Rif S El-Mallakh

Summary

Affiliation: University of Louisville
Country: USA

Publications

  1. ncbi request reprint Evaluation of consequences of implementation of police crisis intervention team in Louisville
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    J Ky Med Assoc 106:435-7. 2008
  2. ncbi request reprint Waiting room crowding and agitation in a dedicated psychiatric emergency service
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Ann Clin Psychiatry 24:140-2. 2012
  3. pmc Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures
    Martin E Brown
    Department of Neurology
    Ther Clin Risk Manag 6:103-9. 2010
  4. ncbi request reprint Adherence and assured administration of medications in bipolar patients
    Peggy L El-Mallakh
    Medcenter One, 501 East Broadway, Suite 340, Louisville, KY 40202, USA
    Curr Drug Deliv 10:706-12. 2013
  5. doi request reprint The dopamine D4/D2 receptor antagonist affinity ratio as a predictor of anti-aggression medication efficacy
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Med Hypotheses 80:530-3. 2013
  6. doi request reprint A 40-week double-blind aripiprazole versus lithium follow-up of a 12-week acute phase study (total 52 weeks) in bipolar I disorder
    Rif S El-Mallakh
    University of Louisville, Louisville, KY 40202, USA
    J Affect Disord 136:258-66. 2012
  7. doi request reprint Studies of long-term use of antidepressants: how should the data from them be interpreted?
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY, USA
    CNS Drugs 26:97-109. 2012
  8. ncbi request reprint Switching from other agents to extended-release carbamazepine in acute mania
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisvilile School of Medicine, Louisville, KY, USA
    Psychopharmacol Bull 41:52-8. 2008
  9. ncbi request reprint Medication adherence and the use of long-acting antipsychotics in bipolar disorder
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    J Psychiatr Pract 13:79-85. 2007
  10. ncbi request reprint Aberrant regulation of endogenous ouabain-like factor in bipolar subjects
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Psychiatry Res 178:116-20. 2010

Detail Information

Publications73

  1. ncbi request reprint Evaluation of consequences of implementation of police crisis intervention team in Louisville
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    J Ky Med Assoc 106:435-7. 2008
    ..8% in 2004, P < 0.01). The data suggests that the introduction of CIT has had an overall positive effect on outcomes of situations in which mentally ill subjects are confronted by police officers...
  2. ncbi request reprint Waiting room crowding and agitation in a dedicated psychiatric emergency service
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Ann Clin Psychiatry 24:140-2. 2012
    ..Emergency department crowding is a growing problem that impacts patient care and safety. The effect of crowding has not been examined in emergency psychiatric services...
  3. pmc Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures
    Martin E Brown
    Department of Neurology
    Ther Clin Risk Manag 6:103-9. 2010
    ..Eslicarbazepine is an effective and reasonably well-tolerated adjunct in patients with suboptimal control of their partial seizures...
  4. ncbi request reprint Adherence and assured administration of medications in bipolar patients
    Peggy L El-Mallakh
    Medcenter One, 501 East Broadway, Suite 340, Louisville, KY 40202, USA
    Curr Drug Deliv 10:706-12. 2013
    ..Controlled studies with second generation agents confirm this impression. Depot antipsychotics, including long-acting first- and second-generation agents, can be important adjuncts in the long-term management of bipolar illness. ..
  5. doi request reprint The dopamine D4/D2 receptor antagonist affinity ratio as a predictor of anti-aggression medication efficacy
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Med Hypotheses 80:530-3. 2013
    ..This hypothesis can be tested using a new antipsychotic, asenapine, which is the only other antipsychotic with antagonistic affinity ratio of D4/D2>1...
  6. doi request reprint A 40-week double-blind aripiprazole versus lithium follow-up of a 12-week acute phase study (total 52 weeks) in bipolar I disorder
    Rif S El-Mallakh
    University of Louisville, Louisville, KY 40202, USA
    J Affect Disord 136:258-66. 2012
    ..This is the only long-term, double-blind study comparing lithium and aripiprazole...
  7. doi request reprint Studies of long-term use of antidepressants: how should the data from them be interpreted?
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY, USA
    CNS Drugs 26:97-109. 2012
    ....
