Cherie Dunphy

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi request reprint Evaluation of bone marrow specimens with acute myelogenous leukemia for CD34, CD15, CD117, and myeloperoxidase
    C H Dunphy
    Division of Hematopathology, Department of Pathology, St Louis University Health Sciences Center, St Louis, MO, USA
    Arch Pathol Lab Med 125:1063-9. 2001
  2. ncbi request reprint Biclonality versus intraclonal evolution of a single tumor cell clone in B-cell chronic lymphoproliferative disorders
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine CB 7525, University of North Carolina, Chapel Hill, NC, USA
    Haematologica 91:292A. 2006
  3. ncbi request reprint Gene expression profiling data in lymphoma and leukemia: review of the literature and extrapolation of pertinent clinical applications
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, The University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 130:483-520. 2006
  4. ncbi request reprint Pediatric CD56+ anaplastic large cell lymphoma: a review of the literature
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, CB 7525, UNC, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 130:1859-64. 2006
  5. ncbi request reprint The value of CD64 expression in distinguishing acute myeloid leukemia with monocytic differentiation from other subtypes of acute myeloid leukemia: a flow cytometric analysis of 64 cases
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, University of North Carolina, CB 7525, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 131:748-54. 2007
  6. ncbi request reprint Analysis of immunohistochemical markers in bone marrow sections to evaluate for myelodysplastic syndromes and acute myeloid leukemias
    Cherie H Dunphy
    Divisions of Hematopathology, Departments of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 15:154-9. 2007
  7. ncbi request reprint Correlation of plasma cell percentages by CD138 immunohistochemistry, cyclin D1 status, and CD56 expression with clinical parameters and overall survival in plasma cell myeloma
    Cherie Hilborn Dunphy
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 15:248-54. 2007
  8. doi request reprint Usefulness of routine conventional cytogenetic analysis in tissues submitted for "lymphoma work-up"
    Cherie Dunphy
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Leuk Lymphoma 49:75-80. 2008
  9. doi request reprint Reaction patterns of TRAP and DBA.44 in hairy cell leukemia, hairy cell variant, and nodal and extranodal marginal zone B-cell lymphomas
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 16:135-9. 2008
  10. pmc Primary mediastinal B-cell lymphoma: detection of BCL2 gene rearrangements by PCR analysis and FISH
    Cherie H Dunphy
    Divisions of Hematopathology, University of North Carolina, Chapel Hill, NC, USA
    J Hematop 1:77-84. 2008

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Evaluation of bone marrow specimens with acute myelogenous leukemia for CD34, CD15, CD117, and myeloperoxidase
    C H Dunphy
    Division of Hematopathology, Department of Pathology, St Louis University Health Sciences Center, St Louis, MO, USA
    Arch Pathol Lab Med 125:1063-9. 2001
    ..Some markers (CD34, CD15, and CD117) are available for both techniques. Myeloperoxidase (MPO) analysis may be performed by enzyme cytochemical (EC) or IH techniques...
  2. ncbi request reprint Biclonality versus intraclonal evolution of a single tumor cell clone in B-cell chronic lymphoproliferative disorders
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine CB 7525, University of North Carolina, Chapel Hill, NC, USA
    Haematologica 91:292A. 2006
  3. ncbi request reprint Gene expression profiling data in lymphoma and leukemia: review of the literature and extrapolation of pertinent clinical applications
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, The University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 130:483-520. 2006
    ..Gene expression (GE) analyses using microarrays have become an important part of biomedical and clinical research in hematolymphoid malignancies. However, the methods are time-consuming and costly for routine clinical practice...
  4. ncbi request reprint Pediatric CD56+ anaplastic large cell lymphoma: a review of the literature
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, CB 7525, UNC, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 130:1859-64. 2006
    ..The patient had initial lymph node and multiple sites of cutaneous involvement and an aggressive clinical course with multiple recurrences after varying periods of complete remission...
