Research Topics
| D A DuprezSummaryAffiliation: University of Minnesota Country: USA Publications
Research Grants
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Publications
Associations among lung function, arterial elasticity, and circulating endothelial and inflammation markers: the multiethnic study of atherosclerosisDaniel A Duprez
Cardiovascular Division, University of Minnesota, 420 Delaware St SE, MMC 508, Minneapolis, MN
Hypertension 61:542-8. 2013....
Treatment of isolated systolic hypertension in the elderlyDaniel Duprez
Cardiovascular Division, University of Minnesota, 420 Delaware St SE, MMC 508, Minneapolis, MN 55455, USA
Expert Rev Cardiovasc Ther 10:1367-73. 2012..Major effort is required to reduce the therapeutic inertia and increase therapeutic adherence for better blood pressure control in the elderly with systolic hypertension...
Inflammation, coagulation and cardiovascular disease in HIV-infected individualsDaniel A Duprez
University of Minnesota, Minneapolis, Minnesota, United States of America
PLoS ONE 7:e44454. 2012..We studied the predictive value of high sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6) and D-dimer with CVD morbidity and mortality in HIV-infected patients who were enrolled in SMART beyond other measured CVD risk factors...
Arterial stiffness/elasticity in the contribution to progression of heart failureDaniel A Duprez
Cardiovascular Division, University of Minnesota, Minneapolis, 420 Delaware Street South East, MMC 508, Minneapolis, MN 55455, USA
Heart Fail Clin 8:135-41. 2012..The beneficial effect of some cardiovascular therapy on arterial stiffness/elasticity has potential to prevent or delay the progression of heart failure...
Developing pharmaceutical treatments for peripheral artery diseaseDaniel A Duprez
Cardiovascular Division, Mayo Mail Code 508, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA
Expert Opin Investig Drugs 12:101-8. 2003....
Race/ethnic and sex differences in large and small artery elasticity--results of the multi-ethnic study of atherosclerosis (MESA)Daniel A Duprez
Cardiovascular Division, Medical School University of Minnesota, Minneapolis, MN 55455, USA
Ethn Dis 19:243-50. 2009..Reduction in arterial elasticity marks progression toward cardiovascular morbidity and mortality. Variability in arterial elasticity may help account for race/ethnic and gender differences in cardiovascular risk...
Pharmacological interventions for peripheral artery diseaseDaniel A Duprez
University of Minnesota, Cardiovascular Division, Medical School, VCRC Room 270, Minneapolis, MN 55455, USA
Expert Opin Pharmacother 8:1465-77. 2007..New developments should focus on improvement of endothelial function, vascular repair and enhancement of collateral circulation...
Systolic hypertension in the elderly: addressing an unmet needDaniel A Duprez
Cardiovascular Division, Medical School, University of Minnesota, MN 55455, USA
Am J Med 121:179-184.e3. 2008..Therefore, emphasis should be placed on the treatment of systolic hypertension in the elderly, and there is need for more effective, individualized antihypertensive therapy...
Beneficial effects of valsartan in asymptomatic individuals with vascular or cardiac abnormalities: the DETECTIV Pilot StudyDaniel A Duprez
Rasmussen Center for Cardiovascular Disease Prevention, Cardiovascular Division, VCRC Room 270, Mayo Mail Code 508, University of Minnesota Medical School, 420 Delaware Street Southeast, Minneapolis, Minnesota 55455, USA
J Am Coll Cardiol 50:835-9. 2007....
Arterial stiffness as a risk factor for coronary atherosclerosisDaniel A Duprez
Cardiovascular Division, VCRC Room 270, University of Minnesota, 420 Delaware Street SE, MMC 508, Minneapolis, MN 55455, USA
Curr Atheroscler Rep 9:139-44. 2007..Promising study results show that measurement of arterial stiffness could become an important part of the routine assessment of patients in daily practice...
Does it matter how you lower blood pressure in patients with uncomplicated hypertension? Weighing the evidenceDaniel A Duprez
Cardiovascular Division, VCRC Room 270, University of Minnesota, 420 Delaware Street SE, MMC 508, Minneapolis, MN 55455, USA
Curr Atheroscler Rep 9:352-8. 2007..Maintaining vascular health within the scope of global risk reduction in a personalized manner will be the cornerstone of modern cardiovascular disease prevention rather than waiting until arterial hypertension develops...
Identifying early cardiovascular disease to target candidates for treatmentDaniel A Duprez
Cardiovascular Division, Rasmussen Center for Cardiovascular Disease Prevention, University of Minnesota Medical School, 420 Delaware Street SE, Minneapolis, MN 55455, USA
J Clin Hypertens (Greenwich) 10:226-31. 2008..Each test is individually scored, and the total disease score is the sum of all the test scores. A study is ongoing to compare the new disease score vs the classical Framingham risk estimate in the prediction of cardiovascular events...
