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Species | Patrick EmerySummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
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Publications
Protein extraction from Drosophila headsPatrick Emery
Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
Methods Mol Biol 362:375-7. 2007..They can also be used for immunoprecipitation experiments...- RNA extraction from Drosophila headsPatrick Emery
Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
Methods Mol Biol 362:305-7. 2007..The procedure presented in this chapter is a rapid method to obtain a clean preparation of total RNA from fly heads that can be used for RNase protection, Northern blots, and real-time polymerase chain reaction (see Chapters 23-25)... - Ectopic CRYPTOCHROME renders TIM light sensitive in the Drosophila ovaryBrandy L Rush
Department of Zoology, Oregon State University, Corvallis, OR 97331, USA
J Biol Rhythms 21:272-8. 2006..Hence, CRY is the key component of the light input pathway missing in the ovary. However, the factors regulating PER and TIM levels downstream of light/cry action appear to be present in this non-circadian organ... 
Circadian rhythms: timing the sense of smellPatrick Emery
University of Massachusetts Medical School, Department of Neurobiology, Worcester, Massachusetts 01605, USA
Curr Biol 18:R569-71. 2008..The kinase GPRK2 has now been identified as a critical link between the circadian clock and olfactory responses...- Glia got rhythmPatrick Emery
Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
Neuron 55:337-9. 2007.... - Interactions between circadian neurons control temperature synchronization of Drosophila behaviorAnia Busza
Department of Neurobiology and Program in Neuroscience, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
J Neurosci 27:10722-33. 2007..In conclusion, the behavioral responses to temperature input are determined by both the individual properties of specific groups of circadian neurons and their organization in a neural network... 
Light and temperature control the contribution of specific DN1 neurons to Drosophila circadian behaviorYong Zhang
Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA
Curr Biol 20:600-5. 2010..Thus, the Clk4.1M-GAL4-positive DN1s, or the neurons they target, integrate light and temperature inputs to control locomotor rhythms. Our study therefore reveals a novel mechanism contributing to the plasticity of circadian behavior...- A subset of dorsal neurons modulates circadian behavior and light responses in DrosophilaAlejandro Murad
Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
Neuron 53:689-701. 2007..Thus, a subset of Dorsal Neurons shares with the LNvs the ability to function as pacemakers for circadian behavior, and its importance is promoted by light... - A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponsesRaphaelle Dubruille
Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
PLoS Genet 5:e1000787. 2009..We therefore conclude that KIS is a key transcriptional regulator of genes that function in the CRY signaling cascade, and thus it plays an important role in the synchronization of circadian rhythms with the dayrationight cycle... - Cryptochromes define a novel circadian clock mechanism in monarch butterflies that may underlie sun compass navigationHaisun Zhu
Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
PLoS Biol 6:e4. 2008..Our data further suggest that CRY2 may have a dual role in the monarch butterfly's brain-as a core clock element and as an output that regulates circadian activity in the central complex, the likely site of the sun compass... - A plastic clock: how circadian rhythms respond to environmental cues in DrosophilaRaphaelle Dubruille
Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
Mol Neurobiol 38:129-45. 2008..Here, we review our current knowledge of the molecular and neural mechanisms contributing to the plasticity of Drosophila circadian rhythms, which are proving to be remarkably sophisticated and complex... - Somatic localization of a specific large-conductance calcium-activated potassium channel subtype controls compartmentalized ethanol sensitivity in the nucleus accumbensGilles Martin
Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
J Neurosci 24:6563-72. 2004..Finally, an EtOH concentration (50 mm) that increased BK channel open probability strongly decreased the duration of somatic-generated action potential in NAcc neurons... - RNase protection assayPatrick Emery
Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
Methods Mol Biol 362:343-8. 2007..Methods to generate the riboprobes and to perform the RNase protection assay itself are described in this chapter... - Mutagenesis with DrosophilaPatrick Emery
Department of Neurobiology, University of Massachusetts Medical School, Worcester, USA
Methods Mol Biol 362:187-95. 2007..An alkylating agent can be used to randomly alter the fly genome, or transposable elements can be mobilized to disrupt or increase the expression of the targeted genes. The advantages of these different methods are complementary... - A rhythmic RorPatrick Emery
Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, Massachusetts 01605, USA
Neuron 43:443-6. 2004..This finding defines the second feedback loop in mammals... - KAYAK-α modulates circadian transcriptional feedback loops in Drosophila pacemaker neuronsJinli Ling
Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA
J Neurosci 32:16959-70. 2012..We propose that the double role of KAY-α in the two transcriptional loops controlling Drosophila circadian behavior brings precision and stability to their oscillations... - Roles of the two Drosophila CRYPTOCHROME structural domains in circadian photoreceptionAnia Busza
Department of Neurobiology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, MA 01605, USA
Science 304:1503-6. 2004..This contrasts with the function of Arabidopsis CRY domains and demonstrates that insect and plant cryptochromes use different mechanisms... - PER-TIM interactions with the photoreceptor cryptochrome mediate circadian temperature responses in DrosophilaRachna Kaushik
Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts, United States of America
PLoS Biol 5:e146. 2007..The results indicate a role for CRY in circadian temperature as well as light regulation and suggest that these two features of the external 24-h cycle normally act together to dictate circadian phase... - Drosophila clock can generate ectopic circadian clocksJie Zhao
Howard Hughes Medical Institute, Department of Biology, Brandeis University, Waltham, MA 02454, USA
Cell 113:755-66. 2003..We propose that Clock is uniquely able to induce and organize the core elements of interdependent feedback loops necessary for circadian rhythms...