Steven D Edland
Affiliation: University of California
- NIA-funded Alzheimer centers are more efficient than commercial clinical recruitment sites for conducting secondary prevention trials of dementiaSteven D Edland
Department of Neurosciences, University of California San Diego, La Jolla, CA, USA
Alzheimer Dis Assoc Disord 24:159-64. 2010..Targeted retention efforts and utilization of academic sites could substantively improve the statistical power and validity of future clinical trials of cognitively impaired elderly...
- ADCS Prevention Instrument Project: assessment of instrumental activities of daily living for community-dwelling elderly individuals in dementia prevention clinical trialsDouglas Galasko
Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093 0624, USA
Alzheimer Dis Assoc Disord 20:S152-69. 2006..ADL change during a trial could trigger detailed evaluation or serve as an outcome measure. A brief, easily administered, and reliable ADL rating scale would assist prevention studies...
- Neuroimaging enrichment strategy for secondary prevention trials in Alzheimer diseaseLinda K McEvoy
Department of Radiology, University of California, San Diego, La Jolla, CA 92093 0841, USA
Alzheimer Dis Assoc Disord 24:269-77. 2010..Failure to take into account normal age-related changes risks under-powering trials designed to test disease-modifying properties of potential treatments...
- Determinants of hookah use among high school studentsJoshua R Smith
Department of Family and Preventive Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Nicotine Tob Res 13:565-72. 2011..We examined hookah use initiation, prevalence, cessation, and psychosocial risk factors of hookah use among high school students...
- Increasing hookah use in CaliforniaJoshua R Smith
Joint Doctoral Program, University of California, San Diego, and San Diego State University, San Diego, CA, USA
Am J Public Health 101:1876-9. 2011..Hookah use is increasing in California, especially among young adults, and in 2008 reached the highest prevalence ever reported for both genders...
- Power calculations for clinical trials in Alzheimer's diseaseM Colin Ard
Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093 0948, USA
J Alzheimers Dis 26:369-77. 2011..We review the factors that influence sample size estimates, and discuss outstanding issues relevant to planning longitudinal studies of Alzheimer's disease...
- Computer use among patients with age-related macular degenerationBarbara L Brody
Department of Ophthalmology, UC San Diego School of Medicine, La Jolla, CA 92093 0946, USA
Ophthalmic Epidemiol 19:190-5. 2012..To assess the potential of using telemedicine for expansion of an in-person AMD self-management program, we examined the extent of computer use in a sample of older adults with AMD...
- ADCS Prevention Instrument Project: development of a brief verbal memory test for primary prevention clinical trialsDavid P Salmon
Department of Neurosciences, University of California, San Diego, La Jolla, California 92093 0948, USA
Alzheimer Dis Assoc Disord 20:S139-46. 2006....
- The net effect of alternative allocation ratios on recruitment time and trial costRalitza Vozdolska
Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 92093 0949, USA
Clin Trials 6:126-32. 2009..However, studies with alternative allocation ratios require a larger sample size to maintain statistical power, which may result in a net increase in time required to complete recruitment and a net increase in total trial cost...