  8. ncbi request reprint Switching from other agents to extended-release carbamazepine in acute mania
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisvilile School of Medicine, Louisville, KY, USA
    Psychopharmacol Bull 41:52-8. 2008
    ..There is a dearth of available knowledge relating to the efficacy of switching from one psychotropic agent to another in treating patients with acute mania...
  9. ncbi request reprint Medication adherence and the use of long-acting antipsychotics in bipolar disorder
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    J Psychiatr Pract 13:79-85. 2007
    ..The availability of a long-acting atypical antipsychotic raises the possibility of using this agent to prevent bipolar relapse...
  10. ncbi request reprint Aberrant regulation of endogenous ouabain-like factor in bipolar subjects
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Psychiatry Res 178:116-20. 2010
    ..15) in bipolar subjects compared to non-psychiatric controls. Other endogenous cardenolides did not vary significantly. The endogenous cardenolide, OLF, may be aberrantly controlled in bipolar illness...
  11. ncbi request reprint MDMA (Ecstasy)
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Ann Clin Psychiatry 19:45-52. 2007
    ..Its use in Western countries appears to be increasing, particularly among young individuals...
  12. ncbi request reprint Medical decision-making by psychiatry residents
    Rif El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Acad Psychiatry 31:326-8. 2007
    ....
  13. doi request reprint Long-term use of pramipexole in bipolar depression: a naturalistic retrospective chart review
    Rif S El-Mallakh
    School of Medicine, University of Louisville, Louisville, KY, USA
    Psychiatr Q 81:207-13. 2010
    ..There were no changes in mania ratings for up to 36 months. Long-term outcome of adjunctive pramipexole appears to be adequate, with apparent maintenance of effect for over 9 months...
  14. ncbi request reprint Lithiated lemon-lime sodas
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Medcenter One, 501 E Broadway, Louisville, KY 40202, USA
    Am J Psychiatry 164:1662. 2007
  15. doi request reprint Adverse event load in bipolar participants receiving either carbamazepine immediate-release or extended-release capsules: a blinded, randomized study
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Int Clin Psychopharmacol 24:145-9. 2009
    ..2+/-1.7 vs. IR 7.2+/-1.3 microg/ml, P = 0.005). Total AE load was directly related to CBZ level only in participants receiving the IR formulation. In conclusion, ERCC is better tolerated than IR CBZ in bipolar patients...
  16. doi request reprint Comorbid anxiety in bipolar disorder alters treatment and prognosis
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Medcenter One, 501 E Broadway, Louisville, KY 40202, USA
    Psychiatr Q 79:139-50. 2008
    ..Identification of anxiety disorders in bipolar patients is important. The treatment plan needs to balance the potential benefit and harm of antidepressant administration...
  17. ncbi request reprint A blinded, randomized comparison of immediate-release and extended-release carbamazepine capsules in manic and depressed bipolar subjects
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Ann Clin Psychiatry 22:3-8. 2010
    ..It is available in 2 formulations: immediate-release (IR) and extended-release carbamazepine capsules (ERCC). The relative efficacy of these formulations in acutely ill bipolar patients has not been previously investigated...
  18. doi request reprint Bipolar disorder: an update
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Postgrad Med 122:24-31. 2010
    ..The use of multiple agents appears to be superior to monotherapy in relapse prevention. Despite the many advances in the pharmacotherapy of bipolar disorder, the overall prognosis of this severe illness does not appear to have changed...
  19. ncbi request reprint Bipolar II disorder: current and future treatment options
    Rif El-Mallakh
    Dept of Psychiatry, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Ann Clin Psychiatry 18:259-66. 2006
    ..This review attempts to summarize available data on agents useful in treating patients with the disease...
  20. doi request reprint A comparison of two fixed doses of aripiprazole with placebo in acutely relapsed, hospitalized patients with bipolar disorder I (manic or mixed) in subpopulations (CN138-007)
    Rif S El Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville, KY 40292, USA
    Eur Neuropsychopharmacol 20:776-83. 2010
    ..A high placebo response rate may have accounted for the lack of separation between treatment groups...
  21. ncbi request reprint Use of antidepressants to treat depression in bipolar disorder
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Kentucky 40292, USA
    Psychiatr Serv 53:580-4. 2002
    ..Antidepressants should be used with caution in the treatment of bipolar depression...
