Lynn E Eberly

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Clinical, demographic and laboratory parameters at HAART initiation associated with decreased post-HAART survival in a U.S. military prospective HIV cohort
    Alan R Lifson
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    AIDS Res Ther 9:4. 2012
  2. ncbi request reprint Kaposi's sarcoma and central nervous system disease: a real association or an artifact of the control group? Terry Beirn Community Programs for Clinical Research on AIDS
    L E Eberly
    Community Programs for Clinical Research on AIDS Statistical and Data Management Center, Division of Biostatistics, University of Minnesota, Minneapolis 55455 0378, USA
    AIDS 14:995-1000. 2000
  3. ncbi request reprint Impact of incident diabetes and incident nonfatal cardiovascular disease on 18-year mortality: the multiple risk factor intervention trial experience
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455 0378, USA
    Diabetes Care 26:848-54. 2003
  4. ncbi request reprint Relation of triglyceride levels, fasting and nonfasting, to fatal and nonfatal coronary heart disease
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware Street SE, MMC 303, Minneapolis, MN 55455 0378, USA
    Arch Intern Med 163:1077-83. 2003
  5. ncbi request reprint Metabolic syndrome: risk factor distribution and 18-year mortality in the multiple risk factor intervention trial
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware St, SE, MMC 303, Minneapolis, Minnesota 55455 0378, USA
    Diabetes Care 29:123-30. 2006
  6. ncbi request reprint Multiple-stage screening and mortality in the Multiple Risk Factor Intervention Trial
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware Street SE, MMC 303, Minneapolis, MN 55455 0378, USA
    Clin Trials 1:148-61. 2004
  7. ncbi request reprint Consequences of event rate heterogeneity across non-randomized study sub-groups
    Lynn E Eberly
    University of Minnesota, 420 Delaware St SE, MMC 303, Minneapolis 55455, USA
    Stat Med 23:2023-36. 2004
  8. pmc Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status
    GULIN OZ
    Center for MR Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Mov Disord 25:1253-61. 2010
  9. ncbi request reprint ZIP-code-based versus tract-based income measures as long-term risk-adjusted mortality predictors
    Avis J Thomas
    Coordinating Centers for Biometric Research, Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55414, USA
    Am J Epidemiol 164:586-90. 2006
  10. pmc Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1
    Uzay E Emir
    Department of Radiology, Medical School, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA
    J Neurochem 127:660-8. 2013

Detail Information

Publications47

  1. pmc Clinical, demographic and laboratory parameters at HAART initiation associated with decreased post-HAART survival in a U.S. military prospective HIV cohort
    Alan R Lifson
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    AIDS Res Ther 9:4. 2012
    ..Although highly active antiretroviral therapy (HAART) has improved HIV survival, some patients receiving therapy are still dying. This analysis was conducted to identify factors associated with increased risk of post-HAART mortality...
  2. ncbi request reprint Kaposi's sarcoma and central nervous system disease: a real association or an artifact of the control group? Terry Beirn Community Programs for Clinical Research on AIDS
    L E Eberly
    Community Programs for Clinical Research on AIDS Statistical and Data Management Center, Division of Biostatistics, University of Minnesota, Minneapolis 55455 0378, USA
    AIDS 14:995-1000. 2000
    ..To test the hypothesis that Kaposi's sarcoma (KS) protects against four central nervous system (CNS) diseases in HIV-1-infected individuals...
  3. ncbi request reprint Impact of incident diabetes and incident nonfatal cardiovascular disease on 18-year mortality: the multiple risk factor intervention trial experience
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455 0378, USA
    Diabetes Care 26:848-54. 2003
    ..To report long-term risks for total, cardiovascular disease (CVD), and coronary heart disease (CHD) mortality associated with incident diabetes (using current diagnostic criteria) and with incident nonfatal CVD (NF-CVD)...
  4. ncbi request reprint Relation of triglyceride levels, fasting and nonfasting, to fatal and nonfatal coronary heart disease
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware Street SE, MMC 303, Minneapolis, MN 55455 0378, USA
    Arch Intern Med 163:1077-83. 2003
    ..It remains unclear whether hypertriglyceridemia is an independent risk factor for coronary heart disease (CHD), and whether fasting and nonfasting triglyceride (TG) levels are equally predictive...