Aldosterone and the vasculature: mechanisms mediating resistant hypertensionDaniel A Duprez
Cardiovascular Division, University of Minnesota, Minneapolis, MN 55455, USA
J Clin Hypertens (Greenwich) 9:13-8. 2007..Understanding the vascular mechanisms of aldosterone in resistant hypertension may explain why selective aldosterone receptor blockers might have beneficial effects in resistant hypertension...
Is vascular stiffness a target for therapy?Daniel A Duprez
Cardiovascular Division, Medical School, University of Minnesota, VCRC Room 270, 420 Delaware St SE, MMC 508, Minneapolis, MN 55455, USA
Cardiovasc Drugs Ther 24:305-10. 2010..Moreover arterial elasticity provides extra prognostic information beyond arterial blood pressure measurement. Arterial stiffness attenuation may reflect the true reduction of arterial wall damage...
Aliskiren for geriatric lowering of systolic hypertension: a randomized controlled trialD A Duprez
Cardiovascular Division, Medical School, University of Minnesota, Minneapolis, MN 55544, USA
J Hum Hypertens 24:600-8. 2010..001). In elderly patients with systolic hypertension, aliskiren proved to be more effective and better overall anti-hypertensive therapy compared to ramipril...
Determinants of radial artery pulse wave analysis in asymptomatic individualsDaniel A Duprez
Cardiovascular Division, University of Minnesota, Minneapolis, Minnesota 55455, USA
Am J Hypertens 17:647-53. 2004....
Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZDaniel Duprez
Cardiovascular Division, Universityof Minnesota, 420 Delaware St SE, MMC 508, Minneapolis, MN 55455, USA
Vasc Health Risk Manag 7:701-8. 2011..Stage 2 hypertension often requires combination antihypertensive therapy. Ambulatory blood pressure monitoring (ABPM) is a useful tool for assessing antihypertensive drugs and their combinations...
Relationship between C-reactive protein and arterial stiffness in an asymptomatic populationD A Duprez
Department of Medicine, Rasmussen Center for Cardiovascular Disease Prevention, Cardiovascular Division, University of Minnesota Medical School, Minneapolis, 55455, USA
J Hum Hypertens 19:515-9. 2005....
Effect of valsartan, hydrochlorothiazide, and their combination on 24-h ambulatory blood pressure response in elderly patients with systolic hypertension: a ValVET substudyDaniel A Duprez
University of Minnesota, Minneapolis, USA
Blood Press Monit 16:186-96. 2011..Stage 2 hypertension often requires combination antihypertensive therapy. Ambulatory blood pressure monitoring (ABPM) is a useful tool for studying antihypertensive drugs and their combinations...
Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical reviewDaniel A Duprez
Cardiovascular Division, Medical School, University of Minnesota, Minneapolis 55455, USA
J Hypertens 24:983-91. 2006..Understanding the molecular and cellular mechanisms that participate in the early development of hypertensive vascular disease may lead to more targeted treatment and improved outcomes...
Association of small artery elasticity with incident cardiovascular disease in older adults: the multi-ethnic study of atherosclerosisDaniel A Duprez
Cardiovascular Division, Medical School, University of Minnesota, VCRC Room 270, MMC 508, 420 Delaware Street SE, Minneapolis, MN 55455, USA
Am J Epidemiol 174:528-36. 2011..After adjustment, LAE was not significantly related to CVD. In asymptomatic participants free of overt CVD, lower SAE added prognostic information for CVD, CHD, stroke, and heart failure events...
N-terminal-proB-type natriuretic peptide predicts cardiovascular disease events in HIV-infected patientsDaniel A Duprez
Cardiovascular Division, University of Minnesota, Minneapolis, 55455, USA
AIDS 25:651-7. 2011..We aimed to quantify the risk of CVD events associated with NT-proBNP at baseline in the Strategies for Management of Anti-Retroviral Therapy study...
Lipoprotein particle subclasses, cardiovascular disease and HIV infectionDaniel A Duprez
Cardiovascular Division, University of Minnesota, Minneapolis, MN 55455, USA
Atherosclerosis 207:524-9. 2009..SMART was a trial of intermittent use of ART (drug conservation [DC]) versus continuous of ART (viral suppression [VS])...
Serum phosphorus concentrations and arterial stiffness among individuals with normal kidney function to moderate kidney disease in MESAJoachim H Ix
Department of Medicine, Division of Nephrology and Hypertension, University of California San Diego, San Diego, CA 92161, USA
Clin J Am Soc Nephrol 4:609-15. 2009..Higher phosphorus levels are associated with cardiovascular disease (CVD) events and mortality. Whether vascular stiffness may be responsible is unknown...
Monitoring vascular health beyond blood pressureDaniel A Duprez
Rasmussen Center for Cardiovascular Disease Prevention, Medical School, University of Minnesota, 420 Delaware Street SE, Minneapolis, 55455, USA
Curr Hypertens Rep 8:287-91. 2006....
