- CaMKII in the cardiovascular system: sensing redox statesJeffrey R Erickson
Department of Pharmacology, University of California at Davis, Davis, California 95616, USA
Physiol Rev 91:889-915. 2011....
- CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca(2+) leak and the pathophysiological response to chronic β-adrenergic stimulationMichael Grimm
Department of Pharmacology, University of California, San Diego, CA, USA
J Mol Cell Cardiol 85:282-91. 2015....
- Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytesLaetitia Pereira
Department of Pharmacology, University of California, Davis, CA 95616
Proc Natl Acad Sci U S A 112:3991-6. 2015..In conclusion, Epac1 is localized and functionally involved in nuclear signaling, whereas Epac2 is located at the T tubules and regulates arrhythmogenic sarcoplasmic reticulum Ca leak. ..
- Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylationJeffrey R Erickson
Department of Pharmacology, University of California, Davis, Davis, California 95616, USA
Nature 502:372-6. 2013..Thus, O-GlcNAc modification of CaMKII is a novel signalling event in pathways that may contribute critically to cardiac and neuronal pathophysiology in diabetes and other diseases. ..