Nathaniel A Dyment
Affiliation: University of Cincinnati
- The relationships among spatiotemporal collagen gene expression, histology, and biomechanics following full-length injury in the murine patellar tendonNathaniel A Dyment
University of Cincinnati, Cincinnati, OH, USA
J Orthop Res 30:28-36. 2012..Future studies will further characterize the cells within the healing midsubstance and insertion using tenogenic markers and compare these results to those of tendon cells during normal development...
- Improved biomechanical and biological outcomes in the MRL/MpJ murine strain following a full-length patellar tendon injuryAndrea L Lalley
Biomedical Engineering Program, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio
J Orthop Res 33:1693-703. 2015..2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1693-1703, 2015...
- Ablating hedgehog signaling in tenocytes during development impairs biomechanics and matrix organization of the adult murine patellar tendon enthesisAndrew P Breidenbach
Department of Biomedical, Biomedical Engineering Program, Chemical and Environmental Engineering, University of Cincinnati, Cincinnati, Ohio
J Orthop Res 33:1142-51. 2015..These results indicate that Ihh signaling plays a critical role in the mineralization process of fibrocartilaginous entheses and may be a novel therapeutic to promote tendon-to-bone healing...
- The use of mesenchymal stem cells in collagen-based scaffolds for tissue-engineered repair of tendonsDavid L Butler
Department of Biomedical Engineering, Colleges of Engineering and Medicine, University of Cincinnati, Cincinnati, Ohio, USA
Nat Protoc 5:849-63. 2010..The in vivo portion, from TEC implantation to limb harvest, takes 84 d. One complete loop around the tissue engineering road map, as presented here, takes 138 d to complete...
- Fibrin gels exhibit improved biological, structural, and mechanical properties compared with collagen gels in cell-based tendon tissue-engineered constructsAndrew P Breidenbach
1 Biomedical Engineering Program, Department of Biomedical, Chemical and Environmental Engineering, College of Engineering and Applied Science, University of Cincinnati, Cincinnati, Ohio
Tissue Eng Part A 21:438-50. 2015....
- Functional tissue engineering of tendon: Establishing biological success criteria for improving tendon repairAndrew P Breidenbach
Biomedical Engineering Program, College of Engineering and Applied Science, 601 Engineering Research Center, ML 0048, University of Cincinnati, Cincinnati, OH 45221 0048, United States Electronic address
J Biomech 47:1941-8. 2014..Moving forward, these biological success criteria will be used in conjunction with our already established mechanical success criteria to evaluate the effectiveness of our tissue-engineered tendon repairs. ..