Research Topics
Genomes and Genes | C A ElmetsSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Host defense mechanisms in polyaromatic hydrocarbon carcinogenesisC A Elmets
Departmentof Dermatology, University of Alabama at Birmingham, Ala 35294 0009, USA
Skin Pharmacol Appl Skin Physiol 14:386-92. 2001..This may form the basis for novel immunopreventive strategies for individuals at high risk for development of tumors produced by PAHs...
Targeting ornithine decarboxylase for the prevention of nonmelanoma skin cancer in humansCraig A Elmets
Department of Dermatology, UAB Skin Diseases Research Center and UAB Comprehensive Cancer Center, The University of Alabama at Birmingham, 35294 0019, USA
Cancer Prev Res (Phila) 3:8-11. 2010..discusses our knowledge of the contribution of polyamines to BCC pathogenesis, how this knowledge advanced the development of a new method to prevent BCCs, and prospects for future studies of DFMO in BCC prevention...
An animal model of psoriasis in mice deficient in epidermal Jun proteinsCraig A Elmets
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294-0009, USA
Arch Dermatol 142:1499-500. 2006
Susceptibility to the biological effects of polyaromatic hydrocarbons is influenced by genes of the major histocompatibility complexC A Elmets
Department of Dermatology and the Skin Diseases Research Center, Case Western Reserve University, Cleveland, OH 44106, USA
Proc Natl Acad Sci U S A 95:14915-9. 1998..The observations are consistent with the hypothesis that cell-mediated immunity to chemical carcinogens serves to protect individuals by removing mutant cells before they can evolve into clinically apparent neoplasms...
Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trialCraig A Elmets
Department of Dermatology, 1530 3rd Ave South, EFH 414, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Natl Cancer Inst 102:1835-44. 2010....
Topical application of dimethylbenz[a]anthracene results in the generation of multiple melanocytic nevi in C3H/HeN miceCraig A Elmets
Department of Dermatology, The University of Alabama at Birmingham, Birmingham, AL 35294 0009, USA
Toxicol Appl Pharmacol 195:355-60. 2004....
Green tea polyphenols: DNA photodamage and photoimmunologyS K Katiyar
Department of Dermatology, School of Medicine, University of Alabama at Birmingham, 1670 University Blvd, VH501, Box 202, Birmingham, AL 35294, USA
J Photochem Photobiol B 65:109-14. 2001..These in vivo observations suggest that GTPs are photoprotective, and can be used as pharmacological agents for the prevention of solar UVB light-induced skin disorders associated with immune suppression and DNA damage...
Resveratrol enhances cell-mediated immune response to DMBA through TLR4 and prevents DMBA induced cutaneous carcinogenesisNabiha Yusuf
Department of Dermatology, Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, Alabama 35294 0019, USA
Mol Carcinog 48:713-23. 2009..The results of this study indicate that TLR4 is an important mediator of resveratrol chemoprevention in DMBA skin tumorigenesis...
(-)-Epigallocatechin-3-gallate prevents photocarcinogenesis in mice through interleukin-12-dependent DNA repairSyed M Meeran
Department of Dermatology, University of Alabama at Birmingham and Birmingham VA Medical Center, Birmingham, Alabama 35294, USA
Cancer Res 66:5512-20. 2006..Taken together, these results indicate for the first time that EGCG can prevent photocarcinogenesis through an EGCG-induced IL-12-dependent DNA repair mechanism...
Interleukin-12 deficiency is permissive for angiogenesis in UV radiation-induced skin tumorsSyed M Meeran
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1670 University Boulevard, Birmingham, AL 35294, USA
Cancer Res 67:3785-93. 2007....
T4 endonuclease V: review and application to dermatologyJennifer A Cafardi
University of Alabama at Birmingham, Department of Dermatology, USA
Expert Opin Biol Ther 8:829-38. 2008..When packaged in liposomes and applied topically, T4 endonuclease V can traverse the stratum corneum and become incorporated within the cytoplasm and nucleus of epidermal keratinocytes and Langerhans cells...
Silymarin inhibits UV radiation-induced immunosuppression through augmentation of interleukin-12 in miceSyed M Meeran
Department of Dermatology, University of Alabama at Birmingham, 1670 University Boulevard, Volker Hall 557, P.O. Box 202, Birmingham, AL 35294, USA
Mol Cancer Ther 5:1660-8. 2006..These data indicate for the first time that silymarin has the ability to protect mice from UVB-induced immunosuppression and that this protective effect is mediated, at least in part, through IL-12...
