Research Topics
Species | Ali El SolhSummaryAffiliation: University at Buffalo Country: USA Publications
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Publications
Adhesion molecules in patients with coronary artery disease and moderate-to-severe obstructive sleep apneaAli A El-Solh
Department of Medicine, James P Nolan Clinical Research Center, University at Buffalo School of Medicine and Biomedical Sciences, Veterans Affairs Western New York Health Care System, Buffalo, NY, USA
Chest 121:1541-7. 2002..We hypothesized that soluble intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, L-selectin, and E-selectin levels are correlated with OSA independent of coexisting coronary artery disease (CAD)...
Noninvasive ventilation for prevention of post-extubation respiratory failure in obese patientsA A El-Solh
Western New York Respiratory Research Center, Dept of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, Erie County Medical Center, Buffalo, NY 14215, USA
Eur Respir J 28:588-95. 2006..In selected patients with chronic hypercarbia, early application of noninvasive ventilation may confer a survival benefit...
Clinical outcomes of type III Pseudomonas aeruginosa bacteremiaAli A El-Solh
Veterans Affairs Western New York Healthcare System, Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Buffalo, NY, USA
Crit Care Med 40:1157-63. 2012..However, the relationship between the type 3 secretion system and clinical outcomes in P. aeruginosa bacteremia has not been investigated...
Effect of oral decontamination with chlorhexidine on the incidence of nosocomial pneumonia: a meta-analysisLilibeth A Pineda
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
Crit Care 10:R35. 2006..The lack of benefit may reflect the few studies conducted in this area. Future trials should focus on a combination strategy of mechanical and pharmacological interventions...
Bicarbonate therapy in the treatment of septic shock: a second lookAli A El-Solh
The Veterans Affairs Western New York Healthcare System, Medical Research Blg 20 151 VISN02, 3495 Bailey Avenue, Buffalo, NY 14215 1199, USA
Intern Emerg Med 5:341-7. 2010..33%; 95% CI 19-51%, respectively; p = 0.79). Infusion of sodium bicarbonate in septic patients with arterial hyperlactatemia may facilitate weaning from mechanical ventilation and reduce length of ICU stay...
Ceftobiprole: a new broad spectrum cephalosporinAli El Solh
State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY 14215 1199, USA
Expert Opin Pharmacother 10:1675-86. 2009..The most frequent drug-related adverse event was dysgeusia. Ceftobiprole is intended for use in the hospital for the treatment of infections that frequently involve beta-lactam-resistant Gram-negative and Gram-positive organisms...
Update on the treatment of Pseudomonas aeruginosa pneumoniaAli A El Solh
Veterans Affairs Western New York Healthcare System, Buffalo, NY, USA
J Antimicrob Chemother 64:229-38. 2009..Among these, the anti-PcrV immunoglobulin G antibody that blocks the type III secretion system-mediated virulence of P. aeruginosa has recently entered Phase I/II clinical trials...
Effect of antibiotic guidelines on outcomes of hospitalized patients with nursing home-acquired pneumoniaAli A El Solh
Veterans Affairs Western New York Healthcare System, Medical Research, Bldg 20 151 VISN02, 3495 Bailey Avenue, Buffalo, NY 14215, USA
J Am Geriatr Soc 57:1030-5. 2009....
Predicting optimal CPAP by neural network reduces titration failure: a randomized studyAli El Solh
Department of Medicine, Western New York Respiratory Research Center, Buffalo, USA
Sleep Breath 13:325-30. 2009....
Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumoniaAli A El Solh
Western New York Respiratory Research Center, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
Am J Respir Crit Care Med 178:513-9. 2008..aeruginosa in patients with VAP may persist in the alveolar space despite adequate antimicrobial therapy. We hypothesized that failure to eradicate P. aeruginosa from the lung is linked to type III secretory system (TTSS) isolates...
Hemostatic implications of endothelial cell apoptosis in obstructive sleep apneaAli A El Solh
Western New York Respiratory Research Center, Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
Sleep Breath 12:331-7. 2008..In patients with OSA, increased prothrombotic factors are strongly determined by apoptotic CECs. Treatment with nCPAP may alleviate the coagulation propensity...
Triggering receptors expressed on myeloid cells in pulmonary aspiration syndromesAli A El Solh
Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
Intensive Care Med 34:1012-9. 2008..To investigate the potential role of serum and alveolar soluble triggering receptor expressed on myeloid cells (sTREM-1) as a biological marker of pulmonary aspiration syndromes...
