Albert O Edwards

Summary

Affiliation: University of Texas
Country: USA

Publications

  1. ncbi Complement factor H polymorphism and age-related macular degeneration
    Albert O Edwards
    Department of Ophthalmology and McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center UTSWMC, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Science 308:421-4. 2005
  2. pmc Retinal pathology and skin barrier defect in mice carrying a Stargardt disease-3 mutation in elongase of very long chain fatty acids-4
    Anne McMahon
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Mol Vis 13:258-72. 2007
  3. pmc Expression of recombinant protein encoded by LOC387715 in Escherichia coli
    Dequan Chen
    Institute for Retina Research, Presbyterian Hospital, 8210 Walnut Hill Lane, Dallas, TX 75231, USA
    Protein Expr Purif 54:275-82. 2007
  4. ncbi Shape discrimination in age-related macular degeneration
    Yi Zhong Wang
    Retina Foundation of the Southwest, Dallas, Texas 75231, USA
    Invest Ophthalmol Vis Sci 43:2055-62. 2002
  5. doi Toll-like receptor polymorphisms and age-related macular degeneration
    Albert O Edwards
    Department of Ophthalmology, Mayor Clinic, Rochester, MN 55905, USA
    Invest Ophthalmol Vis Sci 49:1652-9. 2008
  6. doi Genetics of age-related macular degeneration
    Albert O Edwards
    Mayo Clinic, Department of Ophthalmology, 200 First Street SW, Rochester, MN 55905, USA
    Adv Exp Med Biol 613:211-9. 2008
  7. doi Persisent ocular hypertension following intravitreal ranibizumab
    Sophie J Bakri
    Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905, USA
    Graefes Arch Clin Exp Ophthalmol 246:955-8. 2008
  8. doi Intraocular inflammation following intravitreal injection of bevacizumab
    Sophie J Bakri
    Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Graefes Arch Clin Exp Ophthalmol 246:779-81. 2008
  9. ncbi IDOCS: intelligent distributed ontology consensus system--the use of machine learning in retinal drusen phenotyping
    George Thomas
    Department of Computer Science, University of Iowa, Iowa City, Iowa, USA
    Invest Ophthalmol Vis Sci 48:2278-84. 2007
  10. ncbi Molecular genetics of AMD and current animal models
    Albert O Edwards
    Department of Ophthalmology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA
    Angiogenesis 10:119-32. 2007

Collaborators

Detail Information

Publications14

  1. ncbi Complement factor H polymorphism and age-related macular degeneration
    Albert O Edwards
    Department of Ophthalmology and McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center UTSWMC, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Science 308:421-4. 2005
    ..Possession of at least one histidine at amino acid position 402 increased the risk of AMD 2.7-fold and may account for 50% of the attributable risk of AMD...
  2. pmc Retinal pathology and skin barrier defect in mice carrying a Stargardt disease-3 mutation in elongase of very long chain fatty acids-4
    Anne McMahon
    Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9057, USA
    Mol Vis 13:258-72. 2007
    ..The goal of this study was to generate and characterize heterozygous and homozygous knockin-mice that carry a human STGD3 pathogenic mutation in the mouse Elovl4 gene...
  3. pmc Expression of recombinant protein encoded by LOC387715 in Escherichia coli
    Dequan Chen
    Institute for Retina Research, Presbyterian Hospital, 8210 Walnut Hill Lane, Dallas, TX 75231, USA
    Protein Expr Purif 54:275-82. 2007
    ..coli was achieved by the synonymous modification of its native ORF cDNA sequence for all the 3 groups of bacterial RCs and the simultaneous elimination of SDLS and RBSCS sequences...
  4. ncbi Shape discrimination in age-related macular degeneration
    Yi Zhong Wang
    Retina Foundation of the Southwest, Dallas, Texas 75231, USA
    Invest Ophthalmol Vis Sci 43:2055-62. 2002
    ..In this study, the ability of patients with age-related macular degeneration (AMD) to perform the shape-discrimination task was examined...
  5. doi Toll-like receptor polymorphisms and age-related macular degeneration
    Albert O Edwards
    Department of Ophthalmology, Mayor Clinic, Rochester, MN 55905, USA
    Invest Ophthalmol Vis Sci 49:1652-9. 2008
    ..The purpose of this study was to determine whether common variation in the 10 human toll-like receptors (TLRs) alters the risk of AMD...
  6. doi Genetics of age-related macular degeneration
    Albert O Edwards
    Mayo Clinic, Department of Ophthalmology, 200 First Street SW, Rochester, MN 55905, USA
    Adv Exp Med Biol 613:211-9. 2008
  7. doi Persisent ocular hypertension following intravitreal ranibizumab
    Sophie J Bakri
    Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905, USA
    Graefes Arch Clin Exp Ophthalmol 246:955-8. 2008
    ..To describe the occurrence of ocular hypertension in four patients following injection of ranibizumab intravitreally...
  8. doi Intraocular inflammation following intravitreal injection of bevacizumab
    Sophie J Bakri
    Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Graefes Arch Clin Exp Ophthalmol 246:779-81. 2008
    ..Failure to recognize an eye with anterior chamber and vitreous cell as sterile inflammation can lead to unnecessary treatment for endophthalmitis...
  9. ncbi IDOCS: intelligent distributed ontology consensus system--the use of machine learning in retinal drusen phenotyping
    George Thomas
    Department of Computer Science, University of Iowa, Iowa City, Iowa, USA
    Invest Ophthalmol Vis Sci 48:2278-84. 2007
    ..To use the power of knowledge acquisition and machine learning in the development of a collaborative computer classification system based on the features of age-related macular degeneration (AMD)...
  10. ncbi Molecular genetics of AMD and current animal models
    Albert O Edwards
    Department of Ophthalmology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA
    Angiogenesis 10:119-32. 2007
    ..No effort has been made to perform a comprehensive citation of all areas of AMD genetics and animal models, but rather a selection of observations and supporting references illustrative of the current state of the field is presented...
  11. ncbi Genetic testing for age-related macular degeneration
    Albert O Edwards
    Ophthalmology 113:509-10. 2006
  12. ncbi Genetic linkage of snowflake vitreoretinal degeneration to chromosome 2q36
    Xiaodong Jiao
    Ophthalmic Genetics and Clinical Services Branch, National Eye Institute, Bethesda, Maryland, USA
    Invest Ophthalmol Vis Sci 45:4498-503. 2004
    ....
  13. pmc Age-related macular degeneration--a genome scan in extended families
    Jacek Majewski
    Laboratory of Statistical Genetics, Rockefeller University, New York, NY, USA
    Am J Hum Genet 73:540-50. 2003
    ..Our study has identified new loci that should be considered in future mapping and mutational analyses of AMD and has strengthened the evidence in support of loci suggested by other studies...
  14. pmc Density of common complex ocular traits in the aging eye: analysis of secondary traits in genome-wide association studies
    Albert O Edwards
    Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, United States of America
    PLoS ONE 3:e2510. 2008
    ....