Christopher K Edlund
Affiliation: University of Southern California
- Snagger: a user-friendly program for incorporating additional information for tagSNP selectionChristopher K Edlund
Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
BMC Bioinformatics 9:174. 2008..Many of these programs do not account for potential reduced genomic coverage resulting from genotyping failures nor do they preferentially select SNPs based on functionality, which may be more likely to be biologically important...
- Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and ShanghaiRoman Corral
Department of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA
Int J Cancer 135:335-47. 2014..A SNP that tags both the XRCC6 and SREBF2 genes strongly modifies the association between bladder cancer risk and smoking. ..
- A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32Wendy Cozen
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
Blood 119:469-75. 2012..In a separate analysis, the DRB1*0701 allele was associated with a decreased risk of NSHL (OR = 0.5, 95% confidence interval = 0.4, 0.7). These data support the importance of the HLA class II region in NSHL etiology...
- A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancerChristopher A Haiman
Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, USA
Nat Genet 43:1210-4. 2011..25, P = 1.1 × 10(-9)), particularly in younger women (<50 years of age) (OR = 1.48, P = 1.9 × 10(-9)). Our results identify a genetic locus associated with estrogen receptor negative breast cancer subtypes in multiple populations...
- Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer riskCeleste Leigh Pearce
Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
Hum Mol Genet 20:2263-72. 2011..25). IGF2 is emerging as an important gene for ovarian cancer; additional genotyping is warranted to further confirm these associations with IGF2 and to narrow down the region harboring the causal SNP...