Ahmed el-Ghannam

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi request reprint Model surfaces engineered with nanoscale roughness and RGD tripeptides promote osteoblast activity
    A R El-Ghannam
    Center for Bioactive Materials and Tissue Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biomed Mater Res A 68:615-27. 2004
  2. ncbi request reprint Bone reconstruction: from bioceramics to tissue engineering
    Ahmed el-Ghannam
    Center for Biomedical Engineering, Graduate School and Center for Oral Health Research, University of Kentucky Dental School, Lexington, KY 40506, USA
    Expert Rev Med Devices 2:87-101. 2005
  3. ncbi request reprint Effect of bioactive ceramic dissolution on the mechanism of bone mineralization and guided tissue growth in vitro
    A El-Ghannam
    Center for Biomedical Engineering, Wenner Gren Research Laboratory, Graduate School, University of Kentucky, Lexington, KY 40506, USA
    J Biomed Mater Res A 76:386-97. 2006
  4. ncbi request reprint Cyclosilicate nanocomposite: a novel resorbable bioactive tissue engineering scaffold for BMP and bone-marrow cell delivery
    A El-Ghannam
    Center for Biomedical Engineering, Graduate School, University of Kentucky, Lexington, Kentucky 40506, USA
    J Biomed Mater Res A 71:377-90. 2004
  5. ncbi request reprint Advanced bioceramic composite for bone tissue engineering: design principles and structure-bioactivity relationship
    Ahmed R El-Ghannam
    Tissue Engineering and Bioactive Materials Laboratory, Center for Biomedical Engineering, The Graduate School, Oral Health Science Center, School of Dentistry, University of Kentucky, Lexington, Kentucky 40506, USA
    J Biomed Mater Res A 69:490-501. 2004
  6. ncbi request reprint Enhancement of bone regeneration and graft material resorption using surface-modified bioactive glass in cortical and human maxillary cystic bone defects
    Ahmed el-Ghannam
    University of Kentucky, Center for Biomedical Engineering, Wenner Gren Research Laboratory, Graduate School, School of Dentistry, Lexington, Kentucky 40506 0070, USA
    Int J Oral Maxillofac Implants 19:184-91. 2004
  7. ncbi request reprint Bone engineering of the rabbit ulna
    Ahmed el-Ghannam
    Center for Biomedical Engineering and Center for Oral Health Research, College of Dentistry, University of Kentucky, Lexington, KY 40506, USA
    J Oral Maxillofac Surg 65:1495-502. 2007
  8. ncbi request reprint Enhancement of osteoblast gene expression by mechanically compatible porous Si-rich nanocomposite
    Gautam Gupta
    Center for Biomedical Engineering, Graduate School, University of Kentucky, Lexington, Kentucky 40506, USA
    J Biomed Mater Res B Appl Biomater 81:387-96. 2007
  9. ncbi request reprint Nanoporous delivery system to treat osteomyelitis and regenerate bone: gentamicin release kinetics and bactericidal effect
    Ahmed el-Ghannam
    Tissue Engineering and Bioactive Materials Laboratory, Center for Biomedical Engineering, The Graduate School, Wenner Gren Reserach Laboratory, University of Kentucky, Lexington, Kentucky 40506 0070, USA
    J Biomed Mater Res B Appl Biomater 73:277-84. 2005
  10. ncbi request reprint Dissolution kinetics of a Si-rich nanocomposite and its effect on osteoblast gene expression
    Gautam Gupta
    Center for Biomedical Engineering, Graduate School, University of Kentucky, Lexington, Kentucky 40506, USA
    J Biomed Mater Res A 80:486-96. 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Model surfaces engineered with nanoscale roughness and RGD tripeptides promote osteoblast activity
    A R El-Ghannam
    Center for Bioactive Materials and Tissue Engineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biomed Mater Res A 68:615-27. 2004
    ..Both sets of studies demonstrated that grafted molecules of RGD(S) enhance both osteoblast-like cell adhesion and function...
  2. ncbi request reprint Bone reconstruction: from bioceramics to tissue engineering
    Ahmed el-Ghannam
    Center for Biomedical Engineering, Graduate School and Center for Oral Health Research, University of Kentucky Dental School, Lexington, KY 40506, USA
    Expert Rev Med Devices 2:87-101. 2005
    ..Nanotechnology can provide an alternative way of processing porous bioceramics with high mechanical strength and enhanced bioactivity and resorbability...
