Rebecca A Dumont

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Targeted radiotherapy of prostate cancer with a gastrin-releasing peptide receptor antagonist is effective as monotherapy and in combination with rapamycin
    Rebecca A Dumont
    Department of Nuclear Medicine, University of Freiburg, Freiburg, Germany
    J Nucl Med 54:762-9. 2013
  2. pmc Noninvasive imaging of alphaVbeta3 function as a predictor of the antimigratory and antiproliferative effects of dasatinib
    Rebecca A Dumont
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095 6948, USA
    Cancer Res 69:3173-9. 2009
  3. pmc Derivation of a compartmental model for quantifying 64Cu-DOTA-RGD kinetics in tumor-bearing mice
    Gregory Z Ferl
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California 90095 6948, USA
    J Nucl Med 50:250-8. 2009
  4. doi request reprint Novel (64)Cu- and (68)Ga-labeled RGD conjugates show improved PET imaging of α(ν)β(3) integrin expression and facile radiosynthesis
    Rebecca A Dumont
    Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany
    J Nucl Med 52:1276-84. 2011
  5. doi request reprint Correlation of the genotype of paragangliomas and pheochromocytomas with their metabolic phenotype on 3,4-dihydroxy-6-18F-fluoro-L-phenylalanin PET
    H Christian Rischke
    Department of Nuclear Medicine, University of Freiburg, Freiburg, Germany
    J Nucl Med 53:1352-8. 2012
  6. doi request reprint Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100
    Franziska Leonhardt
    Department of Hematology and Oncology, FreiburgUniversity Medical Center, Albert Ludwigs University of Freiburg, Freiburg, Germany
    Blood 121:3307-18. 2013
  7. ncbi request reprint Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors
    Helen Su
    Department of Molecular Medicine and Pharmacology, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, 650 Charles Young Drive, Los Angeles, CA 90095, USA
    Clin Cancer Res 12:5659-67. 2006
  8. doi request reprint 18F-FDOPA PET and PET/CT accurately localize pheochromocytomas
    Farzin Imani
    Ahmanson Biological Imaging Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    J Nucl Med 50:513-9. 2009

Collaborators

Detail Information

Publications8

  1. doi request reprint Targeted radiotherapy of prostate cancer with a gastrin-releasing peptide receptor antagonist is effective as monotherapy and in combination with rapamycin
    Rebecca A Dumont
    Department of Nuclear Medicine, University of Freiburg, Freiburg, Germany
    J Nucl Med 54:762-9. 2013
    ..In addition, inhibition of the protein kinase mammalian target of rapamycin (mTOR) has been shown to sensitize various cancer cells to the effects of radiotherapy...
  2. pmc Noninvasive imaging of alphaVbeta3 function as a predictor of the antimigratory and antiproliferative effects of dasatinib
    Rebecca A Dumont
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095 6948, USA
    Cancer Res 69:3173-9. 2009
    ..50+/-17.68 mm(2) in controls; P=0.001). [(64)Cu]DOTA-c(RGDfK) may provide a sensitive means of monitoring tumor response to SFK inhibition in alpha(V)beta(3)-expressing cancers early in the course of therapy...
  3. pmc Derivation of a compartmental model for quantifying 64Cu-DOTA-RGD kinetics in tumor-bearing mice
    Gregory Z Ferl
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California 90095 6948, USA
    J Nucl Med 50:250-8. 2009
    ..To better understand the PET signal obtained with radiolabeled RGD peptides, we have constructed a compartmental model that can describe the time-activity curves in tumors after an intravenous injection...
  4. doi request reprint Novel (64)Cu- and (68)Ga-labeled RGD conjugates show improved PET imaging of α(ν)β(3) integrin expression and facile radiosynthesis
    Rebecca A Dumont
    Department of Nuclear Medicine, University Hospital Freiburg, Freiburg, Germany
    J Nucl Med 52:1276-84. 2011
    ..The development of (68)Ga-RGD peptides would be of great utility given the convenience of (68)Ga production and radiolabeling, and (64)Cu-RGD peptides allow for delayed imaging with potentially improved tumor-to-background ratios...
  5. doi request reprint Correlation of the genotype of paragangliomas and pheochromocytomas with their metabolic phenotype on 3,4-dihydroxy-6-18F-fluoro-L-phenylalanin PET
    H Christian Rischke
    Department of Nuclear Medicine, University of Freiburg, Freiburg, Germany
    J Nucl Med 53:1352-8. 2012
    ..Furthermore, we assessed whether the genotypes of pheochromocytomas and paragangliomas correlate with the uptake of (18)F-DOPA...
  6. doi request reprint Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100
    Franziska Leonhardt
    Department of Hematology and Oncology, FreiburgUniversity Medical Center, Albert Ludwigs University of Freiburg, Freiburg, Germany
    Blood 121:3307-18. 2013
    ..We identify negative regulation of GvHD-related neovascularization by miR-100, which indicates common pathomechanistic features of GvHD and ischemia...
  7. ncbi request reprint Monitoring tumor glucose utilization by positron emission tomography for the prediction of treatment response to epidermal growth factor receptor kinase inhibitors
    Helen Su
    Department of Molecular Medicine and Pharmacology, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, 650 Charles Young Drive, Los Angeles, CA 90095, USA
    Clin Cancer Res 12:5659-67. 2006
    ....
  8. doi request reprint 18F-FDOPA PET and PET/CT accurately localize pheochromocytomas
    Farzin Imani
    Ahmanson Biological Imaging Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    J Nucl Med 50:513-9. 2009
    ..Herein, we investigated the accuracy of PET using 3,4-dihydroxy-6-(18)F-fluoro-phenylalanine ((18)F-FDOPA), an amino acid transporter substrate, as an independent marker for detection of benign and malignant pheochromocytomas...