Ali El Solh

Summary

Affiliation: University at Buffalo
Country: USA

Publications

  1. ncbi request reprint Adhesion molecules in patients with coronary artery disease and moderate-to-severe obstructive sleep apnea
    Ali A El-Solh
    Department of Medicine, James P Nolan Clinical Research Center, University at Buffalo School of Medicine and Biomedical Sciences, Veterans Affairs Western New York Health Care System, Buffalo, NY, USA
    Chest 121:1541-7. 2002
  2. ncbi request reprint Noninvasive ventilation for prevention of post-extubation respiratory failure in obese patients
    A A El-Solh
    Western New York Respiratory Research Center, Dept of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, Erie County Medical Center, Buffalo, NY 14215, USA
    Eur Respir J 28:588-95. 2006
  3. pmc Clinical outcomes of type III Pseudomonas aeruginosa bacteremia
    Ali A El-Solh
    Veterans Affairs Western New York Healthcare System, Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Buffalo, NY, USA
    Crit Care Med 40:1157-63. 2012
  4. pmc Effect of oral decontamination with chlorhexidine on the incidence of nosocomial pneumonia: a meta-analysis
    Lilibeth A Pineda
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
    Crit Care 10:R35. 2006
  5. doi request reprint Bicarbonate therapy in the treatment of septic shock: a second look
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Medical Research Blg 20 151 VISN02, 3495 Bailey Avenue, Buffalo, NY 14215 1199, USA
    Intern Emerg Med 5:341-7. 2010
  6. doi request reprint Ceftobiprole: a new broad spectrum cephalosporin
    Ali El Solh
    State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY 14215 1199, USA
    Expert Opin Pharmacother 10:1675-86. 2009
  7. doi request reprint Update on the treatment of Pseudomonas aeruginosa pneumonia
    Ali A El Solh
    Veterans Affairs Western New York Healthcare System, Buffalo, NY, USA
    J Antimicrob Chemother 64:229-38. 2009
  8. doi request reprint Effect of antibiotic guidelines on outcomes of hospitalized patients with nursing home-acquired pneumonia
    Ali A El Solh
    Veterans Affairs Western New York Healthcare System, Medical Research, Bldg 20 151 VISN02, 3495 Bailey Avenue, Buffalo, NY 14215, USA
    J Am Geriatr Soc 57:1030-5. 2009
  9. doi request reprint Predicting optimal CPAP by neural network reduces titration failure: a randomized study
    Ali El Solh
    Department of Medicine, Western New York Respiratory Research Center, Buffalo, USA
    Sleep Breath 13:325-30. 2009
  10. pmc Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia
    Ali A El Solh
    Western New York Respiratory Research Center, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
    Am J Respir Crit Care Med 178:513-9. 2008

Collaborators

Detail Information

Publications65

  1. ncbi request reprint Adhesion molecules in patients with coronary artery disease and moderate-to-severe obstructive sleep apnea
    Ali A El-Solh
    Department of Medicine, James P Nolan Clinical Research Center, University at Buffalo School of Medicine and Biomedical Sciences, Veterans Affairs Western New York Health Care System, Buffalo, NY, USA
    Chest 121:1541-7. 2002
    ..We hypothesized that soluble intercellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, L-selectin, and E-selectin levels are correlated with OSA independent of coexisting coronary artery disease (CAD)...
  2. ncbi request reprint Noninvasive ventilation for prevention of post-extubation respiratory failure in obese patients
    A A El-Solh
    Western New York Respiratory Research Center, Dept of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, Erie County Medical Center, Buffalo, NY 14215, USA
    Eur Respir J 28:588-95. 2006
    ..In selected patients with chronic hypercarbia, early application of noninvasive ventilation may confer a survival benefit...
  3. pmc Clinical outcomes of type III Pseudomonas aeruginosa bacteremia
    Ali A El-Solh
    Veterans Affairs Western New York Healthcare System, Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Buffalo, NY, USA
    Crit Care Med 40:1157-63. 2012
    ..However, the relationship between the type 3 secretion system and clinical outcomes in P. aeruginosa bacteremia has not been investigated...
  4. pmc Effect of oral decontamination with chlorhexidine on the incidence of nosocomial pneumonia: a meta-analysis
    Lilibeth A Pineda
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
    Crit Care 10:R35. 2006
    ..Studies using topical antiseptic agents yielded mixed results. We hypothesized that the use of chlorhexidine for oral decontamination would reduce the incidence of nosocomial pneumonia in patients requiring mechanical ventilation...
