Research Topics
| H EilersSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Transcription factors Sp1 and Sp4 regulate TRPV1 gene expression in rat sensory neuronsCatherine Chu
University of California, San Francisco Department of Anesthesia and Perioperative Care 513 Parnassus Ave, RM, S436, University of California, San Francisco 94143 0427, USA
Mol Pain 7:44. 2011..mRNA encoding Sp1, Sp4 and TRPV1 were quantified by qRT-PCR under conditions of Sp1/Sp4 over-expression or siRNA mediated knockdown in cultured DRG neurons...- Emergent orthotopic liver transplantation for hemorrhage from a giant cavernous hepatic hemangioma: case report and reviewParsia A Vagefi
Division of Transplant Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
J Gastrointest Surg 15:209-14. 2011..The optimal surgical management of symptomatic hepatic hemangiomas remains controversial, with resection, enucleation, and both deceased donor and living donor liver transplantation having been reported... 
Chronic kidney disease: implications for the perioperative periodH Eilers
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0648, USA
Minerva Anestesiol 76:725-36. 2010..Better interventions and diagnostic tools, such as cystatin C, are needed to further improve perioperative morbidity and mortality in patients with CKD...- Clinically important drug interactions with intravenous anaesthetics in older patientsHelge Eilers
Department of Anesthesia and Perioperative Care, University of California at San Francisco, San Francisco, California 94143 0464, USA
Drugs Aging 20:969-80. 2003..We have identified a significant lack of scientific and outcome data and the need for more studies and education... - Opioid-induced respiratory depression: are 5-HT4a receptor agonists the cure?Helge Eilers
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143, USA
Mol Interv 4:197-9. 2004 
Pungent general anesthetics activate transient receptor potential-A1 to produce hyperalgesia and neurogenic bronchoconstrictionHelge Eilers
Department of Anesthesia, University of California, San Francisco, California 94143 0427, USA
Anesthesiology 112:1452-63. 2010..This mechanism may explain the hyperalgesic actions of inhaled anesthetics and their adverse effects in the airways...- Hypothermia and isoflurane similarly inhibit glutamate release evoked by chemical anoxia in rat cortical brain slicesH Eilers
Department of Anesthesia, University of California School of Medicine, San Francisco 94143 0542, USA
Anesthesiology 85:600-7. 1996..The purpose of this study was to determine whether isoflurane reduces glutamate release in hypoxic brain slices, how large this effect is compared to that of hypothermia, and if it is diminished by hyperthermia... - Different effects of volatile anesthetics and polyhalogenated alkanes on depolarization-evoked glutamate release in rat cortical brain slicesH Eilers
Department of Anesthesia and Perioperative Care, University of California San Francisco, 94143 0648, USA
Anesth Analg 88:1168-74. 1999..These findings support the hypothesis that the modulation of excitatory neurotransmission might be responsible, in part, for in vivo anesthetic action... - Recombinant factor VIIa reduces transfusion requirements in liver transplant patients with high MELD scoresC U Niemann
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0648, USA
Transfus Med 16:93-100. 2006..In a selected group of patients with prolonged PT and high MELD score, the prophylactic application of rFVIIa at the start of the OLT may reduce perioperative transfusion requirements... - Increasing the duration of isoflurane anesthesia decreases the minimum alveolar anesthetic concentration in 7-day-old but not in 60-day-old ratsGreg Stratmann
Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, CA 94143, USA
Anesth Analg 109:801-6. 2009..After 15 min of anesthesia in 7-day-old rats, MAC was 3.5% compared with 1.3% at 4 h. We investigated whether kinetic or dynamic factors mediated this decrease... - TRPV1 splice variants: structure and functionMark A Schumacher
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0427, USA
Front Biosci 15:872-82. 2010..Moreover, TRPV1 splice variant subunits may also contribute unique properties of activation such as the detection of hypertonic conditions... - Central venous pressure monitoring during living right donor hepatectomyClaus U Niemann
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0648, USA
Liver Transpl 13:266-71. 2007..CVP monitoring did not appear to reduce blood loss when compared with patients without CVP monitoring. In centers with extensive experience, CVP monitoring may not be necessary in this highly selective patient population... - Abdominal organ transplantationC U Niemann
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0648, USA
Minerva Anestesiol 76:266-75. 2010..However, these disagreements are a reflection of the paucity of adequate data for some of the discussed topics... - Anaphylaxis complicating graft reperfusion during orthotopic liver transplantation: a case reportA Anderson
Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94143, USA
Transplant Proc 42:1967-9. 2010..To our knowledge, this is the first report of anaphylaxis at the time of reperfusion and may provide an explanation for cases of vasoplegic syndrome associated with graft reperfusion... - The rat vanilloid receptor splice variant VR.5'sv blocks TRPV1 activationHelge Eilers
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143 0427, USA
Neuroreport 18:969-73. 2007..5'-splice variant-like-protein expression was detected in dorsal root ganglion. These results support the idea that coexpression of VR.5'sv or a similar variant could result in inhibitory modulation of TRPV1 activation... - The effect of ketamine and nitrous oxide on the human pupillary light reflex during general anesthesiaHelge Eilers
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0648, USA
Auton Neurosci 152:108-14. 2010..These findings present evidence that glutamate NMDA receptor activation is involved in generating the human pupillary light reflex... - Isolation of an mRNA binding protein homologue that is expressed in nociceptorsHelge Eilers
Department of Anesthesia and Perioperative Care, University of California, San Francisco, Box 0427, San Francisco, CA 94143 0427, USA
Eur J Neurosci 20:2283-93. 2004....