Green tea polyphenolic antioxidants and skin photoprotection (Review)S K Katiyar
Department of Dermatology, School of Medicine, University of Alabama at Birmingham, VH 501B, Birmingham, AL 35294, USA
Int J Oncol 18:1307-13. 2001..Therefore, the focus of this communication is to review and analyze the photoprotective effects of green tea polyphenols to skin...
Orally administered green tea polyphenols prevent ultraviolet radiation-induced skin cancer in mice through activation of cytotoxic T cells and inhibition of angiogenesis in tumorsSudheer K Mantena
Department of Dermatology, University of Alabama at Birmingham, AL, USA
J Nutr 135:2871-7. 2005....
Mass spectrometric proteomics profiles of in vivo tumor secretomes: capillary ultrafiltration sampling of regressive tumor massesChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
Proteomics 6:6107-16. 2006..The technique involving CUF probes linked to mass spectrometric proteomics reinforces systems biology studies of cell-cell interactions and is potentially applicable to the discovery of in vivo biomarkers in human disease...
Phthalocyanine photodynamic therapy: disparate effects of pharmacologic inhibitors on cutaneous photosensitivity and on tumor regressionC Anderson
Department of Dermatology, Case Western Reserve University, Cleveland, OH, USA
Photochem Photobiol 65:895-901. 1997..The findings suggest that it should be possible to devise PDT protocols that block cutaneous photosensitivity without impairing the anti-tumor response to the agents...
Surfactant sodium lauryl sulfate enhances skin vaccination: molecular characterization via a novel technique using ultrafiltration capillaries and mass spectrometric proteomicsChun Ming Huang
Department of Dermatology, Skin Diseases Research Center, University of Alabama, Birmingham, Alabama 35294, USA
Mol Cell Proteomics 5:523-32. 2006..Two secretory proteins, named as calcium-binding protein S100A9 and thymosin beta4, were identified by this novel technique. These two proteins thus may provide new insight into the enhancing effect of surfactants on skin vaccination...
CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responsesDonggou He
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Immunol 177:6852-8. 2006..This indicates that CD8+ IL-17-producing cells are distinct from Tc1 cells and are important in effector functions at the elicitation of CHS. These studies provide insights into a novel mechanism for CHS...
Photoprotective effects of green tea polyphenolsNabiha Yusuf
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Photodermatol Photoimmunol Photomed 23:48-56. 2007..Green tea polyphenols thus have the potential, when used in conjunction with traditional sunscreens, to further protect the skin against the adverse effects of ultraviolet radiation...
In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass spectrometric proteomicsChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
Proteomics 6:5805-14. 2006..The technique of using CUF probes linked to mass spectrometric proteomics represents a powerful method to identify in vivo secreted proteins, and may be applicable for identification of proteins relevant in various human diseases...
Green tea and skin cancer: photoimmunology, angiogenesis and DNA repairSuchitra Katiyar
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Nutr Biochem 18:287-96. 2007..New mechanistic information strongly supports and explains the chemopreventive activity of GTPs against photocarcinogenesis...
CD4 T cell-induced, bid-dependent apoptosis of cutaneous dendritic cells regulates T cell expansion and immune responsesSanjay Pradhan
Department of Dermatology, University of Alabama at Birmingham, 1670 University Boulevard, VH 509 Birmingham, AL 35294, USA
J Immunol 177:5956-67. 2006..Thus, enhanced Ag presentation function was intrinsic to Bid KO cDCs. Therefore, Bid is an important regulator of LC viability and Ag presentation function...
Acquired and innate immunity to polyaromatic hydrocarbonsNabiha Yusuf
Department of Dermatology, University of Alabama at Birmingham, 1530 Third Avenue South, Birmingham, AL, USA
Toxicol Appl Pharmacol 224:308-12. 2007..Efforts to augment immune responses to the chemicals that cause tumors may be a productive approach to the prevention of tumors caused by these agents...
Osteopontin expression in normal skin and non-melanoma skin tumorsPi Ling Chang
Department of Nutrition Sciences, 311 Susan Mott Webb Nutrition Sciences Building, 1675 University Boulevard, University of Alabama at Birmingham, Birmingham, Alabama 35295 3360, USA
J Histochem Cytochem 56:57-66. 2008..In conclusion, these data suggest that OPN is associated with keratinocyte differentiation and that it is expressed in AK and SCC, which have metastatic potential, but minimally expressed in solid BCC...
Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesisNabiha Yusuf
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, 1670 University Boulevard, VH 566A, P O Box 202, Birmingham, AL 35294 0019, USA
Cancer Res 68:615-22. 2008..Efforts to divert the cell-mediated immune response from one that is IL-17 mediated to one that is IFN-gamma mediated may prove to be beneficial in the prevention of DMBA-induced cutaneous tumors...
DNA damage, apoptosis and langerhans cells--Activators of UV-induced immune toleranceLaura Timares
Department of Dermatology, The UAB Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
Photochem Photobiol 84:422-36. 2008....
Antagonistic roles of CD4+ and CD8+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesisNabiha Yusuf
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham and Birmingham VA Medical Center, Birmingham, Alabama, USA
Cancer Res 68:3924-30. 2008..Manipulation of T-cell subpopulations that are induced by carcinogenic chemicals, like DMBA, could be a means of preventing skin cancers caused by these agents...
Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivityNabiha Yusuf
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Immunol 182:675-83. 2009..The results suggest that HSPs form a link between adaptive and innate immunity during the early stages of contact hypersensitivity...
IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cellsDonggou He
Department of Dermatology, University of Alabama, Birmingham, AL 35294, USA
J Immunol 184:2281-8. 2010..The study provides novel insights into the role of IL-17 in tumor development and has major implications for targeting IL-17 in treatment of tumors...
Prospective highlights of functional skin proteomicsChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Mass Spectrom Rev 24:647-60. 2005..This type of research into functional skin proteomics will provide a critical step toward understanding disease and developing successful therapeutic strategies...
Green tea polyphenols prevent ultraviolet light-induced oxidative damage and matrix metalloproteinases expression in mouse skinPraveen K Vayalil
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
J Invest Dermatol 122:1480-7. 2004..These data suggest that GTP as a dietary supplement could be useful to attenuate solar UVB light-induced premature skin aging...
A differential proteome in tumors suppressed by an adenovirus-based skin patch vaccine encoding human carcinoembryonic antigenChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, VH 501, 1670 University Blvd, Birmingham, AL 35294 0019, USA
Proteomics 5:1013-23. 2005..These proteins may provide a vital link between early-stage tumor suppression and immune response of skin patch vaccination...
IL-17 and IFN-gamma mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responsesDonggou He
Department of Dermatology, University of Alabama, Birmingham, Alabama 35294, USA
J Immunol 183:1463-70. 2009..This outcome improves understanding of pathogenesis and provides new insights into therapeutic strategies for CHS...
Proteomics reveals that proteins expressed during the early stage of Bacillus anthracis infection are potential targets for the development of vaccines and drugsChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, Alabama, USA
Genomics Proteomics Bioinformatics 2:143-51. 2004....
Comparative proteomic profiling of murine skinChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, USA
J Invest Dermatol 121:51-64. 2003..These data establish numerous reference markers within the proteome map of murine skin and provide an important framework for future efforts aimed at characterization of the epidermal and subepidermal responses to environmental changes...
Proteomic characterization of skin and epidermis in response to environmental agentsChun Ming Huang
Department of Dermatology, Skin Diseases Research Center, University of Alabama, Birmingham, AL 35294 0019, USA
Expert Rev Proteomics 2:809-20. 2005....
In vivo protein sampling using capillary ultrafiltration semi-permeable hollow fiber and protein identification via mass spectrometry-based proteomicsChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, VH 566A, 1670 University Blvd, Birmingham, AL 35294 0019, USA
J Chromatogr A 1109:144-51. 2006..Also, the technique represents a powerful method for the identification of in vivo secreted proteins and has potential application for in the detection of biomarkers for human diseases...
Identification of Bacillus anthracis proteins associated with germination and early outgrowth by proteomic profiling of anthrax sporesChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, 35294 0019, USA
Proteomics 4:2653-61. 2004..The 31 new proteins identified in this study also complement an emerging proteomic database of B. anthracis...
Phthalocyanine 4 (Pc 4) photodynamic therapy of human OVCAR-3 tumor xenograftsV C Colussi
Department of Dermatology, Case Western Reserve University, Cleveland, OH 44106 5028, USA
Photochem Photobiol 69:236-41. 1999..Early apoptosis, as revealed by PARP cleavage, DNA fragmentation and p21 overexpression, may be responsible for the excellent Pc 4-PDT response. Clinical trials of Pc 4-PDT are warranted...