Pharmacologic prevention of aspiration pneumonia: a systematic reviewAli A El Solh
Westem New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, Buffalo, New York 14215, USA
Am J Geriatr Pharmacother 5:352-62. 2007....
Outcome of septic shock in older adults after implementation of the sepsis "bundle"Ali A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Western New York Respiratory Research Center, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 14215, USA
J Am Geriatr Soc 56:272-8. 2008..To evaluate the effect on 28-day mortality of implementation of a sepsis "bundle" protocol for the treatment of older adults with septic shock...
Nursing home-acquired pneumoniaAli A El Solh
Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215 1199, USA
Semin Respir Crit Care Med 30:16-25. 2009..Prevention remains the cornerstone of reducing the incidence of disease. Despite the advance in medical services, mortality from NHAP remains high...
A comparative study of community- and nursing home-acquired empyema thoracisAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Western New York Respiratory Research Center, Buffalo, New York, USA
J Am Geriatr Soc 55:1847-52. 2007..To compare the clinical presentation, microbiological features, and outcomes of patients with community-acquired empyema (CAE) with those of patients with nursing home-acquired empyema (NHAE)...
Matrix metalloproteases in bronchoalveolar lavage fluid of patients with type III Pseudomonas aeruginosa pneumoniaAli A El-Solh
The Veterans Affairs Western New York Healthcare System, Medical Research Building 20, 3495 Bailey Avenue, Buffalo, NY 14215 1199, USA
J Infect 59:49-55. 2009..Differential expression of matrix metalloproteinases (MMPs) induced by type III effector proteins may herald an irreversible lung injury...
Airway management in the obese patientAli A El Solh
Veterans Affairs Western New York Healthcare System, Medical Research Building 20, Buffalo, NY 14215 1199, USA
Clin Chest Med 30:555-68, ix. 2009....
Lectin-like oxidized low-density lipoprotein receptor-1 modulates endothelial apoptosis in obstructive sleep apneaMorohunfolu E Akinnusi
Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
Chest 140:1503-10. 2011..The objective of this study was to investigate the association between LOX-1 in freshly harvested human venous endothelial cells and apoptotic circulating endothelial cells in patients with obstructive sleep apnea (OSA)...
Association between pneumonia and oral care in nursing home residentsAli A El-Solh
Medical Research, Bldg 20 151 VISN02, VA Western New York Healthcare System, Buffalo, NY 14215 1199, USA
Lung 189:173-80. 2011..While resources may be limited in long-term-care facilities, incorporating oral care in daily routine practice helps to reduce systemic diseases and to promote overall quality of life in nursing home residents...
Physicians' attitudes toward guidelines for the treatment of hospitalized nursing home-acquired pneumoniaAli A El-Solh
The Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
J Am Med Dir Assoc 12:270-6. 2011..To assess physician awareness, attitudes, and barriers toward the 2005 American Thoracic Society (ATS)/Infectious Diseases Society of America (IDSA) guidelines for the treatment of hospitalized nursing home-acquired pneumonia (NHAP)...
Diagnostic use of serum procalcitonin levels in pulmonary aspiration syndromesAli A El-Solh
Veterans Affairs Western New York Healthcare System, Buffalo, NY, USA
Crit Care Med 39:1251-6. 2011..To assess the predictive accuracy of serum procalcitonin in distinguishing bacterial aspiration pneumonia from aspiration pneumonitis...
Nursing home acquired pneumonia: approach to managementAli A El-Solh
The Veterans Affairs Western New York Healthcare System, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine and Social and Preventive Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York, USA
Curr Opin Infect Dis 24:148-51. 2011..This review focuses on recent recommendations for diagnostic work up, validity of prognostic models, and current approach to treatment of nursing home acquired pneumonia (NHAP)...
Management of pneumonia in the nursing homeAli A El-Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
Chest 138:1480-5. 2010..As of January 2010, Medicare no longer pays for consultation codes; thus, practitioners must instead use existing evaluation and management service codes when providing these services...
Positive airway pressure adherence in veterans with posttraumatic stress disorderAli A El-Solh
The Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215, USA
Sleep 33:1495-500. 2010....
