Research Topics
Genomes and GenesSpecies | Corinne D EngelmanSummaryAffiliation: University of Wisconsin Country: USA Publications
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Publications
Vitamin D intake and season modify the effects of the GC and CYP2R1 genes on 25-hydroxyvitamin D concentrationsCorinne D Engelman
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
J Nutr 143:17-26. 2013....
The Survey of the Health of Wisconsin (SHOW), a novel infrastructure for population health research: rationale and methodsF Javier Nieto
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53726, USA
BMC Public Health 10:785. 2010..This manuscript describes the rationale and methods of the Survey of the Health of Wisconsin (SHOW), a novel infrastructure for population health research...
Detecting single-nucleotide polymorphism by single-nucleotide polymorphism interactions in rheumatoid arthritis using a two-step approach with machine learning and a Bayesian threshold least absolute shrinkage and selection operator (LASSO) modelOscar González-Recio
Department of Dairy Science, University of Wisconsin Madison, 266 Animal Science Building, 1675 Observatory Drive, Madison, Wisconsin 53706, USA
BMC Proc 3:S63. 2009..g., rs2395175, rs660895, rs10484560, and rs2476601). Further, some other SNPs detected in this study may be considered in candidate gene studies...
Genome-wide association studies using single-nucleotide polymorphisms versus haplotypes: an empirical comparison with data from the North American Rheumatoid Arthritis ConsortiumHeejung Shim
Department of Statistics, University of Wisconsin Madison, 1300 University Avenue, Madison, Wisconsin 53706 USA
BMC Proc 3:S35. 2009..Our results suggest that the application of both haplotype-based and individual-SNP testing to GWAS should be adopted as a routine procedure...
Classification tree for detection of single-nucleotide polymorphism (SNP)-by-SNP interactions related to heart disease: Framingham Heart StudyLi Yao
Department of Human Development and Family Studies, University of Wisconsin Madison, 1300 Linden Drive, Madison, Wisconsin 53706, USA
BMC Proc 3:S83. 2009..23%). Compared to class 16, all other classes except for class 288 (prevalence of 1.2%) had a significantly greater risk when analyzed using GEE model. This suggests the interactions of SNPs on these node paths are significant...
Genetic and environmental determinants of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels in Hispanic and African AmericansCorinne D Engelman
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, 610 Walnut Street, 1007A WARF, Madison, Wisconsin 53726 2397, USA
J Clin Endocrinol Metab 93:3381-8. 2008..Vitamin D deficiency is associated with many adverse health outcomes, yet little is known about the genetic epidemiology of vitamin D or its metabolites...
Detecting gene-environment interactions in genome-wide association dataCorinne D Engelman
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53726 2397, USA
Genet Epidemiol 33:S68-73. 2009....
Genome-wide association study of vitamin D concentrations in Hispanic Americans: the IRAS family studyCorinne D Engelman
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53726, USA
J Steroid Biochem Mol Biol 122:186-92. 2010..01). In conclusion, we identified several SNPs that were associated with vitamin D metabolite concentrations in Hispanics. These candidate polymorphisms merit further investigation in independent populations and other ethnicities...
Association of 25-hydroxyvitamin D with blood pressure in predominantly 25-hydroxyvitamin D deficient Hispanic and African AmericansKimberly J Schmitz
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
Am J Hypertens 22:867-70. 2009..This study investigates the association of 25-hydroxyvitamin D (25[OH]D) with blood pressure in Hispanic and African Americans...
Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease StudyKristin J Meyers
Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53726, USA
Invest Ophthalmol Vis Sci 54:2333-45. 2013..To investigate genetic determinants of macular pigment optical density in women from the Carotenoids in Age-Related Eye Disease Study (CAREDS), an ancillary study of the Women's Health Initiative Observational Study...
Analysis of human mini-exome sequencing data from Genetic Analysis Workshop 17 using a Bayesian hierarchical mixture modelJulio S Bueno Filho
Department of Population Health Sciences, University of Wisconsin Madison, 707 WARF Building, 610 North Walnut Street, Madison, WI 53726, USA
BMC Proc 5:S93. 2011..This project demonstrates the utility of Bayesian hierarchical mixture models using a transformed genotype matrix to detect genes containing rare and common variants associated with a binary phenotype...
Detecting gene-by-smoking interactions in a genome-wide association study of early-onset coronary heart disease using random forestsMatthew J Maenner
Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, 610 Walnut Street, Madison, Wisconsin 53705, USA
BMC Proc 3:S88. 2009..We sought to use the random forest algorithm to identify single-nucleotide polymorphisms (SNPs) that may be involved in gene-by-smoking interactions related to the early-onset of coronary heart disease...
