Roman A Eliseev

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Role of cyclophilin D in the resistance of brain mitochondria to the permeability transition
    Roman A Eliseev
    Musculoskeletal Research Center, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States roman
    Neurobiol Aging 28:1532-42. 2007
  2. pmc Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect
    Roman A Eliseev
    Center for Musculoskeletal Research and Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 284:9692-9. 2009
  3. ncbi Calcium and mitochondria
    Thomas E Gunter
    Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, 575 Elmwood Avenue, Rochester, NY 14642, USA
    FEBS Lett 567:96-102. 2004
  4. pmc Mitochondrial dysfunction in cancer cells due to aberrant mitochondrial replication
    Yuriy Shapovalov
    The Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 286:22331-8. 2011
  5. pmc Targeting radioresistant osteosarcoma cells with parthenolide
    Daniel Zuch
    Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, 575 Elmwood Ave, Rochester, New York 14642, USA
    J Cell Biochem 113:1282-91. 2012
  6. ncbi Bcl-2 prevents abnormal mitochondrial proliferation during etoposide-induced apoptosis
    Roman A Eliseev
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Exp Cell Res 289:275-81. 2003
  7. ncbi Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB
    Roman A Eliseev
    Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA
    Exp Cell Res 312:40-50. 2006
  8. doi Proteasome inhibition with bortezomib suppresses growth and induces apoptosis in osteosarcoma
    Yuriy Shapovalov
    Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Int J Cancer 127:67-76. 2010
  9. ncbi Bcl-2 and tBid proteins counter-regulate mitochondrial potassium transport
    Roman A Eliseev
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Biochim Biophys Acta 1604:1-5. 2003
  10. ncbi Diazoxide-mediated preconditioning against apoptosis involves activation of cAMP-response element-binding protein (CREB) and NFkappaB
    Roman A Eliseev
    Musculo Skeletal Research Unit, University of Rochester School of Medicine, Rochester, New York 14642, USA
    J Biol Chem 279:46748-54. 2004

Collaborators

Detail Information

Publications11

  1. ncbi Role of cyclophilin D in the resistance of brain mitochondria to the permeability transition
    Roman A Eliseev
    Musculoskeletal Research Center, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States roman
    Neurobiol Aging 28:1532-42. 2007
    ..This may be a protection mechanism that raises the threshold of brain tissue against injuries...
  2. pmc Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect
    Roman A Eliseev
    Center for Musculoskeletal Research and Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 284:9692-9. 2009
    ..The fact that some tumors overexpress CypD suggests that this may be an additional mechanism of suppression of apoptosis in cancer...
  3. ncbi Calcium and mitochondria
    Thomas E Gunter
    Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, 575 Elmwood Avenue, Rochester, NY 14642, USA
    FEBS Lett 567:96-102. 2004
    ..STKE re1 (2004) 1-9], may also influence this story...
  4. pmc Mitochondrial dysfunction in cancer cells due to aberrant mitochondrial replication
    Yuriy Shapovalov
    The Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Biol Chem 286:22331-8. 2011
    ..Our study provides insight into mechanisms of mitochondrial dysfunction in cancer and may offer potential therapeutic targets...
  5. pmc Targeting radioresistant osteosarcoma cells with parthenolide
    Daniel Zuch
    Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, 575 Elmwood Ave, Rochester, New York 14642, USA
    J Cell Biochem 113:1282-91. 2012
    ..Therefore, as a supplement to current multimodal therapy, parthenolide may sensitize osteosarcoma tumors to radiation and greatly reduce the prevalence of relapse and metastatic progression...
  6. ncbi Bcl-2 prevents abnormal mitochondrial proliferation during etoposide-induced apoptosis
    Roman A Eliseev
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Exp Cell Res 289:275-81. 2003
    ..Our data suggest that proliferation of mitochondria may be an integral part of a cascade of apoptotic events...
  7. ncbi Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB
    Roman A Eliseev
    Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA
    Exp Cell Res 312:40-50. 2006
    ..We therefore conclude that in osteosarcoma Saos2 cells, NFkappaB represses BMP/Smad signaling and BMP2-induced differentiation through Smad7...
  8. doi Proteasome inhibition with bortezomib suppresses growth and induces apoptosis in osteosarcoma
    Yuriy Shapovalov
    Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Int J Cancer 127:67-76. 2010
    ..Published 2009 UICC. This article is a US Government work and, as such, is in the public domain in the United States of America...
  9. ncbi Bcl-2 and tBid proteins counter-regulate mitochondrial potassium transport
    Roman A Eliseev
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Biochim Biophys Acta 1604:1-5. 2003
    ..The described counter-regulation of mitochondrial potassium transport by bcl-2 and Bid suggests a novel view of a mechanism of cytochrome c release from mitochondria in apoptosis...
  10. ncbi Diazoxide-mediated preconditioning against apoptosis involves activation of cAMP-response element-binding protein (CREB) and NFkappaB
    Roman A Eliseev
    Musculo Skeletal Research Unit, University of Rochester School of Medicine, Rochester, New York 14642, USA
    J Biol Chem 279:46748-54. 2004
    ..We, therefore, conclude that diazoxide-mediated preconditioning against apoptosis involves activation of the pro-survival transcription factors CREB and NFkappaB...
  11. ncbi Increased radiation-induced apoptosis of Saos2 cells via inhibition of NFkappaB: a role for c-Jun N-terminal kinase
    Roman A Eliseev
    Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Cell Biochem 96:1262-73. 2005
    ..Our study brings new insight into the mechanisms underlying radiation-induced apoptosis of osteosarcoma, and may lead to development of new therapeutic strategies against osteosarcoma...