  5. ncbi request reprint Metabolic syndrome: risk factor distribution and 18-year mortality in the multiple risk factor intervention trial
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware St, SE, MMC 303, Minneapolis, Minnesota 55455 0378, USA
    Diabetes Care 29:123-30. 2006
    ..To examine the long-term association of metabolic syndrome with mortality among those at high risk for cardiovascular disease (CVD)...
  6. ncbi request reprint Multiple-stage screening and mortality in the Multiple Risk Factor Intervention Trial
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware Street SE, MMC 303, Minneapolis, MN 55455 0378, USA
    Clin Trials 1:148-61. 2004
    ..9 years was substantially lower than projected during design. We explore factors which may have contributed to these mortality differences and whether they persisted throughout follow-up...
  7. ncbi request reprint Consequences of event rate heterogeneity across non-randomized study sub-groups
    Lynn E Eberly
    University of Minnesota, 420 Delaware St SE, MMC 303, Minneapolis 55455, USA
    Stat Med 23:2023-36. 2004
    ..When the groups are not significantly different, but heterogeneity differs between them, an analysis ignoring the heterogeneity can even result in a significant negative comparison...
  8. pmc Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status
    GULIN OZ
    Center for MR Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Mov Disord 25:1253-61. 2010
    ..These data demonstrate that (1)H MRS biomarkers can be utilized to noninvasively assess neuronal and glial status in individual ataxia patients...
  9. ncbi request reprint ZIP-code-based versus tract-based income measures as long-term risk-adjusted mortality predictors
    Avis J Thomas
    Coordinating Centers for Biometric Research, Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55414, USA
    Am J Epidemiol 164:586-90. 2006
    ..These patterns held across various causes of death, for both Blacks and non-Blacks, and with or without adjustment for ZIP-code-based income diversity or tract-based proportion below poverty...
  10. pmc Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1
    Uzay E Emir
    Department of Radiology, Medical School, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA
    J Neurochem 127:660-8. 2013
    ..Very early neurochemical alterations were detectable prior to overt pathology in the volume-of-interest for MRS. Alterations were indicative of osmolytic changes and of disturbances in membrane phospholipid and energy metabolism. ..
  11. pmc In vivo monitoring of recovery from neurodegeneration in conditional transgenic SCA1 mice
    GULIN OZ
    Center for Magnetic Resonance Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, MN 55455, USA
    Exp Neurol 232:290-8. 2011
    ..Therefore this study presents an important step in validating MRS biomarkers as potential surrogate markers to evaluate therapeutics in pre-clinical and clinical trials in SCA1...
  12. ncbi request reprint Ginkgo biloba use in nursing home elderly with epilepsy or seizure disorder
    Susan L Harms
    Division of Health Services Research and Policy, School of Public Health, 420 Delaware Street SE, MMC 729, Minneapolis, MN 55455, U S A
    Epilepsia 47:323-9. 2006
    ....
  13. pmc Neurochemical profile of patients with type 1 diabetes measured by ¹H-MRS at 4 T
    Silvia Mangia
    Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Cereb Blood Flow Metab 33:754-9. 2013
    ..No other differences in metabolites were observed between subjects with T1DM and controls...
  14. ncbi request reprint Use of antiepileptic medications in nursing homes
    Judith Garrard
    Division of Health Policy and Management, School of Public Health University of Minnesota, Minneapolis, Minnesota 55455, USA
    Int Rev Neurobiol 81:165-82. 2007
    ..Manic depression (bipolar disease) was also significantly associated with initiation of an AED after admission. In this group, there was an inverse relationship between age and initiation of an AED...
  15. pmc Estimated plasma stearoyl co-A desaturase-1 activity and risk of incident diabetes: the Atherosclerosis Risk in Communities (ARIC) study
    Lisa S Chow
    Department of Medicine, University of Minnesota, Minneapolis, MN, USA
    Metabolism 62:100-8. 2013
    ..Translation of these findings to humans remains less defined. The purpose of this research was to evaluate the association between different measures of SCD-1 activity and incident diabetes in a large, prospective human study...
