Research Topics
Species | Mark H EckmanSummaryAffiliation: University of Cincinnati Country: USA Publications
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Publications
Impact of health literacy on outcomes and effectiveness of an educational intervention in patients with chronic diseasesMark H Eckman
Division of General Internal Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
Patient Educ Couns 87:143-51. 2012..Study impact of health literacy on educational intervention for patients "Living with Coronary Artery Disease."..
The cost-effectiveness of screening for chronic hepatitis B infection in the United StatesMark H Eckman
Division of General Internal Medicine and the Center for Clinical Effectiveness, Ohio, USA
Clin Infect Dis 52:1294-306. 2011..Our objective was to determine whether this screening threshold is cost-effective and whether screening lower-prevalence populations might also be cost-effective...
Moving the tipping point: the decision to anticoagulate patients with atrial fibrillationMark H Eckman
Division of General Internal Medicine and the Center for Clinical Effectiveness, University of Cincinnati, Cincinnati, OH 45267 0535, USA
Circ Cardiovasc Qual Outcomes 4:14-21. 2011..Furthermore, new and potentially safer anticoagulants are on the horizon. Thus, the balance between risk factors for stroke and benefit of anticoagulation may be shifting...
Longitudinal analysis of genitourinary and bowel symptoms in prostate cancer patients following brachytherapyMark H Eckman
Division of General Internal Medicine, Department of Medicine, and Center for Clinical Effectiveness, Cincinnati, Ohio, USA
Am J Clin Oncol 33:1-10. 2010..We present a descriptive, longitudinal analysis of genitourinary and bowel symptoms following treatment in a brachytherapy registry at the University of Cincinnati...
Should we test for CYP2C9 before initiating anticoagulant therapy in patients with atrial fibrillation?Mark H Eckman
Division of General Internal Medicine and Center for Clinical Effectiveness, University of Cincinnati Medical Center, University of Cincinnati MHE, PO Box 670535, Cincinnati, OH 45267 0535, USA
J Gen Intern Med 24:543-9. 2009..Genetic variants of the warfarin sensitivity gene CYP2C9 have been associated with increased bleeding risk during warfarin initiation. Studies also suggest that such patients remain at risk throughout treatment...
Cost-effectiveness of using pharmacogenetic information in warfarin dosing for patients with nonvalvular atrial fibrillationMark H Eckman
University of Cincinnati Medical Center, Cincinnati, OH 45267 0535, USA
Ann Intern Med 150:73-83. 2009..In 2007, the U.S. Food and Drug Administration changed the labeling for warfarin (Coumadin, Bristol-Myers Squibb, Princeton, New Jersey), suggesting that clinicians consider genetic testing before initiating therapy...
Testing for factor V Leiden in patients with pulmonary or venous thromboembolism: a cost-effectiveness analysisMark H Eckman
Division of General Internal Medicine, Center for Clinical Effectiveness, University of Cincinnati, OH 45267 0535, USA
Med Decis Making 22:108-24. 2002..Survivors of venous thromboembolism who have the factor V Leiden mutation have an increased risk of recurrent venous thromboembolism (VTE), but the cost-effectiveness of testing for factor VLeiden has not been assessed...
Patient-specific decision-making for warfarin therapy in nonvalvular atrial fibrillation: how will screening with genetics and imaging help?Mark H Eckman
Division of General Internal Medicine and the Center for Clinical Effectiveness, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0535, USA
Stroke 39:3308-15. 2008..We explore whether screening strategies that include genetic profiling and neuroimaging might improve the safety of chronic anticoagulation for atrial fibrillation by identifying individuals from whom warfarin should be withheld...
"Bridging on the river Kwai": the perioperative management of anticoagulation therapyMark H Eckman
Division of General Internal Medicine and Center for Clinical Effectiveness, University of Cincinnati, Cincinnati, OH 45267-0557, USA
Med Decis Making 25:370-3. 2005
Can patients be anticoagulated after intracerebral hemorrhage? A decision analysisMark H Eckman
Division of General Internal Medicine and the Center for Clinical Effectiveness, University of Cincinnati, Cincinnati, OH, USA
Stroke 34:1710-6. 2003....
Valuation of scleroderma and psoriatic arthritis health states by the general publicDinesh Khanna
Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA
Health Qual Life Outcomes 8:112. 2010..Our objective was to assess health values (utilities) from the general public for health states common to people with PsA and SSc for economic evaluations...