Time to foster a rational approach to preventing cardiovascular morbid eventsJay N Cohn
Rasmussen Center for Cardiovascular Disease Prevention, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA
J Am Coll Cardiol 52:327-9. 2008..More extensive data to confirm the sensitivity and specificity of this scoring system and to demonstrate its utility in tracking the response to therapy are needed to justify widespread application in clinical practice...
Arterial elasticity as part of a comprehensive assessment of cardiovascular risk and drug treatmentJay N Cohn
Cardiovascular Division, Department of Medicine, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA
Hypertension 46:217-20. 2005....
N-terminal pro B-type natriuretic peptide predicts mortality in patients with left ventricular hypertrophySantiago Garcia
Department of Medicine, Cardiology Section, University of Minnesota, Minneapolis, Minnesota, United States
Int J Cardiol 143:349-52. 2010..We aimed to study the prognostic value of NT-proBNP in hypertensive patients with LVH...
Comprehensive noninvasive arterial vascular evaluationJay N Cohn
Cardiovascular Division, Mayo Mail Code 508, Minneapolis, MN 55455, USA
Future Cardiol 5:573-9. 2009..This can provide insight into functional and structural abnormalities in the small as well as the large arteries, and may be useful in monitoring response to therapy...
Relationship between carotid artery stiffness index, BNP and high-sensitivity CRPG R Shroff
Cardiovascular Division, Medical School, University of Minnesota, Minneapolis, MN 55455, USA
J Hum Hypertens 23:783-7. 2009..Cardiovascular biomarkers are thus associated with functional parameters of the vascular tree...
Noninvasive measurements of arterial stiffness: repeatability and interrelationships with endothelial function and arterial morphology measuresCorey J Huck
School of Kinesiology, University of Minnesota, Minneapolis, MN 55455, USA
Vasc Health Risk Manag 3:343-9. 2007..Therefore, the purpose of this study was to examine the repeatability and interrelationships between 3 different techniques to measure arterial stiffness and to compare this with forearm-mediated dilation...
Effect of carvedilol, lisinopril and their combination on vascular and cardiac health in patients with borderline blood pressure: the DETECT StudyS M Saul
Cardiology Division, University of Minnesota Medical School, Minneapolis, MN, USA
J Hum Hypertens 27:362-7. 2013....
Clinical significance of a high ankle-brachial index: insights from the Atherosclerosis Risk in Communities (ARIC) StudyKeattiyoat Wattanakit
Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
Atherosclerosis 190:459-64. 2007..The clinical significance of a high ankle-brachial index (ABI), defined by the associated risk factor burden and ischemic risk, is largely unknown...
Comparison of changes in heart rate variability and blood pressure during nitroglycerin administration and head-up tilt testingTyler A Bosch
School of Kinesiology, University of Minnesota, 1900 University Avenue S E, Minneapolis, MN 55455, USA
Clin Auton Res 19:46-50. 2009..To compare the changes in heart rate variability (HRV) and blood pressure (BP) between standard head-up tilt test (HUT) and nitroglycerin administration...
Angiotensin II, platelets and oxidative stressDaniel A Duprez
J Hypertens 22:1085-6. 2004
Is the female heart more sensitive to aldosterone for early remodeling?Daniel A Duprez
Hypertension 43:936-7. 2004
Hypertension in peripheral arterial diseaseDenis L Clement
Department of Cardiovascular Diseases, University of Ghent, De Pintelaaan 185, B 9000 Gent, Belgium
Curr Pharm Des 10:3615-20. 2004..Therefore, treatment with antiplatelet drugs, ACE-inhibitors and statins should be considered...
Genetic variants of inflammatory markers and arterial stiffnessDaniel A Duprez
Hypertension 51:1472-3. 2008
Heart rate: an independent predictor for hypertension?Daniel A Duprez
J Hypertens 24:1711-3. 2006
Measuring endothelial dysfunctionDaniel A Duprez
J Hypertens 25:1513-4; author reply 1514-5. 2007
Prognostic value of ambulatory blood-pressure recordings in patients with treated hypertensionDenis L Clement
Department of Cardiovascular Diseases, Ghent University, Ghent, Belgium
N Engl J Med 348:2407-15. 2003....
Improving outcomes in post-acute myocardial infarction heart failure: incorporation of aldosterone blockade into combination therapy to optimize neurohormonal blockadeBertram Pitt
University of Michigan Medical Center, William Beaumont Hospital, Ann Arbor, Michigan 48109, USA
Am J Cardiol 97:26F-33F. 2006..To achieve needed improvements in outcomes in this population, early and consistent initiation of these evidence-based, guideline-recommended therapies in all eligible patients is crucial...
The eye, the mirror of the heartDaniel A Duprez
Eur Heart J 28:1915-6. 2007
Cardiac autonomic imbalance in pre-hypertension and in a family history of hypertensionDaniel A Duprez
J Am Coll Cardiol 51:1902-3. 2008
Research Grants
- Lipoproteins, HIV, and Antiretroviral Therapy in SMARTDaniel Duprez; Fiscal Year: 2007..This proposal will produce additional information that will enhance their disease-free survival rate. (End of Abstract) ..
