MARK DOUGLAS EISNER

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc An integrated model of environmental factors in adult asthma lung function and disease severity: a cross-sectional study
    Laura Trupin
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Environ Health 9:24. 2010
  2. doi request reprint Passive smoking and adult asthma
    Mark D Eisner
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0111, USA
    Immunol Allergy Clin North Am 28:521-37, viii. 2008
  3. pmc Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol
    Mark D Eisner
    Department of Medicine, University of California, San Francisco, 350 Parnassus Avenue, Suite 609, San Francisco, CA 94117, USA
    Nicotine Tob Res 11:945-53. 2009
  4. doi request reprint Secondhand smoke at work
    Mark D Eisner
    University of California, San Francisco, San Francisco, California 94143 0111, USA
    Curr Opin Allergy Clin Immunol 10:121-6. 2010
  5. pmc Measurement of COPD severity using a survey-based score: validation in a clinically and physiologically characterized cohort
    Mark D Eisner
    University of California San Francisco, 505 Parnassus Ave, M 1097, San Francisco, CA 94143 0111, USA
    Chest 137:846-51. 2010
  6. pmc Directly measured secondhand smoke exposure and COPD health outcomes
    Mark D Eisner
    Department of Medicine, University of California, San Francisco, UCSF Box 0924, San Francisco, CA 94113 0924, USA
    BMC Pulm Med 6:12. 2006
  7. ncbi request reprint Risk factors for work disability in severe adult asthma
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94117, USA
    Am J Med 119:884-91. 2006
  8. pmc The impact of SHS exposure on health status and exacerbations among patients with COPD
    Mark D Eisner
    Division of Occupational and Environmental Medicine, University of California, San Francisco, CA 94143 0111, USA
    Int J Chron Obstruct Pulmon Dis 4:169-76. 2009
  9. pmc Influence of anxiety on health outcomes in COPD
    Mark D Eisner
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA 94143 0111, USA
    Thorax 65:229-34. 2010
  10. pmc Body composition and functional limitation in COPD
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, USA
    Respir Res 8:7. 2007

Research Grants

  1. ASTHMA HEALTH OUTCOMES FOLLOWING INTENSIVE CARE
    Mark Eisner; Fiscal Year: 2004
  2. Disability and Health Outcomes in COPD
    Mark Eisner; Fiscal Year: 2007

Detail Information

Publications65

  1. pmc An integrated model of environmental factors in adult asthma lung function and disease severity: a cross-sectional study
    Laura Trupin
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Environ Health 9:24. 2010
    ..We sought to evaluate the contribution of combined social and physical environmental exposures to adult asthma lung function and disease severity...
  2. doi request reprint Passive smoking and adult asthma
    Mark D Eisner
    Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0111, USA
    Immunol Allergy Clin North Am 28:521-37, viii. 2008
    ..This article evaluates the evidence that secondhand smoke exposure is a risk factor for new-onset asthma among adults and exacerbates pre-existing adult asthma, resulting in greater symptom burden and morbidity...
  3. pmc Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol
    Mark D Eisner
    Department of Medicine, University of California, San Francisco, 350 Parnassus Avenue, Suite 609, San Francisco, CA 94117, USA
    Nicotine Tob Res 11:945-53. 2009
    ..Secondhand smoke (SHS) contains respiratory irritants and has the potential to adversely affect adults with chronic obstructive pulmonary disease (COPD), but few studies have evaluated the impact of SHS on COPD...
  4. doi request reprint Secondhand smoke at work
    Mark D Eisner
    University of California, San Francisco, San Francisco, California 94143 0111, USA
    Curr Opin Allergy Clin Immunol 10:121-6. 2010
    ..The present study reviews the recent evidence linking workplace SHS exposure with poor health and the benefits of smoke-free workplace legislation...
  5. pmc Measurement of COPD severity using a survey-based score: validation in a clinically and physiologically characterized cohort
    Mark D Eisner
    University of California San Francisco, 505 Parnassus Ave, M 1097, San Francisco, CA 94143 0111, USA
    Chest 137:846-51. 2010
    ..In this study, we aimed to further validate the severity score in a different COPD cohort and using a combination of patient-reported and objective physiologic measurements...
