Mikala Egeblad

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint New functions for the matrix metalloproteinases in cancer progression
    Mikala Egeblad
    Department of Anatomy, University of California at San Francisco, 94143 0452, USA
    Nat Rev Cancer 2:161-74. 2002
  2. pmc GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model
    Hosein Kouros-Mehr
    Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143 0452, USA
    Cancer Cell 13:141-52. 2008
  3. pmc Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy
    Mikala Egeblad
    Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Dis Model Mech 1:155-67; discussion 165. 2008
  4. ncbi request reprint Coevolution of cancer and stromal cellular responses
    Laurie E Littlepage
    Department of Anatomy, University of California, San Francisco, CA 94143, USA
    Cancer Cell 7:499-500. 2005
  5. pmc Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer
    Megumi Morimoto-Tomita
    Department of Anatomy and the UCSF Comprehensive Cancer Center, University of California, San Francisco, 94143 0452, USA
    Neoplasia 7:1001-10. 2005
  6. pmc Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development
    Mikala Egeblad
    Department of Anatomy, University of California, San Francisco, San Francisco, California 94143 0452, USA
    Dev Dyn 236:1683-93. 2007
  7. pmc Ets2-dependent stromal regulation of mouse mammary tumors
    Albert K Man
    The Burnham Institute, La Jolla, California 92037, USA
    Mol Cell Biol 23:8614-25. 2003
  8. pmc Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth
    Jorma A Maatta
    MediCity Research Laboratory and Department of Medical Biochemistry and Molecular Biology, University of Turku, FIN 20520 Turku, Finland
    Mol Biol Cell 17:67-79. 2006

Collaborators

Detail Information

Publications8

  1. ncbi request reprint New functions for the matrix metalloproteinases in cancer progression
    Mikala Egeblad
    Department of Anatomy, University of California at San Francisco, 94143 0452, USA
    Nat Rev Cancer 2:161-74. 2002
    ..With this knowledge in hand, can we rethink the use of MMP inhibitors in the clinic?..
  2. pmc GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model
    Hosein Kouros-Mehr
    Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143 0452, USA
    Cancer Cell 13:141-52. 2008
    ..Rather, malignant progression occurred with an expanding GATA-3-negative tumor cell population. These data indicate that GATA-3 regulates tumor differentiation and suppresses tumor dissemination in breast cancer...
  3. pmc Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy
    Mikala Egeblad
    Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Dis Model Mech 1:155-67; discussion 165. 2008
    ..The techniques are not limited to investigations in cancer, but could give new insights into cell behavior more broadly in development and disease...
  4. ncbi request reprint Coevolution of cancer and stromal cellular responses
    Laurie E Littlepage
    Department of Anatomy, University of California, San Francisco, CA 94143, USA
    Cancer Cell 7:499-500. 2005
    ..2005) show that carcinoma-associated fibroblasts can promote epithelial tumorigenesis by secreting the chemokine SDF-1alpha (CXCL12). SDF-1alpha stimulates carcinoma cell proliferation and recruitment of endothelial precursor cells...
  5. pmc Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer
    Megumi Morimoto-Tomita
    Department of Anatomy and the UCSF Comprehensive Cancer Center, University of California, San Francisco, 94143 0452, USA
    Neoplasia 7:1001-10. 2005
    ..In support of the possible mechanistic relevance of Sulf-2 upregulation in tumors, purified recombinant Sulf-2 promoted angiogenesis in the chick chorioallantoic membrane assay...
  6. pmc Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development
    Mikala Egeblad
    Department of Anatomy, University of California, San Francisco, San Francisco, California 94143 0452, USA
    Dev Dyn 236:1683-93. 2007
    ..Developmental Dynamics 236:1683-1693, 2007. (c) 2007 Wiley-Liss, Inc...
  7. pmc Ets2-dependent stromal regulation of mouse mammary tumors
    Albert K Man
    The Burnham Institute, La Jolla, California 92037, USA
    Mol Cell Biol 23:8614-25. 2003
    ....
  8. pmc Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth
    Jorma A Maatta
    MediCity Research Laboratory and Department of Medical Biochemistry and Molecular Biology, University of Turku, FIN 20520 Turku, Finland
    Mol Biol Cell 17:67-79. 2006
    ....