  16. pmc Race/ethnicity, income, major risk factors, and cardiovascular disease mortality
    Avis J Thomas
    Coordinating Centers for Biometric Research, University of Minnesota, 2221 University Ave SE, Suite 200, Minneapolis, MN 55414, USA
    Am J Public Health 95:1417-23. 2005
    ..We explored differences between Black and White men for cardiovascular disease (CVD) mortality across major risk factor levels...
  17. pmc Changes in human brain glutamate concentration during hypoglycemia: insights into cerebral adaptations in hypoglycemia-associated autonomic failure in type 1 diabetes
    Melissa Terpstra
    Center for Magnetic Resonance Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota, USA
    J Cereb Blood Flow Metab 34:876-82. 2014
    ..In an exploratory analysis, we detected additional metabolite changes in response to hypoglycemia in the T1D patient without HAAF control group, namely, increased aspartate and decreased lactate. ..
  18. pmc Hypoglycemia-induced increases in thalamic cerebral blood flow are blunted in subjects with type 1 diabetes and hypoglycemia unawareness
    Silvia Mangia
    Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Cereb Blood Flow Metab 32:2084-90. 2012
    ..A positive correlation was observed between thalamic response and epinephrine response to hypoglycemia, suggesting that this region may be involved in the coordination of the counter regulatory response to hypoglycemia...
  19. ncbi request reprint Latino risk-adjusted mortality in the men screened for the Multiple Risk Factor Intervention Trial
    Avis J Thomas
    Coordinating Centers for Biometric Research, Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55414, USA
    Am J Epidemiol 162:569-78. 2005
    ..Results were not likely an artifact of return migration or incomplete mortality data...
  20. ncbi request reprint The association of physical activity with lung cancer incidence in a cohort of older women: the Iowa Women's Health Study
    Penny Sinner
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Cancer Epidemiol Biomarkers Prev 15:2359-63. 2006
    ..We examined the potential association between physical activity and lung cancer in women...
  21. pmc Prevalence of incontinence by race and ethnicity of older people admitted to nursing homes
    Donna Z Bliss
    University of Minnesota School of Nursing, Minneapolis, MN 55455, USA
    J Am Med Dir Assoc 14:451.e1-7. 2013
    ..The purpose of this study was to describe the prevalence of incontinence among older adults admitted to NHs by race/ethnicity at three levels of measurement: individual resident, NH, and Census division...
  22. ncbi request reprint Prevalence of appropriate and problematic antiepileptic combination therapy in older people in the nursing home
    Susan L Harms
    Division of Health Services Research and Policy, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Am Geriatr Soc 53:1023-8. 2005
    ....
  23. ncbi request reprint Longitudinal evaluation of allergen and culturable fungal concentrations in inner-city households
    Sook Ja Cho
    Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
    J Occup Environ Hyg 5:107-18. 2008
    ..Total culturable fungi will require greater than nine repeated measurements for robust assessment of long-term exposures because of low correlations in fungal measures over time...
  24. doi request reprint Comparing exposure zones by different exposure metrics using statistical parameters: contrast and precision
    Ji Young Park
    University of Minnesota, Minneapolis, 55455, USA
    Ann Occup Hyg 54:799-812. 2010
    ..Because the choice of an exposure metric has significant implications for epidemiologic studies and industrial hygiene practice, a multimetric sampling approach is recommended for nanoparticle exposure assessment...
  25. ncbi request reprint Personal, indoor, and outdoor VOC exposures in a probability sample of children
    John L Adgate
    Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis, MN 55455, USA
    J Expo Anal Environ Epidemiol 14:S4-S13. 2004
    ..There are relatively little data on VOC exposures in children, so these results are useful for estimating the central tendency and distribution of VOC exposures in locations where children spend a majority of their time...
  26. pmc Predicting children's short-term exposure to pesticides: results of a questionnaire screening approach
    Ken Sexton
    Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
    Environ Health Perspect 111:123-8. 2003
    ..Results indicate that the residential pesticide-use questions and overall screening approach used in the MNCPES were ineffective for identifying and oversampling children/households with higher levels of individual target pesticides...