  3. ncbi request reprint Effect of bioactive ceramic dissolution on the mechanism of bone mineralization and guided tissue growth in vitro
    A El-Ghannam
    Center for Biomedical Engineering, Wenner Gren Research Laboratory, Graduate School, University of Kentucky, Lexington, KY 40506, USA
    J Biomed Mater Res A 76:386-97. 2006
    ..The enhanced bioactivity reactions and strong stimulatory effect on bone cell function are attributed to the modified crystalline structure of the SCPC material...
  4. ncbi request reprint Cyclosilicate nanocomposite: a novel resorbable bioactive tissue engineering scaffold for BMP and bone-marrow cell delivery
    A El-Ghannam
    Center for Biomedical Engineering, Graduate School, University of Kentucky, Lexington, Kentucky 40506, USA
    J Biomed Mater Res A 71:377-90. 2004
    ..The SCPC-rhBMP-2-marrow cell hybrid may serve as an alternative to autologous bone grafting...
  5. ncbi request reprint Advanced bioceramic composite for bone tissue engineering: design principles and structure-bioactivity relationship
    Ahmed R El-Ghannam
    Tissue Engineering and Bioactive Materials Laboratory, Center for Biomedical Engineering, The Graduate School, Oral Health Science Center, School of Dentistry, University of Kentucky, Lexington, Kentucky 40506, USA
    J Biomed Mater Res A 69:490-501. 2004
    ..The new SCPC may be used for a wide variety of applications in the field of bone reconstruction including tissue-engineering scaffolds for cell and drug delivery...
  6. ncbi request reprint Enhancement of bone regeneration and graft material resorption using surface-modified bioactive glass in cortical and human maxillary cystic bone defects
    Ahmed el-Ghannam
    University of Kentucky, Center for Biomedical Engineering, Wenner Gren Research Laboratory, Graduate School, School of Dentistry, Lexington, Kentucky 40506 0070, USA
    Int J Oral Maxillofac Implants 19:184-91. 2004
    ..The authors hypothesize that creation of a calcium phosphate layer on the surface of bioactive glass before implantation will enhance bone regeneration and graft material resorption in bone defects...
  7. ncbi request reprint Bone engineering of the rabbit ulna
    Ahmed el-Ghannam
    Center for Biomedical Engineering and Center for Oral Health Research, College of Dentistry, University of Kentucky, Lexington, KY 40506, USA
    J Oral Maxillofac Surg 65:1495-502. 2007
    ..The purpose of the present preliminary study is to show that a novel 3-dimensional porous silica-calcium phosphate nanocomposite (SCPC) can provide a controlled release of rhBMP-2 and regenerate bone in a load-bearing segmental defect...
  8. ncbi request reprint Enhancement of osteoblast gene expression by mechanically compatible porous Si-rich nanocomposite
    Gautam Gupta
    Center for Biomedical Engineering, Graduate School, University of Kentucky, Lexington, Kentucky 40506, USA
    J Biomed Mater Res B Appl Biomater 81:387-96. 2007
    ..Results of the present study strongly suggest that porous, bioactive resorbable SCPCs can serve as tissue engineering scaffolds for cell delivery to treat load-bearing bone defects in orthopedic and maxillofacial surgeries...
  9. ncbi request reprint Nanoporous delivery system to treat osteomyelitis and regenerate bone: gentamicin release kinetics and bactericidal effect
    Ahmed el-Ghannam
    Tissue Engineering and Bioactive Materials Laboratory, Center for Biomedical Engineering, The Graduate School, Wenner Gren Reserach Laboratory, University of Kentucky, Lexington, Kentucky 40506 0070, USA
    J Biomed Mater Res B Appl Biomater 73:277-84. 2005
    ..Results of the study suggest that the silica-calcium phosphate nanocomposite can serve as a delivery vehicle for gentamicin to treat osteomyelitis and regenerate bone...
  10. ncbi request reprint Dissolution kinetics of a Si-rich nanocomposite and its effect on osteoblast gene expression
    Gautam Gupta
    Center for Biomedical Engineering, Graduate School, University of Kentucky, Lexington, Kentucky 40506, USA
    J Biomed Mater Res A 80:486-96. 2007
    ..The favorable physiochemical and bioactivity properties of Si-rich SCPC nanocomposite indicate that SCPC can have wide applications as a synthetic bone graft for cell delivery applications in tissue engineering...