Janet A Englund

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Safety and infectivity of two doses of live-attenuated recombinant cold-passaged human parainfluenza type 3 virus vaccine rHPIV3cp45 in HPIV3-seronegative young children
    Janet A Englund
    Seattle Children s Hospital, University of Washington, 4800 Sand Point Way NE, Seattle, WA 98105, United States Electronic address
    Vaccine 31:5706-12. 2013
  2. ncbi request reprint Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipients
    Janet A Englund
    Children s Hospital and Regional Medical Center, University of Washington, and Fred Hutchinson Cancer Research Center, Seattle, Washington 98105, USA
    Ann Intern Med 144:344-9. 2006
  3. ncbi request reprint Maternal immunization with Haemophilus influenzae type b vaccines in different populations
    Janet A Englund
    Department of Pediatrics, Children s Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE 8G, Seattle, WA 98105, USA
    Vaccine 21:3455-9. 2003
  4. ncbi request reprint Immunization with trivalent inactivated influenza vaccine in partially immunized toddlers
    Janet A Englund
    Pediatric ID, Children s Hospital and Regional Medical Center, 4800 Sand Point Way, NE W8851, Seattle, Washington 98105, USA
    Pediatrics 118:e579-85. 2006
  5. doi request reprint Safety and immunogenicity of trivalent inactivated influenza vaccine in infants: a randomized double-blind placebo-controlled study
    Janet A Englund
    Department of Pediatrics, Division of Infectious Diseases, Children s Hospital Research Institute, University of Washington, Seattle, WA, USA
    Pediatr Infect Dis J 29:105-10. 2010
  6. pmc Respiratory virus pneumonia after hematopoietic cell transplantation (HCT): associations between viral load in bronchoalveolar lavage samples, viral RNA detection in serum samples, and clinical outcomes of HCT
    Angela P Campbell
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    J Infect Dis 201:1404-13. 2010
  7. pmc Outcome of respiratory syncytial virus lower respiratory tract disease in hematopoietic cell transplant recipients receiving aerosolized ribavirin: significance of stem cell source and oxygen requirement
    Sachiko Seo
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Biol Blood Marrow Transplant 19:589-96. 2013
  8. pmc WU and KI polyomaviruses in respiratory samples from allogeneic hematopoietic cell transplant recipients
    Jane Kuypers
    University of Washington, Seattle, Washington 98102, USA
    Emerg Infect Dis 18:1580-8. 2012
  9. pmc Influenza viral RNA detection in blood as a marker to predict disease severity in hematopoietic cell transplant recipients
    Su Mi Choi
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Infect Dis 206:1872-7. 2012
  10. pmc Self-collection of foam nasal swabs for respiratory virus detection by PCR among immunocompetent subjects and hematopoietic cell transplant recipients
    Angela P Campbell
    University of Washington, Seattle, Washington, USA
    J Clin Microbiol 51:324-7. 2013

Detail Information

Publications60

  1. pmc Safety and infectivity of two doses of live-attenuated recombinant cold-passaged human parainfluenza type 3 virus vaccine rHPIV3cp45 in HPIV3-seronegative young children
    Janet A Englund
    Seattle Children s Hospital, University of Washington, 4800 Sand Point Way NE, Seattle, WA 98105, United States Electronic address
    Vaccine 31:5706-12. 2013
    ..Live-attenuated cold-adapted HPIV3 vaccines have been evaluated in infants but a suitable interval for administration of a second dose of vaccine has not been defined...
  2. ncbi request reprint Brief communication: fatal human metapneumovirus infection in stem-cell transplant recipients
    Janet A Englund
    Children s Hospital and Regional Medical Center, University of Washington, and Fred Hutchinson Cancer Research Center, Seattle, Washington 98105, USA
    Ann Intern Med 144:344-9. 2006
    ..Human metapneumovirus (hMPV), a recently discovered respiratory virus, is associated with clinical disease in young and elderly persons...
  3. ncbi request reprint Maternal immunization with Haemophilus influenzae type b vaccines in different populations
    Janet A Englund
    Department of Pediatrics, Children s Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE 8G, Seattle, WA 98105, USA
    Vaccine 21:3455-9. 2003
    ..Principles observed in these studies have potential application against other important neonatal pathogens...