  5. doi request reprint Bicarbonate therapy in the treatment of septic shock: a second look
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Medical Research Blg 20 151 VISN02, 3495 Bailey Avenue, Buffalo, NY 14215 1199, USA
    Intern Emerg Med 5:341-7. 2010
    ..33%; 95% CI 19-51%, respectively; p = 0.79). Infusion of sodium bicarbonate in septic patients with arterial hyperlactatemia may facilitate weaning from mechanical ventilation and reduce length of ICU stay...
  6. doi request reprint Ceftobiprole: a new broad spectrum cephalosporin
    Ali El Solh
    State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY 14215 1199, USA
    Expert Opin Pharmacother 10:1675-86. 2009
    ..The most frequent drug-related adverse event was dysgeusia. Ceftobiprole is intended for use in the hospital for the treatment of infections that frequently involve beta-lactam-resistant Gram-negative and Gram-positive organisms...
  7. doi request reprint Update on the treatment of Pseudomonas aeruginosa pneumonia
    Ali A El Solh
    Veterans Affairs Western New York Healthcare System, Buffalo, NY, USA
    J Antimicrob Chemother 64:229-38. 2009
    ..Among these, the anti-PcrV immunoglobulin G antibody that blocks the type III secretion system-mediated virulence of P. aeruginosa has recently entered Phase I/II clinical trials...
  8. doi request reprint Effect of antibiotic guidelines on outcomes of hospitalized patients with nursing home-acquired pneumonia
    Ali A El Solh
    Veterans Affairs Western New York Healthcare System, Medical Research, Bldg 20 151 VISN02, 3495 Bailey Avenue, Buffalo, NY 14215, USA
    J Am Geriatr Soc 57:1030-5. 2009
    ....
  9. doi request reprint Predicting optimal CPAP by neural network reduces titration failure: a randomized study
    Ali El Solh
    Department of Medicine, Western New York Respiratory Research Center, Buffalo, USA
    Sleep Breath 13:325-30. 2009
    ....
  10. pmc Persistent infection with Pseudomonas aeruginosa in ventilator-associated pneumonia
    Ali A El Solh
    Western New York Respiratory Research Center, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
    Am J Respir Crit Care Med 178:513-9. 2008
    ..aeruginosa in patients with VAP may persist in the alveolar space despite adequate antimicrobial therapy. We hypothesized that failure to eradicate P. aeruginosa from the lung is linked to type III secretory system (TTSS) isolates...
  11. doi request reprint Hemostatic implications of endothelial cell apoptosis in obstructive sleep apnea
    Ali A El Solh
    Western New York Respiratory Research Center, Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
    Sleep Breath 12:331-7. 2008
    ..In patients with OSA, increased prothrombotic factors are strongly determined by apoptotic CECs. Treatment with nCPAP may alleviate the coagulation propensity...
  12. doi request reprint Triggering receptors expressed on myeloid cells in pulmonary aspiration syndromes
    Ali A El Solh
    Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
    Intensive Care Med 34:1012-9. 2008
    ..To investigate the potential role of serum and alveolar soluble triggering receptor expressed on myeloid cells (sTREM-1) as a biological marker of pulmonary aspiration syndromes...
  13. doi request reprint Pharmacologic prevention of aspiration pneumonia: a systematic review
    Ali A El Solh
    Westem New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, Buffalo, New York 14215, USA
    Am J Geriatr Pharmacother 5:352-62. 2007
    ....
  14. ncbi request reprint Outcome of septic shock in older adults after implementation of the sepsis "bundle"
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Western New York Respiratory Research Center, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, 14215, USA
    J Am Geriatr Soc 56:272-8. 2008
    ..To evaluate the effect on 28-day mortality of implementation of a sepsis "bundle" protocol for the treatment of older adults with septic shock...
  15. doi request reprint Nursing home-acquired pneumonia
    Ali A El Solh
    Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215 1199, USA
    Semin Respir Crit Care Med 30:16-25. 2009
    ..Prevention remains the cornerstone of reducing the incidence of disease. Despite the advance in medical services, mortality from NHAP remains high...
  16. ncbi request reprint A comparative study of community- and nursing home-acquired empyema thoracis
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Western New York Respiratory Research Center, Buffalo, New York, USA
    J Am Geriatr Soc 55:1847-52. 2007
    ..To compare the clinical presentation, microbiological features, and outcomes of patients with community-acquired empyema (CAE) with those of patients with nursing home-acquired empyema (NHAE)...
