Robert C Dutton

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Forty-hertz midlatency auditory evoked potential activity predicts wakeful response during desflurane and propofol anesthesia in volunteers
    R C Dutton
    Department of Anesthesia and Perioperative Care, University of California San Francisco, 94143 0464, USA
    Anesthesiology 91:1209-20. 1999
  2. ncbi request reprint The concentration of isoflurane required to suppress learning depends on the type of learning
    R C Dutton
    Department of Anesthesia and Perioperative Care, University of California San Francisco, 94143 0464, USA
    Anesthesiology 94:514-9. 2001
  3. ncbi request reprint Short-term memory resists the depressant effect of the nonimmobilizer 1-2-dichlorohexafluorocyclobutane (2N) more than long-term memory
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California, San Francisco 94143 0464, USA
    Anesth Analg 94:631-9; table of contents. 2002
  4. ncbi request reprint Isoflurane causes anterograde but not retrograde amnesia for pavlovian fear conditioning
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94143 0464, USA
    Anesthesiology 96:1223-9. 2002
  5. ncbi request reprint Temporal summation governs part of the minimum alveolar concentration of isoflurane anesthesia
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, California 94143 0464, USA
    Anesthesiology 98:1372-7. 2003
  6. ncbi request reprint The excitatory and inhibitory effects of nitrous oxide on spinal neuronal responses to noxious stimulation
    Joseph F Antognini
    Department of Anesthesiology and Pain Medicine, University of California, Davis, California 95616, USA
    Anesth Analg 104:829-35. 2007
  7. ncbi request reprint Do N-methyl-D-aspartate receptors mediate the capacity of inhaled anesthetics to suppress the temporal summation that contributes to minimum alveolar concentration?
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, California 94143 0464, USA
    Anesth Analg 102:1412-8. 2006
  8. ncbi request reprint Administration of epinephrine does not increase learning of fear to tone in rats anesthetized with isoflurane or desflurane
    James M Sonner
    Department of Anesthesia and Perioperative Care S 455, University of California San Francisco, San Francisco, CA 94143 0464, USA
    Anesth Analg 100:1333-7, table of contents. 2005
  9. ncbi request reprint Contrasting roles of the N-methyl-D-aspartate receptor in the production of immobilization by conventional and aromatic anesthetics
    Edmond I Eger
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143 0464, USA
    Anesth Analg 102:1397-406. 2006
  10. pmc A method for recording single unit activity in lumbar spinal cord in rats anesthetized with nitrous oxide in a hyperbaric chamber
    Joseph F Antognini
    Department of Anesthesiology and Pain Medicine, University of California, Davis, TB 170, Davis, CA 95616, USA
    J Neurosci Methods 160:215-22. 2007