  4. ncbi request reprint Immunization with trivalent inactivated influenza vaccine in partially immunized toddlers
    Janet A Englund
    Pediatric ID, Children s Hospital and Regional Medical Center, 4800 Sand Point Way, NE W8851, Seattle, Washington 98105, USA
    Pediatrics 118:e579-85. 2006
    ....
  5. doi request reprint Safety and immunogenicity of trivalent inactivated influenza vaccine in infants: a randomized double-blind placebo-controlled study
    Janet A Englund
    Department of Pediatrics, Division of Infectious Diseases, Children s Hospital Research Institute, University of Washington, Seattle, WA, USA
    Pediatr Infect Dis J 29:105-10. 2010
    ..Infants less than 6 months of age are at high risk for influenza disease and influenza-related complications, but no vaccine is licensed for this population...
  6. pmc Respiratory virus pneumonia after hematopoietic cell transplantation (HCT): associations between viral load in bronchoalveolar lavage samples, viral RNA detection in serum samples, and clinical outcomes of HCT
    Angela P Campbell
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    J Infect Dis 201:1404-13. 2010
    ..Few data exist on respiratory virus quantitation in lower respiratory samples and detection in serum from hematopoietic cell transplant (HCT) recipients with respiratory virus-associated pneumonia...
  7. pmc Outcome of respiratory syncytial virus lower respiratory tract disease in hematopoietic cell transplant recipients receiving aerosolized ribavirin: significance of stem cell source and oxygen requirement
    Sachiko Seo
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Biol Blood Marrow Transplant 19:589-96. 2013
    ..These results may explain differences in outcomes reported from RSV infection over time and may guide the design of future interventional trials...
  8. pmc WU and KI polyomaviruses in respiratory samples from allogeneic hematopoietic cell transplant recipients
    Jane Kuypers
    University of Washington, Seattle, Washington 98102, USA
    Emerg Infect Dis 18:1580-8. 2012
    ..There were no associations with polyomavirus detection and acute graft versus host disease, cytomegalovirus reactivation, neutropenia, lymphopenia, hospitalization, or death...
  9. pmc Influenza viral RNA detection in blood as a marker to predict disease severity in hematopoietic cell transplant recipients
    Su Mi Choi
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Infect Dis 206:1872-7. 2012
    ..Among patients with LRD, viremia was associated with increased hazards of overall and influenza-associated death (hazard ratio 3.5, 1.1-12). Thus, influenza viremia may serve as marker for overall poor outcome...
  10. pmc Self-collection of foam nasal swabs for respiratory virus detection by PCR among immunocompetent subjects and hematopoietic cell transplant recipients
    Angela P Campbell
    University of Washington, Seattle, Washington, USA
    J Clin Microbiol 51:324-7. 2013
    ..004), respectively, and those from 140 URI samples from hematopoietic cell transplantation recipients were 88% and 85% (P = 0.56), respectively...
  11. pmc Respiratory virus infection among hematopoietic cell transplant recipients: evidence for asymptomatic parainfluenza virus infection
    Angela J Peck
    Department of Pediatrics, Children s Hospital and Regional Medical Center and University of Washington, Seattle, WA, USA
    Blood 110:1681-8. 2007
    ..004). Subclinical infection with PIV may help explain why infection-control programs that emphasize symptoms are effective against RSV and influenza but often not against PIV...
  12. doi request reprint Trivalent inactivated influenza virus vaccine given to two-month-old children: an off-season pilot study
    Emmanuel B Walter
    Department of Pediatrics, Duke University Medical Center, Durham, NC, USA
    Pediatr Infect Dis J 28:1099-104. 2009
    ..Although children less than 6 months of age have the highest risk for hospitalization related to influenza infection, influenza vaccine is not approved for these children...
  13. ncbi request reprint Influenza vaccine immunogenicity in 6- to 23-month-old children: are identical antigens necessary for priming?
    Emmanuel B Walter
    Duke Clinical Research Institute, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA
    Pediatrics 118:e570-8. 2006
    ....
  14. doi request reprint Implementation of filmarray respiratory viral panel in a core laboratory improves testing turnaround time and patient care
    Min Xu
    Dept of Laboratories, Seattle Children s Hospital, Seattle, WA 98105, USA
    Am J Clin Pathol 139:118-23. 2013
    ..Our results demonstrate that molecular technology can be successfully deployed in a nonspecialty, high-volume, multidisciplinary core laboratory...
