Peter Duesberg

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint AIDS since 1984: no evidence for a new, viral epidemic--not even in Africa
    Peter H Duesberg
    Department of Molecular and Cell Biology, UC Berkeley, CA 94720, USA
    Ital J Anat Embryol 116:73-92. 2011
  2. pmc Immortality of cancers: a consequence of inherent karyotypic variations and selections for autonomy
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, University of California at Berkeley, Berkeley, CA, USA
    Cell Cycle 12:783-802. 2013
  3. doi request reprint Origin of metastases: subspecies of cancers generated by intrinsic karyotypic variations
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, University of California at Berkeley, Berkeley, CA, USA
    Cell Cycle 11:1151-66. 2012
  4. ncbi request reprint Is carcinogenesis a form of speciation?
    Peter Duesberg
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA
    Cell Cycle 10:2100-14. 2011
  5. ncbi request reprint Cancer drug resistance: the central role of the karyotype
    Peter Duesberg
    Dept Mol and Cell Biol, Donner Laboratory, UC Berkeley, Berkeley, CA 94720, USA
    Drug Resist Updat 10:51-8. 2007
  6. ncbi request reprint Aneuploidy and cancer: from correlation to causation
    Peter Duesberg
    Department of Molecular and Cellular Biology, Donner Laboratory, UC Berkeley, Berkeley, Calif, USA
    Contrib Microbiol 13:16-44. 2006
  7. ncbi request reprint The chromosomal basis of cancer
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, UC Berkeley, Berkeley, CA 94720, USA
    Cell Oncol 27:293-318. 2005
  8. doi request reprint On the karyotypic origin and evolution of cancer cells
    Joshua M Nicholson
    Department of Molecular and Cell Biology, Donner Laboratory, University of California Berkeley, Berkeley, CA 94720, USA
    Cancer Genet Cytogenet 194:96-110. 2009
  9. ncbi request reprint Aneuploidy approaching a perfect score in predicting and preventing cancer: highlights from a conference held in Oakland, CA in January, 2004
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, University of California Berkeley, Berkeley, California, USA
    Cell Cycle 3:823-8. 2004
  10. ncbi request reprint Chromosomal alterations cause the high rates and wide ranges of drug resistance in cancer cells
    Ruhong Li
    Department of Molecular and Cell Biology, Donner Laboratory, University of California, Berkeley, Berkeley, CA 94720, USA
    Cancer Genet Cytogenet 163:44-56. 2005