Detail Information

Publications15

  1. ncbi request reprint Forty-hertz midlatency auditory evoked potential activity predicts wakeful response during desflurane and propofol anesthesia in volunteers
    R C Dutton
    Department of Anesthesia and Perioperative Care, University of California San Francisco, 94143 0464, USA
    Anesthesiology 91:1209-20. 1999
    ..The authors sought midlatency auditory evoked potential indices that successfully differentiated wakeful responsiveness and unconsciousness...
  2. ncbi request reprint The concentration of isoflurane required to suppress learning depends on the type of learning
    R C Dutton
    Department of Anesthesia and Perioperative Care, University of California San Francisco, 94143 0464, USA
    Anesthesiology 94:514-9. 2001
    ..To determine whether these types of learning were differentially affected by anesthesia, the authors applied isoflurane during the training phases of fear conditioning paradigms for freezing to context and freezing to tone...
  3. ncbi request reprint Short-term memory resists the depressant effect of the nonimmobilizer 1-2-dichlorohexafluorocyclobutane (2N) more than long-term memory
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California, San Francisco 94143 0464, USA
    Anesth Analg 94:631-9; table of contents. 2002
    ..5% 2N does not preclude transmission of tone and shock signals to the site where tone-shock associations are formed...
  4. ncbi request reprint Isoflurane causes anterograde but not retrograde amnesia for pavlovian fear conditioning
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94143 0464, USA
    Anesthesiology 96:1223-9. 2002
    ..Such disruption would allow suppression of memory of previous untoward events. The authors examined whether isoflurane provides retrograde amnesia for classic (Pavlovian) fear conditioning...
  5. ncbi request reprint Temporal summation governs part of the minimum alveolar concentration of isoflurane anesthesia
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, California 94143 0464, USA
    Anesthesiology 98:1372-7. 2003
    ..General anesthesia may delay the onset of movement in response to noxious stimulation. The authors hypothesized that the production of immobility could involve depression of time-related processes involved in the generation of movement...
  6. ncbi request reprint The excitatory and inhibitory effects of nitrous oxide on spinal neuronal responses to noxious stimulation
    Joseph F Antognini
    Department of Anesthesiology and Pain Medicine, University of California, Davis, California 95616, USA
    Anesth Analg 104:829-35. 2007
    ..We hypothesized that, like other inhaled anesthetics, N2O would depress spinal neuronal responses to noxious stimulation...
  7. ncbi request reprint Do N-methyl-D-aspartate receptors mediate the capacity of inhaled anesthetics to suppress the temporal summation that contributes to minimum alveolar concentration?
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, California 94143 0464, USA
    Anesth Analg 102:1412-8. 2006
    ..NMDA receptor blockade may contribute to the MAC produced by inhaled anesthetics that potently inhibit NMDA receptors in vitro but not those that have a limited in vitro effect...
  8. ncbi request reprint Administration of epinephrine does not increase learning of fear to tone in rats anesthetized with isoflurane or desflurane
    James M Sonner
    Department of Anesthesia and Perioperative Care S 455, University of California San Francisco, San Francisco, CA 94143 0464, USA
    Anesth Analg 100:1333-7, table of contents. 2005
    ..36 +/- 0.04 MAC in rats injected with 0.1 mg/kg of epinephrine i.p. We conclude that exogenous epinephrine does not decrease amnesia produced by inhaled isoflurane or desflurane, as assessed by fear conditioning to a tone in rats...
  9. ncbi request reprint Contrasting roles of the N-methyl-D-aspartate receptor in the production of immobilization by conventional and aromatic anesthetics
    Edmond I Eger
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143 0464, USA
    Anesth Analg 102:1397-406. 2006
    ..We conclude that some aromatic anesthetics may produce immobility in the face of noxious stimulation by blocking the action of glutamate on NMDA receptors but that conventional inhaled anesthetics do not...
  10. pmc A method for recording single unit activity in lumbar spinal cord in rats anesthetized with nitrous oxide in a hyperbaric chamber
    Joseph F Antognini
    Department of Anesthesiology and Pain Medicine, University of California, Davis, TB 170, Davis, CA 95616, USA
    J Neurosci Methods 160:215-22. 2007
    ..This technique is well-suited to study actions of weak anesthetics such as N(2)O and Xe at working pressures of 4-5 atm or greater. The safety of such pressures depends on the wall thickness and chamber diameter...
  11. ncbi request reprint Temporal and spatial determinants of sacral dorsal horn neuronal windup in relation to isoflurane-induced immobility
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, California, USA
    Anesth Analg 105:1665-74, table of contents. 2007
    ....
  12. ncbi request reprint Long ascending propriospinal projections from lumbosacral to upper cervical spinal cord in the rat
    Robert C Dutton
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143, USA
    Brain Res 1119:76-85. 2006
    ..These propriospinal projections may be involved in coordinating head and neck movements during locomotion or stimulus-evoked motor responses...
  13. ncbi request reprint Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration
    James M Sonner
    Department of Anesthesia and Perioperative Care, University of California, San Francisco, California, USA
    Anesth Analg 97:718-40. 2003
    ..g., gamma-aminobutyric acid A, acetylcholine, potassium, 5-hydroxytryptamine-3, opioids, and alpha(2)-adrenergic), whereas other receptors/channels (e.g., glycine, N-methyl-D-aspartate, and sodium) remain credible candidates...
  14. ncbi request reprint Isoflurane depresses windup of C fiber-evoked limb withdrawal with variable effects on nociceptive lumbar spinal neurons in rats
    Steven L Jinks
    Department of Anesthesiology and Pain Medicine, University of California Davis, One Shields Drive, Davis, CA 95616, USA
    Anesth Analg 99:1413-9; table of contents. 2004
    ..7 MAC value at 0.9, 1.1, and 1.4 MAC, respectively. Isoflurane depressed excitability and variably affected windup of lumbar spinal cord neurons, while uniformly depressing windup of limb withdrawals in a concentration-dependent manner...
  15. ncbi request reprint The differential effects of halothane and isoflurane on windup of dorsal horn neurons selected in unanesthetized decerebrated rats
    Toshihiko Mitsuyo
    Department of Anesthesiology and Resuscitology, Ehime University Medical School, Matsuyama, Japan
    Anesth Analg 103:753-60. 2006
    ..2 MAC halothane, but not isoflurane, suggests different sites of immobilizing action for these two anesthetics. Immobility seems to not be mediated by severe anesthetic depression of a subpopulation of nociceptive neurons...