A C Elder

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Translocation and effects of ultrafine particles outside of the lung
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, NY 14642, USA
    Clin Occup Environ Med 5:785-96. 2006
  2. ncbi Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, NY, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:434-50. 2009
  3. ncbi Translocation of inhaled ultrafine manganese oxide particles to the central nervous system
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Environ Health Perspect 114:1172-8. 2006
  4. ncbi Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology
    Alison Elder
    Department of Environmental Medicine, University of Rochester, NY 14642, USA
    Toxicol Sci 88:614-29. 2005
  5. ncbi Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate
    A Elder
    Department of Environmental Medicine, University of Rochester, New York 14642, USA
    Exp Lung Res 31:527-46. 2005
  6. ncbi On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats
    Alison Elder
    Department of Environmental Medicine, University of Rochester, New York 14642, USA
    Inhal Toxicol 16:41-53. 2004
  7. ncbi Systemic effects of inhaled ultrafine particles in two compromised, aged rat strains
    Alison C P Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Inhal Toxicol 16:461-71. 2004
  8. ncbi Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate
    A C P Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Exp Lung Res 30:105-20. 2004
  9. ncbi Pulmonary inflammatory response to inhaled ultrafine particles is modified by age, ozone exposure, and bacterial toxin
    A C Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York, USA
    Inhal Toxicol 12:227-46. 2000
  10. ncbi Induction of adaptation to inhaled lipopolysaccharide in young and old rats and mice
    A C Elder
    Department of Environmental Medicine, University of Rochester, 575 Elmwood Ave, Box EHSC, Rochester, NY 14642, USA
    Inhal Toxicol 12:225-43. 2000

Detail Information

Publications11

  1. ncbi Translocation and effects of ultrafine particles outside of the lung
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, NY 14642, USA
    Clin Occup Environ Med 5:785-96. 2006
    ..These translocation processes are explored here as well potential consequences that result from exposure of extrapulmonary organs to inhaled ultrafine particles...
  2. ncbi Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, NY, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:434-50. 2009
    ....
  3. ncbi Translocation of inhaled ultrafine manganese oxide particles to the central nervous system
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Environ Health Perspect 114:1172-8. 2006
    ..Studies in monkeys with intranasally instilled gold ultrafine particles (UFPs; <100 nm) and in rats with inhaled carbon UFPs suggested that solid UFPs deposited in the nose travel along the olfactory nerve to the olfactory bulb...
  4. ncbi Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology
    Alison Elder
    Department of Environmental Medicine, University of Rochester, NY 14642, USA
    Toxicol Sci 88:614-29. 2005
    ..From these results, a subchronic NOAEL of 1 mg/m(3) respirable HSCb (Printex 90) can be assigned to female rats, mice, and hamsters...
  5. ncbi Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate
    A Elder
    Department of Environmental Medicine, University of Rochester, New York 14642, USA
    Exp Lung Res 31:527-46. 2005
    ..These results indicate that cells other than AMs can recruit inflammatory cells into the lungs during acute LPS-induced injury and that AMs play an important suppressive role in the innate pulmonary inflammatory response...
  6. ncbi On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats
    Alison Elder
    Department of Environmental Medicine, University of Rochester, New York 14642, USA
    Inhal Toxicol 16:41-53. 2004
    ..Furthermore, they demonstrate that on-road exposures are feasible and could be performed in future studies with more continuous particle exposures...
  7. ncbi Systemic effects of inhaled ultrafine particles in two compromised, aged rat strains
    Alison C P Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Inhal Toxicol 16:461-71. 2004
    ....
  8. ncbi Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate
    A C P Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Exp Lung Res 30:105-20. 2004
    ..We conclude that ITIH of clodronate liposomes in rats is both efficient and useful for examining the role of AMs in pulmonary toxicology...
  9. ncbi Pulmonary inflammatory response to inhaled ultrafine particles is modified by age, ozone exposure, and bacterial toxin
    A C Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York, USA
    Inhal Toxicol 12:227-46. 2000
    ....
  10. ncbi Induction of adaptation to inhaled lipopolysaccharide in young and old rats and mice
    A C Elder
    Department of Environmental Medicine, University of Rochester, 575 Elmwood Ave, Box EHSC, Rochester, NY 14642, USA
    Inhal Toxicol 12:225-43. 2000
    ..Therefore, we have demonstrated that inhaled low-dose LPS can induce adaptation to subsequent higher doses, much as has been shown for other toxicants that induce oxidative lung injury...
  11. ncbi Translocation of inhaled ultrafine particles to the brain
    G Oberdorster
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Inhal Toxicol 16:437-45. 2004
    ..It could provide a portal of entry into the CNS for solid UFP, circumventing the tight blood-brain barrier. Whether this translocation of inhaled UFP can cause CNS effects needs to be determined in future studies...