Combined oral appliance and positive airway pressure therapy for obstructive sleep apnea: a pilot studyAli A El-Solh
The Veterans Affairs Western New York Healthcare System, Medical Research, Bldg 20 151 VISN02, 3495 Bailey Avenue, Buffalo, NY 14215 1199, USA
Sleep Breath 15:203-8. 2011..Mandibular advancement devices (MADs) are proven alternative therapy although not universally effective. A combination of nasal CPAP and MAD may provide another option for CPAP-intolerant patients with incomplete response to MAD...
Nursing home-acquired pneumonia: a review of risk factors and therapeutic approachesAli A El-Solh
Division of Pulmonary, Critical Care and Sleep Medicine, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
Curr Med Res Opin 26:2707-14. 2010..To review the risk factors, etiologic profile, treatment approaches, and guidelines for the management of nursing home-acquired pneumonia (NHAP)...
Endothelial function in patients with post-CPAP residual sleepinessAli A El-Solh
The Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
J Clin Sleep Med 6:251-5. 2010....
Validity of severity scores in hospitalized patients with nursing home-acquired pneumoniaAli A El-Solh
VA Western New York Healthcare System, Buffalo, NY 14215 1199, USA
Chest 138:1371-6. 2010....
Antibiotic prescription patterns in hospitalized patients with nursing home-acquired pneumoniaAli A El-Solh
The Veterans Affairs Western New York Healthcare System, Buffalo, New York 14215 1199, USA
J Hosp Med 5:E5-10. 2010..Much less is known about the antibiotic prescribing patterns for hospitalized non-critically ill patients with nursing home-acquired pneumonia (NHAP)...
Predicting effective continuous positive airway pressure in sleep apnea using an artificial neural networkAli A El Solh
Western New York Respiratory Research Center, Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, School of Medicine and Biomedical Sciences, 462 Grider Street, Buffalo, NY, USA
Sleep Med 8:471-7. 2007....
Diagnostic yield of quantitative endotracheal aspirates in patients with severe nursing home-acquired pneumoniaAli A El Solh
Western New York Respiratory Research Center, Department of Medicine, State University of New York, Buffalo School of Medicine and Biomedical Sciences, Grider Street Buffalo, New York 14215, USA
Crit Care 11:R57. 2007....
Predicting active pulmonary tuberculosis using an artificial neural networkA A El-Solh
Department of Medicine, Erie County Medical Center, Buffalo, NY 14215, USA
Chest 116:968-73. 1999..Nosocomial outbreaks of tuberculosis (TB) have been attributed to unrecognized pulmonary TB. Accurate assessment in identifying index cases of active TB is essential in preventing transmission of the disease...
A longitudinal study of idiopathic exudative lymphocytic pleural effusion in older peopleAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York 14215, USA
J Am Geriatr Soc 53:1957-60. 2005..To assess the long-term prognosis of older patients with idiopathic exudative lymphocytic pleural effusion...
Indicators of recurrent hospitalization for pneumonia in the elderlyAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York 14215, USA
J Am Geriatr Soc 52:2010-5. 2004..To identify modifiable risk factors of late unplanned readmissions for elderly with community-acquired pneumonia...
Colonization of dental plaques: a reservoir of respiratory pathogens for hospital-acquired pneumonia in institutionalized eldersAli A El-Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, 462 Grider St, Buffalo, NY 14215, USA
Chest 126:1575-82. 2004..We sought to investigate the association between dental plaque (DP) colonization and lower respiratory tract infection in hospitalized institutionalized elders using molecular genotyping...
Impact of invasive strategy on management of antimicrobial treatment failure in institutionalized older people with severe pneumoniaAli A El-Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, James P Nolan Clinical Research Center, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
Am J Respir Crit Care Med 166:1038-43. 2002..When combined with microbial investigation, direct visualization of the tracheobronchial tree might be useful in determining the presence of bacterial pneumonia...
Indicators of potentially drug-resistant bacteria in severe nursing home-acquired pneumoniaAli A El Solh
Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
Clin Infect Dis 39:474-80. 2004..Knowledge of the determinant factors responsible for the presence of antimicrobial-resistant pathogens in severe nursing home-acquired pneumonia (NHAP) is deemed essential for antibiotic selection...
Procoagulant and fibrinolytic activity in ventilator-associated pneumonia: impact of inadequate antimicrobial therapyAli A El-Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, School of Medicine and Biomedical Sciences, Erie County Medical Center, University at Buffalo, Buffalo, NY 14215, USA
Intensive Care Med 30:1914-20. 2004..To determine the homeostatic balance of patients with ventilator-associated pneumonia (VAP) with respect to the adequacy of antimicrobial therapy...