Application of a decision support tool for anticoagulation in patients with non-valvular atrial fibrillationMark L Wess
Division of General Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267 0535, USA
J Gen Intern Med 23:411-7. 2008..The use of a patient-specific computerized decision support tool may aid in closing the knowledge gap regarding the best treatment for a patient...
Cost-effectiveness of prophylactic low molecular weight heparin in pregnant women with a prior history of venous thromboembolismJoseph A Johnston
The Health Services Research and Development Service, Veterans Affairs Medical Center, Cincinnati, Ohio, USA
Am J Med 118:503-14. 2005..The balance of risks and benefits in women with different recurrence risks has not been examined...
Predictors of warfarin use among Ohio medicaid patients with new-onset nonvalvular atrial fibrillationJoseph A Johnston
Veterans Affairs Medical Center, Division of General Internal Medicine, University of Cincinnati Medical Center, University of Cincinnati, Cincinnati, Ohio 45267, USA
Arch Intern Med 163:1705-10. 2003..Despite demonstrated efficacy in stroke prevention, warfarin is underused in patients with atrial fibrillation (AF). Reasons for warfarin nonuse are unclear...
Racial disparities in the filling of warfarin prescriptions for nonvalvular atrial fibrillationDaniel P Schauer
Division of General Internal Medicine, Institute for the Study of Health, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0535, USA
Am J Med Sci 333:67-73. 2007..Our goal was to establish whether there have been racial disparities in the filling of warfarin prescriptions for patients with newly incident nonvalvular atrial fibrillation...
Patient-specific decision modeling to guide the use of drotrecogin alpha (activated) in patients with severe sepsisDaniel P Schauer
Division of General Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH 45267 0535, USA
J Crit Care 23:484-92. 2008..Our objective was to create a decision support tool incorporating patient-specific inputs to estimate the balance between treatment risks and benefits for individual patients with severe sepsis...
Psychosocial risk factors for adverse outcomes in patients with nonvalvular atrial fibrillation receiving warfarinDaniel P Schauer
Division of General Internal Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0535, USA
J Gen Intern Med 20:1114-9. 2005....
Thiopurine S- methyltransferase [corrected] testing in idiopathic pulmonary fibrosis: a pharmacogenetic cost-effectiveness analysisJared T Hagaman
Department of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, 231 Albert Sabin Way ML 0564, Cincinnati, OH 45267, USA
Lung 188:125-32. 2010..quot; At prevalence rates lower than our base case, it was not. TPMT testing before initiating therapy with azathioprine, NAC, and steroids is a cost-effective treatment strategy for IPF...
Use of regression modeling to simulate patient-specific decision analysis for patients with nonvalvular atrial fibrillationJoseph A Johnston
University of Cincinnati Medical Center, Ohio, USA
Med Decis Making 23:361-8. 2003..To create a Web-based decision support tool that uses a simple regression equation to simulate performance of patient-specific decision analysis (PSDA) for patients with nonvalvular atrial fibrillation...
A randomized study of scleroderma health state values: a picture is worth a thousand words, and quite a few utiles. [corrected]Dinesh Khanna
Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
Med Decis Making 29:7-14. 2009..We assess utilities from the general public for health states common in scleroderma (SSc) by describing the health states in writing alone v. with photographs of patients with SSc...
Decision modeling to estimate the impact of gastric bypass surgery on life expectancy for the treatment of morbid obesityDaniel P Schauer
University of Cincinnati Medical Center, Medical Center, Cincinnati, OH 45267 0535, USA
Arch Surg 145:57-62. 2010..To create a decision analytic model to estimate the balance between treatment risks and benefits for patients with morbid obesity...
Cost-effectiveness analysis of ED decision making in patients with non-high-risk heart failureSean P Collins
Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH 45267, USA
Am J Emerg Med 27:293-302. 2009..The ED disposition of patients with non-high-risk acute decompensated heart failure (ADHF) is challenging. To help address this problem, we investigated the cost-effectiveness of different ED disposition strategies...
Understanding preferences for disclosure of individual biomarker results among participants in a longitudinal birth cohortStephen E Wilson
Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA
J Med Ethics 36:736-40. 2010..To describe the preferences for disclosure of individual biomarker results among mothers participating in a longitudinal birth cohort...
Cost-effectiveness of telemetry for hospitalized patients with low-risk chest painMichael J Ward
Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
Acad Emerg Med 18:279-86. 2011..Despite a low incidence of cardiac events, limited telemetry availability, and its questionable benefit, these patients are routinely admitted to a monitored setting...