  15. ncbi request reprint Safety and tolerability of oseltamivir prophylaxis in hematopoietic stem cell transplant recipients: a retrospective case-control study
    Debie Vu
    Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 1024, USA
    Clin Infect Dis 45:187-93. 2007
    ..However, no data exist regarding the use of oseltamivir as prophylaxis among patients undergoing hematopoietic stem cell transplantation (HSCT)...
  16. pmc Human rhinovirus and coronavirus detection among allogeneic hematopoietic stem cell transplantation recipients
    Filippo Milano
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Blood 115:2088-94. 2010
    ..HRV and HCoV infections are common in the first 100 days after HCT, viral shedding lasts more than 3 weeks in half, and lower respiratory infection is rare...
  17. pmc Mortality rates of human metapneumovirus and respiratory syncytial virus lower respiratory tract infections in hematopoietic cell transplantation recipients
    Christian Renaud
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Biol Blood Marrow Transplant 19:1220-6. 2013
    ..Thus, HMPV lower respiratory tract disease is associated with high mortality in HCT recipients. Earlier detection in combination with new antiviral therapy is needed to reduce mortality among HCT recipients. ..
  18. doi request reprint Influenza-associated morbidity in children with cancer
    Sarah K Tasian
    Department of Pediatrics, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98105, USA
    Pediatr Blood Cancer 50:983-7. 2008
    ..The clinical impact of influenza in children undergoing therapy for cancer is not well-described in the literature...
  19. doi request reprint Combination therapy with amantadine, oseltamivir and ribavirin for influenza A infection: safety and pharmacokinetics
    Sachiko Seo
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Antivir Ther 18:377-86. 2013
    ..A triple-combination antiviral drug (TCAD) regimen consisting of amantadine (AMT), oseltamivir (OSL) and ribavirin (RBV) demonstrated good efficacy in an animal model...
  20. doi request reprint Clinical disease and viral load in children infected with respiratory syncytial virus or human metapneumovirus
    Emily T Martin
    Children s Hospital and Regional Medical Center, Seattle, WA 98105, USA
    Diagn Microbiol Infect Dis 62:382-8. 2008
    ..Our study has described a significant relationship between viral load and markers of disease severity for both RSV and hMPV in a large population of children evaluated for respiratory disease...
  21. doi request reprint Antiviral therapy of respiratory viruses in haematopoietic stem cell transplant recipients
    Christian Renaud
    Seattle Children s Hospital, Seattle, WA, USA
    Antivir Ther 17:175-91. 2012
    ..Finally, new drugs have been developed to treat influenza virus, respiratory syncytial virus, parainfluenza virus and adenovirus with some promising results...
  22. doi request reprint A prospective study of parainfluenza virus type 4 infections in children attending daycare
    Mary P Fairchok
    Department of Pediatrics, Madigan Army Medical Center, Tacoma, WA 98431, USA
    Pediatr Infect Dis J 30:714-6. 2011
    ..PIV-4 was second only to PIV-3, occurring in 9 of 87 (10%) PIV+ illnesses. PIV-4 illnesses were not more severe and not associated with a specific clinical syndrome...
  23. ncbi request reprint A comparison of 2 influenza vaccine schedules in 6- to 23-month-old children
    Janet A Englund
    Division of Pediatric Infectious Diseases, Allergy, and Rheumatology, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98105, USA
    Pediatrics 115:1039-47. 2005
    ..Trivalent inactivated influenza vaccine (TIV) is recommended for all children ages 6 to 23 months. Delivering 2 doses of TIV at least 4 weeks apart to young children receiving this vaccine for the first time is challenging...
  24. doi request reprint Respiratory viruses in children with cystic fibrosis: viral detection and clinical findings
    Jane L Burns
    Department of Pediatrics, Division of Infectious Diseases, University of Washington and Seattle Children s Hospital, USA
    Influenza Other Respir Viruses 6:218-23. 2012
    ..In addition, associations between viral detection and respiratory symptoms are not well described...
  25. pmc Frequent and prolonged shedding of bocavirus in young children attending daycare
    Emily T Martin
    Center for Clinical and Translational Research, Seattle Children s Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA
    J Infect Dis 201:1625-32. 2010
    ..Little is known about human bocavirus (HBoV) persistence and shedding and the association between HBoV detection and the onset and resolution of respiratory symptoms...
  26. doi request reprint Trivalent inactivated influenza vaccine (TIV) immunogenicity in children 6 through 23 months of age: do children of all ages respond equally?