Extubation failure in the elderlyAli A El Solh
Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14215, USA
Respir Med 98:661-8. 2004..7; 95% CI 1.2-6.7) were independently associated with extubation failure in the old. Objective measurements of cough strength and secretion volume are needed to reduce the morbidity of elderly patients at risk for extubation failure...
Clinical approach to the critically ill, morbidly obese patientAli A El-Solh
Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, New York, USA
Am J Respir Crit Care Med 169:557-61. 2004
Radiographic resolution of community-acquired bacterial pneumonia in the elderlyAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York, USA
J Am Geriatr Soc 52:224-9. 2004....
Nosocomial pneumonia in elderly patients following cardiac surgeryAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, USA
Respir Med 100:729-36. 2006..To identify modifiable risk factors of nosocomial pneumonia (NP) in elderly patients post-cardiac surgery...
Alveolar plasminogen activator inhibitor-1 predicts ARDS in aspiration pneumonitisAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, USA
Intensive Care Med 32:110-5. 2006..To test the hypothesis that alveolar plasminogen activator inhibitor-1 (PAI-1) can identify patients with witnessed aspiration at risk for progression to acute respiratory distress syndrome (ARDS)...
Allopurinol improves endothelial function in sleep apnoea: a randomised controlled studyA A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Dept of Medicine, School of Medicine and Biomedical Sciences and Veterans Affairs Medical Center, University at Buffalo, Buffalo, NY, USA
Eur Respir J 27:997-1002. 2006..Allopurinol improves endothelial dysfunction in patients with moderate-to-severe obstructive sleep apnoea. These observations suggest that xanthine oxidase contributes significantly to vasodilatory impairment...
Endothelial cell apoptosis in obstructive sleep apnea: a link to endothelial dysfunctionAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, USA
Am J Respir Crit Care Med 175:1186-91. 2007..Patients with obstructive sleep apnea (OSA) are at increased risk for cardiovascular diseases. Injury of endothelial cells has been advanced as an initial trigger to atherosclerosis...
A comparative study of the complications of surgical tracheostomy in morbidly obese critically ill patientsAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, State University of New York, Buffalo, NY 14215, USA
Crit Care 11:R3. 2007..The aim of this study was to determine the incidence and severity of complications associated with open tracheostomy in critically ill morbidly obese patients during hospitalization...
Clinical and hemostatic responses to treatment in ventilator-associated pneumonia: role of bacterial pathogensAli A El Solh
Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14215, USA
Crit Care Med 35:490-6. 2007....
Overview of respiratory failure in older adultsAli A El Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14215, USA
J Intensive Care Med 21:345-51. 2006..Finally, allocation of potentially limited health care resources necessitates knowing about the risk-benefit of mechanical ventilation and other treatment for respiratory failure in this population...
Validity of an artificial neural network in predicting discharge destination from a postacute geriatric rehabilitation unitA A El-Solh
Department of Medicine, Erie County Medical Center, Buffalo, NY 14215, USA
Arch Phys Med Rehabil 81:1388-93. 2000..To develop an artificial neural network (ANN) designed to predict discharge destination from postacute geriatric rehabilitation units...
Etiology of severe pneumonia in the very elderlyA A El-Solh
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Erie County Medical Center and Kaleida Health Care System, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
Am J Respir Crit Care Med 163:645-51. 2001..7; 95% CI, 1.8 to 15.6; p = 0.02), and inadequate antimicrobial therapy (OR, 2.6; 95% CI, 1.4 to 23.9; p = 0.034). Further studies should focus on identifying effective antimicrobial regimens in randomized trials...
Determinants of short and long term functional recovery after hospitalization for community-acquired pneumonia in the elderly: role of inflammatory markersAli El Solh
Western New York Respiratory Research Center, 462 Grider Street, Buffalo, NY 14215, USA
BMC Geriatr 6:12. 2006....
Morbid obesity in the medical ICUA El-Solh
Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, James P Nolan Clinical Research Center, University at Buffalo School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA
Chest 120:1989-97. 2001..Study objective: To describe the clinical course, complications, and prognostic factors of morbidly obese patients admitted to the ICU compared to a control group of nonobese patients...
