Research Topics
Species | John W ErdmanSummaryAffiliation: University of Illinois Country: USA Publications
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Publications
How do nutritional and hormonal status modify the bioavailability, uptake, and distribution of different isomers of lycopene?John W Erdman
Department of Food Science and Human Nutrition, University of Illinois, Urbana, 61801, USA
J Nutr 135:2046S-7S. 2005- Not all soy products are created equal: caution needed in interpretation of research resultsJohn W Erdman
Department of Food Science and Human Nutrition, University of Illinois, Urbana, IL 61801, USA
J Nutr 134:1229S-1233S. 2004..Efforts are needed by all to reduce the public confusion by adapting standardized approaches to the reporting of data. This paper provides a framework for both standardization of nomenclature and appropriate interpretation of data... - Effects of cocoa flavanols on risk factors for cardiovascular diseaseJohn W Erdman
University of Illinois, Food Science and Human Nutrition, 455 Bevier Hall, 905 South Goodwin Ave, Urbana, IL 61801, USA
Asia Pac J Clin Nutr 17:284-7. 2008.... - Isolated soy protein consumption reduces urinary albumin excretion and improves the serum lipid profile in men with type 2 diabetes mellitus and nephropathySandra R Teixeira
Division of Nutritional Sciences, University of Illinois at Urbana-Champaign (UIUC, Urbana, IL 61801, USA
J Nutr 134:1874-80. 2004..326), and O-desmethylangolesin (rho = -0.389) (P < 0.05). The findings indicate that isolated soy protein consumption improves several markers that may be beneficial for type 2 diabetic patients with nephropathy... 
Lycopene biodistribution is altered in 15,15'-carotenoid monooxygenase knockout miceBrian L Lindshield
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 138:2367-71. 2008..In conclusion, CMO I KO mice fed low levels of vitamin A have altered lycopene biodistribution and isomer patterns and do not cleave beta-carotene to vitamin A at appreciable levels...- Daily consumption of a dark chocolate containing flavanols and added sterol esters affects cardiovascular risk factors in a normotensive population with elevated cholesterolRobin R Allen
Department of Food Science and Human Nutrition, University of Illinois, Urbana Champaign, USA
J Nutr 138:725-31. 2008..8 mm Hg; P < 0.05). Results indicate that regular consumption of chocolate bars containing PS and CF as part of a low-fat diet may support cardiovascular health by lowering cholesterol and improving blood pressure... - The biodistribution of a single oral dose of [14C]-lycopene in rats prefed either a control or lycopene-enriched dietSusan Zaripheh
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 135:2212-8. 2005..These data suggest that lyc absorption, tissue uptake, and catabolism were affected by prefeeding and that lyc can be partially taken up by extrahepatic tissues from the postprandial triglyceride-rich fraction... - The relative vitamin A value of 9-cis beta-carotene is less and that of 13-cis beta-carotene may be greater than the accepted 50% that of all-trans beta-carotene in gerbilsDenise M Deming
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 132:2709-12. 2002..Thus, the proportions of cis isomers of betaC contained in a food could negatively affect the vitamin A value of the diet... - Combinations of tomato and broccoli enhance antitumor activity in dunning r3327-h prostate adenocarcinomasKirstie Canene Adams
Division of Nutritional Sciences and Department of Food Science and Human Nutrition, University of Illinois, Urbana, Illinois 61801, and Department of Internal Medicine, James Cancer Hospital and Solove Research Institute, Columbus, Ohio, USA
Cancer Res 67:836-43. 2007..The combination of tomato and broccoli was more effective at slowing tumor growth than either tomato or broccoli alone and supports the public health recommendations to increase the intake of a variety of plant components... - Nutritional aspects of phytoene and phytofluene, carotenoid precursors to lycopeneNancy J Engelmann
Division of Nutritional Sciences University of Illinois Urbana Champaign, Urbana, IL 61801, USA
Adv Nutr 2:51-61. 2011.... - Tomato phytochemicals and prostate cancer riskJessica K Campbell
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 134:3486S-3492S. 2004.... 