  5. ncbi request reprint The value of CD64 expression in distinguishing acute myeloid leukemia with monocytic differentiation from other subtypes of acute myeloid leukemia: a flow cytometric analysis of 64 cases
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, University of North Carolina, CB 7525, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 131:748-54. 2007
    ..However, in that study, the intensity of CD64 was not well defined and the number of non-M4/non-M5 AMLs was small...
  6. ncbi request reprint Analysis of immunohistochemical markers in bone marrow sections to evaluate for myelodysplastic syndromes and acute myeloid leukemias
    Cherie H Dunphy
    Divisions of Hematopathology, Departments of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 15:154-9. 2007
    ....
  7. ncbi request reprint Correlation of plasma cell percentages by CD138 immunohistochemistry, cyclin D1 status, and CD56 expression with clinical parameters and overall survival in plasma cell myeloma
    Cherie Hilborn Dunphy
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 15:248-54. 2007
    ....
  8. doi request reprint Usefulness of routine conventional cytogenetic analysis in tissues submitted for "lymphoma work-up"
    Cherie Dunphy
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Leuk Lymphoma 49:75-80. 2008
    ....
  9. doi request reprint Reaction patterns of TRAP and DBA.44 in hairy cell leukemia, hairy cell variant, and nodal and extranodal marginal zone B-cell lymphomas
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 16:135-9. 2008
    ..There is a high sensitivity of combined DBA.44/TRAP-positivity (+) in confirming HCL. A previous study of mucosa-associated lymphoid tissue lymphoma showed DBA.44+ in 10%, TRAP+ in 29%, and DBA.44+/TRAP+ in 5%...
  10. pmc Primary mediastinal B-cell lymphoma: detection of BCL2 gene rearrangements by PCR analysis and FISH
    Cherie H Dunphy
    Divisions of Hematopathology, University of North Carolina, Chapel Hill, NC, USA
    J Hematop 1:77-84. 2008
    ..Our results imply that a subset of PMBCL [(4 out of 24 analyzed) in our series] may be of GC origin. A larger study is necessary to determine any clinical significance...
  11. ncbi request reprint Evaluation of mast cells in myeloproliferative disorders and myelodysplastic syndromes
    Cherie H Dunphy
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill 27599 7525, USA
    Arch Pathol Lab Med 129:219-22. 2005
    ..Thus, it has been suggested that SMCD may represent one aspect of a hematologic disorder that involves multiple bone marrow lineages...
  12. ncbi request reprint Applications of flow cytometry and immunohistochemistry to diagnostic hematopathology
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill 27599 7525, USA
    Arch Pathol Lab Med 128:1004-22. 2004
    ..Advantages and disadvantages of these techniques are examined...
  13. doi request reprint Comparative analysis of detecting monocytic cells and their aberrancy
    Cherie H Dunphy
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 19:336-40. 2011
    ....
  14. ncbi request reprint Extranodal posttransplant plasmacytic hyperplasia with subsequent posttransplant plasmacytic malignancy: six-year interval case report and review of the literature
    Cherie H Dunphy
    Division of Hematopathology, St Louis University Health Sciences Center, MO, USA
    Arch Pathol Lab Med 126:351-6. 2002
    ..Since we have no data to support disseminated bony disease or an abnormal serum protein, we have not used the term "multiple myeloma" for this case...
  15. ncbi request reprint CD15(+) acute lymphoblastic leukemia and subsequent monoblastic leukemia: persistence of t(4;11) abnormality and B-cell gene rearrangement
    C H Dunphy
    Division of Hematopathology, Department of Pathology, St Louis University Health Sciences Center, St Louis University School of Medicine, St Louis, MO, USA
    Arch Pathol Lab Med 125:1227-30. 2001
    ..These findings support the concept that both processes arose from a multipotential progenitor cell...
  16. ncbi request reprint Mature B-cell acute lymphoblastic leukemia with associated translocations (14;18)(q32;q21) and (8;9)(q24;p13). A Burkitt variant?
    Cherie H Dunphy
    Department of Pathology and Laboratory Medicine, Division of Hematopathology, University of North Carolina, Chapel Hill 27599 7525, USA
    Arch Pathol Lab Med 127:610-3. 2003
    ..Additional cases need to be accrued and documented to determine the significance of an associated abnormality of 8q24 in this setting...