  22. ncbi request reprint Chronic depression in bipolar disorder
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40292, USA
    Am J Psychiatry 163:1337-41; quiz 1478. 2006
  23. doi request reprint Hallucinations, psuedohallucinations, and parahallucinations
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine in Louisville, Kentucky 40202, USA
    Psychiatry 73:34-42. 2010
    ..There are several clinical phenomena that resemble hallucinations which are inadequately studied because the terminology defining them is inadequate...
  24. ncbi request reprint Follow-up after inpatient psychiatric hospitalization with partial control of the system responsiveness variable
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40291, USA
    Psychiatry 67:294-8. 2004
    ..35, p = .067). Despite partial control of the system responsiveness variable, compliance with aftercare was suboptimal. This was due to a combination of client vulnerability variables and uncontrollable system responsiveness factors...
  25. doi request reprint Tardive dysphoria: the role of long term antidepressant use in-inducing chronic depression
    Rif S El-Mallakh
    Mood Disorders Research Program, The University of Louisville Depression Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Med Hypotheses 76:769-73. 2011
    ..This is an emerging evidence that, in some individuals, persistent use of antidepressants may be prodepressant...
  26. doi request reprint Response of sodium pump to ouabain challenge in human glioblastoma cells in culture
    Xian Huang
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, KY, USA
    World J Biol Psychiatry 10:884-92. 2009
    ..These results suggest that disturbance of ion regulation induces changes in glial cell sodium regulatory systems which are normalized by lithium treatment...
  27. ncbi request reprint Intracerebroventricular administration of ouabain as a model of mania in rats
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40292, USA
    Bipolar Disord 5:362-5. 2003
    ....
  28. doi request reprint Effect of ethacrynic acid on the sodium- and potassium-activated adenosine triphosphatase activity and expression in Old Order Amish bipolar individuals
    Mary O Huff
    Department of Biology, Bellarmine University, Louisville, Kentucky, USA
    J Affect Disord 123:303-7. 2010
    ..However, all of these studies have been in out-bred populations. In an attempt to reduce the genetic variability associated with this observation, we examined this phenomenon within an isolated breeding population...
  29. doi request reprint Memantine reduces mania-like symptoms in animal models
    Yonglin Gao
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, United States
    Psychiatry Res 188:366-71. 2011
    ..0 μM). Ouabain-induced hyperlocomotion was normalized with acute and chronic lithium and chronic use of memantine. Memantine delayed the onset of ouabain-induced-cycling in hippocampal slices. Memantine may have antimanic properties...
  30. doi request reprint Hallucinations, pseudohallucinations, and severity of suicidal ideation among emergency psychiatry patients
    Praveen Penagaluri
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY, USA
    Crisis 31:53-6. 2010
    ..This study investigated relative relationships between auditory hallucinations and nonpsychotic hallucinations (pseudohallucinations), and suicidal risk...
  31. doi request reprint Antidepressant discontinuation in bipolar depression: a Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) randomized clinical trial of long-term effectiveness and safety
    S Nassir Ghaemi
    Mood Disorders Program, Department of Psychiatry, Tufts Medical Center, 800 Washington St, Box 1007, Boston, MA 02111, USA
    J Clin Psychiatry 71:372-80. 2010
    ..To assess long-term effectiveness and safety of randomized antidepressant discontinuation after acute recovery from bipolar depression...
  32. ncbi request reprint Efficacy of olanzapine and haloperidol in an animal model of mania
    Rif S El-Mallakh
    Mood Disorders Research Program, University of Louisville School of Medicine, Louisville, Kentucky 40292, United States
    Prog Neuropsychopharmacol Biol Psychiatry 30:1261-4. 2006
    ..Antipsychotic agents have demonstrated efficacy in the management of acute mania. This study was undertaken to determine the prophylactic efficacy of olanzapine and haloperidol in the ouabain mania model...
  33. ncbi request reprint Sleep disturbances in euthymic bipolar patients
    Sharon Brill
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, Louisville, KY, USA
    Ann Clin Psychiatry 23:113-6. 2011
    ..Sleep disturbance has been implicated in both prodromal and syndromal phases of bipolar illness...
