Patrick Emery

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi request reprint RNA extraction from Drosophila heads
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
    Methods Mol Biol 362:305-7. 2007
  2. ncbi request reprint Protein extraction from Drosophila heads
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
    Methods Mol Biol 362:375-7. 2007
  3. ncbi request reprint Ectopic CRYPTOCHROME renders TIM light sensitive in the Drosophila ovary
    Brandy L Rush
    Department of Zoology, Oregon State University, Corvallis, OR 97331, USA
    J Biol Rhythms 21:272-8. 2006
  4. doi request reprint Circadian rhythms: timing the sense of smell
    Patrick Emery
    University of Massachusetts Medical School, Department of Neurobiology, Worcester, Massachusetts 01605, USA
    Curr Biol 18:R569-71. 2008
  5. ncbi request reprint Glia got rhythm
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Neuron 55:337-9. 2007
  6. ncbi request reprint Interactions between circadian neurons control temperature synchronization of Drosophila behavior
    Ania Busza
    Department of Neurobiology and Program in Neuroscience, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    J Neurosci 27:10722-33. 2007
  7. pmc Light and temperature control the contribution of specific DN1 neurons to Drosophila circadian behavior
    Yong Zhang
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Curr Biol 20:600-5. 2010
  8. pmc A subset of dorsal neurons modulates circadian behavior and light responses in Drosophila
    Alejandro Murad
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Neuron 53:689-701. 2007
  9. pmc A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponses
    Raphaelle Dubruille
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    PLoS Genet 5:e1000787. 2009
  10. pmc A role for Drosophila ATX2 in activation of PER translation and circadian behavior
    Yong Zhang
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Science 340:879-82. 2013

