T Durduran

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation
    Turgut Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 29:1766-8. 2004
  2. ncbi request reprint Bulk optical properties of healthy female breast tissue
    T Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA
    Phys Med Biol 47:2847-61. 2002
  3. ncbi request reprint Diffuse optical measurement of blood flow in breast tumors
    Turgut Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 30:2915-7. 2005
  4. ncbi request reprint Spatiotemporal quantification of cerebral blood flow during functional activation in rat somatosensory cortex using laser-speckle flowmetry
    Turgut Durduran
    Departments of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cereb Blood Flow Metab 24:518-25. 2004
  5. ncbi request reprint Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging
    J P Culver
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6396, USA
    Med Phys 30:235-47. 2003
  6. ncbi request reprint Near-field diffraction tomography with diffuse photon density waves
    X Li
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 61:4295-309. 2000
  7. pmc Transabdominal near infrared oximetry of hypoxic stress in fetal sheep brain in utero
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 100:12950-4. 2003
  8. ncbi request reprint Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy
    Chao Zhou
    University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania 19104, USA
    J Biomed Opt 12:051903. 2007
  9. ncbi request reprint Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study
    Ulas Sunar
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6396, USA
    J Biomed Opt 11:064021. 2006
  10. ncbi request reprint Real-time in situ monitoring of human prostate photodynamic therapy with diffuse light
    Guoqiang Yu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, USA
    Photochem Photobiol 82:1279-84. 2006

Detail Information

Publications19

  1. ncbi request reprint Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation
    Turgut Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 29:1766-8. 2004
    ..The feasibility for noninvasive optical measurement of blood flow through the skull of an adult brain is thus demonstrated, and the clinical potential of this hybrid, all-optical noninvasive, methodology can now be explored...
  2. ncbi request reprint Bulk optical properties of healthy female breast tissue
    T Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia 19104, USA
    Phys Med Biol 47:2847-61. 2002
    ..The new information on healthy breast tissue provides insight about the potential contrasts available for diffuse optical tomography of breast tumours...
  3. ncbi request reprint Diffuse optical measurement of blood flow in breast tumors
    Turgut Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 30:2915-7. 2005
    ..Increased blood flow was observed in tumor regions relative to healthy tissue, and control subjects did not exhibit significant blood flow heterogeneity. The measurements introduce a new optical contrast for diffuse optical mammography...
  4. ncbi request reprint Spatiotemporal quantification of cerebral blood flow during functional activation in rat somatosensory cortex using laser-speckle flowmetry
    Turgut Durduran
    Departments of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cereb Blood Flow Metab 24:518-25. 2004
    ....
  5. ncbi request reprint Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging
    J P Culver
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6396, USA
    Med Phys 30:235-47. 2003
    ..In addition, we find that point spread function measurements provide a useful and comprehensive representation of system performance...
  6. ncbi request reprint Near-field diffraction tomography with diffuse photon density waves
    X Li
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics 61:4295-309. 2000
    ..g., the slab medium). Limitations and potential improvements of the near-field diffraction tomography are also discussed...
  7. pmc Transabdominal near infrared oximetry of hypoxic stress in fetal sheep brain in utero
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 100:12950-4. 2003
    ..Fetal hypoxia was detected. Good agreement was found between fetal blood saturation determined by the transabdominal NIR method and arterial and venous fetal blood saturation quantified from fetal blood samples by using a hemoximeter...
  8. ncbi request reprint Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy
    Chao Zhou
    University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania 19104, USA
    J Biomed Opt 12:051903. 2007
    ..The hybrid approach also enables construction of indices reflecting tissue metabolic rate of oxygen, which may provide new insights about therapy mechanisms...
  9. ncbi request reprint Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study
    Ulas Sunar
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6396, USA
    J Biomed Opt 11:064021. 2006
    ..0+/-8.1) [microM] at the end of the fourth week of therapy. These preliminary results suggest daily diffuse-optics-based therapy monitoring is feasible during the first two weeks and may have clinical promise...
  10. ncbi request reprint Real-time in situ monitoring of human prostate photodynamic therapy with diffuse light
    Guoqiang Yu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, USA
    Photochem Photobiol 82:1279-84. 2006
    ....
  11. ncbi request reprint Diffuse optical measurement of hemoglobin and cerebral blood flow in rat brain during hypercapnia, hypoxia and cardiac arrest
    Joseph P Culver
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Adv Exp Med Biol 510:293-7. 2003
    ..The new instrument and concept may also be applicable to human studies especially in infants and neonates permitting noninvasive monitoring of cerebral hemodynamics and oxygen (see [4] and [2] for examples of NIR spectroscopy)...
  12. ncbi request reprint Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies
    Guoqiang Yu
    University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania 19104, USA
    J Biomed Opt 10:024027. 2005
    ..The instrument thus provides a method for evaluation of microcirculation and muscle metabolism in patients with vascular diseases...
  13. ncbi request reprint Diffuse optical tomography of breast cancer during neoadjuvant chemotherapy: a case study with comparison to MRI
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, Pennsylvania 19104 6396, USA
    Med Phys 32:1128-39. 2005
    ..A decrease in total hemoglobin concentration contrast between tumor and normal tissue was also observed over time. The results demonstrate the potential of DOT for measuring physiological parameters of breast lesions during chemotherapy...
  14. ncbi request reprint Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic efficacy
    Guoqiang Yu
    Department of Physics and Astronomy, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Clin Cancer Res 11:3543-52. 2005
    ..To monitor tumor blood flow noninvasively during photodynamic therapy (PDT) and to correlate flow responses with therapeutic efficacy...
  15. ncbi request reprint Diffuse optical tomography with spectral constraints and wavelength optimization
    Alper Corlu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Appl Opt 44:2082-93. 2005
    ..Here the technique is described and tested in detail, and optimum wavelength sets for a broad range of chromophore combinations are discovered and analyzed...
  16. ncbi request reprint Frequency-domain multiplexing system for in vivo diffuse light measurements of rapid cerebral hemodynamics
    Guoqiang Yu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Appl Opt 42:2931-9. 2003
    ..We evaluate the performance of the instrument with tissue phantoms, and then employ the system to measure in vivo cerebral blood oxygenation during forepaw stimulation of a rat's brain...
  17. ncbi request reprint Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia
    Joseph P Culver
    Department of Physics and Astronomy, Cerebrovascular Research Center, University of Pennsylvania, Philadelphia, Pennsylvania, U S A
    J Cereb Blood Flow Metab 23:911-24. 2003
    ....
  18. ncbi request reprint Uniqueness and wavelength optimization in continuous-wave multispectral diffuse optical tomography
    Alper Corlu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 28:2339-41. 2003
    ..Application of these concepts should significantly improve the fidelity of continuous-wave diffuse near-infrared optical tomography in tissues...
  19. pmc Acute functional recovery of cerebral blood flow after forebrain ischemia in rat
    Chao Zhou
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Cereb Blood Flow Metab 28:1275-84. 2008
    ..4+/-0.2 secs before ischemia to 3.6+/-0.1 secs at 20 mins into reperfusion (P<0.001); the delay was reduced gradually to 2.9+/-0.2 secs after 3 h, which was still significantly greater than that observed before the insult (P=0.04)...