  34. ncbi request reprint Mimicking human bipolar ion dysregulation models mania in rats
    Laura Herman
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Neurosci Biobehav Rev 31:874-81. 2007
    ..While additional characterization of the model is required, the ouabain model for bipolar illness is the only available animal model that fulfills the three criteria for an adequate animal model for bipolar illness...
  35. ncbi request reprint Psychiatric disposition of patients brought in by crisis intervention team police officers
    Gordon Strauss
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kenfucky, USA
    Community Ment Health J 41:223-8. 2005
    ..CIT is composed of uniformed officers who receive extensive training in crisis intervention and psychiatric issues and who are preferentially called to investigate police calls that may involve a mentally ill individual...
  36. ncbi request reprint Is bipolar disorder overdiagnosed among patients with substance abuse?
    Christopher Stewart
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Bipolar Disord 9:646-8. 2007
    ....
  37. ncbi request reprint Antipsychotic medications in the treatment of bipolar disorder
    Anton A Subuh Surja
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Curr Drug Targets 7:1217-24. 2006
    ..Finally, there are a small number of interesting studies suggesting utility in bipolar depression. This paper will critically review available randomized clinical trials utilizing antipsychotic agents in bipolar disorder...
  38. ncbi request reprint Antidepressant exposure in bipolar children
    David Cicero
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Psychiatry 66:317-22. 2003
    ..Although far from conclusive, these data are consistent with the hypothesis that antidepressant treatment is associated with a manic episode earlier than might occur spontaneously...
  39. ncbi request reprint Lithium normalizes elevated intracellular sodium
    Xian Huang
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Loiusville, KY 40292, USA
    Bipolar Disord 9:298-300. 2007
    ..Reduction of sodium influx is a proposed shared mechanism of action of effective mood stabilizers, but direct documentation of this effect for lithium has never been demonstrated...
  40. ncbi request reprint Naturalistic long-term use of methylphenidate in bipolar disorder
    Eric Lydon
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    J Clin Psychopharmacol 26:516-8. 2006
    ..3 +/- 9.9 to 69.3 +/- 10.6 (P = 0.006). Methylphenidate seems to be safe in the naturalistic setting. Controlled studies are needed to confirm its efficacy and safety in bipolar depression...
  41. ncbi request reprint Fertility and childhood bipolar disorder
    Anton Agus S Surja
    University of Louisville, Department of Psychiatry, 501 E Broadway, Suite 340, Louisville, KY 40202, United States
    Med Hypotheses 69:587-9. 2007
    ..These pharmacologic and social changes may have all conspired to increase reproductive success of bipolar subjects, giving rise to a new generation of bipolar patients with earlier onset and more severe manifestation of their disorder...
  42. doi request reprint Effect of dopamine on intracellular sodium: a common pathway for pharmacological mechanism of action in bipolar illness
    Rona J Roberts
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    World J Biol Psychiatry 11:181-7. 2010
    ..The recent increase of reports of documented efficacy of first- and second-generation antipsychotics in the control of mania offers a new opportunity to gain insight into the pathophysiological mechanism of bipolar disorder...
  43. doi request reprint Effect of ionic stress on apoptosis and the expression of TRPM2 in human olfactory neuroepithelial-derived progenitors
    Yonglin Gao
    Department of Psychiatry and Behavioral Sciences, University of Louisville, School of Medicine, Louisville, KY 40292, USA
    World J Biol Psychiatry 11:972-84. 2010
    ..TRPM2, a nonselective cation channel, is involved in apoptosis and is possibly linked with BD. In this study, monensin, a sodium ionophore, was used to model the increase [Na(+)](in) and [Ca(2+)](in) seen in BD patients...
  44. ncbi request reprint When to suspect bipolar disorder
    Muruga Loganathan
    Allegheny General Hospital, Pittsburgh, PA, USA
    J Fam Pract 59:682-8. 2010
    ..Bipolar disease is often misdiagnosed, sometimes repeatedly. The screening tool and tips you'll find here will help you identify patients without delay...
  45. ncbi request reprint BDNF expression in lymphoblastoid cell lines carrying BDNF SNPs associated with bipolar disorder
    Yonglin Gao
    Mood Disorder Research Program, Department of Psychiatry and Behavioral Science, School of Medicine, University of Louisville, Louisville, Kentucky 40292, USA
    Psychiatr Genet 22:253-5. 2012
    ..To determine whether single nucleotide polymorphisms (SNPs) of the brain-derived neurotrophic factor (BDNF) that have been associated with bipolar illness are associated with physiological dysfunction...