Detail Information

Publications21

  1. ncbi request reprint AIDS since 1984: no evidence for a new, viral epidemic--not even in Africa
    Peter H Duesberg
    Department of Molecular and Cell Biology, UC Berkeley, CA 94720, USA
    Ital J Anat Embryol 116:73-92. 2011
    ....
  2. pmc Immortality of cancers: a consequence of inherent karyotypic variations and selections for autonomy
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, University of California at Berkeley, Berkeley, CA, USA
    Cell Cycle 12:783-802. 2013
    ....
  3. doi request reprint Origin of metastases: subspecies of cancers generated by intrinsic karyotypic variations
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, University of California at Berkeley, Berkeley, CA, USA
    Cell Cycle 11:1151-66. 2012
    ..They are generated from parental cancers by multiple simultaneous karyotypic rearrangements, much like new species. The species-specific individualities of metastases explain why so many searches for commonalities have been unsuccessful...
  4. ncbi request reprint Is carcinogenesis a form of speciation?
    Peter Duesberg
    Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, CA, USA
    Cell Cycle 10:2100-14. 2011
    ..But if the "aneuploidies" of cancers are in effect the karyotypes of new species, this paradox is solved...
  5. ncbi request reprint Cancer drug resistance: the central role of the karyotype
    Peter Duesberg
    Dept Mol and Cell Biol, Donner Laboratory, UC Berkeley, Berkeley, CA 94720, USA
    Drug Resist Updat 10:51-8. 2007
    ..We also adduce evidence that resistance of chronic myeloid leukemia against the drug imatinib is chromosomal, although it is widely believed to be due to mutation of a kinase...
  6. ncbi request reprint Aneuploidy and cancer: from correlation to causation
    Peter Duesberg
    Department of Molecular and Cellular Biology, Donner Laboratory, UC Berkeley, Berkeley, Calif, USA
    Contrib Microbiol 13:16-44. 2006
    ..Based on this article a similar one, entitled 'The chromosomal basis of cancer', has since been published by us in Cellular Oncology 2005;27:293-318...
  7. ncbi request reprint The chromosomal basis of cancer
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, UC Berkeley, Berkeley, CA 94720, USA
    Cell Oncol 27:293-318. 2005
    ....
  8. doi request reprint On the karyotypic origin and evolution of cancer cells
    Joshua M Nicholson
    Department of Molecular and Cell Biology, Donner Laboratory, University of California Berkeley, Berkeley, CA 94720, USA
    Cancer Genet Cytogenet 194:96-110. 2009
    ..In sum, genomes consisting of individual and flexible karyotypes explain the characteristic individuality, stability, and flexibility of cancers...
  9. ncbi request reprint Aneuploidy approaching a perfect score in predicting and preventing cancer: highlights from a conference held in Oakland, CA in January, 2004
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, University of California Berkeley, Berkeley, California, USA
    Cell Cycle 3:823-8. 2004
  10. ncbi request reprint Chromosomal alterations cause the high rates and wide ranges of drug resistance in cancer cells
    Ruhong Li
    Department of Molecular and Cell Biology, Donner Laboratory, University of California, Berkeley, Berkeley, CA 94720, USA
    Cancer Genet Cytogenet 163:44-56. 2005
    ..The degree of resistance was roughly proportional to the number of these aneusomies. Thus, aneuploidy is the primary cause of the high rates and wide ranges of drug resistance in cancer cells...
  11. ncbi request reprint Chromosomal chaos and cancer
    Peter Duesberg
    University of California, Berkeley, USA
    Sci Am 296:52-9. 2007
  12. ncbi request reprint Aneuploidy, the primary cause of the multilateral genomic instability of neoplastic and preneoplastic cells
    Peter Duesberg
    Dept Mol and Cell Biol, Donner Laboratory, UC Berkeley, Berkeley, CA 94720, USA
    IUBMB Life 56:65-81. 2004
    ..We conclude that the transition of stable diploid to unstable aneuploid cell species is the primary cause of preneoplastic and neoplastic genomic instability and of cancer, and that mutations are secondary...
  13. ncbi request reprint Multistep carcinogenesis: a chain reaction of aneuploidizations
    Peter Duesberg
    Department of Molecular and Cell Biology, Donner Laboratory, University of California Berkeley, Berkeley, CA 94720, USA
    Cell Cycle 2:202-10. 2003
    ..According to this hypothesis the many abnormal phenotypes of cancer are generated by abnormal dosages of thousands of aneuploid, but un-mutated genes...
  14. ncbi request reprint The chemical bases of the various AIDS epidemics: recreational drugs, anti-viral chemotherapy and malnutrition
    Peter Duesberg
    Donner Laboratory, University of California Berkeley, Berkeley, CA 94720, USA
    J Biosci 28:383-412. 2003
    ..The hypothesis predicts AIDS prevention by adequate nutrition and abstaining from drugs, and even cures by treating AIDS diseases with proven medications...
  15. ncbi request reprint Correspondence re: D. Zimonjic et al., Derivation of human tumor cells in vitro without widespread genomic instability. Cancer Res., 61: 8838-8844, 2001
    Ruhong Li
    Cancer Res 62:6345-8; author reply 6348-9. 2002
  16. doi request reprint Centrosome aberrations and G1 phase arrest after in vitro and in vivo treatment with the SRC/ABL inhibitor dasatinib
    Alice Fabarius
    III Medizinische Klinik, Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Wiesbadener Strasse 7 11, 68305 Mannheim, Germany
    Haematologica 93:1145-54. 2008
    ..Dasatinib is a multitargeted inhibitor of ABL, the SRC family, and other tyrosine kinases. We sought to evaluate the effects of this drug on cell proliferation, centrosomes, mitotic spindles, and cell cycle progression in vitro and in vivo...
  17. doi request reprint Specific clones of spontaneously evolving karyotypes generate individuality of cancers
    Alice Fabarius
    III Medizinische Klinik Mannheim of the University of Heidelberg at Mannheim, Wiesbadener Str 7 11, 68305 Mannheim, Germany
    Cancer Genet Cytogenet 180:89-99. 2008
    ..This answers the age-old question, why even cancers of the same kind do not have consistent karyotypes...
  18. ncbi request reprint Centrosome aberrations after nilotinib and imatinib treatment in vitro are associated with mitotic spindle defects and genetic instability
    Alice Fabarius
    III Medizinische Universitätsklinik, Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Germany
    Br J Haematol 138:369-73. 2007
    ..Our data suggest that distinct tyrosine kinases likewise targeted by both drugs are essential actuators in maintenance of centrosome and karyotype integrity...
  19. ncbi request reprint Does aneuploidy or mutation start cancer?
    Peter Duesberg
    Science 307:41. 2005
  20. ncbi request reprint [A denial with catastrophic consequences]
    Georg Klein
    Mikrobiologiskt och Tumörbiologiskt Centrum, Karolinska Institutet, Stockholm
    Lakartidningen 102:3694, 3697. 2005
  21. pmc Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea
    Alice Fabarius
    III Medizinische Klinik Mannheim, University of Heidelberg, Wiesbadener Strasse 7 11, 68305 Mannheim, Germany
    Proc Natl Acad Sci U S A 99:6778-83. 2002
    ..We conclude that specific aneusomies are necessary for carcinogenesis...