Lycopene and apo-12'-lycopenal reduce cell proliferation and alter cell cycle progression in human prostate cancer cellsNikki A Ford
Division of Nutritional Sciences, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
Nutr Cancer 63:256-63. 2011..The present data indicate that lycopene and apo-12'-lycopenal reduce the proliferation of prostate cancer cells, in part, by inhibiting normal cell cycle progression...- Loss of carotene-9',10'-monooxygenase expression increases serum and tissue lycopene concentrations in lycopene-fed miceNikki A Ford
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 140:2134-8. 2010..In conclusion, the loss of CMO-II expression leads to increased serum and tissue concentrations of lycopene in tomato-fed mice... - Lycopenoids: are lycopene metabolites bioactive?Brian L Lindshield
Division of Nutritional Sciences, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Arch Biochem Biophys 458:136-40. 2007..Finally, we identify gaps in knowledge in this evolving area of carotenoid research... - Serum testosterone is reduced following short-term phytofluene, lycopene, or tomato powder consumption in F344 ratsJessica K Campbell
Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
J Nutr 136:2813-9. 2006..Overall, results illustrate that short-term intake of tomato carotenoids significantly alters androgen status, which may partially be a mechanism by which tomato intake reduces prostate cancer risk... - An interaction between carotene-15,15'-monooxygenase expression and consumption of a tomato or lycopene-containing diet impacts serum and testicular testosteroneNikki A Ford
Division of Nutritional Sciences, University of Illinois Urbana Champaign, Urbana, IL 61801, USA
Int J Cancer 131:E143-8. 2012..Furthermore, carefully controlled studies with tomato products and lycopene in genetically defined murine models may elucidate important diet × genetic interactions that may impact prostate cancer risk... - Contrast ultrasound imaging of the aorta alters vascular morphology and circulating von Willebrand factor in hypercholesterolemic rabbitsBrendon W Smith
Division of Nutritional Sciences, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
J Ultrasound Med 31:711-20. 2012..We used a cholesterol-fed rabbit model to evaluate these effects when used in conjunction with ultrasound (US) to image the descending aorta... - Combined consumption of soy germ and tomato powders results in altered isoflavone and carotenoid bioavailability in ratsKrystle E Zuniga
Division of Nutritional Sciences, Department of Food Science and Human Nutrition, University of Illinois at Urbana Champaign, Urbana, Illinois, United States
J Agric Food Chem 59:5335-41. 2011..The results suggest interactions between soy germ and tomato powder that enhance isoflavone absorption but reduce carotenoid bioavailability... - Differential effects of blueberry proanthocyanidins on androgen sensitive and insensitive human prostate cancer cell linesBarbara M Schmidt
Department of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign, 1201 S. Dorner Dr, Urbana, IL 61801, USA
Cancer Lett 231:240-6. 2006..Possible molecular mechanisms for growth inhibition are reviewed... - Dietary lycopene downregulates carotenoid 15,15'-monooxygenase and PPAR-gamma in selected rat tissuesSusan Zaripheh
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 136:932-8. 2006..These data suggest that lycopene may play an important role in the modulation of beta-carotene, retinoid, and/or lipid metabolism... - Herbicide treatments alter carotenoid profiles for 14C tracer production from tomato ( Solanum lycopersicum cv. VFNT cherry) cell culturesNancy J Engelmann
Division of Nutritional Sciences, University of Illinois, Urbana Champaign, Urbana, Illinois 61801, USA
J Agric Food Chem 57:4614-9. 2009..Improved culture conditions efficiently provided sufficient (14)C-carotenoids for future cell culture and animal metabolic tracking studies... - Apo-8'-lycopenal and apo-12'-lycopenal are metabolic products of lycopene in rat liverMarija Gajic
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 136:1552-7. 2006..Apo-8'-lycopenal and the putative apo-12'-lycopenal are identified as lycopene metabolites in rat liver in vivo... - Screening and selection of high carotenoid producing in vitro tomato cell culture lines for [13C]-carotenoid productionNancy J Engelmann
Division of Nutritional Sciences, 905 South Goodwin Avenue, University of Illinois Urbana Champaign, Urbana, Illinois 61801, USA
J Agric Food Chem 58:9979-87. 2010..To the authors' knowledge this is the first report of highly enriched 13C-carotenoid production from in vitro plant cell culture... - Feeding tomato and broccoli powders enriched with bioactives improves bioactivity markers in ratsAnn G Liu
Division of Nutritional Sciences and Department of Food Science and Human Nutrition, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