  46. doi request reprint Antidepressant-associated chronic irritable dysphoria (ACID) in STEP-BD patients
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, 501 East Broadway, Medcenter One, Suite 340, Louisville, Kentucky 40202, United States
    J Affect Disord 111:372-7. 2008
    ..This phenomenon has only been described in case series format, and has not been prospectively validated...
  47. ncbi request reprint Differential response of bipolar and normal control lymphoblastoid cell sodium pump to ethacrynic acid
    Rena Li
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, KY 40292, USA
    J Affect Disord 80:11-7. 2004
    ..Previous work has demonstrated a reduced adaptive response of the sodium pump to ethacrynic acid in lymphocytes obtained from bipolar subjects compared to psychiatrically normal controls...
  48. doi request reprint Patient outcome after treatment in a community-based crisis stabilization unit
    Charlotte L Adams
    University of Louisville School of Nursing, Louisville, KY, USA
    J Behav Health Serv Res 36:396-9. 2009
    ..Nonetheless, community-based crisis stabilization units appear to be cost-effective alternatives to inpatient hospitalization for selected patients...
  49. ncbi request reprint Implementation of a crisis intervention program for police response to mental health emergencies in Louisville
    Rif S El-Mallakh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky, USA
    J Ky Med Assoc 101:241-3. 2003
  50. doi request reprint The sensitivity and specificity of the mood disorders questionnaire varies with the intensity of mood illness
    Karthik S Suresh
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine in Louisville, Kentucky 40202, USA
    Psychiatr Q 84:337-41. 2013
    ..58, and specificity was 0.76 (P < 0.05). Positive predictive value was 0.50 and negative predictive value was 0.82. The specificity and sensitivity of the MDQ appears to vary with the illness severity of the patients screened...
  51. ncbi request reprint Dialysis of saliva improves accuracy of saliva lithium determinations
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry, School of Public Health and Information Sciences, University of Louisville, Louisville, KY 40292, USA
    Bipolar Disord 6:87-9. 2004
    ..Saliva lithium (Li) determinations have been explored as a potential alternative to plasma levels. Unfortunately, this method has been shown to be unreliable. Saliva has two major components: the aqueous and the mucopolysaccharide portions...
  52. doi request reprint Event-related potential study of the effects of emotional facial expressions on task performance in euthymic bipolar patients
    Estate M Sokhadze
    Cognitive Neuroscience Laboratory, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, 401 East Chestnut Street, Louisville, KY 40202, USA
    Appl Psychophysiol Biofeedback 36:1-13. 2011
    ..ERP responses to facial emotion in BD subjects varied significantly from normal controls. These variations are consistent with the common depressive symptomology seen in long term studies of bipolar subjects...
  53. ncbi request reprint Barometric pressure, emergency psychiatric visits, and violent acts
    Thomas J Schory
    Mood Disorders Research Program, Department of Psychiatry and Behavioural Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
    Can J Psychiatry 48:624-7. 2003
    ..Associations between human behaviour and psychiatric decompensation and weather variables have been inconsistent...
  54. ncbi request reprint Glial cell number and neuron/glial cell ratios in postmortem brains of bipolar individuals
    Rebecca A Brauch
    Mood Disorders Research Program, Department of Psychiatry, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    J Affect Disord 91:87-90. 2006
    ..There are several lines of evidence implicating a glial abnormality in the pathophysiology of bipolar disorder. Previous studies have reported a wide range of abnormalities but with little consistency between their findings...
  55. ncbi request reprint Positron emission tomography with fluorodeoxyglucose-F18 in an animal model of mania
    Matthew Tyler Hougland
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY, United States
    Psychiatry Res 164:166-71. 2008
    ..Pretreatment with lithium normalized (18)FDG uptake. These results mirror human studies...
  56. ncbi request reprint The effect of extreme marijuana use on the long-term course of bipolar I illness: a single case study
    Rif S El-Mallakh
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    J Psychoactive Drugs 39:201-2. 2007
    ..While not conclusive, the data suggest that marijuana may indeed have an effect on mood in bipolar patients that needs to be systematically examined...