  17. pmc Matrix metalloproteases in bronchoalveolar lavage fluid of patients with type III Pseudomonas aeruginosa pneumonia
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Medical Research Building 20, 3495 Bailey Avenue, Buffalo, NY 14215 1199, USA
    J Infect 59:49-55. 2009
    ..Differential expression of matrix metalloproteinases (MMPs) induced by type III effector proteins may herald an irreversible lung injury...
  18. doi request reprint Airway management in the obese patient
    Ali A El Solh
    Veterans Affairs Western New York Healthcare System, Medical Research Building 20, Buffalo, NY 14215 1199, USA
    Clin Chest Med 30:555-68, ix. 2009
    ....
  19. doi request reprint Lectin-like oxidized low-density lipoprotein receptor-1 modulates endothelial apoptosis in obstructive sleep apnea
    Morohunfolu E Akinnusi
    Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
    Chest 140:1503-10. 2011
    ..The objective of this study was to investigate the association between LOX-1 in freshly harvested human venous endothelial cells and apoptotic circulating endothelial cells in patients with obstructive sleep apnea (OSA)...
  20. doi request reprint Association between pneumonia and oral care in nursing home residents
    Ali A El-Solh
    Medical Research, Bldg 20 151 VISN02, VA Western New York Healthcare System, Buffalo, NY 14215 1199, USA
    Lung 189:173-80. 2011
    ..While resources may be limited in long-term-care facilities, incorporating oral care in daily routine practice helps to reduce systemic diseases and to promote overall quality of life in nursing home residents...
  21. doi request reprint Physicians' attitudes toward guidelines for the treatment of hospitalized nursing home-acquired pneumonia
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
    J Am Med Dir Assoc 12:270-6. 2011
    ..To assess physician awareness, attitudes, and barriers toward the 2005 American Thoracic Society (ATS)/Infectious Diseases Society of America (IDSA) guidelines for the treatment of hospitalized nursing home-acquired pneumonia (NHAP)...
  22. pmc Diagnostic use of serum procalcitonin levels in pulmonary aspiration syndromes
    Ali A El-Solh
    Veterans Affairs Western New York Healthcare System, Buffalo, NY, USA
    Crit Care Med 39:1251-6. 2011
    ..To assess the predictive accuracy of serum procalcitonin in distinguishing bacterial aspiration pneumonia from aspiration pneumonitis...
  23. doi request reprint Nursing home acquired pneumonia: approach to management
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine and Social and Preventive Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York, USA
    Curr Opin Infect Dis 24:148-51. 2011
    ..This review focuses on recent recommendations for diagnostic work up, validity of prognostic models, and current approach to treatment of nursing home acquired pneumonia (NHAP)...
  24. doi request reprint Management of pneumonia in the nursing home
    Ali A El-Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
    Chest 138:1480-5. 2010
    ..As of January 2010, Medicare no longer pays for consultation codes; thus, practitioners must instead use existing evaluation and management service codes when providing these services...
  25. pmc Positive airway pressure adherence in veterans with posttraumatic stress disorder
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215, USA
    Sleep 33:1495-500. 2010
    ....
  26. doi request reprint Combined oral appliance and positive airway pressure therapy for obstructive sleep apnea: a pilot study
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Medical Research, Bldg 20 151 VISN02, 3495 Bailey Avenue, Buffalo, NY 14215 1199, USA
    Sleep Breath 15:203-8. 2011
    ..Mandibular advancement devices (MADs) are proven alternative therapy although not universally effective. A combination of nasal CPAP and MAD may provide another option for CPAP-intolerant patients with incomplete response to MAD...
  27. doi request reprint Nursing home-acquired pneumonia: a review of risk factors and therapeutic approaches
    Ali A El-Solh
    Division of Pulmonary, Critical Care and Sleep Medicine, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
    Curr Med Res Opin 26:2707-14. 2010
    ..To review the risk factors, etiologic profile, treatment approaches, and guidelines for the management of nursing home-acquired pneumonia (NHAP)...
  28. pmc Endothelial function in patients with post-CPAP residual sleepiness
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
    J Clin Sleep Med 6:251-5. 2010
    ....
  29. doi request reprint Validity of severity scores in hospitalized patients with nursing home-acquired pneumonia
    Ali A El-Solh
    VA Western New York Healthcare System, Buffalo, NY 14215 1199, USA
    Chest 138:1371-6. 2010
    ....
