Genomes and Genes
Noelle D Dwyer
Affiliation: University of Virginia
- A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotypeNoelle D Dwyer
Howard Hughes Medical Institute, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA
Neural Dev 6:3. 2011..The axons grow along a complex multistep pathway, making sharp turns, crossing expression boundaries, and encountering intermediate targets. However, the cellular and molecular components mediating these steps remain poorly understood...
- Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210Patrick Smits
Orthopedic Research Laboratories, Department of Orthopedic Surgery, Children s Hospital, Boston, MA 02115, USA
N Engl J Med 362:206-16. 2010..Establishing the genetic basis of phenotypes such as skeletal dysplasia in model organisms can provide insights into biologic processes and their role in human disease...
- Utilization of a whole genome SNP panel for efficient genetic mapping in the mouseJennifer L Moran
Genetics Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Genome Res 16:436-40. 2006..By using this approach, we identified DNA sequence changes in two ethylnitrosourea-induced mutants...
- Molecular Mechanisms of Thalamocortical DevelopmentNOELLE DWYER; Fiscal Year: 2007..Combining the expertise in mouse genetics with the previous training in mouse neuroanatomy and nematode genetics will significantly add to the Candidate's potential to make a strong impact on the field. ..