Research Topics
| Lisa K DunnwaldSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
PET tumor metabolism in locally advanced breast cancer patients undergoing neoadjuvant chemotherapy: value of static versus kinetic measures of fluorodeoxyglucose uptakeLisa K Dunnwald
Division of Nuclear Medicine and Medical Oncology, University of Washington, Seattle, Washington 98109, USA
Clin Cancer Res 17:2400-9. 2011..Serial dynamic [(18)F]-FDG (fluorodeoxyglucose) PET scans were used to compare kinetic parameters with the standardized uptake value (SUV) as predictors of pathologic response, disease-free survival (DFS), and overall survival (OS)...- Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patientsLisa K Dunnwald
Department of Epidemiology, University of Washington, Box 356113, 1959 NE Pacific St, Seattle, WA 98195, USA
Breast Cancer Res 9:R6. 2007..However, few studies have evaluated variations in the risks of breast cancer-specific mortality across ER/PR status by either demographic or clinical characteristics... - Tumor metabolism and blood flow changes by positron emission tomography: relation to survival in patients treated with neoadjuvant chemotherapy for locally advanced breast cancerLisa K Dunnwald
Department of Bioengineering, Division of Nuclear Medicine, University of Washington, Seattle, WA, USA
J Clin Oncol 26:4449-57. 2008..Serial positron emission tomography (PET) has been shown to predict pathologic response in this setting. We evaluated serial quantitative PET tumor blood flow (BF) and metabolism as in vivo measurements to predict patient outcome... 
Residual tumor uptake of [99mTc]-sestamibi after neoadjuvant chemotherapy for locally advanced breast carcinoma predicts survivalLisa K Dunnwald
Division of Nuclear Medicine, Department of Radiology, University of Washington, Seattle, Washington 98195, USA
Cancer 103:680-8. 2005..Given the association between MIBI uptake and tumor blood flow, this prognostic capability may be related to retained tumor vascularity after treatment...- Serial 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) to monitor treatment of bone-dominant metastatic breast cancer predicts time to progression (TTP)Jennifer M Specht
Division of Medical Oncology, University of Washington School of Medicine, Seattle Cancer Care Alliance, 825 Eastlake Avenue E, G3 200, Seattle, WA 98109, USA
Breast Cancer Res Treat 105:87-94. 2007..Our goal was to evaluate the prognostic power of serial FDG PET in BD breast cancer patients undergoing treatment... - Changes in blood flow and metabolism in locally advanced breast cancer treated with neoadjuvant chemotherapyDavid A Mankoff
Division of Nuclear Medicine, University of Washington, Seattle, Washington 98195, USA
J Nucl Med 44:1806-14. 2003..To characterize in vivo tumor biology in patients with LABC, we performed serial measurements of blood flow and glucose metabolism in LABC patients over the course of neoadjuvant chemotherapy and compared measurements with response... - 18F-FDG kinetics in locally advanced breast cancer: correlation with tumor blood flow and changes in response to neoadjuvant chemotherapyJeffrey Tseng
Division of Nuclear Medicine, Department of Radiology, University of Washington, Seattle, Washington 98195-6113, USA
J Nucl Med 45:1829-37. 2004..Further work is needed to understand the tumor biology underlying these findings... - Association between serial dynamic contrast-enhanced MRI and dynamic 18F-FDG PET measures in patients undergoing neoadjuvant chemotherapy for locally advanced breast cancerSavannah C Partridge
Department of Radiology, University of Washington School of Medicine, Seattle, Washington 98109 1023, USA
J Magn Reson Imaging 32:1124-31. 2010.... - [Tc-99m]-sestamibi uptake and washout in locally advanced breast cancer are correlated with tumor blood flowDavid A Mankoff
Division of Nuclear Medicine, University of Washington, Seattle, WA, USA
Nucl Med Biol 29:719-27. 2002..To determine the influence of breast tumor blood flow on MIBI kinetics, we compared MIBI uptake and washout to [O-15]-water PET estimates of blood flow in patients with locally advanced breast cancer... - Tumor metabolism and blood flow as assessed by positron emission tomography varies by tumor subtype in locally advanced breast cancerJennifer M Specht