    Emmanuel B Walter
    Department of Pediatrics, Duke University Medical Center, Durham, NC, USA
    Vaccine 28:4376-83. 2010
    ..The role of age should be considered when assessing improved vaccines to enhance TIV immunogenicity and effectiveness in younger children...
  27. ncbi request reprint Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immunodeficiency virus infection
    Yae Jean Kim
    Division of Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Semin Respir Crit Care Med 28:222-42. 2007
    ..Clinicians should appreciate the potential for the development of antiviral resistance to influenza antivirals in immunocompromised patients...
  28. pmc H275Y mutant pandemic (H1N1) 2009 virus in immunocompromised patients
    Christian Renaud
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Emerg Infect Dis 17:653-60; quiz 765. 2011
    ..Emergence of oseltamivir resistance is frequent in immunocompromised patients infected with pandemic (H1N1) 2009 virus and can be associated with a wide range of clinical disease and viral kinetics...
  29. pmc Multiple viral respiratory pathogens in children with bronchiolitis
    Hilary E Stempel
    Seattle Children s Hospital Research Institute, University of Washington, Seattle, WA, USA
    Acta Paediatr 98:123-6. 2009
    ..The aim of the study was to describe the frequency of viral pathogens and relative frequency of co-infections in nasal specimens obtained from young children with bronchiolitis receiving care at a children's hospital...
  30. pmc Differences in clinical outcomes after 2009 influenza A/H1N1 and seasonal influenza among hematopoietic cell transplant recipients
    Su Mi Choi
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Blood 117:5050-6. 2011
    ..Thus, our data suggest that infection with 2009 influenza A/H1N1 resulted in more severe respiratory disease in HCT recipients compared with seasonal influenza...
  31. ncbi request reprint Coronavirus-associated pneumonia in previously healthy children
    Judson Heugel
    Department of Pediatrics, University of Washington and Children s Hospital and Regional Medical Center, Seattle, WA, USA
    Pediatr Infect Dis J 26:753-5. 2007
    ..Here, we document the clinical courses of 2 previously healthy children with coronavirus-associated pneumonia...
  32. pmc Molecular epidemiology of respiratory syncytial virus transmission in childcare
    Helen Y Chu
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Clin Virol 57:343-50. 2013
    ..No prior studies using molecular techniques to examine RSV transmission in the community childcare setting have been performed...
  33. doi request reprint Emerging oseltamivir resistance in seasonal and pandemic influenza A/H1N1
    Christian Renaud
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Clin Virol 52:70-8. 2011
    ..However, immunocompromised patients infected with oseltamivir-resistant H1N1 experience potentially more risks of complication and transmissibility with few therapeutic options...
  34. doi request reprint Influenza vaccine for pregnant women in resource-constrained countries: a review of the evidence to inform policy decisions
    Justin R Ortiz
    Vaccine Development Global Program, PATH, Seattle, WA, United States
    Vaccine 29:4439-52. 2011
    ..Nonetheless, maternal influenza vaccination remains an important and potentially cost-effective approach to decrease influenza morbidity in two high-risk groups - pregnant women and young infants...
  35. ncbi request reprint Pertussis immunization in the global pertussis initiative North American region: recommended strategies and implementation considerations
    Tina Tan
    Division of Infectious Diseases, Northwestern University s Feinberg School of Medicine, The Children s Memorial Hospital, Chicago, IL 60614, USA
    Pediatr Infect Dis J 24:S83-6. 2005
    ....
  36. pmc Detection of bocavirus in saliva of children with and without respiratory illness
    Emily T Martin
    Center for Clinical and Translational Research, Seattle Children s Research Institute, Washington 98101, USA
    J Clin Microbiol 47:4131-2. 2009
    ..hBoV was detected in saliva samples at asymptomatic enrollment in 3% (5/149) and during respiratory illness in 2% (2/106) of the cases. hBoV was detected in only 1/149 asymptomatic and 0/106 illness nasal samples...
  37. pmc Development of a symptom score for clinical studies to identify children with a documented viral upper respiratory tract infection
    James A Taylor
    Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
    Pediatr Res 68:252-7. 2010
    ..9%, and accuracy of 73.3%. Parental impression is only a moderately accurate predictor of viral URI in children. Our URI symptom score provided a more accurate method for identifying children with viral URIs for clinical studies...
