Research Topics
Species | Lynn E EberlySummaryAffiliation: University of Minnesota Country: USA Publications
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Publications
Kaposi's sarcoma and central nervous system disease: a real association or an artifact of the control group? Terry Beirn Community Programs for Clinical Research on AIDSL E Eberly
Community Programs for Clinical Research on AIDS Statistical and Data Management Center, Division of Biostatistics, University of Minnesota, Minneapolis 55455 0378, USA
AIDS 14:995-1000. 2000..This was an observational study...- Consequences of event rate heterogeneity across non-randomized study sub-groupsLynn E Eberly
University of Minnesota, 420 Delaware St SE, MMC 303, Minneapolis 55455, USA
Stat Med 23:2023-36. 2004..When the groups are not significantly different, but heterogeneity differs between them, an analysis ignoring the heterogeneity can even result in a significant negative comparison... - Multiple-stage screening and mortality in the Multiple Risk Factor Intervention TrialLynn E Eberly
Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware Street SE, MMC 303, Minneapolis, MN 55455 0378, USA
Clin Trials 1:148-61. 2004..9 years was substantially lower than projected during design. We explore factors which may have contributed to these mortality differences and whether they persisted throughout follow-up... - Metabolic syndrome: risk factor distribution and 18-year mortality in the multiple risk factor intervention trialLynn E Eberly
Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware St, SE, MMC 303, Minneapolis, Minnesota 55455 0378, USA
Diabetes Care 29:123-30. 2006..To examine the long-term association of metabolic syndrome with mortality among those at high risk for cardiovascular disease (CVD)... - Relation of triglyceride levels, fasting and nonfasting, to fatal and nonfatal coronary heart diseaseLynn E Eberly
Division of Biostatistics, School of Public Health, University of Minnesota, 420 Delaware Street SE, MMC 303, Minneapolis, MN 55455 0378, USA
Arch Intern Med 163:1077-83. 2003..It remains unclear whether hypertriglyceridemia is an independent risk factor for coronary heart disease (CHD), and whether fasting and nonfasting triglyceride (TG) levels are equally predictive... - Impact of incident diabetes and incident nonfatal cardiovascular disease on 18-year mortality: the multiple risk factor intervention trial experienceLynn E Eberly
Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455 0378, USA
Diabetes Care 26:848-54. 2003..To report long-term risks for total, cardiovascular disease (CVD), and coronary heart disease (CHD) mortality associated with incident diabetes (using current diagnostic criteria) and with incident nonfatal CVD (NF-CVD)... 
Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical statusGULIN OZ
Center for MR Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA
Mov Disord 25:1253-61. 2010..These data demonstrate that (1)H MRS biomarkers can be utilized to noninvasively assess neuronal and glial status in individual ataxia patients...- ZIP-code-based versus tract-based income measures as long-term risk-adjusted mortality predictorsAvis J Thomas
Coordinating Centers for Biometric Research, Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55414, USA
Am J Epidemiol 164:586-90. 2006..These patterns held across various causes of death, for both Blacks and non-Blacks, and with or without adjustment for ZIP-code-based income diversity or tract-based proportion below poverty... - In vivo monitoring of recovery from neurodegeneration in conditional transgenic SCA1 miceGULIN OZ
Center for Magnetic Resonance Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, MN 55455, USA
Exp Neurol 232:290-8. 2011..Therefore this study presents an important step in validating MRS biomarkers as potential surrogate markers to evaluate therapeutics in pre-clinical and clinical trials in SCA1... - Ginkgo biloba use in nursing home elderly with epilepsy or seizure disorderSusan L Harms
Division of Health Services Research and Policy, School of Public Health, 420 Delaware Street SE, MMC 729, Minneapolis, MN 55455, U S A
Epilepsia 47:323-9. 2006.... - Use of antiepileptic medications in nursing homesJudith Garrard
Division of Health Policy and Management, School of Public Health University of Minnesota, Minneapolis, Minnesota 55455, USA
Int Rev Neurobiol 81:165-82. 2007..Manic depression (bipolar disease) was also significantly associated with initiation of an AED after admission. In this group, there was an inverse relationship between age and initiation of an AED... - Estimated plasma stearoyl co-A desaturase-1 activity and risk of incident diabetes: the Atherosclerosis Risk in Communities (ARIC) studyLisa S Chow
Department of Medicine, University of Minnesota, Minneapolis, MN, USA
Metabolism 62:100-8. 2013..Translation of these findings to humans remains less defined. The purpose of this research was to evaluate the association between different measures of SCD-1 activity and incident diabetes in a large, prospective human study... - Race/ethnicity, income, major risk factors, and cardiovascular disease mortalityAvis J Thomas
Coordinating Centers for Biometric Research, University of Minnesota, 2221 University Ave SE, Suite 200, Minneapolis, MN 55414, USA
Am J Public Health 95:1417-23. 2005..We explored differences between Black and White men for cardiovascular disease (CVD) mortality across major risk factor levels... 