  57. doi request reprint Cranial electrotherapy stimulation for the treatment of chronically symptomatic bipolar patients
    Mostafa Amr
    Department of Psychiatry, Mansoura Faculty of Medicine, Mansoura, Egypt
    J ECT 29:e31-2. 2013
    ..The aim of this study was to determine if cranial electrotherapy stimulation (CES) is beneficial in chronically symptomatic bipolar (CSBP) subjects...
  58. ncbi request reprint Smoking is associated with greater symptom load in bipolar disorder patients
    Mohamedlatif Saiyad
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Ann Clin Psychiatry 24:305-9. 2012
    ..Nicotine has several effects on mood and cognition. After many studies, the nature of the effect of smoking on mental illness is not clear...
  59. ncbi request reprint Validation of a diagnostic screening blood test for bipolar disorder
    Douglas B Woodruff
    Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Ann Clin Psychiatry 24:135-9. 2012
    ..78 and a specificity of .88. The current study was performed as a validation of the initial study...
  60. ncbi request reprint Weight gain occurs after onset of bipolar illness in overweight bipolar patients
    Amy Shah
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Ann Clin Psychiatry 18:239-41. 2006
    ..This has traditionally been attributed to medication and disease variables, but there have not been any studies that have investigated this directly...
  61. pmc Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia
    Hader A Mansour
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Bipolar Disord 11:701-10. 2009
    ..The results are plausible, based on prior studies of circadian abnormalities. As replications have not been attempted uniformly, we evaluated representative, common polymorphisms in all three disorders...
  62. ncbi request reprint Costs and savings associated with implementation of a police crisis intervention team
    Peggy L El-Mallakh
    From the College of Nursing, University of Kentucky, Lexington, and the Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky
    South Med J 107:391-5. 2014
    ..The objective of the study was to determine the total costs or total savings associated with implementing a CIT program in a medium-size city...
  63. doi request reprint Recurrent subcutaneous emphysema as a consequence of bulimia nervosa
    John M McCurdy
    Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Int J Eat Disord 46:92-4. 2013
    ..Pneumomediastinum is a rare complication of increased intrathoracic pressure. It is more likely to occur in individuals with nutritional deficiencies. Pneumomediastinum has been reported in some individuals with anorexia nervosa...
  64. ncbi request reprint Effect of ethacrynic acid on sodium pump alpha isoforms in SH-SY5Y cells
    Renee M Valdes
    Department of Psychiatry and Behavioral Science, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Bipolar Disord 5:123-8. 2003
    ..While this has been proposed to be important in the pathophysiology of bipolar illness, the response of neural tissues to ECA is unknown...
  65. ncbi request reprint Adjunctive antidepressant treatment for bipolar depression
    Rif S El-Mallakh
    N Engl J Med 357:615; author reply 615-6. 2007
  66. ncbi request reprint RE: Patient satisfaction in an inpatient dual psychiatric and substance dependence treatment program
    Rif S El-Mallakh
    J Ky Med Assoc 105:596-7. 2007
  67. ncbi request reprint Stimulating research: a prospective, randomized, double-blind, sham-controlled study of slow transcranial magnetic stimulation in depressed bipolar patients
    Rebecca L Tamas
    J Neuropsychiatry Clin Neurosci 19:198-9. 2007
  68. ncbi request reprint Serious rash with lamotrigine after carbamazepine discontinuation: a case report
    Anton A Subuh Surja
    J Clin Psychiatry 66:400-1. 2005
  69. ncbi request reprint Schizophrenia and the origins of shamanism among the Kwakiutl maritime cultures of Northwest North America: a hypothesis
    Rif S El-Mallakh
    Schizophr Res 86:329-30. 2006
  70. ncbi request reprint Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporter
    Hader A Mansour
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, U S A
    Ann Med 37:590-602. 2005
    ..Our analyses do not support association between SLC6A4 and BDI families. Further studies using sub-groups of BDI are worthwhile...
  71. ncbi request reprint Post lumbar-puncture headaches in schizophrenic and psychiatrically normal control subjects
    Rif S El-Mallakh
    Schizophr Res 77:111-2. 2005