Species

Dongsheng Duan

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. Zhao J, Kodippili K, Yue Y, Hakim C, Wasala L, Pan X, et al. Dystrophin contains multiple independent membrane-binding domains. Hum Mol Genet. 2016;25:3647-3653 pubmed publisher
    ..Our results not only shed critical light on dystrophin biology and DMD pathogenesis, but also provide a foundation for rationally engineering minimized dystrophins for DMD gene therapy. ..
  2. Patel A, Zhao J, Yue Y, Zhang K, Duan D, Lai Y. Dystrophin R16/17-syntrophin PDZ fusion protein restores sarcolemmal nNOSĪ¼. Skelet Muscle. 2018;8:36 pubmed publisher
    ..Further, nNOS restoration was independent of the dystrophin-associated protein complex. Our results suggest that the R16/17-Syn PDZ fusion construct is sufficient to restore sarcolemmal nNOSĪ¼ in the dystrophin-null muscle. ..
  3. request reprint
    Duan D. Duchenne muscular dystrophy gene therapy in the canine model. Hum Gene Ther Clin Dev. 2015;: pubmed
    ..This review discusses the history, current status and future directions of the DMD gene therapy in the canine model. ..
  4. request reprint
    Duan D. Dystrophin gene replacement and gene repair therapy for Duchenne muscular dystrophy in 2016. Hum Gene Ther Clin Dev. 2016;: pubmed
    ..In light of rapid progress in this field, the Parent Project Muscular Dystrophy (PPMD) recently interviewed me on the current status of DMD gene therapy. Here I summarized the interview with PPMD. ..

Collaborators