  38. doi request reprint Emergence of oseltamivir-resistant pandemic H1N1 in an immunocompetent child with severe status asthmaticus
    Christian Renaud
    Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Asthma 48:572-5. 2011
    ..Pandemic influenza A (H1N1) may cause severe illness in pediatric patient with chronic lung disease...
  39. pmc Prevalence and mechanisms of broad-spectrum beta-lactam resistance in Enterobacteriaceae: a children's hospital experience
    Xuan Qin
    Department of Laboratory Medicine, Microbiology Laboratory, Children s Hospital and Regional Medical Center, NE, Seattle, WA 98105 0371, USA
    Antimicrob Agents Chemother 52:3909-14. 2008
    ..These data have important implications for empirical antimicrobial strategies targeting serious pediatric infections. Further study of this problem is warranted...
  40. doi request reprint Hospital-based influenza vaccination of children: an opportunity to prevent subsequent hospitalization
    Danielle M Zerr
    Children s Research Institute, and Children s Hospital and Regional Medical Center, Seattle, WA 98105, USA
    Pediatrics 121:345-8. 2008
    ..We performed this study to determine the frequency of previous hospitalization among children hospitalized with influenza...
  41. ncbi request reprint Clinical disease in children associated with newly described coronavirus subtypes
    Jane Kuypers
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Pediatrics 119:e70-6. 2007
    ..In this study we examined the prevalence of 4 human coronaviruses, including subtypes OC43, 229E, and the recently described NL63 and HKU1 in a pediatric population presenting to a children's hospital...
  42. pmc Multitarget PCR for diagnosis of pertussis and its clinical implications
    Xuan Qin
    Microbiology Laboratory, Department of Laboratories and Pathology, A9601, Children s Hospital and Regional Medical Center, Seattle, WA 98105, USA
    J Clin Microbiol 45:506-11. 2007
    ..This consensus generating real-time PCR approach permits a sensitive detection, as well as an accurate species identification of the causative Bordetella pathogens for the timely management of patients...
  43. pmc BK nephropathy in pediatric hematopoietic stem cell transplant recipients
    Priya S Verghese
    Department of Pediatrics, University of Washington and Seattle Children s Hospital, Seattle, WA 98105, USA
    Pediatr Transplant 13:913-8. 2009
    ....
  44. ncbi request reprint Maternal immunization with inactivated influenza vaccine: rationale and experience
    Janet A Englund
    Department of Pediatrics, Children s Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE 8G, Seattle, WA 98105, USA
    Vaccine 21:3460-4. 2003
    ..Increased influenza vaccine use during pregnancy has the potential to benefit both the woman and her infant...
  45. ncbi request reprint Breakthrough fungal infections in stem cell transplant recipients receiving voriconazole
    Alexander Imhof
    Program in Infectious Diseases, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Clin Infect Dis 39:743-6. 2004
    ..Minimal inhibitory concentrations were > or =1 microg/mL for all available isolates. Yeasts and molds with decreased susceptibility to voriconazole may cause invasive infection in patients treated successfully for aspergillosis...
  46. ncbi request reprint Growth, survival and viral load in symptomatic childhood human immunodeficiency virus infection
    Caroline J Chantry
    Department of Pediatrics, University of California Davis Medical Center, Sacramento 95817, USA
    Pediatr Infect Dis J 22:1033-9. 2003
    ..The relationships among weight and height growth, viral load and survival in HIV-infected children remain unclear...
  47. doi request reprint Respiratory syncytial virus disease: prevention and treatment
    Helen Y Chu
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA, USA
    Curr Top Microbiol Immunol 372:235-58. 2013
    ....
  48. pmc Outcomes and duration of Pneumocystis jiroveci pneumonia therapy in infants with severe combined immunodeficiency
    Ingrid S Lundgren
    Division of Infectious Diseases, Seattle Children s Hospital, Seattle, WA 98105, USA
    Pediatr Infect Dis J 31:95-7. 2012
    ..We found that 80% of patients receiving only 21 days of antibiotics survived to 12 months beyond hematopoietic cell transplant, whereas only 25% of patients who required longer treatment for PCP survived to stem cell engraftment...
  49. ncbi request reprint Effectiveness of school-based influenza vaccination
    James C King
    Department of Pediatrics, University of Maryland School of Medicine, 737 W Lombard St, Baltimore, MD 21201, USA
    N Engl J Med 355:2523-32. 2006
    ..Vaccination of children in school is one strategy to reduce the spread of influenza in households and communities...
