Boris Engels

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. pmc Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity
    Boris Engels
    Department of Pathology, Committee on Immunology and Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637, USA
    Cancer Cell 23:516-26. 2013
  2. pmc Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity
    Boris Engels
    Department of Pathology, Committee on Immunology, The University of Chicago, Chicago, Illinois 60637 5420, USA
    Mol Ther 20:652-60. 2012
  3. pmc Targeting stroma to treat cancers
    Boris Engels
    Department of Pathology, Committee on Cancer Biology, Committee on Immunology, The University of Chicago, Chicago, IL 60637 5420, USA
    Semin Cancer Biol 22:41-9. 2012
  4. doi request reprint Spleen cells from young but not old immunized mice eradicate large established cancers
    Karin Schreiber
    Department of Pathology, The University of Chicago, Chicago, Illinois 60637, USA
    Clin Cancer Res 18:2526-33. 2012
  5. pmc IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner
    Rebecca Berlant Liu
    Committee on Immunology and Departments of Pathology, Medicine, and Pediatrics, University of Chicago, Chicago, IL 60637
    Proc Natl Acad Sci U S A 110:8158-63. 2013
  6. pmc Densely granulated murine NK cells eradicate large solid tumors
    Rebecca B Liu
    Committee on Immunology, Department of Pathology, The University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 72:1964-74. 2012

Collaborators

  • Bana Jabri
  • Michael T Spiotto
  • Ralph R Weichselbaum
  • Karin Schreiber
  • Hans Schreiber
  • Rebecca Berlant Liu
  • Andrea Schietinger
  • Rebecca B Liu
  • Ainhoa Arina
  • Donald A Rowley
  • Cezary Ciszewski
  • Alessandro Sette
  • Eric Butz
  • John Sidney
  • Theodore G Karrison
  • David C Binder
  • Elizabeth Hyjek
  • Thomas Krausz

Detail Information

Publications6

  1. pmc Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity
    Boris Engels
    Department of Pathology, Committee on Immunology and Committee on Cancer Biology, The University of Chicago, Chicago, IL 60637, USA
    Cancer Cell 23:516-26. 2013
    ..These findings highlight the importance of targeting peptides with high affinity for MHC class I when designing T cell-based immunotherapy...
  2. pmc Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity
    Boris Engels
    Department of Pathology, Committee on Immunology, The University of Chicago, Chicago, Illinois 60637 5420, USA
    Mol Ther 20:652-60. 2012
    ....
  3. pmc Targeting stroma to treat cancers
    Boris Engels
    Department of Pathology, Committee on Cancer Biology, Committee on Immunology, The University of Chicago, Chicago, IL 60637 5420, USA
    Semin Cancer Biol 22:41-9. 2012
    ..Therefore, we will also discuss conditions where stromal targeting can eradicate large established tumors. Finally, we will examine still unanswered questions of this promising and exciting area of cancer research...
  4. doi request reprint Spleen cells from young but not old immunized mice eradicate large established cancers
    Karin Schreiber
    Department of Pathology, The University of Chicago, Chicago, Illinois 60637, USA
    Clin Cancer Res 18:2526-33. 2012
    ..However, TCR-transgenic T cells and/or tumor cells overexpressing antigens are frequently used in these experiments. Here we studied the requirements for destroying clinical size, unmanipulated 8101 tumors by adoptive cell therapy...
  5. pmc IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner
    Rebecca Berlant Liu
    Committee on Immunology and Departments of Pathology, Medicine, and Pediatrics, University of Chicago, Chicago, IL 60637
    Proc Natl Acad Sci U S A 110:8158-63. 2013
    ....
  6. pmc Densely granulated murine NK cells eradicate large solid tumors
    Rebecca B Liu
    Committee on Immunology, Department of Pathology, The University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 72:1964-74. 2012
    ..These results indicate that IL-15 released at the cancer site induces highly activated NK cells that lead to eradication of large solid tumors...