Screening for the risk for bleeding or thrombosisMark H Eckman
Division of General Internal Medicine, University of Cincinnati Medical Center, PO Box 670535, 231 Albert Sabin Way, Cincinnati, OH 45267-0535, USA
Ann Intern Med 138:W15-24. 2003..Routine testing after a first episode of venous thromboembolism is not recommended for most patients...
Cost-effectiveness of interferon gamma release assays vs tuberculin skin tests in health care workersMarie A de Perio
Division of Infectious Diseases, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Box 670560, Cincinnati, OH 45267, USA
Arch Intern Med 169:179-87. 2009..We compared the cost-effectiveness of the QFT-G, QFT-GIT, and TST for detecting LTBI in new health care workers (HCWs)...
Early versus delayed bilateral subthalamic deep brain stimulation for parkinson's disease: a decision analysisAlberto J Espay
Department of Neurology, Movement Disorders Center, The Neuroscience Institute, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
Mov Disord 25:1456-63. 2010..These findings support further evaluation of early STN DBS in a controlled clinical trial...
Health values of adolescents with cystic fibrosisMichael S Yi
Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati Children's Hospital, Cincinnati; Ohio 45267-0535, USA
J Pediatr 142:133-40. 2003..Therefore, health values should be ascertained directly from adolescents...
Cost effectiveness of recombinant factor VIIa for treatment of intracerebral hemorrhageBrett M Kissela
Department of Neurology, University of Cincinnati, 260 Stetson Street, Suite 2300, Cincinnati, Ohio 45267 05525, USA
BMC Neurol 8:17. 2008..We hypothesized that rFVIIa would have a low marginal cost-effectiveness ratio (mCER) given the poor neurologic outcomes after ICH with conventional management...
Underuse of controller medications among children with persistent asthma in the Ohio medicaid population: evolving differences with new medicationsStephen E Wilson
Division of General Internal Medicine, Department of Internal Medicine, College of Medicine, University of Cincinnati, Ohio, USA
Ambul Pediatr 5:83-9. 2005..Despite innovations in asthma care, morbidity and mortality have increased significantly. Underuse of controller medications is a major contributor to increased morbidity and mortality...
Provisional vs. complex stenting strategy for coronary bifurcation lesions: meta-analysis of randomized trialsAbdul Hakeem
Division of Cardiovascular Diseases, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
J Invasive Cardiol 21:589-95. 2009..To assess the optimal percutaneous coronary intervention (PCI) approach for coronary artery bifurcation lesions (CBL), we conducted a meta-analysis of randomized trials comparing provisional stenting (PS) to complex stenting strategy (CS)...
The impact of expected HIV transmission rates on the effectiveness and cost of ruling out HIV infection in infantsJoseph M Mrus
Division of General Internal Medicine, University of Cincinnati Medical Center, P O Box 670535, Cincinnati, OH 45267 0535, USA
Med Decis Making 22:S38-44. 2002..To quantify the costs and effectiveness of different strategies for ruling out HIV infection in infants born to HIV-infected mothers in the United States...
Outcomes of hemodialysis patients in a long-term care hospital setting: a single-center studyCharuhas V Thakar
Cincinnati VA Medical Center, Cincinnati, OH, USA
Am J Kidney Dis 55:300-6. 2010..Outcomes of hemodialysis patients admitted to LTCHs, which includes patients with either end-stage renal disease (ESRD) or acute kidney injury (AKI) requiring dialysis therapy, are not known...
The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhageJonathan Rosand
Neurology Clinical Trials Unit, Department of Neurology, Massachusetts General Hospital, 15 Parkman Street, Boston, MA 02114, USA
Arch Intern Med 164:880-4. 2004..The data suggest that careful control of the INR, already known to limit the risk of warfarin-related ICH, may also limit its severity...
Radioiodine or surgery for toxic thyroid adenoma: dissecting an important decision. A cost-effectiveness analysisGwenaelle M Vidal-Trecan
Departement de sante publique, CHU Cochin Port Royal, Assistance Publique Hopitaux de Paris, Universite Rene Descartes, Paris, France
Thyroid 14:933-45. 2004..To examine the cost effectiveness of therapeutic strategies for toxic thyroid adenoma...
Presidential reflections on the 25th anniversary of the society for medical decision makingArthur S Elstein
Department of Medical Education, University of Illinois at Chicago, USA
Med Decis Making 24:408-20. 2004
