Research Topics
| James F X EganSummaryAffiliation: University of Connecticut Health Center Country: USA Publications
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Detail Information
Publications
Distortions of sex ratios at birth in the United States; evidence for prenatal gender selectionJames F X Egan
Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington, CT 06030, USA
Prenat Diagn 31:560-5. 2011..The normal male to female livebirth sex ratio ranges from 1.03 to 1.07. Higher ratios in China, India and Korea reflect prenatal sex selection. We reviewed sex ratios for US births to investigate potential prenatal sex selection...
Multiple gestations: the importance of ultrasoundJames F X Egan
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA
Obstet Gynecol Clin North Am 31:141-58. 2004..The availability of high-resolution ultrasound has significantly im-proved the management of multiple gestations...- Demographic differences in Down syndrome livebirths in the US from 1989 to 2006James F X Egan
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington, CT 06030, USA
Prenat Diagn 31:389-94. 2011..To explore demographic differences in Down syndrome livebirths in the United States... - Absent or shortened nasal bone length and the detection of Down Syndrome in second-trimester fetusesElisa A Gianferrari
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Connecticut Health Center, 114 Woodland Street, Farmington, CT 06105, USA
Obstet Gynecol 109:371-5. 2007..To estimate the accuracy of evaluating nasal bone length, expressed as multiples of the median (MoM), for the detection of Down syndrome in second- trimester fetuses... - Combined second-trimester biochemical and ultrasound screening for Down syndromePeter A Benn
Division of Human Genetics, Department of Pediatrics, University of Connecticut Health Center, Farmington 06030, USA
Obstet Gynecol 100:1168-76. 2002..To evaluate the efficacy of a Down syndrome screening protocol that combines second-trimester maternal serum analytes and the continuous ultrasound measures of nuchal fold thickness and proximal long bone length... - Combined sonographic and biochemical markers for Down syndrome screeningMichael G Pinette
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine, USA
J Ultrasound Med 22:1185-90. 2003..To evaluate the efficacy of fetal nuchal fold thickness and proximal long bone biometric measurements in modifying Down syndrome serum screening risk in a population of women referred for second-trimester sonography... - Down syndrome screening in the United States in 2001 and 2007: a survey of maternal-fetal medicine specialistsYu Ming Victor Fang
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Connecticut School of Medicine, Farmington, CT, USA
Am J Obstet Gynecol 201:97.e1-5. 2009..The purpose of this study was to determine changes in screening and performance of invasive diagnostic procedures for Down syndrome between 2001 and 2007... - Changes in the utilization of prenatal diagnosisPeter A Benn
Division of Human Genetics, Department of Genetics and Developmental Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 6140, USA
Obstet Gynecol 103:1255-60. 2004..To measure the overall effectiveness in actual clinical practice, we analyzed the tests performed by a single cytogenetics laboratory... - Trends in the use of second trimester maternal serum screening from 1991 to 2003Peter A Benn
Division of Human Genetics, Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
Genet Med 7:328-31. 2005..001). CONCLUSION: Increased use of maternal serum screening by older women, use of second trimester ultrasound, and improvements in screening methodology have resulted in sharply reduced numbers of amniocenteses in unaffected pregnancies... - Frequency of echogenic intracardiac focus by race/ethnicity in euploid fetusesAdam F Borgida
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Hartford Hospital, Hartford, CT 06102, USA
J Matern Fetal Neonatal Med 18:65-6. 2005..To determine the frequency of echogenic intracardiac focus (EIF) by race/ethnicity... - The role of second-trimester serum screening in the post-first-trimester screening eraAlireza A Shamshirsaz
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 2947, USA
Clin Lab Med 30:667-76. 2010..However, the most efficacious protocols are based on the combination of first- and second-trimester tests. In this article the advantages and best strategies in providing these sequential screening protocols are discussed... - Incorporation of inhibin-A in second-trimester screening for Down syndromePeter A Benn
