Research Topics
Genomes and GenesSpecies | Mary B EnglerSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Flavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adultsMary B Engler
Laboratory of Cardiovascular Physiology, Department of Physiological Nursing, University of California, San Francisco, 94143 0610, USA
J Am Coll Nutr 23:197-204. 2004..Cardioprotective effects including antioxidant properties, inhibition of platelet activity, and activation of endothelial nitric oxide synthase have been ascribed to the cocoa flavonoids...- Calcium-mediated mechanisms of eicosapentaenoic acid-induced relaxation in hypertensive rat aortaM B Engler
Department of Physiological Nursing, University of California, San Francisco 94143 0610, USA
Am J Hypertens 12:1225-35. 1999..These results suggest that EPA directly modulates intracellular Ca2+ signaling in VSM cells, and that this may contribute to the vasorelaxant effect and, at least in part, the blood pressure-lowering effect of fish oil... 
Mechanisms of vasorelaxation induced by eicosapentaenoic acid (20:5n-3) in WKY rat aortaM B Engler
University of California San Francisco, Laboratory of Cardiovascular Physiology, Department of Physiological Nursing, 2 Kirkham Street, Room N631, San Francisco, California, CA 94143 0610, USA
Br J Pharmacol 131:1793-9. 2000..Inhibition of Ca(2+) mobilization from intracellular pools and influx through the non-L-type, but not the L-type, Ca(2+) channel are also possible mechanisms action of EPA's...- The emerging role of flavonoid-rich cocoa and chocolate in cardiovascular health and diseaseMary B Engler
Department of Physiological Nursing, Laboratory of Cardiovascular Physiology, University of California, San Francisco, California 94143 0610, USA
Nutr Rev 64:109-18. 2006..Increasing evidence from experimental and clinical studies using cocoa-derived products and chocolate suggest an important role for these high-flavanol-containing foods in heart and vascular protection... 
Nutrigenomics in cardiovascular disease: implications for the futureMary B Engler
From the Department of Physiological Nursing, Laboratory of Cardiovascular Physiology, University of California, San Francisco, CA 94143 0610, USA
Prog Cardiovasc Nurs 24:190-5. 2009....- Genetic variation in phospholipid transfer protein modulates lipoprotein profiles in hyperalphalipoproteinemiaMary B Engler
Department of Physiological Nursing, University of California San Francisco, San Francisco, CA 94143, USA
Metabolism 57:1719-24. 2008..Linear regression models predict that possession of the rs2294213 minor allele increases HDL-C independent of triglycerides. These findings extend the association of rs2294213 with HDL-C levels into the extremes of the HDL distribution... - Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) TrialMarguerite M Engler
University of California, San Francisco, 2 Koret Way, Rm N631, San Francisco, Calif 94143 0610, USA
Circulation 108:1059-63. 2003..The purpose of this study was to determine whether antioxidant vitamin therapy improves endothelial function and affects surrogate biomarkers for oxidative stress and inflammation in hyperlipidemic children... - Effect of docosahexaenoic acid on lipoprotein subclasses in hyperlipidemic children (the EARLY study)Marguerite M Engler
University of California at San Francisco, San Francisco, California, USA
Am J Cardiol 95:869-71. 2005..Low-density lipoprotein subclass 3 (small and dense; more atherogenic particles) decreased by 48%... - Omega-3 fatty acids: role in cardiovascular health and diseaseMarguerite M Engler
Dept of Physiological Nursing, University of California San Francisco, 2 Koret Way, San Francisco, CA 94143 0610, USA
J Cardiovasc Nurs 21:17-24, quiz 25-6. 2006..The metabolism of omega-3 fatty acids, physiological effects, and clinical considerations with current dietary recommendations and sources of omega-3 fatty acids are presented... - Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acidZhigang Yu
Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, CA 94143, USA
J Pharmacol Exp Ther 317:732-8. 2006.... - Effects of docosahexaenoic acid on vascular pathology and reactivity in hypertensionMarguerite M Engler
Laboratory of Cardiovascular Physiology, Department of Physiological Nursing, University of California, San Francisco, California 94143 0610, USA
Exp Biol Med (Maywood) 228:299-307. 2003..This may contribute to decrease arterial stiffness and pulse pressure, in addition to the antihypertensive properties of DHA. The antihypertensive properties of DHA are not related to alterations in vascular responses... - IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contractionMakoto Kudo
Lung Biology Center, Department of Medicine, University of California, San Francisco, California, USA
Nat Med 18:547-54. 2012..These data indicate that the IL-17A produced by T(H)17 cells contributes to allergen-induced airway hyper-responsiveness through direct effects on airway smooth muscle... - Genetic variation of PLTP modulates lipoprotein profiles in hypoalphalipoproteinemiaBradley E Aouizerat
Department of Physiological Nursing, School of Nursing, University of California San Francisco, San Francisco, CA 94143, USA
J Lipid Res 47:787-93. 2006..R235W) of four (p.E72G, p.S119A, p.S124Y, and p.R235W) mutations in an in vitro activity assay. These findings indicate that PLTP gene variation is an important determinant of plasma lipoproteins and affects disorders of HDL metabolism...