  30. doi request reprint Antibiotic prescription patterns in hospitalized patients with nursing home-acquired pneumonia
    Ali A El-Solh
    The Veterans Affairs Western New York Healthcare System, Buffalo, New York 14215 1199, USA
    J Hosp Med 5:E5-10. 2010
    ..Much less is known about the antibiotic prescribing patterns for hospitalized non-critically ill patients with nursing home-acquired pneumonia (NHAP)...
  31. ncbi request reprint Predicting effective continuous positive airway pressure in sleep apnea using an artificial neural network
    Ali A El Solh
    Western New York Respiratory Research Center, Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, School of Medicine and Biomedical Sciences, 462 Grider Street, Buffalo, NY, USA
    Sleep Med 8:471-7. 2007
    ....
  32. pmc Diagnostic yield of quantitative endotracheal aspirates in patients with severe nursing home-acquired pneumonia
    Ali A El Solh
    Western New York Respiratory Research Center, Department of Medicine, State University of New York, Buffalo School of Medicine and Biomedical Sciences, Grider Street Buffalo, New York 14215, USA
    Crit Care 11:R57. 2007
    ....
  33. ncbi request reprint Predicting active pulmonary tuberculosis using an artificial neural network
    A A El-Solh
    Department of Medicine, Erie County Medical Center, Buffalo, NY 14215, USA
    Chest 116:968-73. 1999
    ..Nosocomial outbreaks of tuberculosis (TB) have been attributed to unrecognized pulmonary TB. Accurate assessment in identifying index cases of active TB is essential in preventing transmission of the disease...
  34. ncbi request reprint A longitudinal study of idiopathic exudative lymphocytic pleural effusion in older people
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York 14215, USA
    J Am Geriatr Soc 53:1957-60. 2005
    ..To assess the long-term prognosis of older patients with idiopathic exudative lymphocytic pleural effusion...
  35. ncbi request reprint Indicators of recurrent hospitalization for pneumonia in the elderly
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York 14215, USA
    J Am Geriatr Soc 52:2010-5. 2004
    ..To identify modifiable risk factors of late unplanned readmissions for elderly with community-acquired pneumonia...
  36. ncbi request reprint Colonization of dental plaques: a reservoir of respiratory pathogens for hospital-acquired pneumonia in institutionalized elders
    Ali A El-Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, 462 Grider St, Buffalo, NY 14215, USA
    Chest 126:1575-82. 2004
    ..We sought to investigate the association between dental plaque (DP) colonization and lower respiratory tract infection in hospitalized institutionalized elders using molecular genotyping...
  37. ncbi request reprint Impact of invasive strategy on management of antimicrobial treatment failure in institutionalized older people with severe pneumonia
    Ali A El-Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, James P Nolan Clinical Research Center, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
    Am J Respir Crit Care Med 166:1038-43. 2002
    ..When combined with microbial investigation, direct visualization of the tracheobronchial tree might be useful in determining the presence of bacterial pneumonia...
  38. ncbi request reprint Indicators of potentially drug-resistant bacteria in severe nursing home-acquired pneumonia
    Ali A El Solh
    Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
    Clin Infect Dis 39:474-80. 2004
    ..Knowledge of the determinant factors responsible for the presence of antimicrobial-resistant pathogens in severe nursing home-acquired pneumonia (NHAP) is deemed essential for antibiotic selection...
  39. ncbi request reprint Procoagulant and fibrinolytic activity in ventilator-associated pneumonia: impact of inadequate antimicrobial therapy
    Ali A El-Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, School of Medicine and Biomedical Sciences, Erie County Medical Center, University at Buffalo, Buffalo, NY 14215, USA
    Intensive Care Med 30:1914-20. 2004
    ..To determine the homeostatic balance of patients with ventilator-associated pneumonia (VAP) with respect to the adequacy of antimicrobial therapy...
  40. ncbi request reprint Extubation failure in the elderly
    Ali A El Solh
    Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14215, USA
    Respir Med 98:661-8. 2004
    ..7; 95% CI 1.2-6.7) were independently associated with extubation failure in the old. Objective measurements of cough strength and secretion volume are needed to reduce the morbidity of elderly patients at risk for extubation failure...
  41. ncbi request reprint Clinical approach to the critically ill, morbidly obese patient
    Ali A El-Solh
    Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, New York, USA
    Am J Respir Crit Care Med 169:557-61. 2004
  42. ncbi request reprint Radiographic resolution of community-acquired bacterial pneumonia in the elderly
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, New York, USA
    J Am Geriatr Soc 52:224-9. 2004
    ....
