A C Elder

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint Translocation and effects of ultrafine particles outside of the lung
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, NY 14642, USA
    Clin Occup Environ Med 5:785-96. 2006
  2. doi request reprint Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation
    Brittany L Baisch
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Box 850, Rochester, NY 14642, USA
    Part Fibre Toxicol 11:5. 2014
  3. doi request reprint Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, NY, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:434-50. 2009
  4. pmc Translocation of inhaled ultrafine manganese oxide particles to the central nervous system
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Environ Health Perspect 114:1172-8. 2006
  5. ncbi request reprint Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology
    Alison Elder
    Department of Environmental Medicine, University of Rochester, NY 14642, USA
    Toxicol Sci 88:614-29. 2005
  6. ncbi request reprint Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate
    A Elder
    Department of Environmental Medicine, University of Rochester, New York 14642, USA
    Exp Lung Res 31:527-46. 2005
  7. ncbi request reprint On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats
    Alison Elder
    Department of Environmental Medicine, University of Rochester, New York 14642, USA
    Inhal Toxicol 16:41-53. 2004
  8. ncbi request reprint Systemic effects of inhaled ultrafine particles in two compromised, aged rat strains
    Alison C P Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Inhal Toxicol 16:461-71. 2004
  9. ncbi request reprint Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate
    A C P Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Exp Lung Res 30:105-20. 2004
  10. ncbi request reprint Pulmonary inflammatory response to inhaled ultrafine particles is modified by age, ozone exposure, and bacterial toxin
    A C Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York, USA
    Inhal Toxicol 12:227-46. 2000

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Translocation and effects of ultrafine particles outside of the lung
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, NY 14642, USA
    Clin Occup Environ Med 5:785-96. 2006
    ..These translocation processes are explored here as well potential consequences that result from exposure of extrapulmonary organs to inhaled ultrafine particles...
  2. doi request reprint Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation
    Brittany L Baisch
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Box 850, Rochester, NY 14642, USA
    Part Fibre Toxicol 11:5. 2014
    ..We hypothesize that the delivered dose rate is a key determinant of the inflammatory response in the RT when the deposited dose is constant...
  3. doi request reprint Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, NY, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:434-50. 2009
    ....
  4. pmc Translocation of inhaled ultrafine manganese oxide particles to the central nervous system
    Alison Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Environ Health Perspect 114:1172-8. 2006
    ..Studies in monkeys with intranasally instilled gold ultrafine particles (UFPs; <100 nm) and in rats with inhaled carbon UFPs suggested that solid UFPs deposited in the nose travel along the olfactory nerve to the olfactory bulb...
  5. ncbi request reprint Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology
    Alison Elder
    Department of Environmental Medicine, University of Rochester, NY 14642, USA
    Toxicol Sci 88:614-29. 2005
    ..From these results, a subchronic NOAEL of 1 mg/m(3) respirable HSCb (Printex 90) can be assigned to female rats, mice, and hamsters...
  6. ncbi request reprint Lung inflammation induced by endotoxin is enhanced in rats depleted of alveolar macrophages with aerosolized clodronate
    A Elder
    Department of Environmental Medicine, University of Rochester, New York 14642, USA
    Exp Lung Res 31:527-46. 2005
    ..These results indicate that cells other than AMs can recruit inflammatory cells into the lungs during acute LPS-induced injury and that AMs play an important suppressive role in the innate pulmonary inflammatory response...
  7. ncbi request reprint On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats
    Alison Elder
    Department of Environmental Medicine, University of Rochester, New York 14642, USA
    Inhal Toxicol 16:41-53. 2004
    ..Furthermore, they demonstrate that on-road exposures are feasible and could be performed in future studies with more continuous particle exposures...
  8. ncbi request reprint Systemic effects of inhaled ultrafine particles in two compromised, aged rat strains
    Alison C P Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Inhal Toxicol 16:461-71. 2004
    ....
  9. ncbi request reprint Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate
    A C P Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Exp Lung Res 30:105-20. 2004
    ..We conclude that ITIH of clodronate liposomes in rats is both efficient and useful for examining the role of AMs in pulmonary toxicology...
  10. ncbi request reprint Pulmonary inflammatory response to inhaled ultrafine particles is modified by age, ozone exposure, and bacterial toxin
    A C Elder
    Department of Environmental Medicine, University of Rochester, Rochester, New York, USA
    Inhal Toxicol 12:227-46. 2000
    ....
  11. ncbi request reprint Induction of adaptation to inhaled lipopolysaccharide in young and old rats and mice
    A C Elder
    Department of Environmental Medicine, University of Rochester, 575 Elmwood Ave, Box EHSC, Rochester, NY 14642, USA
    Inhal Toxicol 12:225-43. 2000
    ..Therefore, we have demonstrated that inhaled low-dose LPS can induce adaptation to subsequent higher doses, much as has been shown for other toxicants that induce oxidative lung injury...
  12. ncbi request reprint Translocation of inhaled ultrafine particles to the brain
    G Oberdorster
    Department of Environmental Medicine, University of Rochester, Rochester, New York 14642, USA
    Inhal Toxicol 16:437-45. 2004
    ..It could provide a portal of entry into the CNS for solid UFP, circumventing the tight blood-brain barrier. Whether this translocation of inhaled UFP can cause CNS effects needs to be determined in future studies...