Ahmed H K El-Hashash

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Children s Hospital Los Angeles, 4661 Sunset Boulevard, Los Angeles, CA 90027, USA
    J Cell Sci 125:4036-48. 2012
  2. pmc Numb expression and asymmetric versus symmetric cell division in distal embryonic lung epithelium
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Children s Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, CA 90027, USA
    J Histochem Cytochem 60:675-82. 2012
  3. pmc Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Children s Hospital Los Angeles, Keck School of Medicine of University of Southern California, 4650 Sunset Boulevard MS35, Los Angeles, CA 90027, USA
    Dev Biol 353:242-58. 2011
  4. pmc Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Childrens Hospital Los Angeles, Keck School of Medicine of University of Southern California, 4661 Sunset Boulevard, Los Angeles, CA 90027, USA
    Development 138:1395-407. 2011
  5. pmc Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Childrens Hospital Los Angeles, Keck School of Medicine of University of Southern California, 4650 Sunset Boulevard MS35, Los Angeles, CA 90027, USA
    Dev Biol 350:112-26. 2011
  6. doi request reprint Abrogation of Eya1/Six1 disrupts the saccular phase of lung morphogenesis and causes remodeling
    Karol Lu
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Children s Hospital Los Angeles, CA 90027, USA
    Dev Biol 382:110-23. 2013
  7. pmc Genes and signals regulating murine trophoblast cell development
    Ahmed H K El-Hashash
    Developmental Biology, Saban Research Institute, Children s Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, CA 90027, USA
    Mech Dev 127:1-20. 2010

Collaborators

Detail Information

Publications7

  1. pmc Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Children s Hospital Los Angeles, 4661 Sunset Boulevard, Los Angeles, CA 90027, USA
    J Cell Sci 125:4036-48. 2012
    ....
  2. pmc Numb expression and asymmetric versus symmetric cell division in distal embryonic lung epithelium
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Children s Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, CA 90027, USA
    J Histochem Cytochem 60:675-82. 2012
    ..These novel findings provide evidence for asymmetric cell division in distal epithelial stem/progenitor cells of embryonic lungs and a framework for future translationally oriented studies in this area...
  3. pmc Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Children s Hospital Los Angeles, Keck School of Medicine of University of Southern California, 4650 Sunset Boulevard MS35, Los Angeles, CA 90027, USA
    Dev Biol 353:242-58. 2011
    ..We propose that Six1 is hence critical for coordination of proper lung epithelial, mesenchymal and vascular development...
  4. pmc Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Childrens Hospital Los Angeles, Keck School of Medicine of University of Southern California, 4661 Sunset Boulevard, Los Angeles, CA 90027, USA
    Development 138:1395-407. 2011
    ..Indeed, genetic activation of Notch partially rescues Eya1(-/-) lung epithelial defects. These findings uncover novel functions for Eya1 as a crucial regulator of the complex behavior of distal embryonic lung epithelium...
  5. pmc Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung
    Ahmed H K El-Hashash
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Childrens Hospital Los Angeles, Keck School of Medicine of University of Southern California, 4650 Sunset Boulevard MS35, Los Angeles, CA 90027, USA
    Dev Biol 350:112-26. 2011
    ..We conclude, therefore, that Eya1 function is critical for proper coordination of lung epithelial, mesenchymal and vascular development...
  6. doi request reprint Abrogation of Eya1/Six1 disrupts the saccular phase of lung morphogenesis and causes remodeling
    Karol Lu
    Developmental Biology and Regenerative Medicine Program, Saban Research Institute, Children s Hospital Los Angeles, CA 90027, USA
    Dev Biol 382:110-23. 2013
    ..These findings uncover novel functions for Six1-Eya1-SHH pathway during the saccular phase of lung morphogenesis, providing a conceptual framework for future mechanistic and translational studies in this area...
  7. pmc Genes and signals regulating murine trophoblast cell development
    Ahmed H K El-Hashash
    Developmental Biology, Saban Research Institute, Children s Hospital Los Angeles, Keck School of Medicine of University of Southern California, Los Angeles, CA 90027, USA
    Mech Dev 127:1-20. 2010
    ..In particular, we discuss the molecular aspects of murine TGC differentiation. We also focus on the role of growth and transcription factors in TGC development...