  6. pmc Directly measured secondhand smoke exposure and COPD health outcomes
    Mark D Eisner
    Department of Medicine, University of California, San Francisco, UCSF Box 0924, San Francisco, CA 94113 0924, USA
    BMC Pulm Med 6:12. 2006
    ..Despite the importance of this question, the impact of SHS exposure on COPD health outcomes remains unknown...
  7. ncbi request reprint Risk factors for work disability in severe adult asthma
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94117, USA
    Am J Med 119:884-91. 2006
    ..We aimed to elucidate the prevalence of and risk factors for work disability in severe adult asthma and to evaluate the impact of work disability on downstream health outcomes...
  8. pmc The impact of SHS exposure on health status and exacerbations among patients with COPD
    Mark D Eisner
    Division of Occupational and Environmental Medicine, University of California, San Francisco, CA 94143 0111, USA
    Int J Chron Obstruct Pulmon Dis 4:169-76. 2009
    ..18 and HR 1.40; 95% CI 0.94 to 2.10, respectively). In conclusion, SHS was associated with poorer health status and a greater risk of COPD exacerbation. COPD patients may comprise a vulnerable population for the health effects of SHS...
  9. pmc Influence of anxiety on health outcomes in COPD
    Mark D Eisner
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA 94143 0111, USA
    Thorax 65:229-34. 2010
    ..To better define the role of anxiety in chronic obstructive pulmonary disease (COPD), a study was conducted of the inter-relations between anxiety and COPD in a large cohort of subjects with COPD and a matched control group...
  10. pmc Body composition and functional limitation in COPD
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, USA
    Respir Res 8:7. 2007
    ..Low body mass index has been associated with increased mortality in severe COPD. The impact of body composition earlier in the disease remains unclear. We studied the impact of body composition on the risk of functional limitation in COPD...
  11. pmc Development of disability in chronic obstructive pulmonary disease: beyond lung function
    Mark D Eisner
    University of California, San Francisco, 505 Parnassus Avenue, M1097, San Francisco, CA 94143 0111, USA
    Thorax 66:108-14. 2011
    ..COPD is a major cause of disability, but little is known about how disability develops in this condition...
  12. pmc Pulmonary function and the risk of functional limitation in chronic obstructive pulmonary disease
    Mark D Eisner
    Division of Occupational and Environmental Medicine and Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA 94117, USA
    Am J Epidemiol 167:1090-101. 2008
    ..Longitudinal follow-up can delineate the impact of these functional limitations on the prospective risk of disability, guiding preventive strategies that could attenuate the disablement process...
  13. pmc COPD as a systemic disease: impact on physical functional limitations
    Mark D Eisner
    Division of Occupational and Environmental Medicine and Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA 94143 0111, USA
    Am J Med 121:789-96. 2008
    ..We aimed to elucidate the physical functional limitations that are directly attributable to COPD compared to a matched referent group without the condition...
  14. pmc Socioeconomic status, race and COPD health outcomes
    M D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0111, USA
    J Epidemiol Community Health 65:26-34. 2011
    ..Although chronic obstructive pulmonary disease (COPD) is a common cause of death and disability, little is known about the effects of socioeconomic status (SES) and race-ethnicity on health outcomes...
  15. pmc Recent trends in acute lung injury mortality: 1996-2005
    Sara E Erickson
    Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, GA, USA
    Crit Care Med 37:1574-9. 2009
    ..We sought to determine whether recent advances in the treatment of ALI and related critical illnesses have resulted in decreased mortality from ALI...
  16. doi request reprint BMI and health status among adults with asthma
    Michael Vortmann
    Division of Occupational and Environmental Medicine and Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, California, USA
    Obesity (Silver Spring) 16:146-52. 2008
    ..A convincing body of literature links obesity with a higher risk for developing adult-onset asthma. The impact of obesity on asthma severity among adults with pre-existing asthma, however, is less clear...
  17. pmc The impact of allergy and pulmonary specialist care on emergency asthma utilization in a large managed care organization
    Sara Erickson
    Department of Medicine, University of California, San Fransisco, 350 Parnassus Avenue, Ste 609, San Francisco, CA 94117, USA
    Health Serv Res 40:1443-65. 2005
    ..To evaluate the longitudinal impact of asthma specialist care on the risk of emergency department (ED) visits and hospitalization for asthma...
  18. pmc Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome
    Lorraine B Ware
    Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Crit Care Med 35:1821-8. 2007
    ..However, direct evidence for the contribution of abnormalities in coagulation and fibrinolysis proteins to outcomes in patients with acute lung injury/acute respiratory distress syndrome is lacking...