  17. ncbi request reprint Flow cytometric immunophenotyping in posttransplant lymphoproliferative disorders
    Cherie H Dunphy
    Division of Hematopathology, St Louis University Health Sciences Center, MO, USA
    Am J Clin Pathol 117:24-8. 2002
    ..However, 1 PBCL that was polyclonal by FCI was monoclonal by GS. Thus, FCI is useful for identifying a clonal process in PTLDs with negative results by GS; FCI and GS should be performed routinely in PTLDs to detect a clonal process...
  18. ncbi request reprint The role of Janus Kinase 2 V617F mutation in extramedullary hematopoiesis of the spleen in neoplastic myeloid disorders
    Pin Pen Hsieh
    Department of Pathology and Laboratory Medicine, The Methodist Hospital and The Methodist Hospital Research Institute, Houston, TX 77030, USA
    Mod Pathol 20:929-35. 2007
    ..Also, dysregulation of downstream pathways such as Bcl-xL may be important to CMPD disease pathogenesis in the spleen...
  19. ncbi request reprint Immunoreactivity of MIC2 (CD99) and terminal deoxynucleotidyl transferase in bone marrow clot and core specimens of acute myeloid leukemias and myelodysplastic syndromes
    Loveleen C Kang
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 130:153-7. 2006
    ..Although this study speculated that MIC2 expression was probably not limited to TdT-positive AML, there was no comparison with TdT reactivity in this study...
  20. ncbi request reprint Clinical course of thrombocytopenia in patients treated with imatinib mesylate for accelerated phase chronic myelogenous leukemia
    Hendrik W van Deventer
    Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Rm 3009 Old Clinic Building, Chapel Hill, NC 27599 7305, USA
    Am J Hematol 71:184-90. 2002
    ..Grade III-IV thrombocytopenia is common in accelerated phase CML and may be a marker for the inability to achieve cytogenetic response using single agent imatinib mesylate...
  21. doi request reprint Glut1 and Glut3 expression in lymphoma and their association with tumor intensity on 18F-fluorodeoxyglucose positron emission tomography
    Amir H Khandani
    Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7510, USA
    Nucl Med Commun 30:594-601. 2009
    ....
  22. ncbi request reprint Acute liver failure due to natural killer-like T-cell leukemia/lymphoma: a case report and review of the literature
    Evan S Dellon
    University of North Carolina School of Medicine, Division of Gastroenterology and Hepatology, CB 7080, Bioinformatics Bldg, Rm 1140, 130 Mason Farm Rd, Chapel Hill, NC 27599 7080, United States
    World J Gastroenterol 12:4089-92. 2006
    ..This case demonstrates that liver biopsy is essential in diagnosing unusual causes of acute liver failure, and that infiltration of the liver with NK-like T-cell lymphoma/leukemia can cause acute liver failure...
  23. ncbi request reprint Follicular lymphoma with a burkitt translocation--predictor of an aggressive clinical course: a case report and review of the literature
    Peter M Voorhees
    Department of Internal Medicine, Division of Hematology and Oncology, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 128:210-3. 2004
    ..Routine cytogenetic analysis is recommended at initial diagnosis of follicular lymphoma to better identify abnormalities that may predict prognosis and influence therapy...
  24. ncbi request reprint Relative contributions of enzyme cytochemistry and flow cytometric immunophenotyping to the evaluation of acute myeloid leukemias with a monocytic component and of flow cytometric immunophenotyping to the evaluation of absolute monocytoses
    Cherie H Dunphy
    Division of Hematopathology, McLendon Clinical Laboratories, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Am J Clin Pathol 122:865-74. 2004
    ..These FCI abnormalities in morphologically mature MCs might indicate markers for CMML. AMs revealed FCI abnormalities, indicating clues to their correct classification as CMML...