Neurochemical profile of patients with type 1 diabetes measured by (1)H-MRS at 4 TSilvia Mangia
Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, USA
J Cereb Blood Flow Metab 33:754-9. 2013..No other differences in metabolites were observed between subjects with T1DM and controls...- Hypoglycemia-induced increases in thalamic cerebral blood flow are blunted in subjects with type 1 diabetes and hypoglycemia unawarenessSilvia Mangia
Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Cereb Blood Flow Metab 32:2084-90. 2012..A positive correlation was observed between thalamic response and epinephrine response to hypoglycemia, suggesting that this region may be involved in the coordination of the counter regulatory response to hypoglycemia... - Latino risk-adjusted mortality in the men screened for the Multiple Risk Factor Intervention TrialAvis J Thomas
Coordinating Centers for Biometric Research, Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN 55414, USA
Am J Epidemiol 162:569-78. 2005..Results were not likely an artifact of return migration or incomplete mortality data... - The association of physical activity with lung cancer incidence in a cohort of older women: the Iowa Women's Health StudyPenny Sinner
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454-1015, USA
Cancer Epidemiol Biomarkers Prev 15:2359-63. 2006..63 (95% CI, 0.43-0.92) in former smokers, but was not significant in never smokers. CONCLUSION: These results suggest that physical activity might reduce the risk of lung cancer in women who are current or former smokers... - Comparing exposure zones by different exposure metrics using statistical parameters: contrast and precisionJi Young Park
University of Minnesota, Minneapolis, 55455, USA
Ann Occup Hyg 54:799-812. 2010..Because the choice of an exposure metric has significant implications for epidemiologic studies and industrial hygiene practice, a multimetric sampling approach is recommended for nanoparticle exposure assessment... - Prevalence of appropriate and problematic antiepileptic combination therapy in older people in the nursing homeSusan L Harms
Division of Health Services Research and Policy, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Am Geriatr Soc 53:1023-8. 2005.... - Longitudinal evaluation of allergen and culturable fungal concentrations in inner-city householdsSook Ja Cho
Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
J Occup Environ Hyg 5:107-18. 2008..Total culturable fungi will require greater than nine repeated measurements for robust assessment of long-term exposures because of low correlations in fungal measures over time... - Human brain glycogen metabolism during and after hypoglycemiaGULIN OZ
Center for MR Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota, USA
Diabetes 58:1978-85. 2009..We tested the hypotheses that human brain glycogen is mobilized during hypoglycemia and its content increases above normal levels ("supercompensates") after hypoglycemia... - Antiepileptic drug use in nursing home admissionsJudith Garrard
Division of Health Services Research and Policy, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
Ann Neurol 54:75-85. 2003..Results also show that the rate of AED use in nursing homes is not static... - Neurochemical changes in the rat prefrontal cortex following acute phencyclidine treatment: an in vivo localized (1)H MRS studyIsabelle Iltis
Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, 55455, USA
NMR Biomed 22:737-44. 2009..MRS studies of this pharmacological rat model may be useful for assessing the effects of potential anti-psychotic drugs in vivo... - Body size and predatory performance in wolves: is bigger better?Daniel R MacNulty
Department of Ecology, Evolution and Behaviour, University of Minnesota, 1987 Upper Buford Circle, St Paul, MN 55108, USA
J Anim Ecol 78:532-9. 2009..We argue that this could potentially narrow the dietary niche of larger carnivores as well as limit the evolution of larger size if prey are substantially more difficult to pursue than to handle... - Predicting children's short-term exposure to pesticides: results of a questionnaire screening approachKen Sexton
Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
Environ Health Perspect 111:123-8. 2003..Results indicate that the residential pesticide-use questions and overall screening approach used in the MNCPES were ineffective for identifying and oversampling children/households with higher levels of individual target pesticides... - Variations in product choices of frequently purchased herbs: caveat emptorJudith Garrard
Divisions of Health Services Research and Policy, School of Public Health, and College of Pharmacy, University of Minnesota, Minneapolis 55455, USA
Arch Intern Med 163:2290-5. 2003..The purpose of this study was to describe variations in label information of products for each of the 10 most commonly purchased herbs... - Agreement of pesticide biomarkers between morning void and 24-h urine samples from farmers and their childrenDeanna P Scher
Environmental Health Sciences Division, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
J Expo Sci Environ Epidemiol 17:350-7. 2007..g., farm families), the pharmacokinetics of the pesticide and the timing of exposure events and urine collection must be understood when relying on single voids as a surrogate for longer time-frames of exposure... - Personal, indoor, and outdoor VOC exposures in a probability sample of childrenJohn L Adgate
Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis, MN 55455, USA
J Expo Anal Environ Epidemiol 14:S4-S13. 2004..There are relatively little data on VOC exposures in children, so these results are useful for estimating the central tendency and distribution of VOC exposures in locations where children spend a majority of their time... - Brain glycogen content and metabolism in subjects with type 1 diabetes and hypoglycemia unawarenessGULIN OZ
Department of Radiology, Center for Magnetic Resonance Research, Medical School, University of Minnesota, Minneapolis, Minnesota, USA
J Cereb Blood Flow Metab 32:256-63. 2012..Metabolic modeling indicated lower brain glycogen content in patients than in controls (P=0.07), implying that glycogen supercompensation does not contribute to the development of hypoglycemia unawareness in humans with type 1 diabetes... - Multiple linear regressionLynn E Eberly
Division of Biostatistics, University of Minnesota, Minneapolis, MN, USA
Methods Mol Biol 404:165-87. 2007..The special cases of regression with interactions among the variables, polynomial regression, regressions with categorical (grouping) variables, and separate slopes models are also covered. Examples in microbiology are used throughout... - (1)H MR spectroscopy in Friedreich's ataxia and ataxia with oculomotor apraxia type 2Isabelle Iltis
Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN 55455, USA
Brain Res 1358:200-10. 2010..We aimed at assessing the neurochemical profile of the pons, the cerebellar hemisphere and the vermis in patients with FRDA and AOA2 to identify potential biomarkers of these diseases... - Impulsive behavior and associated clinical variables in Parkinson's diseaseAviva Abosch
Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Psychosomatics 52:41-7. 2011..Parkinson's disease (PD) is a degenerative brain disorder accompanied by the loss of dopaminergic neurons and the presence of motor and non-motor symptoms... - Acute free fatty acid elevation eliminates endurance training effect on insulin sensitivityLisa S Chow
Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Clin Endocrinol Metab 97:2890-7. 2012..Both training and normal body mass index are associated with high insulin sensitivity, but the mechanism may be different... - Pulmonary function as a predictor of lung cancer mortality in continuing cigarette smokers and in quittersLynn E Eberly
Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA
Int J Epidemiol 32:592-9. 2003..FEV(1) may be a biological marker for smoking dose or it may be that genetic susceptibilities to both decreased FEV(1) and lung cancer are associated... - Ninety-day mortality after intertrochanteric hip fracture: does provider volume matter?Mary L Forte
University of Minnesota, Minneapolis, Minnesota, USA
J Bone Joint Surg Am 92:799-806. 2010..This study examined the association between surgeon and hospital volumes of procedures performed for the treatment of intertrochanteric hip fractures in Medicare beneficiaries and inpatient through ninety-day postoperative mortality... - Noninvasive detection of presymptomatic and progressive neurodegeneration in a mouse model of spinocerebellar ataxia type 1GULIN OZ
Center for Magnetic Resonance Research, Department of Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Neurosci 30:3831-8. 2010..These data demonstrate that presymptomatic and progressive neurodegeneration in SCA1 can be noninvasively monitored using MRS... - GEE estimation of a misspecified time-varying covariate: an example with the effect of alcoholism treatment on medical utilizationMelanie M Wall
Division of Biostatistics, School of Public Health at the University of Minnesota, Minneapolis, MN 55455, USA
Stat Med 24:925-39. 2005..A simulation study is performed to demonstrate that misspecification of the time-varying covariate in the marginal mean structure can cause differences in GEE results across various choices of working correlation structure... - Correlation and simple linear regressionLynn E Eberly
Division of Biostatistics, University of Minnesota, Minneapolis, MN, USA
Methods Mol Biol 404:143-64. 2007..This chapter provides a framework that is helpful in understanding more complex statistical techniques, such as multiple linear regression, linear mixed effects models, logistic regression, and proportional hazards regression... - Associations of smoking prevalence with individual and area level social cohesionJoan M Patterson
University of Minnesota School of Public Health, Minneapolis, USA
J Epidemiol Community Health 58:692-7. 2004..To discover if area level social cohesion, neighbourhood safety, and home safety are associated with current cigarette smoking among adults after adjustment for concentrations of poverty and low education... - Sex differences in learning in chimpanzeesElizabeth V Lonsdorf
Department of Ecology, Evolution and Behavior, University of Minnesota, Saint Paul, Minnesota 55108, USA
Nature 428:715-6. 2004..We find that there are distinct sex-based differences, akin to those found in human children, in the way in which young chimpanzees develop their termite-fishing skills...