  19. ncbi request reprint The influence of perceived control of asthma on health outcomes
    Carolyn S Calfee
    Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94115, USA
    Chest 130:1312-8. 2006
    ..Psychosocial factors play an important role in outcomes of asthma. Perceived control, a measure of patients' beliefs about their ability to control their disease, has not been studied in association with asthma health outcomes..
  20. ncbi request reprint Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury
    Polly E Parsons
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Fletcher Allen Health Care, University of Vermont, Burlington, Vermont 05401, USA
    Am J Physiol Lung Cell Mol Physiol 288:L426-31. 2005
    ..Furthermore, LTVV is associated with a specific decrease in sTNFRI levels. This suggests that one beneficial effect of LTVV may be to attenuate alveolar epithelial injury...
  21. ncbi request reprint Leukotriene modifier use and asthma severity: how is a new medication being used by adults with asthma?
    Laurie Snyder
    Department of Medicine, University of California, San Francisco, 94117, USA
    Arch Intern Med 164:617-22. 2004
    ..Because milder asthma is usually controllable with more familiar medications, we hypothesized that adults with asthma would receive leukotriene modifiers for more severe disease...
  22. ncbi request reprint Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury
    Polly E Parsons
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Fletcher Allen Health Care, University of Vermont, USA
    Crit Care Med 33:1-6; discussion 230-2. 2005
    ....
  23. pmc Risk factors for death in adults with severe asthma
    Theodore A Omachi
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, San Francisco, California 94143 0111, USA
    Ann Allergy Asthma Immunol 101:130-6. 2008
    ..Mortality risk in adult asthma is poorly understood, especially the interplay among race, disease severity, and health care access...
  24. pmc Urine cotinine underestimates exposure to the tobacco-derived lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in passive compared with active smokers
    Neal Benowitz
    Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 1220, USA
    Cancer Epidemiol Biomarkers Prev 19:2795-800. 2010
    ....
  25. pmc Respiratory and skeletal muscle strength in chronic obstructive pulmonary disease: impact on exercise capacity and lower extremity function
    Jonathan Singer
    Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California, San Francisco, California 94143, USA
    J Cardiopulm Rehabil Prev 31:111-9. 2011
    ..We sought to quantify the impact of respiratory muscle and lower extremity strength on exercise capacity and lower extremity function (LEF) in patients with chronic obstructive pulmonary disease (COPD)...
  26. pmc Socioeconomic gradients in tiotropium use among adults with COPD
    Paul D Blanc
    Division of Occupational and Environmental Medicine, Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94143 0924, USA
    Int J Chron Obstruct Pulmon Dis 3:483-90. 2008
    ..Inequalities in the use of new medications may contribute to health disparities. We analyzed socioeconomic gradients in the use of tiotropium for chronic obstructive pulmonary disease (COPD)...
  27. pmc Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate active from passive smoking
    Maciej Lukasz Goniewicz
    Division of Clinical Pharmacology and Experimental Therapeutics, University of California, San Francisco, Box 1220, San Francisco, CA 94143 1220, USA
    Nicotine Tob Res 13:202-8. 2011
    ..The aim of the study was to determine optimal cutoff points to discriminate active versus passive smokers and to compare sensitivity and specificity for the use of cotinine, NNAL, and the ratio of the NNAL/cotinine in urine...
  28. pmc Exposure to traffic: lung function and health status in adults with asthma
    John R Balmes
    Department of Medicine, University of California San Francisco, San Francisco, Calif 94143 0843, USA
    J Allergy Clin Immunol 123:626-31. 2009
    ..Exposure to traffic has been associated with asthma outcomes in children, but its effect on asthma in adults has not been well studied...
  29. pmc Subpicogram per milliliter determination of the tobacco-specific carcinogen metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine using liquid chromatography-tandem mass spectrometry
    Peyton Jacob
    Division of Clinical Pharmacology, University of California, San Francisco, UCSF Box 1220, San Francisco, California 94143 1220, USA
    Anal Chem 80:8115-21. 2008
    ..The lower limit of quantitation is 0.25 pg/mL for 5-mL urine specimens. Applications to studies of people with a range of different SHS exposure levels is described...