Microbiology of severe aspiration pneumonia in institutionalized elderlyAli A El-Solh
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine, NY, USA
Am J Respir Crit Care Med 167:1650-4. 2003..001) as independent risk factors of poor outcome. In view of the rising resistance to antimicrobial agents, the importance of adding anaerobic coverage for aspiration pneumonia in institutionalized elders needs to be reexamined...
Biomarkers in the diagnosis of aspiration syndromesPhilippe Abou Jaoude
The Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
Expert Rev Mol Diagn 10:309-19. 2010..The present review summarizes the different biomarkers that have been studied in aspiration and those who might have a potential clinical use in the future...
Swallowing disorders post orotracheal intubation in the elderlyAli El Solh
Division of Pulmonary, Critical Care and Sleep Medicine, University of Buffalo School of Medicine and Biomedical Sciences, Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, USA
Intensive Care Med 29:1451-5. 2003..CONCLUSIONS: Critically ill elderly patients exhibit delayed resolution of swallowing impairment post extubation. FEES should be considered for those with impaired preadmission functional status...
Does linezolid modulate lung innate immunity in a murine model of methicillin-resistant Staphylococcus aureus pneumonia?Morohunfolu E Akinnusi
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences and School of Public Health and Health Professions, Buffalo, NY, USA
Crit Care Med 39:1944-52. 2011..Recent investigations suggest that linezolid is superior to vancomycin in achieving clinical cure in patients with nosocomial pneumonia. We hypothesized that linezolid may exhibit anti-inflammatory properties in vivo model of pneumonia...
National survey to assess the content and availability of difficult-airway carts in critical-care units in the United StatesJahan Porhomayon
VA Western New York Healthcare System, Division of Critical Care and Pain Medicine, Department of Anesthesiology, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Rm 203C, 3495 Bailey Ave, Buffalo, NY 14215, USA
J Anesth 24:811-4. 2010..It is strongly recommended that a DAC be present. What constitutes the ideal contents of a DAC is open to questions. We hope discussion will lead to consensus of what should or should not be included on the cart...
Severe community-acquired pneumonia: approach to therapyLilibeth Pineda
Western New York Respiratory Research Center, Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
Expert Opin Pharmacother 8:593-606. 2007..Non-antimicrobial adjuvant therapies including non-invasive ventilation and immunomodulatory agents are emerging as promising area for future development...
Effect of obesity on intensive care morbidity and mortality: a meta-analysisMorohunfolu E Akinnusi
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Western New York Respiratory Research Center, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
Crit Care Med 36:151-8. 2008..To evaluate the effect of obesity on intensive care unit mortality, duration of mechanical ventilation, and intensive care unit length of stay among critically ill medical and surgical patients...
Association between plasma endothelin-1 levels and Cheyne-Stokes respiration in patients with congestive heart failureAli A El-Solh
Department of Medicine, James P Nolan Clinical Research Center, Erie County Medical Center 124215, USA
Chest 121:1928-34. 2002....
Tigecycline attenuates staphylococcal superantigen-induced T-cell proliferation and production of cytokines and chemokinesRanime Saliba
The Veterans Affairs Western New York Healthcare System, Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, New York 14215 1199, USA
Immunopharmacol Immunotoxicol 31:583-8. 2009..Results demonstrated that tigecycline alters cytokine production and reduces T-cell proliferation in vitro suggesting an immunomodulatory activity independent of its antimicrobial effect...
Impact of nasal continuous positive airway pressure therapy on markers of platelet activation in patients with obstructive sleep apneaMorohunfolu E Akinnusi
Division of Pulmonary, Critical Care, and Sleep Medicine, Western New York Respiratory Research Center, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, N Y, USA
Respiration 77:25-31. 2009..Exposure to CD40 ligand induces platelet-leukocyte conjugation, a heightened expression of inflammatory cytokines, matrix-degrading enzymes, and procoagulant factors...
The role of coagulation in pulmonary pathologyMorohunfolu E Akinnusi
Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, Buffalo, NY 14215, USA
Inflamm Allergy Drug Targets 6:201-9. 2007..Current efforts are directed at depicting multifaceted molecules capable of selective but simultaneous interference with relevant aspects of the dual coagulation-fibrinolytic pathway...
An official ATS statement: grading the quality of evidence and strength of recommendations in ATS guidelines and recommendationsHolger J Schunemann
Am J Respir Crit Care Med 174:605-14. 2006
