Research Topics
| M Tarek ElghetanySummaryAffiliation: University of Texas Medical Branch Country: USA Publications
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Detail Information
Publications
CD87 as a marker for terminal granulocytic maturation: assessment of its expression during granulopoiesisM Tarek Elghetany
Division of Hematopathology, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA
Cytometry B Clin Cytom 51:9-13. 2003..Surface expression of this antigen has not been adequately studied on bone marrow granulocytes, and the small number of previous studies has provided conflicting data...
p53 protein overexpression in bone marrow biopsies of patients with Shwachman-Diamond syndrome has a prevalence similar to that of patients with refractory anemiaM Tarek Elghetany
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0743, USA
Arch Pathol Lab Med 126:452-5. 2002..This similarity was further investigated for p53 protein overexpression using archived tissue from patients with hematologic diseases having various leukemic propensities, including SDS and refractory anemia...
Surface antigen changes during normal neutrophilic development: a critical reviewM Tarek Elghetany
Division of Hematopathology, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0743, USA
Blood Cells Mol Dis 28:260-74. 2002..This article reviews the alterations in surface antigen expression during normal neutrophilic granulopoiesis...
Flow cytometric study of neutrophilic granulopoiesis in normal bone marrow using an expanded panel of antibodies: correlation with morphologic assessmentsM Tarek Elghetany
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0743, USA
J Clin Lab Anal 18:36-41. 2004..A successful strategy for detecting maturation defects is to include several antibodies that are known to be expressed or absent at the same stage of maturation, such as CD16, CD35, CD64, and CD87...
Myelodysplastic syndromes in children: a critical review of issues in the diagnosis and classification of 887 cases from 13 published seriesM Tarek Elghetany
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0743, USA
Arch Pathol Lab Med 131:1110-6. 2007..The classification of pediatric MDSs has undergone significant evolution in the past 20 years...
Physiologic variations in granulocytic surface antigen expression: impact of age, gender, pregnancy, race, and stressM Tarek Elghetany
University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 0743, USA
J Leukoc Biol 75:157-62. 2004..Stress also has an impact on some surface markers, particularly adhesion molecules, such as CD62L and CD54. These factors need to be taken in consideration for the optimal interpretation of granulocytic surface marker studies...
Impact of preanalytical variables on granulocytic surface antigen expression: a reviewM Tarek Elghetany
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0743, USA
Cytometry B Clin Cytom 65:1-5. 2005..Despite the increased use of flow cytometry to study granulocytes, there seems to be no well-established standards regarding specimen handling for these studies...
The left shift: are there granulocytic surface markers that are better indicators?M Tarek Elghetany
Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
Lab Hematol 10:169-71. 2004
Assessment of CD24 expression on bone marrow neutrophilic granulocytes: CD24 is a marker for the myelocytic stage of developmentM Tarek Elghetany
Division of Hematopathology, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0743, USA melghetautmb edu
Am J Hematol 71:348-9. 2002..We conclude that CD24 is expressed on the neutrophilic granulocytes at the stage of myelocytes, and hence it could potentially be used to study normal and abnormal maturation of granulocytes...
Expression of CD4 on peripheral blood granulocytes. a novel finding in a case of myelodysplastic syndrome in association with t(5;12)M Tarek Elghetany
Department of Pathology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, USA
Cancer Genet Cytogenet 136:38-42. 2002..Since the breakpoint on chromosome 12 is near the CD4 gene, which is mapped to 12p12, we hypothesize that dysregulation of the CD4 gene may have occurred resulting in its persistent expression on mature and maturing granulocytes...
Use of error grid analysis to evaluate acceptability of a point of care prothrombin time meterJohn R Petersen
University of Texas Medical Branch, Galveston, Texas 77555 0551, United States
Clin Chim Acta 411:131-4. 2010..We showed how error grid (EG) analysis can be used to evaluate POCT PT INR with the CL...
CD36: a multiligand moleculeYimin Ge
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA
Lab Hematol 11:31-7. 2005..The future challenge will be to further understand the mechanisms by which CD36 affects these diverse functions and to design therapeutic strategies that can alter the course of the diseases...
Urokinase plasminogen activator receptor (CD87): something old, something newYimin Ge
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0743, USA
Lab Hematol 9:67-71. 2003..Therapeutic strategies targeting CD87 as a key molecule of tumor invasion and metastasis have great potential for becoming valuable assets in therapy for malignant tumors...
Marginal zone variant of mantle cell lymphoma: CD5-negative cyclin D1-positive variant posing a diagnostic dilemmaNatalia Golardi
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0743, USA
Pathol Int 59:317-21. 2009..Differentiating MCL from MZL has prognostic and therapeutic implications, particularly when considering the potential role of targeted therapy and cell cycle modulators...
Diagnostic utility of flow cytometric immunophenotyping in myelodysplastic syndromeM Tarek Elghetany
Blood 99:391-2. 2002
The CCC system: is it really the answer to pediatric MDS?Blanche P Alter
J Pediatr Hematol Oncol 25:426-7; author reply 427-8. 2003
Shwachman-Diamond syndrome: report from an international conferenceRobert Rothbaum
St Louis Children's Hospital, St Louis, Missouri, USA
J Pediatr 141:266-70. 2002