  30. pmc The impact of a "low-intensity" versus "high-intensity" medical intensive care unit on patient outcomes in critically ill veterans
    Jonathan P Singer
    Division of Pulmonary Critical Care Medicine, UC San Francisco, CA 94143, USA
    J Intensive Care Med 25:233-9. 2010
    ....
  31. pmc The COPD Helplessness Index: a new tool to measure factors affecting patient self-management
    Theodore A Omachi
    University of California, San Francisco, Box 0111, 505 Parnassus Ave, San Francisco, CA 94143 0111, USA
    Chest 137:823-30. 2010
    ..Psychologic factors affect how patients with COPD respond to attempts to improve their self-management skills. Learned helplessness may be one such factor, but there is no validated measure of helplessness in COPD...
  32. pmc Onset of depressive symptoms among adults with asthma: results from a longitudinal observational cohort
    Patricia P Katz
    Department of Medicine, University of California, San Francisco, California 94143 0936, USA
    Prim Care Respir J 19:223-30. 2010
    ..The study goal was to identify risk factors for depression onset among a community-based sample of adults with asthma...
  33. pmc Further exploration of the links between occupational exposure and chronic obstructive pulmonary disease
    Paul D Blanc
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0924, USA
    J Occup Environ Med 51:804-10. 2009
    ..To examine occupational risk for Chronic Obstructive Pulmonary Disease (COPD)...
  34. pmc Obstructive sleep apnea: a risk factor for work disability
    Theodore A Omachi
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA 94143 0111, USA
    Sleep 32:791-8. 2009
    ..To examine obstructive sleep apnea (OSA) as a risk factor for work disability...
  35. pmc Screening for depression in chronic obstructive pulmonary disease
    Laura J Julian
    Department of Medicine, University of California San Francisco, CA 94143 0920, USA
    COPD 6:452-8. 2009
    ..These results suggest that mood disorders are relatively common among persons with COPD. The GDS-15 is a useful screening measure to identify patients at risk for depression...
  36. pmc The impact of disability on depression among individuals with COPD
    Patricia P Katz
    University of California, San Francisco, 3333 California St, Ste 270, San Francisco, CA 94143 0920, USA
    Chest 137:838-45. 2010
    ..Both disability and depression are common in COPD, but limited information is available on the time-ordered relationship between increases in disability and depression onset...
  37. pmc Depression and health-related quality of life in chronic obstructive pulmonary disease
    Theodore A Omachi
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0111, USA
    Am J Med 122:778.e9-15. 2009
    ..Furthermore, we have an incomplete understanding of how much depression versus respiratory factors contributes to poor health-related quality of life...
  38. pmc Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiency
    Theodore A Omachi
    Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Respir Res 12:35. 2011
    ..Matrix metalloproteinase-9 (MMP-9) may be important in the progression of emphysema, but there have been few longitudinal clinical studies of MMP-9 including pulmonary status and COPD exacerbation outcomes...
  39. pmc Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury
    Carolyn S Calfee
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA, 94143 0111, USA
    Intensive Care Med 35:248-57. 2009
    ....
  40. pmc Randomized clinical trial of activated protein C for the treatment of acute lung injury
    Kathleen D Liu
    Division of Nephrology and Critical Care Medicine, Department of Medicine, Box 0532, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Am J Respir Crit Care Med 178:618-23. 2008
    ..Plasma protein C levels are decreased in patients with acute lung injury and are associated with higher mortality and fewer ventilator-free days...
  41. ncbi request reprint Development and validation of a survey-based COPD severity score
    Mark D Eisner
    Department of Medicine, University of California, San Francisco, 350 Parnassus Ave, Ste 609, San Francisco, CA 94117, USA
    Chest 127:1890-7. 2005
    ..To develop a comprehensive disease-specific COPD severity instrument for survey-based epidemiologic research...
  42. pmc Lifetime environmental tobacco smoke exposure and the risk of chronic obstructive pulmonary disease
    Mark D Eisner
    Department of Medicine, University of California San Francisco, UCSF Box 0924, CA 94113 0924, USA
    Environ Health 4:7. 2005
    ..Although ETS exposure appears to cause asthma in children and adults, its role in causing COPD has received limited attention in epidemiologic studies...
  43. ncbi request reprint Impact of the home indoor environment on adult asthma and rhinitis
    Paul D Blanc
    Department of Medicine, Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94117, USA
    J Occup Environ Med 47:362-72. 2005
    ..We sought to study the combined effects of multiple home indoor environmental exposures in adult asthma and rhinitis...