  25. ncbi request reprint Acute megakaryoblastic leukemia after transient myeloproliferative disorder with clonal karyotype evolution in a phenotypically normal neonate
    Jacek M Polski
    Department of Pathology, University of South Alabama College of Medicine, Mobile, USA
    J Pediatr Hematol Oncol 24:50-4. 2002
    ..The gradual clonal evolution of the blasts in our patient suggests that "multiple hits" oncogenesis applies to TMD progression to acute leukemia...
  26. ncbi request reprint Two cases of acute myeloid leukemia with t(11;17) associated with varying morphology and immunophenotype: rearrangement of the MLL gene and a region proximal to the RARalpha gene
    Loveleen C Kang
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, Campus Box 7525, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Cancer Genet Cytogenet 159:168-73. 2005
    ..These cases illustrate the importance of FISH analysis to confirm the presence of a particular recurring rearrangement...
  27. doi request reprint p38 mitogen-activated protein kinase has different degrees of activation in myeloproliferative disorders and myelodysplastic syndromes
    Munir Shahjahan
    Department of Pathology, Methodist Hospital and Methodist Research Institute, Houston, TX, USA
    Am J Clin Pathol 130:635-41. 2008
    ..007) cases. Increased p38 MAPK activation may have a role in inhibiting hematopoiesis leading to cytopenias in MDS, and relatively decreased p38 activation in MPD might promote hematopoiesis, resulting in cytosis...
  28. ncbi request reprint Fine needle aspiration biopsy of a posttransplant lymphoproliferative disorder with pronounced plasmacytic differentiation presenting in the face. A case report
    T Brent Ponder
    Department of Pathology, Saint Louis University School of Medicine, St Louis, Missouri, USA
    Acta Cytol 46:389-94. 2002
    ....
  29. ncbi request reprint Diagnosis of cervical thymoma by fine needle aspiration biopsy with flow cytometry. A case report
    T Brent Ponder
    Division Endocrinology, Department of Pathology, St Louis, Missouri, USA
    Acta Cytol 46:1129-32. 2002
    ..The diagnosis was rendered because, unlike in previous cases, flow cytometric immunophenotyping was performed...
  30. ncbi request reprint Burkitt lymphoma arising in organ transplant recipients: a clinicopathologic study of five cases
    Jerald Z Gong
    Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
    Am J Surg Pathol 27:818-27. 2003
    ..Genotypic and phenotypic aberrations are often present. Rituximab may be an effective alternative to conventional combination chemotherapy in the treatment of a posttransplant Burkitt lymphoma...
  31. ncbi request reprint Nodular lymphocyte predominant Hodgkin lymphoma at atypical locations may be associated with increased numbers of large cells and a diffuse histologic component
    David T Yang
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Am J Hematol 83:218-21. 2008
    ..From 55 cases of NLPHL, we describe a possible subset of NLPHL occurring in older individuals at atypical sites, associated with increased numbers of large cells, a diffuse histologic component, and expression of Bcl-2...
  32. ncbi request reprint Grading of follicular lymphoma: comparison of routine histology with immunohistochemistry
    Antonio E Martinez
    Division of Hematopathology, Department of Pathology and Laboratory Medicine, Lineberger Cancer Center, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Arch Pathol Lab Med 131:1084-8. 2007
    ....
  33. ncbi request reprint Recommended curriculum for teaching hematopathology to subspecialty hematopathology fellows
    Sherrie L Perkins
    Department of Pathology, University of Utah, Salt Lake City, UT 84132, USA
    Am J Clin Pathol 127:962-76. 2007
    ..This report also includes recommendations for training experiences that will facilitate the transition of subspecialty residents to practicing consultants in hematopathology...
  34. ncbi request reprint Ewing sarcoma/peripheral primitive neuroectodermal tumor: adult abdominal tumors with an Ewing sarcoma gene rearrangement demonstrated by fluorescence in situ hybridization in paraffin sections
    Laura J Gardner
    Division of Hematopathology, Department of Pathology, St Louis University Health Sciences Center, St Louis, Missouri, USA
    Appl Immunohistochem Mol Morphol 12:160-5. 2004
    ..Thus, the usefulness of FISH demonstration of an EWS gene rearrangement with these specific probes in such unusual cases is supported and is demonstrated in paraffin-embedded tissue...