  43. ncbi request reprint Nosocomial pneumonia in elderly patients following cardiac surgery
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, USA
    Respir Med 100:729-36. 2006
    ..To identify modifiable risk factors of nosocomial pneumonia (NP) in elderly patients post-cardiac surgery...
  44. ncbi request reprint Alveolar plasminogen activator inhibitor-1 predicts ARDS in aspiration pneumonitis
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, USA
    Intensive Care Med 32:110-5. 2006
    ..To test the hypothesis that alveolar plasminogen activator inhibitor-1 (PAI-1) can identify patients with witnessed aspiration at risk for progression to acute respiratory distress syndrome (ARDS)...
  45. ncbi request reprint Allopurinol improves endothelial function in sleep apnoea: a randomised controlled study
    A A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Dept of Medicine, School of Medicine and Biomedical Sciences and Veterans Affairs Medical Center, University at Buffalo, Buffalo, NY, USA
    Eur Respir J 27:997-1002. 2006
    ..Allopurinol improves endothelial dysfunction in patients with moderate-to-severe obstructive sleep apnoea. These observations suggest that xanthine oxidase contributes significantly to vasodilatory impairment...
  46. ncbi request reprint Endothelial cell apoptosis in obstructive sleep apnea: a link to endothelial dysfunction
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, USA
    Am J Respir Crit Care Med 175:1186-91. 2007
    ..Patients with obstructive sleep apnea (OSA) are at increased risk for cardiovascular diseases. Injury of endothelial cells has been advanced as an initial trigger to atherosclerosis...
  47. pmc A comparative study of the complications of surgical tracheostomy in morbidly obese critically ill patients
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, State University of New York, Buffalo, NY 14215, USA
    Crit Care 11:R3. 2007
    ..The aim of this study was to determine the incidence and severity of complications associated with open tracheostomy in critically ill morbidly obese patients during hospitalization...
  48. ncbi request reprint Clinical and hemostatic responses to treatment in ventilator-associated pneumonia: role of bacterial pathogens
    Ali A El Solh
    Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14215, USA
    Crit Care Med 35:490-6. 2007
    ....
  49. ncbi request reprint Overview of respiratory failure in older adults
    Ali A El Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY 14215, USA
    J Intensive Care Med 21:345-51. 2006
    ..Finally, allocation of potentially limited health care resources necessitates knowing about the risk-benefit of mechanical ventilation and other treatment for respiratory failure in this population...
  50. ncbi request reprint Validity of an artificial neural network in predicting discharge destination from a postacute geriatric rehabilitation unit
    A A El-Solh
    Department of Medicine, Erie County Medical Center, Buffalo, NY 14215, USA
    Arch Phys Med Rehabil 81:1388-93. 2000
    ..To develop an artificial neural network (ANN) designed to predict discharge destination from postacute geriatric rehabilitation units...
  51. ncbi request reprint Etiology of severe pneumonia in the very elderly
    A A El-Solh
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Erie County Medical Center and Kaleida Health Care System, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York 14215, USA
    Am J Respir Crit Care Med 163:645-51. 2001
    ..7; 95% CI, 1.8 to 15.6; p = 0.02), and inadequate antimicrobial therapy (OR, 2.6; 95% CI, 1.4 to 23.9; p = 0.034). Further studies should focus on identifying effective antimicrobial regimens in randomized trials...
  52. pmc Determinants of short and long term functional recovery after hospitalization for community-acquired pneumonia in the elderly: role of inflammatory markers
    Ali El Solh
    Western New York Respiratory Research Center, 462 Grider Street, Buffalo, NY 14215, USA
    BMC Geriatr 6:12. 2006
    ....
  53. ncbi request reprint Morbid obesity in the medical ICU
    A El-Solh
    Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, James P Nolan Clinical Research Center, University at Buffalo School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA
    Chest 120:1989-97. 2001
    ..Study objective: To describe the clinical course, complications, and prognostic factors of morbidly obese patients admitted to the ICU compared to a control group of nonobese patients...
  54. ncbi request reprint Microbiology of severe aspiration pneumonia in institutionalized elderly
    Ali A El-Solh
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine, NY, USA
    Am J Respir Crit Care Med 167:1650-4. 2003
    ..001) as independent risk factors of poor outcome. In view of the rising resistance to antimicrobial agents, the importance of adding anaerobic coverage for aspiration pneumonia in institutionalized elders needs to be reexamined...
  55. pmc Biomarkers in the diagnosis of aspiration syndromes
    Philippe Abou Jaoude
    The Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215 1199, USA
    Expert Rev Mol Diagn 10:309-19. 2010
    ..The present review summarizes the different biomarkers that have been studied in aspiration and those who might have a potential clinical use in the future...
