Scott Earley

Summary

Affiliation: University of Vermont
Country: USA

Publications

  1. ncbi TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels
    Scott Earley
    Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Circ Res 97:1270-9. 2005
  2. ncbi Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries
    Scott Earley
    Department of Pharmacology, University of Vermont College of Medicine, 89 Beaumont Ave, Burlington, VT, USA
    Circ Res 95:922-9. 2004
  3. doi Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow
    Joseph E Brayden
    Department of Pharmacology, The University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA
    Clin Exp Pharmacol Physiol 35:1116-20. 2008
  4. ncbi A PLCĪ³1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries
    Albert L Gonzales
    Vascular Physiology Research Group, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA Department of Pharmacology, University of Vermont, Burlington, VT 05405, USA
    Sci Signal 7:ra49. 2014
  5. pmc TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure
    Scott Earley
    Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Am J Physiol Heart Circ Physiol 297:H1096-102. 2009
  6. ncbi Disruption of smooth muscle gap junctions attenuates myogenic vasoconstriction of mesenteric resistance arteries
    Scott Earley
    Dept of Cell Biology and Physiology, MSC08 4750, 1 Univ of New Mexico, Albuquerque, NM 87131 0001, USA
    Am J Physiol Heart Circ Physiol 287:H2677-86. 2004
  7. ncbi Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction
    Jay S Naik
    Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    J Appl Physiol 98:1119-24. 2005
  8. ncbi Central role of Ca2+-dependent regulation of vascular tone in vivo
    Scott Earley
    J Appl Physiol 101:10-1. 2006
  9. ncbi Protein kinase C regulates vascular myogenic tone through activation of TRPM4
    Scott Earley
    Department of Biomedical Sciences, Colorado State Univeristy, Fort Collins, CO USA 80523 1680, USA
    Am J Physiol Heart Circ Physiol 292:H2613-22. 2007
  10. ncbi Increased nitric oxide production following chronic hypoxia contributes to attenuated systemic vasoconstriction
    Scott Earley
    Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    Am J Physiol Heart Circ Physiol 284:H1655-61. 2003

Collaborators

Detail Information

Publications12

  1. ncbi TRPV4 forms a novel Ca2+ signaling complex with ryanodine receptors and BKCa channels
    Scott Earley
    Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Circ Res 97:1270-9. 2005
    ....
  2. ncbi Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries
    Scott Earley
    Department of Pharmacology, University of Vermont College of Medicine, 89 Beaumont Ave, Burlington, VT, USA
    Circ Res 95:922-9. 2004
    ..We concluded that activation of TRPM4-dependent currents contributed to myogenic vasoconstriction of cerebral arteries...
  3. doi Transient receptor potential (TRP) channels, vascular tone and autoregulation of cerebral blood flow
    Joseph E Brayden
    Department of Pharmacology, The University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA
    Clin Exp Pharmacol Physiol 35:1116-20. 2008
    ..g. hypertension, stroke, vasospasm)...
  4. ncbi A PLCĪ³1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries
    Albert L Gonzales
    Vascular Physiology Research Group, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA Department of Pharmacology, University of Vermont, Burlington, VT 05405, USA
    Sci Signal 7:ra49. 2014
    ....
  5. pmc TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure
    Scott Earley
    Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Am J Physiol Heart Circ Physiol 297:H1096-102. 2009
    ....
  6. ncbi Disruption of smooth muscle gap junctions attenuates myogenic vasoconstriction of mesenteric resistance arteries
    Scott Earley
    Dept of Cell Biology and Physiology, MSC08 4750, 1 Univ of New Mexico, Albuquerque, NM 87131 0001, USA
    Am J Physiol Heart Circ Physiol 287:H2677-86. 2004
    ..4 +/- 1.5 mV) and Gap20-treated (-38.4 +/- 0.7 mV) vessels. Our findings suggest that inhibition of smooth muscle gap junctions attenuates pressure-induced VSM cell depolarization and myogenic vasoconstriction...
  7. ncbi Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction
    Jay S Naik
    Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    J Appl Physiol 98:1119-24. 2005
    ..We conclude that the pulmonary circulation of the rat does not demonstrate pressure-induced vasoconstriction...
  8. ncbi Central role of Ca2+-dependent regulation of vascular tone in vivo
    Scott Earley
    J Appl Physiol 101:10-1. 2006
  9. ncbi Protein kinase C regulates vascular myogenic tone through activation of TRPM4
    Scott Earley
    Department of Biomedical Sciences, Colorado State Univeristy, Fort Collins, CO USA 80523 1680, USA
    Am J Physiol Heart Circ Physiol 292:H2613-22. 2007
    ..We conclude that PKC-dependent regulation of TRPM4 activity contributes to the control of cerebral artery myogenic tone...
  10. ncbi Increased nitric oxide production following chronic hypoxia contributes to attenuated systemic vasoconstriction
    Scott Earley
    Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
    Am J Physiol Heart Circ Physiol 284:H1655-61. 2003
    ..We conclude that enhanced production of NO resulting from elevated endothelial cell [Ca(2+)] contributes to attenuated reactivity following CH by decreasing VSM cell Ca(2+) sensitivity...
  11. ncbi Endothelium-dependent blunting of myogenic responsiveness after chronic hypoxia
    Scott Earley
    Vascular Physiology Group, Department of Cell Biology and Physiology, University of New Mexico Health Sciences Center, Albuquerque 87131 5218, USA
    Am J Physiol Heart Circ Physiol 283:H2202-9. 2002
    ..We conclude that blunted myogenic reactivity after chronic hypoxia results from a non-NO, endothelium-dependent VSM cell hyperpolarizing influence...
  12. ncbi Cytochrome p-450 epoxygenase products contribute to attenuated vasoconstriction after chronic hypoxia
    Scott Earley
    Department of Cell Biology and Physiology, University of New Mexico, Albuquerque, NM 87131 0001, USA
    Am J Physiol Heart Circ Physiol 285:H127-36. 2003
    ..We conclude that enhanced CYP2C9 expression and 11,12-EET production following CH contributes to BKCa channel-dependent VSM cell hyperpolarization and attenuated vasoreactivity...