Research Topics
Species | Elissa S EpelSummaryAffiliation: University of California Country: USA Publications
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Publications
Cell aging in relation to stress arousal and cardiovascular disease risk factorsElissa S Epel
UCSF Department of Psychiatry, San Francisco, CA, USA
Psychoneuroendocrinology 31:277-87. 2006..These findings may implicate telomerase as a novel and important mediator of the effects of psychological stress on physical health and disease...
Depression gets old fast: do stress and depression accelerate cell aging?Owen M Wolkowitz
Department of Psychiatry, University of California School of Medicine, San Francisco, California, USA
Depress Anxiety 27:327-38. 2010....
Stress appraisals and cellular aging: a key role for anticipatory threat in the relationship between psychological stress and telomere lengthAoife O'Donovan
Department of Psychiatry, University of California, San Francisco, CA, USA
Brain Behav Immun 26:573-9. 2012..Exaggerated anticipatory threat appraisals may be a common and modifiable psychological mechanism of psychological stress effects on cellular aging...
Accelerated telomere shortening in response to life stressElissa S Epel
Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 101:17312-5. 2004..These findings have implications for understanding how, at the cellular level, stress may promote earlier onset of age-related diseases...
Dynamics of telomerase activity in response to acute psychological stressElissa S Epel
Department of Psychiatry, University of California, San Francisco, 3333 Calif St, Suite 465, San Francisco, CA 94143, USA
Brain Behav Immun 24:531-9. 2010....
The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly menElissa S Epel
University of California, San Francisco, Department of Psychiatry, San Francisco, CA, 94143, USA
Aging (Albany NY) 1:81-8. 2008..0 (95% CI: 1.1 - 8.2). This is the first demonstration that rate of telomere length change (TLC) predicts mortality and thus may be a useful prognostic factor for longevity...
The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly menElissa S Epel
University of California, San Francisco, Department of Psychiatry, San Francisco, CA, 94143, USA
Aging (Albany NY) 1:81-8. 2009..0 (95% CI: 1.1 - 8.2). This is the first demonstration that rate of telomere length change (TLC) predicts mortality and thus may be a useful prognostic factor for longevity...
Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart diseaseRamin Farzaneh-Far
Division of Cardiology, Room 5G1, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
JAMA 303:250-7. 2010..Increased dietary intake of marine omega-3 fatty acids is associated with prolonged survival in patients with coronary heart disease. However, the mechanisms underlying this protective effect are poorly understood...
Psychological and metabolic stress: a recipe for accelerated cellular aging?Elissa S Epel
University of California, Department of Psychiatry, San Francisco, CA 94143, USA
Hormones (Athens) 8:7-22. 2009..Certain psychological temperaments at high risk of this stress cascade (mainly anxiety prone), gene-environment interactions, and potential interventions for interrupting the stress-aging cascade are discussed...
Telomere shortening in formerly abused and never abused womenJanice Humphreys
Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, CA 94143, USA
Biol Res Nurs 14:115-23. 2012..Findings from this descriptive study suggest a link between IPV exposure, duration of IPV-related stress, and telomere length molecular mechanisms that regulate cellular aging...
Positive affect uniquely predicts lower risk of mortality in people with diabetesJudith Tedlie Moskowitz
Osher Center for Integrative Medicine, University of California, San Francisco, CA 94115, USA
Health Psychol 27:S73-82. 2008..To determine whether positive affect predicts mortality among people with diabetes and among a comparison group of people with no chronic health conditions...
Leptin concentrations in response to acute stress predict subsequent intake of comfort foodsA Janet Tomiyama
Department of Psychology, UCLA, Los Angeles, CA, USA
Physiol Behav 107:34-9. 2012..Increasing leptin during the stressor predicted lower intake of comfort food. These initial findings suggest that acute changes in leptin may be one of the factors modulating down the consumption of comfort food following stress...
Glucocorticoids. Mood, memory, and mechanismsOwen M Wolkowitz
Department of Psychiatry, University of California San Francisco UCSF School of Medicine, San Francisco, California, USA
Ann N Y Acad Sci 1179:19-40. 2009..The article concludes with a conceptual model of glucocorticoid actions in the brain that may lead to novel therapeutic opportunities...
Shorter leukocyte telomere length in midlife women with poor sleep qualityAric A Prather
Robert Wood Johnson Foundation Health and Society Scholars Program, Center for Health and Community, University of California San Francisco, 3333 California Street, Suite 465, San Francisco, CA 94118, USA
J Aging Res 2011:721390. 2011..Conclusions. This study provides the first evidence that poor sleep quality explains significant variation in LTL, a marker of cellular aging...
Chronic stress elevates telomerase activity in ratsAnnaliese K Beery
Robert Wood Johnson Health and Society Scholar at University of California at San Francisco, San Francisco, CA 04143, USA
Biol Lett 8:1063-6. 2012..This significant increase suggests a potential mechanism for resilience to stress-related replicative senescence...
Exaggerated neurobiological sensitivity to threat as a mechanism linking anxiety with increased risk for diseases of agingAoife O'Donovan
Department of Psychiatry, University of California, San Francisco, CA, USA
Neurosci Biobehav Rev 37:96-108. 2013..Chronic inflammation, in turn, increases risk for diseases of aging. Exaggerated neurobiological sensitivity to threat may thus be a treatment target for reducing disease risk in anxious individuals...
Black sheep get the blues: a psychobiological model of social rejection and depressionGeorge M Slavich
Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143 0848, USA
Neurosci Biobehav Rev 35:39-45. 2010..This response also may be moderated by several factors, including prior life stress, prior depression, and genes implicated in stress reactivity...
Socioeconomic status in relation to early menarche among black and white girlsDejana Braithwaite
Department of Epidemiology and Biostatistics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 185 Berry Street, Lobby 4 Suite 5700, San Francisco, CA 94107, USA
Cancer Causes Control 20:713-20. 2009..Early menarche is a risk factor for breast cancer. We investigated the variation in age at menarche by socioeconomic status (SES) and race...
When blue turns to grey: do stress and depression accelerate cell aging?Owen M Wolkowitz
World J Biol Psychiatry 9:2-5. 2008
Flattened cortisol rhythms in metastatic breast cancer patientsHeather C Abercrombie
Department of Psychiatry, University of Wisconsin Medical School, 6001 Research Park Blvd, Madison, WI 53719, USA
Psychoneuroendocrinology 29:1082-92. 2004..These findings suggest that the cortisol diurnal slope may have important but different correlates in healthy women versus those with breast cancer...
Why egalitarianism might be good for your health: physiological thriving during stressful intergroup encountersWendy Berry Mendes
Department of Psychology, Harvard University, Cambridge, MA 02138, USA
Psychol Sci 18:991-8. 2007..Egalitarianism may have physical and psychological benefits for people living in a diverse society...
Sex differences in stress responses: social rejection versus achievement stressLaura R Stroud
Brown University Centers for Behavioral and Preventive Medicine, Providence, Rhode Island 02903, USA
Biol Psychiatry 52:318-27. 2002..Women's greater reactivity to rejection stress may contribute to the increased rates of affective disorders in women...
