Heng Du

Summary

Affiliation: University of Kansas
Country: USA

Publications

  1. pmc Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons
    Lan Guo
    Department of Pharmacology and Toxicology and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, KS, USA
    PLoS ONE 8:e54914. 2013
  2. pmc Identification of human ABAD inhibitors for rescuing Aβ-mediated mitochondrial dysfunction
    Koteswara R Valaasani
    2099 Constant Avenue, University of Kansas, Lawrence, KS 66047, USA
    Curr Alzheimer Res 11:128-36. 2014
  3. pmc Is amyloid binding alcohol dehydrogenase a drug target for treating Alzheimer's disease?
    Eva Borger
    School of Biology, Medical and Biological Sciences Building, North Haugh, University of St Andrews, Scotland UK KY16 9TF
    Curr Alzheimer Res 10:21-9. 2013
  4. pmc Synaptic mitochondrial pathology in Alzheimer's disease
    Heng Du
    Higuchi Bioscience Center, University of Kansas, Lawrence, Kansas, USA
    Antioxid Redox Signal 16:1467-75. 2012

Collaborators

  • Koteswara R Valaasani
  • Eva Borger
  • Lan Guo
  • Fang Du
  • Shirley S Yan
  • Emily A Carlson
  • Jianping Li
  • Gang Hu
  • Xueqi Gan
  • Yaopeng Guo
  • Qinru Sun
  • Xiaoping Wu
  • Laura Aitken
  • Shirley Shi Du Yan
  • John Xi Chen
  • Shiqiang Yan
  • Shirley ShiDu Yan
  • Frank J Gunn-Moore
  • Guy M McKhann
  • Wenshen Zhang

Detail Information

Publications4

  1. pmc Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons
    Lan Guo
    Department of Pharmacology and Toxicology and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, KS, USA
    PLoS ONE 8:e54914. 2013
    ..These findings provide new insights into CypD-dependent mitochondrial mPTP and signaling on mitochondrial trafficking in axons and synaptic degeneration in an environment enriched for Aβ...
  2. pmc Identification of human ABAD inhibitors for rescuing Aβ-mediated mitochondrial dysfunction
    Koteswara R Valaasani
    2099 Constant Avenue, University of Kansas, Lawrence, KS 66047, USA
    Curr Alzheimer Res 11:128-36. 2014
    ..Thus, these compounds are potential candidates for further pharmacologic development to target ABAD to improve mitochondrial function. ..
  3. pmc Is amyloid binding alcohol dehydrogenase a drug target for treating Alzheimer's disease?
    Eva Borger
    School of Biology, Medical and Biological Sciences Building, North Haugh, University of St Andrews, Scotland UK KY16 9TF
    Curr Alzheimer Res 10:21-9. 2013
    ..Here we review the evidence that the prevention of Aβ binding to ABAD is a drug target for the treatment of AD...
  4. pmc Synaptic mitochondrial pathology in Alzheimer's disease
    Heng Du
    Higuchi Bioscience Center, University of Kansas, Lawrence, Kansas, USA
    Antioxid Redox Signal 16:1467-75. 2012
    ..Thus, to understand the Aβ-associated synaptic mitochondrial perturbations would fortify our understanding of synaptic stress in the pathogenesis of AD...