  56. ncbi request reprint Swallowing disorders post orotracheal intubation in the elderly
    Ali El Solh
    Division of Pulmonary, Critical Care and Sleep Medicine, University of Buffalo School of Medicine and Biomedical Sciences, Erie County Medical Center, 462 Grider Street, Buffalo, NY 14215, USA
    Intensive Care Med 29:1451-5. 2003
    ..The purpose of this study was to assess the prevalence and recovery time of swallowing dysfunction after prolonged endotracheal intubation in critically ill elderly patients compared to a younger cohort...
  57. doi request reprint Does linezolid modulate lung innate immunity in a murine model of methicillin-resistant Staphylococcus aureus pneumonia?
    Morohunfolu E Akinnusi
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences and School of Public Health and Health Professions, Buffalo, NY, USA
    Crit Care Med 39:1944-52. 2011
    ..Recent investigations suggest that linezolid is superior to vancomycin in achieving clinical cure in patients with nosocomial pneumonia. We hypothesized that linezolid may exhibit anti-inflammatory properties in vivo model of pneumonia...
  58. doi request reprint National survey to assess the content and availability of difficult-airway carts in critical-care units in the United States
    Jahan Porhomayon
    VA Western New York Healthcare System, Division of Critical Care and Pain Medicine, Department of Anesthesiology, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Rm 203C, 3495 Bailey Ave, Buffalo, NY 14215, USA
    J Anesth 24:811-4. 2010
    ..It is strongly recommended that a DAC be present. What constitutes the ideal contents of a DAC is open to questions. We hope discussion will lead to consensus of what should or should not be included on the cart...
  59. ncbi request reprint Severe community-acquired pneumonia: approach to therapy
    Lilibeth Pineda
    Western New York Respiratory Research Center, Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
    Expert Opin Pharmacother 8:593-606. 2007
    ..Non-antimicrobial adjuvant therapies including non-invasive ventilation and immunomodulatory agents are emerging as promising area for future development...
  60. ncbi request reprint Effect of obesity on intensive care morbidity and mortality: a meta-analysis
    Morohunfolu E Akinnusi
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Western New York Respiratory Research Center, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, NY, USA
    Crit Care Med 36:151-8. 2008
    ..To evaluate the effect of obesity on intensive care unit mortality, duration of mechanical ventilation, and intensive care unit length of stay among critically ill medical and surgical patients...
  61. ncbi request reprint Association between plasma endothelin-1 levels and Cheyne-Stokes respiration in patients with congestive heart failure
    Ali A El-Solh
    Department of Medicine, James P Nolan Clinical Research Center, Erie County Medical Center 124215, USA
    Chest 121:1928-34. 2002
    ....
  62. doi request reprint Tigecycline attenuates staphylococcal superantigen-induced T-cell proliferation and production of cytokines and chemokines
    Ranime Saliba
    The Veterans Affairs Western New York Healthcare System, Department of Medicine, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, New York 14215 1199, USA
    Immunopharmacol Immunotoxicol 31:583-8. 2009
    ..Results demonstrated that tigecycline alters cytokine production and reduces T-cell proliferation in vitro suggesting an immunomodulatory activity independent of its antimicrobial effect...
  63. doi request reprint Impact of nasal continuous positive airway pressure therapy on markers of platelet activation in patients with obstructive sleep apnea
    Morohunfolu E Akinnusi
    Division of Pulmonary, Critical Care, and Sleep Medicine, Western New York Respiratory Research Center, Department of Medicine, State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, N Y, USA
    Respiration 77:25-31. 2009
    ..Exposure to CD40 ligand induces platelet-leukocyte conjugation, a heightened expression of inflammatory cytokines, matrix-degrading enzymes, and procoagulant factors...
  64. ncbi request reprint The role of coagulation in pulmonary pathology
    Morohunfolu E Akinnusi
    Western New York Respiratory Research Center, Division of Pulmonary, Critical Care, and Sleep Medicine, Erie County Medical Center, Buffalo, NY 14215, USA
    Inflamm Allergy Drug Targets 6:201-9. 2007
    ..Current efforts are directed at depicting multifaceted molecules capable of selective but simultaneous interference with relevant aspects of the dual coagulation-fibrinolytic pathway...
  65. ncbi request reprint An official ATS statement: grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations
    Holger J Schunemann
    Am J Respir Crit Care Med 174:605-14. 2006