinic...

..Objective: The purpose of this review was to summarize available information about the clinical use of febuxostat, including its chemistry, pharmacology, pharmacokinetics, pharmacodynamics, clinical efficacy, and safety profile...

..The optimal 6-h threshold for comparison depends upon indication for referral...

..44; 95% confidence interval, 0.42-0.46). Evaluation of national prescribing trends indicates that hydrochlorothiazide remains the most commonly prescribed thiazide, but there appears to be a shift toward more new users of chlorthalidone...

..Our findings on left ventricular hypertrophy support the idea that greater blood pressure reduction with CTD than HCTZ may have led to differences in mortality observed in the Multiple Risk Factor Intervention Trial...

..Medicare recently announced plans to begin reimbursement for ABPM, which will likely increase demand for ABPM services. Clinicians should become familiar with the role of this technology in the care of the hypertensive patient...

..Studies in the past 25 years have suggested that physicians are not familiar with the costs of common prescription medications...

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..The objective of this study was to determine the relationship between drug-related problems (DRPs) and health-related quality-of-life (HRQoL) in ambulatory, community-dwelling patients with musculoskeletal disorders...

..Clinicians involved in the care of patients with hypertension should familiarize themselves with the role of this technology and how to use it in an appropriate and cost-effective manner...

..To increase accessibility of influenza vaccine in a rural community by establishing a community pharmacy-based influenza vaccination program...

..To examine patients' acceptance and reported use of traditional and nontraditional immunization providers and settings...

..To review the literature examining the use of methylxanthines in the treatment of anaphylaxis...

..Until the results of these studies are repeated in more diverse patient populations, corticosteroids appear to have a limited role in the management of acute neuralgia associated with herpes zoster...

..Before antifungal time-kill curve methods are routinely employed by investigators, methodology should be scrutinized and standardized procedures should be developed...

..However, there is little information about physician interest in collaborating with nonphysicians to provide out-of-office immunizations...

..To determine whether community pharmacists can use point-of-service health status assessments to identify and resolve drug-related problems (DRPs) in ambulatory patients with selected musculoskeletal (MSK) disorders...

..5 to 2.0 times as potent as hydrochlorothiazide, and the former has a much longer duration of action. Whether these pharmacokinetic and pharmacodynamic features cause differences in outcomes is not known...

..Addition of centrally acting agents, alpha blockers, or vasodilators may also be necessary...

..Upper respiratory tract illnesses (URTI) are known to cause measurable decline in health-related quality of life (HRQL). We studied whether antibiotics impacted patients' HRQL after obtaining medical care for URTI...

..e., time-kill curves and MFCs, we suggest that 80% reduction in visible growth be utilized as the endpoint for susceptibility determinations with LY303366 in RPMI medium...

..To review the epidemiology, pathophysiology, clinical manifestations, diagnosis, and management of tetanus and its complications...

..To examine the influence of specific patient characteristics on the success of ambulatory blood pressure monitoring (ABPM)...

..The aim of this study is to describe recommendations made by clinical pharmacists when co-managing hypertension with physicians...

..Of those reviewed here, CoQ10 appears to provide some minor treatment benefits. More study is necessary to determine whether CoQ10 has a significant role as primary or adjunctive therapy in PD...

..While increasing patients' access to medications is necessary, the results of this study suggest that this in itself is not sufficient to ensure good BP control...

..CONCLUSIONS: Although further studies are warranted, preliminary data suggest that SSRIs are generally modestly successful in reducing the frequency and severity of hot flashes...

..CONCLUSIONS: Results indicate that routine capture of patient-reported health outcomes data is feasible in community pharmacy settings using touch screen technology...