J Agric Food Chem 57:7304-10. 2009..Enhancing bioactive content of tomatoes and broccoli may enhance efficacy in the prevention of prostate cancer... - The tomato as a functional foodKirstie Canene-Adams
Department of Food Science and Human Nutrition and the Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
J Nutr 135:1226-30. 2005.... - Laboratory-scale production of 13C-labeled lycopene and phytoene by bioengineered Escherichia coliChi Hua Lu
Department of Food Science and Human Nutrition, University of Illinois at Urbana Champaign, 905 South Goodwin Avenue, Urbana, Illinois 61801, United States
J Agric Food Chem 59:9996-10005. 2011..The development of this production model will provide carotenoid researchers a source of labeled tracer materials to further investigate the metabolism and biological functions of these carotenoids... - [14C]-lycopene and [14C]-labeled polar products are differentially distributed in tissues of F344 rats prefed lycopeneSusan Zaripheh
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 133:4189-95. 2003..The percentage and amount of 14C-polar products in the dorsolateral prostate lobe increased from 3 to 24 h and then reached a plateau. The data suggest that lycopene may be metabolized differently among tissues in rats prefed lycopene... - Optimization of lycopene extraction from tomato cell suspension culture by response surface methodologyChi Hua Lu
Department of Food Science and Human Nutrition, University of Illinois at Urbana Champaign, Urbana, Illinois 61801, USA
J Agric Food Chem 56:7710-4. 2008..56 mL of ethanol, 28 s homogenization, 0.29 mL of KOH, 2.49 mL of hexane, and 17.5 s vortex. These optimal conditions predicted by RSM were confirmed to enhance lycopene yield from standardized tomato cell cultures by more than 3-fold... - Are the health attributes of lycopene related to its antioxidant function?John W Erdman
Department of Food Science and Human Nutrition, 449 Bevier Hall, 905 S Goodwin Avenue, University of Illinois, Urbana, IL 61801, USA
Arch Biochem Biophys 483:229-35. 2009..Our laboratory has postulated that metabolic products of lycopene, the lycopenoids, may be responsible for some of lycopene's reported bioactivity... - Lycopene and apo-10'-lycopenal do not alter DNA methylation of GSTP1 in LNCaP cellsAnn G Liu
Division of Nutritional Sciences and Department of Food Science and Human Nutrition, 905 S Goodwin Avenue, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Biochem Biophys Res Commun 412:479-82. 2011..These findings demonstrate that lycopene and apo-10'-lycopenal are not effective demethylating agents of GSTP1 in the human LNCaP cell line... - Use of portion-controlled entrees enhances weight loss in womenSandra M Hannum
Food Science and Human Nutrition FSHN Nutritional Sciences Division, University of Illinois, Urbana, Illinois 61801, USA
Obes Res 12:538-46. 2004..S. Department of Agriculture Food Guide Pyramid (FGP) (United States Department of Agriculture, Center for Nutrition Policy and Promotion, Washington, DC; 1996)... - Effective separation of potent antiproliferation and antiadhesion components from wild blueberry (Vaccinium angustifolium Ait.) fruitsBarbara M Schmidt
Department of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign, 1201 South Dorner Drive, Urbana, Illinois 61801, USA
J Agric Food Chem 52:6433-42. 2004..These findings suggest both antiadhesion and antiproliferation activity are associated with high molecular weight proanthocyanidin oligomers found in wild blueberry fruits... - Inadequate dietary magnesium intake increases atherosclerotic plaque development in rabbitsJennifer L King
Bioacoustics Research Laboratory, Department of Electrical and Computer Engineering, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Nutr Res 29:343-9. 2009..This study supports the hypothesis that inadequate intake of Mg results in an increase in atherosclerotic plaque development in rabbits... - Presence of lunasin in plasma of men after soy protein consumptionVermont P Dia
Department of Food Science and Human Nutrition, University of Illinois, 228 ERML, MC 051, 1201 West Gregory Drive, Urbana, Illinois 61801, and Nutritional Sciences and Toxicology, University of California, Berkeley, California 94720 3104
J Agric Food Chem 57:1260-6. 2009..No peptides from lunasin were present in plasma samples without soy intake. The results of this study suggest that lunasin is bioavailable in humans, an important requirement for its anticancer potential... - All-trans beta-carotene appears to be more bioavailable than 9-cis or 13-cis beta-carotene in gerbils given single oral doses of each isomerDenise M Deming
Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