  50. ncbi request reprint Pandoraea bacteremia in a cystic fibrosis patient with associated systemic illness
    Lindsey N Johnson
    Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA
    Pediatr Infect Dis J 23:881-2. 2004
    ..We describe a case of Pandoraea bacteremia in a 16-year-old cystic fibrosis patient associated with clinical disease, suggesting that this organism should be considered a true pathogen in susceptible patients...
  51. ncbi request reprint Influenza A pneumonia presenting as progressive focal infiltrates in a stem cell transplant recipient
    John D Scott
    Department of Medicine, University of Washington, Harborview Medical Center, 325 Ninth Avenue, Box 359938, Seattle, WA 98104 2499, USA
    J Clin Virol 31:96-9. 2004
    ..Stem cell transplant recipients are susceptible to pulmonary infections, including influenza A. Typically, isolated influenza pneumonia has a diffuse, interstitial infiltrate pattern...
  52. ncbi request reprint Antiviral therapy of influenza
    Janet A Englund
    Department of Pediatrics, University of Chicago, Chicago, IL 60637, USA
    Semin Pediatr Infect Dis 13:120-8. 2002
    ..No direct comparisons of any of these antiviral agents has been performed; all result in clinical improvement approximately 1 to 2 days earlier in otherwise healthy children when therapy is initiated within 48 hours of onset of symptoms...
  53. ncbi request reprint Response to changes in antiretroviral therapy after genotyping in human immunodeficiency virus-infected children
    Nicole J Cohen
    Department of Pediatrics, University of Chicago Hospitals, IL, USA
    Pediatr Infect Dis J 21:647-53. 2002
    ..Our objectives were to evaluate the usefulness of genotyping in HIVinfected children failing HAART and to determine whether the presence of resistance mutations was associated with previous antiretroviral therapy...
  54. pmc Risk of bacterial infection in previously healthy respiratory syncytial virus-infected young children admitted to the intensive care unit
    Adrienne G Randolph
    Department of Anesthesia, Harvard Medical School, Boston, MA, USA
    Pediatr Infect Dis J 23:990-4. 2004
    ..To evaluate the risk of bacterial infection and use of antibiotics in otherwise healthy children infected with respiratory syncytial virus (RSV) admitted to the intensive care unit (ICU)...
  55. ncbi request reprint Influenza vaccine for young children: two doses are better than one
    Kathleen Maletic Neuzil
    J Pediatr 149:737-8. 2006
  56. ncbi request reprint Duration of immunity against pertussis after natural infection or vaccination
    Aaron M Wendelboe
    Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
    Pediatr Infect Dis J 24:S58-61. 2005
    ..Further research into the rate of waning of vaccine-acquired immunity will help determine the optimal timing and frequency of booster immunizations and their role in pertussis control...
  57. ncbi request reprint Surveillance of clinical isolates of respiratory syncytial virus for palivizumab (Synagis)-resistant mutants
    John P DeVincenzo
    University of Tennessee, LeBonheur Children s Medical Center, Memphis 38103, USA
    J Infect Dis 190:975-8. 2004
    ..Palivizumab bound to all 371 RSV isolates able to be evaluated, including 25 from active-palivizumab recipients. The palivizumab epitope appears to be highly conserved, even in infants receiving prophylaxis with palivizumab...
  58. ncbi request reprint Mutations linked to drug resistance, human immunodeficiency virus type 1 biologic phenotype and their association with disease progression in children receiving nucleoside reverse transcriptase inhibitors
    Janet A Englund
    University of Chicago, Pritzker School of Medicine, Chicago, IL, USA
    Pediatr Infect Dis J 23:15-22. 2004
    ..We evaluated the development of antiretroviral genotypic resistance and clinical outcome in a subgroup of children involved in a prospective antiretroviral therapy trial (Pediatric AIDS Clinical Trials Group Protocol 152)...
  59. ncbi request reprint Antimicrobial susceptibility of Bordetella pertussis isolates in the state of Washington
    Emmanouil Galanakis
    Int J Antimicrob Agents 29:609-11. 2007
  60. ncbi request reprint Role of maternal pertussis antibodies in infants
    Annelies Van Rie
    Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
    Pediatr Infect Dis J 24:S62-5. 2005
    ..The limited data on neonatal and maternal pertussis immunization are promising and call for further research to reduce the vulnerability of young infants to pertussis disease...