Affiliation: University of Wisconsin
- Exercise-induced intrapulmonary arteriovenous shunting in healthy humansMarlowe W Eldridge
John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin, Medical School, Madison, Wisconsin 53792 4108, USA
J Appl Physiol 97:797-805. 2004..They may also act as a protective parallel vascular network limiting the rise in regional pulmonary vascular pressure while preserving cardiac output during exercise...
- Effects of altitude and exercise on pulmonary capillary integrity: evidence for subclinical high-altitude pulmonary edemaMarlowe W Eldridge
John Rankin Laboratory of Pulmonary Medicine, Department of Pediatrics, Univ of Wisconsin, Medical School, H4 422 Clinical Sciences Center, 600 Highland Ave, Madison, WI 53792 4108, USA
J Appl Physiol 100:972-80. 2006..These findings suggest that pulmonary capillary disruption occurs with intense exercise in healthy humans and that hypoxia augments the mechanical stresses on the pulmonary microcirculation...
- Exercise-induced arterial hypoxemia: consequences for locomotor muscle fatigueLee M Romer
John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin Madison, USA
Adv Exp Med Biol 588:47-55. 2006..These effects of EIAH were confirmed in mild environmental hypoxia (FIO2 .17, SaO2 88%) which significantly augmented the magnitude of exercise-induced quadriceps fatigue observed in normoxia...
- Direct demonstration of 25- and 50-microm arteriovenous pathways in healthy human and baboon lungsAndrew T Lovering
John Rankin Laboratory of Pulmonary Medicine, Univ of Wisconsin School of Medicine and Public Health, Madison, WI 53706 1532, USA
Am J Physiol Heart Circ Physiol 292:H1777-81. 2007....
- Shear stress paradigm for perinatal fractal arterial network remodeling in lambs with pulmonary hypertension and increased pulmonary blood flowZahra Ghorishi
Department of Pediatrics, University of California, Davis, CA 95616, USA
Am J Physiol Heart Circ Physiol 292:H3006-18. 2007....
- Excessive gas exchange impairment during exercise in a subject with a history of bronchopulmonary dysplasia and high altitude pulmonary edemaAndrew T Lovering
University of Wisconsin School of Medicine and Public Health, Department of Population Health Sciences, John Rankin Laboratory of Pulmonary Medicine, Madison, Wisconsin 53706 1532, USA
High Alt Med Biol 8:62-7. 2007....
- Treatment of airway inflammation improves exercise pulmonary gas exchange and performance in asthmatic subjectsHans C Haverkamp
Department of Medicine, University of Vermont, Vermont Lung Center, Burlington, VT 05405, USA
J Allergy Clin Immunol 120:39-47. 2007..Asthma is an inflammatory disease of the airways that can lead to impaired arterial blood oxygenation during exercise...
- Exercise-induced arteriovenous intrapulmonary shunting in dogsMichael K Stickland
John Rankin Laboratory of Pulmonary Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
Am J Respir Crit Care Med 176:300-5. 2007....
- Intrapulmonary shunting and pulmonary gas exchange during normoxic and hypoxic exercise in healthy humansAndrew T Lovering
Department of Human Physiology, 1240 University of Oregon, Eugene, OR 97403 1240, USA
J Appl Physiol 104:1418-25. 2008..Whether oxygen tension specifically regulates these novel pathways or opens them indirectly via effects on the conventional pulmonary vasculature remains unclear...
- Update in the understanding of respiratory limitations to exercise performance in fit, active adultsJerome A Dempsey
University of Wisconsin Madison, 1300 University Avenue, Madison, WI 53706, USA
Chest 134:613-22. 2008..Exercise in the hypoxic environments of even moderately high altitudes will greatly exacerbate the negative influences of these respiratory system limitations to exercise performance, especially in highly fit individuals...
- Intrapulmonary shunt during normoxic and hypoxic exercise in healthy humansAndrew T Lovering
The John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin Madison, Wisconsin, USA
Adv Exp Med Biol 588:31-45. 2006..Future work will better define the conditions for shunt recruitment as well as their physiologic consequence...
- Arterial oxygenation influences central motor output and exercise performance via effects on peripheral locomotor muscle fatigue in humansMarkus Amann
The John Rankin Laboratory of Pulmonary Medicine, 4245 Medical Science Center, 1300 University Avenue, Madison, WI 53706, USA
J Physiol 575:937-52. 2006....
- L-arginine supplementation enhances exhaled NO, breath condensate VEGF, and headache at 4,342 mJim K Mansoor
University of the Pacific, Stockton, CA, USA
High Alt Med Biol 6:289-300. 2005..In total, our observations indicate that L-arginine supplementation is not beneficial in the prophylactic treatment of AMS...
- Responses and limitations of the respiratory system to exerciseAndrew T Lovering
The John Rankin Laboratory of Pulmonary Medicine, Department of Population Health Sciences, University of Wisconsin at Madison, Madison, WI 53706 1532, USA
Clin Chest Med 26:439-57, vi. 2005..Nonetheless, there are several exceptional cases in which the lung is unable to accommodate the demands of exercise because of vascular or airway limitations...
- Respiratory health and indoor air pollution at high elevationJacky Ann Rosati
Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, USA
Arch Environ Occup Health 60:96-105. 2005..It appears that augmented lung mechanics of this high-altitude population are adaptive to reduce the work of breathing; thus, decrements in lung function go undetected because the true predicted values are greater than expected...
- Contrast ultrasound techniques in the detection and quantification of patent foramen ovale: myth versus reality--a clarificationAndrew T Lovering
Stroke 36:1109. 2005
- Effect of inhaled endotoxin on airway and circulating inflammatory cell phagocytosis and CD11b expression in atopic asthmatic subjectsNeil E Alexis
Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, 27599, USA
J Allergy Clin Immunol 112:353-61. 2003..Macrophage and neutrophil functions have been reported to be modified by endotoxin in vitro and in vivo, and response to endotoxin is mediated largely by airway phagocytes and related to allergic inflammation...
- Comprehensive Characterization of Intrapulmonary Arteriovenous Pathways in HealthMarlowe Eldridge; Fiscal Year: 2010..The goal of this proposal is to better define the function regulation and consequences of these newly identified lung blood vessels in health and disease. ..