J Nutr 132:2700-8. 2002..05) and liver (P < 0.01) compared with those intubated with 13cbetaC. Because of its preferential uptake, transport and tissue accumulation, atbetaC appears to be a more bioavailable isomer than 9cbetaC or 13cbetaC in gerbils... - Altering dietary protein type and quantity reduces urinary albumin excretion without affecting plasma glucose concentrations in BKS.cg-m +Lepr db/+Lepr db (db/db) miceSandra R Teixeira
Division of Nutritional Sciences, University of Illinois at Urbana Champaign, 61801, USA
J Nutr 133:673-8. 2003..These findings show lower urinary albumin excretion when a soy protein diet or a low casein diet is fed, suggesting a delay in the progression of diabetic nephropathy... - Biosynthesis and characterization of 14C-enriched flavonoid fractions from plant cell suspension culturesGad G Yousef
Department of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign, 1201 South Dorner Drive, Urbana, Illinois 61801, USA
J Agric Food Chem 52:1138-45. 2004..The labeled phytochemicals were produced for use in subsequent in vivo animal feeding studies to gauge their bioavailability and accumulation in target organs... - Factors that influence the bioavailablity of xanthophyllsSusan Zaripheh
Division of Nutritional Sciences and Department of Food Science and Human Nutrition, University of Illinois, Urbana-Champaign, IL 61801, USA
J Nutr 132:531S-534S. 2002 - Flavonoids and heart health: proceedings of the ILSI North America Flavonoids Workshop, May 31-June 1, 2005, Washington, DCJohn W Erdman
University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
J Nutr 137:718S-737S. 2007..Data presented support the concept that certain flavonoids in the diet can be associated with significant health benefits, including heart health. Research gaps were identified to help advance the science... - Bioavailability of all-trans and cis-isomers of lycopeneThomas W-M Boileau
Department of Human Nutrition and Food Management, The Ohio State University, Columbus, OH 43210, USA
Exp Biol Med (Maywood) 227:914-9. 2002..Investigations are underway to determine whether there are biological differences between all-trans and various cis-isomers of lycopene regarding its antioxidant properties or other biological functions... - Relationship between plasma carotenoids and prostate cancerShine Chang
Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Nutr Cancer 53:127-34. 2005..These findings suggest that, in these men, higher circulating levels of alpha-cryptoxanthin, alpha-carotene, trans-beta-carotene, and lutein and zeaxanthin may contribute to lower prostate cancer risk but not to disease progression... - Biosynthesis of 14C-phytoene from tomato cell suspension cultures (Lycopersicon esculentum) for utilization in prostate cancer cell culture studiesJessica K Campbell
Division of Nutritional Sciences, University of Illinois at Urbana--Champaign, 905 South Goodwin Avenue, Illinois 61801, USA
J Agric Food Chem 54:747-55. 2006.... - Plasma and dietary carotenoids, and the risk of prostate cancer: a nested case-control studyKana Wu
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 13:260-9. 2004..In addition, our findings also suggest that among younger men, diets rich in beta-carotene may also play a protective role in prostate carcinogenesis... - Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted dietsThomas W-M Boileau
Division of Nutritional Sciences, University of Illinois, Urbana-Champaign, IL (TWMB, JWE
J Natl Cancer Inst 95:1578-86. 2003..Diet restriction also reduced the risk of prostate cancer. Tomato phytochemicals and diet restriction may act by independent mechanisms... - Variations in plasma lycopene and specific isomers over time in a cohort of U.S. menKana Wu
Department of Nutrition, Harvard School of Public Health, Boston, MA
J Nutr 133:1930-6. 2003..Single plasma samples quantitating plasma lycopene are a valid predictor of long-term exposure for epidemiologic studies... - Interrelationships among angiogenesis, proliferation, and apoptosis in the tumor microenvironment during N-methyl-N-nitrosourea androgen-induced prostate carcinogenesis in ratsZhiming Liao
Division of Hematology and Oncology, Department of Internal Medicine, The Ohio State University, College of Medicine and Public Health, A434 Starling Loving Hall, 320 West 10th Avenue, Columbus, OH 43210, USA
Carcinogenesis 23:1701-11. 2002..These biomarker changes are similar to those reported in human prostate carcinogenesis and represent potential biomarkers for the assessment of dietary, chemopreventive and therapeutic agents... - Tomato products, lycopene, and prostate cancer riskElizabeth C Miller
Division of Hematology and Oncology, James Cancer Hospital, Solove Research Institute, Ohio State University Medical Center, Columbus, OH, USA
Urol Clin North Am 29:83-93. 2002..The use of lycopene and other extracts for the treatment of prostate cancer is a separate issue that warrants individual attention and investigation...