  27. ncbi request reprint Antiepileptic drug use in nursing home admissions
    Judith Garrard
    Division of Health Services Research and Policy, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
    Ann Neurol 54:75-85. 2003
    ..Results also show that the rate of AED use in nursing homes is not static...
  28. ncbi request reprint Variations in product choices of frequently purchased herbs: caveat emptor
    Judith Garrard
    Divisions of Health Services Research and Policy, School of Public Health, and College of Pharmacy, University of Minnesota, Minneapolis 55455, USA
    Arch Intern Med 163:2290-5. 2003
    ..The purpose of this study was to describe variations in label information of products for each of the 10 most commonly purchased herbs...
  29. pmc Human brain glycogen metabolism during and after hypoglycemia
    GULIN OZ
    Center for MR Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota, USA
    Diabetes 58:1978-85. 2009
    ..We tested the hypotheses that human brain glycogen is mobilized during hypoglycemia and its content increases above normal levels ("supercompensates") after hypoglycemia...
  30. pmc Neurochemical changes in the rat prefrontal cortex following acute phencyclidine treatment: an in vivo localized (1)H MRS study
    Isabelle Iltis
    Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, 55455, USA
    NMR Biomed 22:737-44. 2009
    ..MRS studies of this pharmacological rat model may be useful for assessing the effects of potential anti-psychotic drugs in vivo...
  31. doi request reprint Body size and predatory performance in wolves: is bigger better?
    Daniel R MacNulty
    Department of Ecology, Evolution and Behaviour, University of Minnesota, 1987 Upper Buford Circle, St Paul, MN 55108, USA
    J Anim Ecol 78:532-9. 2009
    ..We argue that this could potentially narrow the dietary niche of larger carnivores as well as limit the evolution of larger size if prey are substantially more difficult to pursue than to handle...
  32. ncbi request reprint Agreement of pesticide biomarkers between morning void and 24-h urine samples from farmers and their children
    Deanna P Scher
    Environmental Health Sciences Division, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
    J Expo Sci Environ Epidemiol 17:350-7. 2007
    ..g., farm families), the pharmacokinetics of the pesticide and the timing of exposure events and urine collection must be understood when relying on single voids as a surrogate for longer time-frames of exposure...
  33. ncbi request reprint Training status diverges muscle diacylglycerol accumulation during free fatty acid elevation
    Lisa S Chow
    Department of Medicine, University of Minnesota, Minneapolis, Minnesota
    Am J Physiol Endocrinol Metab 307:E124-31. 2014
    ....
  34. pmc Brain glycogen content and metabolism in subjects with type 1 diabetes and hypoglycemia unawareness
    GULIN OZ
    Department of Radiology, Center for Magnetic Resonance Research, Medical School, University of Minnesota, Minneapolis, Minnesota, USA
    J Cereb Blood Flow Metab 32:256-63. 2012
    ..Metabolic modeling indicated lower brain glycogen content in patients than in controls (P=0.07), implying that glycogen supercompensation does not contribute to the development of hypoglycemia unawareness in humans with type 1 diabetes...
  35. pmc Impulsive behavior and associated clinical variables in Parkinson's disease
    Aviva Abosch
    Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA
    Psychosomatics 52:41-7. 2011
    ..Parkinson's disease (PD) is a degenerative brain disorder accompanied by the loss of dopaminergic neurons and the presence of motor and non-motor symptoms...
  36. pmc (1)H MR spectroscopy in Friedreich's ataxia and ataxia with oculomotor apraxia type 2
    Isabelle Iltis
    Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN 55455, USA
    Brain Res 1358:200-10. 2010
    ..We aimed at assessing the neurochemical profile of the pons, the cerebellar hemisphere and the vermis in patients with FRDA and AOA2 to identify potential biomarkers of these diseases...