  44. ncbi request reprint Health-related quality of life in adult rhinitis: the role of perceived control of disease
    Hubert Chen
    Department of Medicine, University of California, San Francisco, CA 94143 0924, USA
    J Allergy Clin Immunol 114:845-50. 2004
    ..Factors affecting health-related quality of life (HRQOL) in adult rhinitis have not been well described...
  45. ncbi request reprint Performance of valued life activities reflected asthma-specific quality of life more than general physical function
    Patricia P Katz
    Department of Medicine, University of California San Francisco, 350 Parnassus Ave, Suite 609, San Francisco, CA 94143 0924, USA
    J Clin Epidemiol 57:259-67. 2004
    ..We examined the prevalence of disability in valued life activities (VLAs) among a group of adults with asthma and the impact of general physical function and performance of VLAs on asthma-specific quality of life (QOL)...
  46. ncbi request reprint Perceived control of asthma and quality of life among adults with asthma
    Patricia P Katz
    Department of Medicine, University of California, San Francisco 94143 0920, USA
    Ann Allergy Asthma Immunol 89:251-8. 2002
    ..Perceived control of certain chronic conditions influences health status outcomes...
  47. ncbi request reprint Environmental tobacco smoke exposure during travel among adults with asthma
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, 94117, USA
    Chest 122:826-8. 2002
    ..In California, state law now prohibits smoking in most public places. We examined the prevalence and short-term health impact of environmental tobacco smoke (ETS) exposure during travel among adults with asthma...
  48. pmc The influence of chronic respiratory conditions on health status and work disability
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, and the Cardiovascular Research Institute, San Francisco, CA 94117, USA
    Am J Public Health 92:1506-13. 2002
    ..This study examined the impact of asthma and chronic obstructive pulmonary disease (COPD) on health status and work disability...
  49. pmc Environmental tobacco smoke exposure and pulmonary function among adults in NHANES III: impact on the general population and adults with current asthma
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, California, USA
    Environ Health Perspect 110:765-70. 2002
    ..19%). In conclusion, ETS exposure is associated with decreased pulmonary function in adult females, especially those with asthma. This analysis should provide further impetus for public policies that promote smoke-free environments...
  50. ncbi request reprint Health-related quality of life and future health care utilization for asthma
    Mark D Eisner
    Department of Medicine, University of California, San Francisco 94117, USA
    Ann Allergy Asthma Immunol 89:46-55. 2002
    ..Although health-related quality of life (HRQL) has been increasingly used as an outcome in asthma, its utility for identifying patients at risk for adverse asthma outcomes has not been established...
  51. ncbi request reprint Impact of depressive symptoms on adult asthma outcomes
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, San Francisco, California 94117, USA
    Ann Allergy Asthma Immunol 94:566-74. 2005
    ..Psychological disorders, including depression, are common in adults with asthma. Although depression is treatable, its impact on longitudinal asthma outcomes is not clear...
  52. pmc Exposure to vapors, gas, dust, or fumes: assessment by a single survey item compared to a detailed exposure battery and a job exposure matrix
    Paul D Blanc
    Department of Medicine, The Division of Occupational and Environmental Medicine, University of California San Francisco, San Francisco, California 94117, USA
    Am J Ind Med 48:110-7. 2005
    ..Occupational exposure assessment often relies upon subject report. We examined the characteristics of self-reported exposure in respondents' longest held job to vapors, gas, dust, or fumes (VGDF) compared to other measures of exposure risk...
  53. ncbi request reprint Intensive care unit admission for asthma: a marker for severe disease
    Mark D Eisner
    Division of Occupational and Environmental Medicine, Department of Medicine, University of California, San Francisco, California 94117, USA
    J Asthma 42:315-23. 2005
    ..We systematically evaluated a method for defining a cohort of adults with severe asthma based on recent intensive care unit admissions for asthma...
  54. pmc Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury
    Kathleen D Liu
    Division of Nephrology, University of California, San Francisco, CA, USA
    Crit Care Med 35:2755-61. 2007
    ..To identify biological and clinical predictors of acute kidney injury in subjects with acute lung injury...