Division of Human Genetics, Department of Pediatrics, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 6140, USA
Obstet Gynecol 101:451-4. 2003..To evaluate the efficacy of the second-trimester quadruple test (maternal serum alpha-fetoprotein, unconjugated estriol, human chorionic gonadotropin, and inhibin-A) in prenatal screening for Down syndrome... - Down syndrome births in the United States from 1989 to 2001James F X Egan
Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington, USA
Am J Obstet Gynecol 191:1044-8. 2004..We estimated that Down syndrome live births decreased from 3962 in 1989 to 3654 in 2001. CONCLUSION: Down syndrome live births declined in the US despite an expected increase caused by delayed or extended childbearing... - Stepwise sequential screening for fetal aneuploidyPeter A Benn
Division of Human Genetics, Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, CT, USA
Am J Obstet Gynecol 197:312.e1-5. 2007..The purpose of this study was to evaluate stepwise sequential screening for fetal aneuploidy... - Reproducibility of risk figures in 2nd-trimester maternal serum screening for down syndrome: comparison of 2 laboratoriesPeter A Benn
Division of Human Genetics, Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, CT 06030 6140, USA
Clin Chem 52:2087-94. 2006..Analytical error affects 2nd-trimester maternal serum screening for Down syndrome risk estimation. We analyzed the between-laboratory reproducibility of risk estimates from 2 laboratories... - Antenatal Down syndrome screening in the United States in 2001: a survey of maternal-fetal medicine specialistsJames F X Egan
Division of Maternal Fetal Medicine, Department of Obstetrics, St Francis Hospital and Medical Center, Hartford, Conn, USA
Am J Obstet Gynecol 187:1230-4. 2002..This information calls for a consensus regarding risks that are quoted in Down syndrome counseling... - Use of the genetic sonogram in the United States in 2001 and 2007Yu Ming Victor Fang
Department of Obstetrics and Gynecology, University of Connecticut School of Medicine, Division of Maternal Fetal Medicine, Hartford Hospital, Hartford, CT 06106 USA
J Ultrasound Med 27:1543-8. 2008.... - Determining a cutoff for fetal lung maturity with lamellar body count testingMary Beth Janicki
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Saint Francis Hospital and Medical Center, Hartford, Connecticut 06105, USA
J Matern Fetal Neonatal Med 22:419-22. 2009..A lamellar body count (LBC) >or= 50,000/microl is suggested to document fetal lung maturity (FLM). We sought to determine the LBC threshold for FLM with the Cell-dyn 4000 hematology analyser... - Expected performance of second trimester maternal serum testing followed by a 'genetic sonogram' in screening of fetal Down syndromePeter A Benn
Division of Human Genetics, Department of Genetics and Developmental Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT, USA
Prenat Diagn 28:230-5. 2008..To assess the efficacy of screening for fetal Down syndrome through the sequential provision of second trimester maternal serum tests and fetal ultrasound (the 'genetic sonogram')... - Insulin glargine compared with Neutral Protamine Hagedorn insulin in the treatment of pregnant diabeticsYu Ming Victor Fang
Department of Obstetrics and Gynecology, University of Connecticut School of Medicine, Farmington, Connecticut, USA
J Matern Fetal Neonatal Med 22:249-53. 2009..To compare maternal and neonatal outcomes of pregestational and gestational diabetics treated with insulin glargine versus Neutral Protamine Hagedorn (NPH) insulin... - Variation of fetal humeral length in second-trimester fetuses according to race and ethnicityCarolyn M Zelop
University of Connecticut Health Center, St Francis Hospital and Medical Center, Farmington, Connecticut, USA
J Ultrasound Med 22:691-3. 2003..To determine the influence of race and ethnicity on the expected humeral length based on biparietal diameter measured in second-trimester fetuses... - A comparison of reasons for choosing obstetrician/gynecologist subspecialty trainingYu Ming Victor Fang
University of Connecticut School of Medicine, Division of Maternal Fetal Medicine, Department of Ob Gyn, USA
Conn Med 73:165-70. 2009..The recent increase in the number of fellowship applicants is most likely due to a complex interplay of multiple factors... - The relationship between utilization of prenatal care and Down syndrome live birthsBruce A Morris