Medical Oncology and Nuclear Medicine, Department of Medicine, University of Washington, Seattle, Washington 98109, USA
Clin Cancer Res 16:2803-10. 2010..This analysis examines tumor metabolism and perfusion by tumor subtype... - Dynamic and static approaches to quantifying 18F-FDG uptake for measuring cancer response to therapy, including the effect of granulocyte CSFRobert K Doot
Department of Bioengineering, University of Washington, Seattle, Washington, USA
J Nucl Med 48:920-5. 2007..We tested whether chemotherapy and treatment with granulocyte colony-stimulating factor (CSF) changed the blood clearance curves and therefore affected the relationship between MRFDG and SUV... - Metabolic and vascular features of dynamic contrast-enhanced breast magnetic resonance imaging and (15)O-water positron emission tomography blood flow in breast cancerPeter R Eby
Department of Radiology, University of Washington, Seattle Cancer Care Alliance, 825 Eastlake Avenue East, G3 200, Seattle, WA 98109 1023, USA
Acad Radiol 15:1246-54. 2008.... - Internal mammary nodal chain drainage is a prognostic indicator in axillary node-positive breast cancerMichelle S Yao
Department of Radiation Oncology, University of Washington Medical School, Seattle, WA, USA
Ann Surg Oncol 14:2985-93. 2007..Internal mammary (IM) nodes are a potential site of breast lymphatic drainage. We examined the relationship between lymphoscintigraphic evidence of IM drainage and survival in early-stage breast cancer patients (pts)... - Quantitative fluoroestradiol positron emission tomography imaging predicts response to endocrine treatment in breast cancerHannah M Linden
Division of Medical Oncology, University of Washington, Seattle Cancer Care Alliance, Seattle, WA 98109, USA
J Clin Oncol 24:2793-9. 2006..We tested the ability of FES-PET imaging to predict response to salvage hormonal treatment in heavily pretreated metastatic breast cancer patients, predominantly treated with aromatase inhibitors... - Evaluation of the internal mammary lymph nodes by FDG-PET in locally advanced breast cancer (LABC)Jennifer R Bellon
Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA, USA
Am J Clin Oncol 27:407-10. 2004..FDG-PET appears to be a useful noninvasive modality to detect IM metastases in LABC. Pathologic verification in a prospective study is necessary to confirm these findings... - Blood flow and metabolism in locally advanced breast cancer: relationship to response to therapyDavid A Mankoff
Division of Nuclear Medicine, Box 346113, University of Washington, 1959 E Pacific Street, Seattle, WA 98195, USA
J Nucl Med 43:500-9. 2002.... - SUV varies with time after injection in (18)F-FDG PET of breast cancer: characterization and method to adjust for time differencesSylvain Beaulieu
Division of Nuclear Medicine, University of Washington Medical Center, Seattle, Washington 98195, USA
J Nucl Med 44:1044-50. 2003..A comparison method based on this finding appears feasible and may improve the usefulness of the SUV by providing a means of comparing SUV acquired at different times after injection... - Are we ready for dedicated breast imaging approaches?David A Mankoff
Division of Nuclear Medicine, Box 356113, Room NN203, University of Washington Medical Center, 1959 NE Pacific Street, Seattle, WA 98195, USA
J Nucl Med 44:594-5. 2003 - Detection of locoregional and distant recurrences in breast cancer patients by using FDG PETWilliam B Eubank
Department of Radiology S 113 RAD, Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108 1597, USA
Radiographics 22:5-17. 2002..FDG PET has been proved accurate in restaging cases of recurrent breast cancer and will likely aid in directing therapy in these cases... - Use of serial FDG PET to measure the response of bone-dominant breast cancer to therapyStephanie E Stafford
Division of Medical Oncology, University of Washington Medical Center, Seattle 98195, USA
Acad Radiol 9:913-21. 2002..01). CONCLUSION: Preliminary results indicate that serial whole-body FDG PET can help quantitatively assess the response of breast cancer bone metastases to therapy. Prospective trials are needed to further investigate its accuracy...