  37. ncbi request reprint Multiple linear regression
    Lynn E Eberly
    Division of Biostatistics, University of Minnesota, Minneapolis, MN, USA
    Methods Mol Biol 404:165-87. 2007
    ..The special cases of regression with interactions among the variables, polynomial regression, regressions with categorical (grouping) variables, and separate slopes models are also covered. Examples in microbiology are used throughout...
  38. pmc Influence of foot orientation on the appearance and quantification of 1H magnetic resonance muscle spectra obtained from the soleus and the vastus lateralis
    Małgorzata Marjańska
    Center for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Magn Reson Med 68:1731-7. 2012
    ..It was concluded that quantifying intramyocellular lipid by the standard LCModel using a water reference may be more appropriate than using a creatine reference in the presence of residual dipolar couplings...
  39. pmc Acute free fatty acid elevation eliminates endurance training effect on insulin sensitivity
    Lisa S Chow
    Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Clin Endocrinol Metab 97:2890-7. 2012
    ..Both training and normal body mass index are associated with high insulin sensitivity, but the mechanism may be different...
  40. ncbi request reprint Pulmonary function as a predictor of lung cancer mortality in continuing cigarette smokers and in quitters
    Lynn E Eberly
    Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Int J Epidemiol 32:592-9. 2003
    ..We examined the association of FEV(1) with lung cancer mortality (LCM) among cigarette smokers in the Multiple Risk Factor Intervention Trial (MRFIT)...
  41. ncbi request reprint Variation in deep brain stimulation electrode impedance over years following electrode implantation
    David Satzer
    Department of Neurosurgery, University of Minnesota, Minneapolis, Minn, USA
    Stereotact Funct Neurosurg 92:94-102. 2014
    ..Deep brain stimulation (DBS) electrode impedance is a major determinant of current delivery to target tissues, but long-term variation in impedance has received little attention...
  42. doi request reprint Ninety-day mortality after intertrochanteric hip fracture: does provider volume matter?
    Mary L Forte
    University of Minnesota, Minneapolis, Minnesota, USA
    J Bone Joint Surg Am 92:799-806. 2010
    ..This study examined the association between surgeon and hospital volumes of procedures performed for the treatment of intertrochanteric hip fractures in Medicare beneficiaries and inpatient through ninety-day postoperative mortality...
  43. pmc Noninvasive detection of presymptomatic and progressive neurodegeneration in a mouse model of spinocerebellar ataxia type 1
    GULIN OZ
    Center for Magnetic Resonance Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Neurosci 30:3831-8. 2010
    ..These data demonstrate that presymptomatic and progressive neurodegeneration in SCA1 can be noninvasively monitored using MRS...
  44. ncbi request reprint Correlation and simple linear regression
    Lynn E Eberly
    Division of Biostatistics, University of Minnesota, Minneapolis, MN, USA
    Methods Mol Biol 404:143-64. 2007
    ..This chapter provides a framework that is helpful in understanding more complex statistical techniques, such as multiple linear regression, linear mixed effects models, logistic regression, and proportional hazards regression...
  45. ncbi request reprint GEE estimation of a misspecified time-varying covariate: an example with the effect of alcoholism treatment on medical utilization
    Melanie M Wall
    Division of Biostatistics, School of Public Health at the University of Minnesota, Minneapolis, MN 55455, USA
    Stat Med 24:925-39. 2005
    ..A simulation study is performed to demonstrate that misspecification of the time-varying covariate in the marginal mean structure can cause differences in GEE results across various choices of working correlation structure...
  46. pmc Associations of smoking prevalence with individual and area level social cohesion
    Joan M Patterson
    University of Minnesota School of Public Health, Minneapolis, USA
    J Epidemiol Community Health 58:692-7. 2004
    ..To discover if area level social cohesion, neighbourhood safety, and home safety are associated with current cigarette smoking among adults after adjustment for concentrations of poverty and low education...
  47. ncbi request reprint Sex differences in learning in chimpanzees
    Elizabeth V Lonsdorf
    Department of Ecology, Evolution and Behavior, University of Minnesota, Saint Paul, Minnesota 55108, USA
    Nature 428:715-6. 2004
    ..We find that there are distinct sex-based differences, akin to those found in human children, in the way in which young chimpanzees develop their termite-fishing skills...