Collaborators

Detail Information

Publications23

  1. ncbi request reprint RNA extraction from Drosophila heads
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
    Methods Mol Biol 362:305-7. 2007
    ..The procedure presented in this chapter is a rapid method to obtain a clean preparation of total RNA from fly heads that can be used for RNase protection, Northern blots, and real-time polymerase chain reaction (see Chapters 23-25)...
  2. ncbi request reprint Protein extraction from Drosophila heads
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
    Methods Mol Biol 362:375-7. 2007
    ..They can also be used for immunoprecipitation experiments...
  3. ncbi request reprint Ectopic CRYPTOCHROME renders TIM light sensitive in the Drosophila ovary
    Brandy L Rush
    Department of Zoology, Oregon State University, Corvallis, OR 97331, USA
    J Biol Rhythms 21:272-8. 2006
    ..Hence, CRY is the key component of the light input pathway missing in the ovary. However, the factors regulating PER and TIM levels downstream of light/cry action appear to be present in this non-circadian organ...
  4. doi request reprint Circadian rhythms: timing the sense of smell
    Patrick Emery
    University of Massachusetts Medical School, Department of Neurobiology, Worcester, Massachusetts 01605, USA
    Curr Biol 18:R569-71. 2008
    ..The kinase GPRK2 has now been identified as a critical link between the circadian clock and olfactory responses...
  5. ncbi request reprint Glia got rhythm
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Neuron 55:337-9. 2007
    ....
  6. ncbi request reprint Interactions between circadian neurons control temperature synchronization of Drosophila behavior
    Ania Busza
    Department of Neurobiology and Program in Neuroscience, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    J Neurosci 27:10722-33. 2007
    ..In conclusion, the behavioral responses to temperature input are determined by both the individual properties of specific groups of circadian neurons and their organization in a neural network...
  7. pmc Light and temperature control the contribution of specific DN1 neurons to Drosophila circadian behavior
    Yong Zhang
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Curr Biol 20:600-5. 2010
    ..Thus, the Clk4.1M-GAL4-positive DN1s, or the neurons they target, integrate light and temperature inputs to control locomotor rhythms. Our study therefore reveals a novel mechanism contributing to the plasticity of circadian behavior...
  8. pmc A subset of dorsal neurons modulates circadian behavior and light responses in Drosophila
    Alejandro Murad
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Neuron 53:689-701. 2007
    ..Thus, a subset of Dorsal Neurons shares with the LNvs the ability to function as pacemakers for circadian behavior, and its importance is promoted by light...
  9. pmc A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponses
    Raphaelle Dubruille
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    PLoS Genet 5:e1000787. 2009
    ..We therefore conclude that KIS is a key transcriptional regulator of genes that function in the CRY signaling cascade, and thus it plays an important role in the synchronization of circadian rhythms with the dayrationight cycle...
  10. pmc A role for Drosophila ATX2 in activation of PER translation and circadian behavior
    Yong Zhang
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Science 340:879-82. 2013
    ..Our work uncovers a role for ATX2 in circadian timing and reveals that this protein functions as an activator of PER translation in circadian neurons...
  11. pmc KAYAK-α modulates circadian transcriptional feedback loops in Drosophila pacemaker neurons
    Jinli Ling
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    J Neurosci 32:16959-70. 2012
    ..We propose that the double role of KAY-α in the two transcriptional loops controlling Drosophila circadian behavior brings precision and stability to their oscillations...
  12. doi request reprint A plastic clock: how circadian rhythms respond to environmental cues in Drosophila
    Raphaelle Dubruille
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Mol Neurobiol 38:129-45. 2008
    ..Here, we review our current knowledge of the molecular and neural mechanisms contributing to the plasticity of Drosophila circadian rhythms, which are proving to be remarkably sophisticated and complex...
  13. pmc Cryptochromes define a novel circadian clock mechanism in monarch butterflies that may underlie sun compass navigation
    Haisun Zhu
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
    PLoS Biol 6:e4. 2008
    ..Our data further suggest that CRY2 may have a dual role in the monarch butterfly's brain-as a core clock element and as an output that regulates circadian activity in the central complex, the likely site of the sun compass...
  14. pmc GW182 controls Drosophila circadian behavior and PDF-receptor signaling
    Yong Zhang
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Neuron 78:152-65. 2013
    ..We propose that GW182's gene silencing activity functions as a rheostat for PDFR signaling and thus profoundly impacts the circadian neural network and its response to environmental inputs...
  15. doi request reprint Circadian rhythms: An electric jolt to the clock
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Curr Biol 22:R876-8. 2012
    ..Surprisingly, a new study reports that electrical activity can reprogram circadian transcription, and identifies CREB proteins as candidates for this reprograming...
  16. ncbi request reprint Somatic localization of a specific large-conductance calcium-activated potassium channel subtype controls compartmentalized ethanol sensitivity in the nucleus accumbens
    Gilles Martin
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
    J Neurosci 24:6563-72. 2004
    ..Finally, an EtOH concentration (50 mm) that increased BK channel open probability strongly decreased the duration of somatic-generated action potential in NAcc neurons...
  17. ncbi request reprint Morning and evening oscillators cooperate to reset circadian behavior in response to light input
    Pallavi Lamba
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA Program in Neuroscience, Graduate School of Biomedical Sciences, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Cell Rep 7:601-8. 2014
    ..Hence, although photic TIM degradation is largely cell autonomous, neural cooperation between M and E oscillators is critical for circadian behavioral photoresponses. ..
  18. ncbi request reprint RNase protection assay
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
    Methods Mol Biol 362:343-8. 2007
    ..Methods to generate the riboprobes and to perform the RNase protection assay itself are described in this chapter...
  19. ncbi request reprint Mutagenesis with Drosophila
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
    Methods Mol Biol 362:187-95. 2007
    ..An alkylating agent can be used to randomly alter the fly genome, or transposable elements can be mobilized to disrupt or increase the expression of the targeted genes. The advantages of these different methods are complementary...
  20. ncbi request reprint A rhythmic Ror
    Patrick Emery
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, Massachusetts 01605, USA
    Neuron 43:443-6. 2004
    ..This finding defines the second feedback loop in mammals...
  21. ncbi request reprint Roles of the two Drosophila CRYPTOCHROME structural domains in circadian photoreception
    Ania Busza
    Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
    Science 304:1503-6. 2004
    ..This contrasts with the function of Arabidopsis CRY domains and demonstrates that insect and plant cryptochromes use different mechanisms...
  22. pmc PER-TIM interactions with the photoreceptor cryptochrome mediate circadian temperature responses in Drosophila
    Rachna Kaushik
    Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts, United States of America
    PLoS Biol 5:e146. 2007
    ..The results indicate a role for CRY in circadian temperature as well as light regulation and suggest that these two features of the external 24-h cycle normally act together to dictate circadian phase...
  23. ncbi request reprint Drosophila clock can generate ectopic circadian clocks
    Jie Zhao
    Howard Hughes Medical Institute, Department of Biology, Brandeis University, Waltham, MA 02454, USA
    Cell 113:755-66. 2003
    ..We propose that Clock is uniquely able to induce and organize the core elements of interdependent feedback loops necessary for circadian rhythms...