Research Topics
| Scott EarleySummaryAffiliation: University of Vermont Country: USA Publications
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Detail Information
Publications
Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteriesScott Earley
Department of Pharmacology, University of Vermont College of Medicine, 89 Beaumont Ave, Burlington, VT, USA
Circ Res 95:922-9. 2004..We concluded that activation of TRPM4-dependent currents contributed to myogenic vasoconstriction of cerebral arteries...
TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channelsScott Earley
Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT 05405, USA
Circ Res 97:1270-9. 2005....
Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flowJoseph E Brayden
Department of Pharmacology, The University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA
Clin Exp Pharmacol Physiol 35:1116-20. 2008..g. hypertension, stroke, vasospasm)...
TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressureScott Earley
Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT 05405, USA
Am J Physiol Heart Circ Physiol 297:H1096-102. 2009....
Protein kinase C regulates vascular myogenic tone through activation of TRPM4Scott Earley
Department of Biomedical Sciences, Colorado State Univeristy, Fort Collins, CO USA 80523 1680, USA
Am J Physiol Heart Circ Physiol 292:H2613-22. 2007..We conclude that PKC-dependent regulation of TRPM4 activity contributes to the control of cerebral artery myogenic tone...
Central role of Ca2+-dependent regulation of vascular tone in vivoScott Earley
J Appl Physiol 101:10-1. 2006
Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstrictionJay S Naik
Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
J Appl Physiol 98:1119-24. 2005..We conclude that the pulmonary circulation of the rat does not demonstrate pressure-induced vasoconstriction...
Disruption of smooth muscle gap junctions attenuates myogenic vasoconstriction of mesenteric resistance arteriesScott Earley
Dept of Cell Biology and Physiology, MSC08 4750, 1 Univ of New Mexico, Albuquerque, NM 87131 0001, USA
Am J Physiol Heart Circ Physiol 287:H2677-86. 2004..4 +/- 1.5 mV) and Gap20-treated (-38.4 +/- 0.7 mV) vessels. Our findings suggest that inhibition of smooth muscle gap junctions attenuates pressure-induced VSM cell depolarization and myogenic vasoconstriction...
Increased nitric oxide production following chronic hypoxia contributes to attenuated systemic vasoconstrictionScott Earley
Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
Am J Physiol Heart Circ Physiol 284:H1655-61. 2003..We conclude that enhanced production of NO resulting from elevated endothelial cell [Ca(2+)] contributes to attenuated reactivity following CH by decreasing VSM cell Ca(2+) sensitivity...
Endothelium-dependent blunting of myogenic responsiveness after chronic hypoxiaScott Earley
Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque 87131 5218, USA
Am J Physiol Heart Circ Physiol 283:H2202-9. 2002..We conclude that blunted myogenic reactivity after chronic hypoxia results from a non-NO, endothelium-dependent VSM cell hyperpolarizing influence...
Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxiaScott Earley
Department of Cell Biology and Physiology, University of New Mexico, Albuquerque, NM 87131 0001, USA
Am J Physiol Heart Circ Physiol 285:H127-36. 2003..We conclude that enhanced CYP2C9 expression and 11,12-EET production following CH contributes to BKCa channel-dependent VSM cell hyperpolarization and attenuated vasoreactivity...