In situ changes in the relative abundance of human epidermal cytokine messenger RNA levels following exposure to the poison ivy/oak contact allergen urushiolK D Boehm
Department of Dermatology, Case Western Reserve University, Cleveland, Ohio, USA
Exp Dermatol 5:150-60. 1996..The data provide evidence for an in vivo role for epidermal IL-1 alpha, IL-1 beta and TNF-alpha transcription in the regulation of IL-1 beta and TNF-alpha polypeptide levels in the epidermis in response to this common contact allergen...
Inhibition of the high affinity Fc receptor (Fc gamma RI) on human monocytes by porphyrin photosensitization is highly specific and mediated by the generation of superoxide radicalsJ Krutmann
Department of Dermatology, Case Western Reserve University, Cleveland, Ohio 44106
J Biol Chem 264:11407-13. 1989..These studies identify porphyrin photosensitization as a unique mechanism by which to selectively down-regulate Fc gamma RI-mediated functions...
A critical role for the proapoptotic protein bid in ultraviolet-induced immune suppression and cutaneous apoptosisSanjay Pradhan
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Immunol 181:3077-88. 2008..These studies provide evidence that Bid activation is a critical upstream mediator in UV-induced keratinocyte and LC apoptosis and that its absence abrogates UV-induced immune tolerance...
CD11b+ cells are the major source of oxidative stress in UV radiation-irradiated skin: possible role in photoaging and photocarcinogenesisAnshu Mittal
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Photochem Photobiol 77:259-64. 2003....
IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammationSom D Sharma
Department of Dermatology, University of Alabama at Birmingham, 1670 University Boulevard, Volker Hall 557, Birmingham, AL 35294, USA
Carcinogenesis 30:1970-7. 2009..In the case of DMBA/TPA-induced skin tumor development, the endogenous IL-12 modulates the tumor promoter stimulation of inflammatory responses...
Treatment of green tea polyphenols in hydrophilic cream prevents UVB-induced oxidation of lipids and proteins, depletion of antioxidant enzymes and phosphorylation of MAPK proteins in SKH-1 hairless mouse skinPraveen K Vayalil
Department of Dermatology, University of Alabama at Birmingham, 1670 University Blvd, Volker Hall 557, 35294, USA
Carcinogenesis 24:927-36. 2003....
Interleukin-12-deficient mice are at greater risk of UV radiation-induced skin tumors and malignant transformation of papillomas to carcinomasSyed M Meeran
Department of Dermatology, University of Alabama at Birmingham, 1670 University Boulevard, Volker Hall 557, P O Box 202, Birmingham, AL 35294, USA
Mol Cancer Ther 5:825-32. 2006..Taken together, our data show that IL-12 deficiency is associated with the greater risk of photocarcinogenesis in mice, and this may be due to reduction in damaged DNA repair ability...
Cutaneous photoprotection from ultraviolet injury by green tea polyphenolsC A Elmets
Department of Dermatology, Case Western Reserve, Cleveland, Ohio, USA
J Am Acad Dermatol 44:425-32. 2001..CONCLUSION: Polyphenolic extracts of green tea are effective chemopreventive agents for many of the adverse effects of sunlight on human health and may thus serve as natural alternatives for photoprotection...
The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph nodeH Xu
Department of Dermatology, University of Alabama at Birmingham, Birmingham 35294, USA
Eur J Immunol 31:3085-93. 2001..This study indicates that ICAM-1 regulates the migration of dendritic cells into regional lymph nodes but not into or out of the skin...
Slit2 inhibits growth and metastasis of fibrosarcoma and squamous cell carcinomaHee Kyung Kim
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Neoplasia 10:1411-20. 2008....
The other end of the rainbow: infrared and skinAton M Holzer
Department of Dermatology, University of Alabama at Birmingham, 1530 3rd Avenue S, Birmingham, AL 35294, USA
J Invest Dermatol 130:1496-9. 2010..Their work paves the way for new research directions in IRA photobiology and raises important clinical questions regarding photoprotection and IRR-based dermatotherapy...
The immunosuppressive effects of phthalocyanine photodynamic therapy in mice are mediated by CD4+ and CD8+ T cells and can be adoptively transferred to naive recipientsNabiha Yusuf
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, AL, USA
Photochem Photobiol 84:366-70. 2008..Procedures that limit PDT-induced immunosuppression but do not affect PDT-induced regression of tumors may prove superior to PDT alone in promoting long-term antitumor responses...
Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: relationship to decreased fat and lipid peroxidationAnshu Mittal
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Carcinogenesis 24:1379-88. 2003..Together, it can be suggested that inhibition of photocarcinogenesis by GSP treatment may be associated with the reduction in UVB-induced oxidative damage and tissue fat content...