  55. pmc Impact of perceived neighborhood problems on change in asthma-related health outcomes between baseline and follow-up
    Irene H Yen
    Department of Medicine, University of California, San Francisco, 3333 California Street, Suite 335, San Francisco, CA 94143 0856, USA
    Health Place 14:468-77. 2008
    ..34; 95% confidence interval: 1.09-5.00). NP did not predict decline in QOL. Analyses adjusted for demographics, asthma severity, and baseline value of the health outcome...
  56. ncbi request reprint Effect of race on asthma management and outcomes in a large, integrated managed care organization
    Sara E Erickson
    Department of Medicine, University of California, San Francisco, CA 94143, USA
    Arch Intern Med 167:1846-52. 2007
    ..Morbidity from asthma disproportionately affects black people. Whether this excess morbidity is fully explained by differences in asthma severity, access to care, or socioeconomic status (SES) is unknown...
  57. ncbi request reprint The influence of cigarette smoking on adult asthma outcomes
    Mark D Eisner
    Division of Occupational and Environmental Medicine and Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA 94117, USA
    Nicotine Tob Res 9:53-6. 2007
    ..Smoking is a modifiable risk factor for adverse asthma health outcomes. Public health interventions should focus on smoking reduction among adults with asthma...
  58. ncbi request reprint Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome
    Thomas J Nuckton
    Cardiovascular Research Institute, Department of Medicine, University of California, San Francisco 94143 0130, USA
    N Engl J Med 346:1281-6. 2002
    ....
  59. pmc Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury
    Dana E McClintock
    Cardiovascular Research Institute and Division of Occupational and Environmental Medicine, Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, California, USA
    Am J Respir Crit Care Med 175:256-62. 2007
    ..Nitrogen oxide (NO) species are markers for oxidative stress that may be pathogenic in acute lung injury (ALI)...
  60. ncbi request reprint Measuring disease-specific quality of life in obstructive airway disease: validation of a modified version of the airways questionnaire 20
    Hubert Chen
    Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94143 0924, USA
    Chest 129:1644-52. 2006
    ..The Airways Questionnaire 20 (AQ20) is a concise measure of health-related quality of life (HRQL) in obstructive airway disease; however, its original format may underestimate impairment due to the complete cessation of certain activities...
  61. pmc Higher urine desmosine levels are associated with mortality in patients with acute lung injury
    Dana E McClintock
    Cardiovascular Research Institute, University of California, San Francisco, CA 94143 0130, and Pulmonary and Critical Care Unit, Department of Medicine, Massachusetts General Hospital, Boston, USA
    Am J Physiol Lung Cell Mol Physiol 291:L566-71. 2006
    ..These results illustrate the value of evaluating urinary biological markers that may have prognostic and pathogenetic significance in acute lung injury...
  62. pmc Perceived neighborhood problems and quality of life, physical functioning, and depressive symptoms among adults with asthma
    Irene H Yen
    Department of Medicine, University of California San Francisco, 3333 California Street, Suite 335, San Francisco, CA 94143 0856, USA
    Am J Public Health 96:873-9. 2006
    ..We investigated associations between perceived neighborhood problems and quality of life (QOL), physical functioning, and depressive symptoms among adults with asthma...
  63. ncbi request reprint Functioning and psychological status among individuals with COPD
    Patricia P Katz
    Department of Medicine, University of California San Francisco, 3333 California Street, Suite 270, San Francisco, CA, USA
    Qual Life Res 14:1835-43. 2005
    ..We examined the link between functioning and psychological status among persons with chronic obstructive pulmonary disease (COPD), using measures of both general functional status and performance of life activities...
  64. ncbi request reprint Effects of physician-related factors on adult asthma care, health status, and quality of life
    Paul D Blanc
    Division of Occupational and Environmental Medicine, Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco 94117, USA
    Am J Med 114:581-7. 2003
    ....
  65. pmc Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders
    Carolyn S Calfee
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Crit Care Med 35:2243-50. 2007
    ....

Research Grants6

  1. ASTHMA HEALTH OUTCOMES FOLLOWING INTENSIVE CARE
    Mark Eisner; Fiscal Year: 2004
    ..This award will enable Dr. Eisner's continued progression to an independent clinical investigator. ..
  2. Disability and Health Outcomes in COPD
    Mark Eisner; Fiscal Year: 2007
    ..Based on this work, intervention strategies can be designed that target reduction of functional limitation and disability to improve downstream health outcomes. ..