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Connecticut School of Medicine, Farmington, CT 06030 2946, USA
J Matern Fetal Neonatal Med 20:307-11. 2007..This study evaluated whether utilization of prenatal care, as measured by the Kessner index, affects the number of Down syndrome live births... - The role of ultrasound in screening for fetal Down syndromeJames F X Egan
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Saint Francis Hospital and Medical Center, 114 Woodland Street, Hartford, CT 06105, USA
Curr Womens Health Rep 2:52-8. 2002..Ultrasound enhances the efficacy of either age or age and the serum screen for the antenatal detection of Down syndrome... - Down syndrome screening using race-specific femur lengthAdam F Borgida
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Connecticut School of Medicine, Farmington, USA
Am J Obstet Gynecol 189:977-9. 2003..CONCLUSION: Using institution-specific FL was more efficient in screening for Down syndrome than published expected FL; race-specific analysis did not improve efficiency... - Use of the mitral valve-tricuspid valve distance as a marker of fetal endocardial cushion defectsAlan D Bolnick
Department of Gynecology and Obstetrics, Division of Maternal-Fetal Medicine, University of Connecticut School of Medicine, Farmington, CT, USA
Am J Obstet Gynecol 191:1483-5. 2004..6%, and a false-positive rate of 0% ( P = .0001). CONCLUSION: The mitral valve-tricuspid valve distance is useful clinically in the detection of endocardial cushion defects in second-trimester fetuses... - The genetic sonogram in second trimester down syndrome screeningJames F X Egan
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Saint Francis Hospital and Medical Center, Hartford, Connecticut 06105, USA
Clin Obstet Gynecol 46:897-908. 2003 - Prevalence of the human papillomavirus in an inner-city indigent population with previously normal Pap testsJoelene Werden
Department of Obstetrics and Gynecology, Hartford Hospital, Hartford, CT 06102, USA
J Low Genit Tract Dis 12:287-92. 2008..To determine the prevalence of human papillomavirus (HPV) in our inner-city indigent population (clinic population) of women with previously normal Pap tests and to identify any associated risk factors... - Characteristics of nulliparous women who would consider cesarean delivery on maternal requestMegan O Schimpf
Department of Obstetrics and Gynecology, Division of Urogynecology, Hartford Hospital University of Connecticut, Hartford, Connecticut, USA
Conn Med 75:207-18. 2011..INTRODUCTION/HYPOTHESIS: To identify factors that influence nulliparous women to choose cesarean delivery on maternal request (CDMR)... - Perinatal and neonatal outcomes of triplet gestations based on placental chorionicityJeffrey V Spencer
University of Connecticut Health Center, Farmington, CT, USA
Am J Perinatol 26:587-90. 2009..Dichorionic triamniotic triplets are at increased risk for earlier deliveries and lower birth weight at delivery compared with trichorionic triamniotic triplets... - The influence of body mass index on pregnancy outcomesJenna E Fiala
Department of Obstetrics and Gynecology, St Francis Hospital and Medical Center, Hartford, Connecticut, USA
Conn Med 70:21-3. 2006..CONCLUSION: A statistically significant increase in rate of operative delivery, hypertension, diabetes and a trend toward higher birth weight are associated with increased maternal BMI... - Reported experiences with prenatal care: is there a difference in patient satisfaction based on racial and ethnic background?Amy M Johnson
Department of Obstetrics and Gynecology, Hartford Hospital, University of Connecticut School of Medcine, USA
Conn Med 76:581-4. 2012..001) and language (24.9% clinic vs 4.9% private, P = 0.004). Race andlanguagewere morelikelyto influence clinic patients' perceptions of the prenatal care received as compared to those seeking care in private practices... - Second trimester prenatal ultrasound and screening for Down syndromePeter A Benn
Prenat Diagn 27:884. 2007 - Variation of fetal nasal bone length in second-trimester fetuses according to race and ethnicityCarolyn M Zelop
Department of Obstetrics and Gynecology, Saint Francis Hospital and Medical Center, 114 Woodland St, Hartford, CT 06105 USA
J Ultrasound Med 24:1487-9. 2005..The purpose of this study was to determine the influence of race and ethnicity on the expected nasal bone length (NBL) based on biparietal diameter (BPD) measured in second-trimester fetuses...