A phase III, randomized, double-blind, placebo-controlled study of peldesine (BCX-34) cream as topical therapy for cutaneous T-cell lymphomaM Duvic
Department of Dermatology, University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA
J Am Acad Dermatol 44:940-7. 2001..Whether the vehicle cream has more than a placebo therapeutic effect is unclear. The relatively high (24%) placebo response rate should be kept in mind in assessing other treatments for early-stage CTCL...
Visualizing CD4 T-cell migration into inflamed skin and its inhibition by CCR4/CCR10 blockades using in vivo imaging modelX Wang
Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Br J Dermatol 162:487-96. 2010..Chemokines are critical mediators of T-cell homing into inflamed skin. The complex nature of this multicellular response makes it difficult to analyse mechanisms mediating the early responses in vivo...
Utilization of narrow-band ultraviolet light B therapy and etanercept for the treatment of psoriasis (UNITE): efficacy, safety, and patient-reported outcomesLeon Kircik
Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA
J Drugs Dermatol 7:245-53. 2008..Etanercept and narrow-band ultraviolet light B (NB-UVB) are widely used to treat this disease...
Grape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathwaysAnshu M Roy
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Neoplasia 7:24-36. 2005..These data clearly demonstrate that GSP-induced apoptosis is p53-dependent and mediated through the Bcl-2, Bax, and caspase 3 pathways...
A new method to test the effectiveness of sunscreen ingredients in a novel nano-surface skin cell mimicRajagopal Krishnan
Department of Physics, University of Alabama at Birmingham, Birmingham, AL, USA
Photochem Photobiol 82:1549-56. 2006..The new method also allows the simultaneous evaluation of a host of photophysical properties of sunscreening chemicals...
Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humansKent R Van Kampen
Vaxin Inc, VH-501, 1670 University Blvd, Birmingham, AL 35294, USA
Vaccine 23:1029-36. 2005..These results provide the foundation for further human testing of needleless vectored vaccines as promising alternatives to current vaccines...
Targeting wild-type and mutant p53 with small molecule CP-31398 blocks the growth of rhabdomyosarcoma by inducing reactive oxygen species-dependent apoptosisJianmin Xu
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0019, USA
Cancer Res 70:6566-76. 2010..Our findings indicate that the ability of CP-31398 to modulate wild-type and mutant p53 results in the inhibition of RMS growth and invasiveness...
The safety and efficacy of high-dose alefacept compared with a loading dose of alefacept in patients with chronic plaque psoriasisJennifer A Cafardi
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
Skinmed 7:67-72. 2008..Two separate dosing regimens are evaluated in this study: 30 mg IM for 6 weeks followed by 15 mg IM for 6 weeks (group 1) and alefacept 30 mg IM weekly for 12 weeks (group 2)...
Fluorescence of sunscreens adsorbed to dielectric nanospheres: parallels to optical behavior on hacat cells and skinRajagopal Krishnan
Department of Physics, University of Alabama at Birmingham, USA
Photochem Photobiol 82:1557-65. 2006..An unexpected result of this comparative study was the observation of an increase in a specific skin component emission caused by addition of padimate O...
Quantitative proteomes and in vivo secretomes of progressive and regressive UV-induced fibrosarcoma tumor cells: mimicking tumor microenvironment using a dermis-based cell-trapped system linked to tissue chamberYang Shi
Burnham Institute for Medical Research, La Jolla, CA, USA
Proteomics 7:4589-600. 2007..Differential tumor proteomes and in vivo secretome were thus accentuated as potential therapeutic targets to control tumor growth...
Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologicsAlan Menter
Baylor University Medical Center, Dallas, Texas, USA
J Am Acad Dermatol 58:826-50. 2008..Finally, we will discuss the safety and efficacy of the biologic treatments used to treat patients with psoriasis...
Research Grants
- Training in Investigative DermatologyCraig Elmets; Fiscal Year: 2007..The ultimate goal of this program will be to provide superior training for the next generation of academic researchers in investigative dermatology. ..
- PHTHALOCYANINE PDT--IN VIVO RESPONSES AND MECHANISMSCraig Elmets; Fiscal Year: 2004..The long-term goal of these studies is to generate new knowledge regarding the in vivo mechanisms by which PDT works so that it can be used more effectively to treat cancer. ..
- IMMUNODERMATOLOGICAL THERAPY OF SKIN CANCERCraig Elmets; Fiscal Year: 2003..The ultimate goal of this proposal is to generate new knowledge that can be used to develop new and better strategies for the control of non-melanoma and melanoma skin cancer. ..
