C D'SOUZA-SCHOREY

Summary

Affiliation: University of Notre Dame
Country: USA

Publications

  1. ncbi request reprint ARF proteins: roles in membrane traffic and beyond
    CRISLYN D'SOUZA-SCHOREY
    Department of Biological Sciences and the Walther Cancer Institute, University of Notre Dame, Notre Dame, Indiana, USA
    Nat Rev Mol Cell Biol 7:347-58. 2006
  2. pmc Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis
    Cameron C Scott
    Division of Cell Biology, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    J Cell Biol 169:139-49. 2005
  3. ncbi request reprint Neurodegeneration in Niemann-Pick Type C disease and Huntington's disease: impact of defects in membrane trafficking
    J K Schweitzer
    Department of Biological Sciences and the Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556 0369, USA
    Curr Drug Targets 10:653-65. 2009
  4. pmc Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers
    CRISLYN D'SOUZA-SCHOREY
    Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA
    Genes Dev 26:1287-99. 2012
  5. ncbi request reprint Endocytic trafficking and Wnt/β-catenin signaling
    Oscar Pellon-Cardenas
    Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556 0369, USA
    Curr Drug Targets 12:1216-22. 2011
  6. pmc ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles
    Vandhana Muralidharan-Chari
    Department of Biological Sciences, University of Notre Dame, IN 46556, USA
    Curr Biol 19:1875-85. 2009
  7. pmc Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes
    Julie Ménétrey
    Centre de Recherche, UMR 144, Institut Curie, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    EMBO J 26:1953-62. 2007
  8. pmc ARF1-mediated actin polymerization produces movement of artificial vesicles
    Julien Heuvingh
    Centre de Recherche, Institut Curie, F 75248 Paris, France
    Proc Natl Acad Sci U S A 104:16928-33. 2007
  9. ncbi request reprint Spermatocyte cytokinesis requires rapid membrane addition mediated by ARF6 on central spindle recycling endosomes
    Naomi Dyer
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Development 134:4437-47. 2007
  10. doi request reprint Endosome positioning during cytokinesis
    Guillaume Montagnac
    Institut Curie, Centre de Recherche, Paris F 75248 France
    Biochem Soc Trans 36:442-3. 2008

Collaborators

  • Alice Dautry-Varsat
  • Florence Niedergang
  • A A Mironov
  • Philippe Chavrier
  • Thierry Dubois
  • Michel Franco
  • Chiara Recchi
  • Graca Raposo
  • Oscar Pellon-Cardenas
  • Vandhana Muralidharan-Chari
  • J K Schweitzer
  • Valerie Derrien
  • Mika Sakurai-Yageta
  • Guillaume Montagnac
  • Laurent Daviet
  • Julie Ménétrey
  • Naomi Dyer
  • Nadia Elkhatib
  • Julien Heuvingh
  • Jean Baptiste Sibarita
  • Jacques Camonis
  • Emma Colucci-Guyon
  • Olivia du Roure
  • Cameron C Scott
  • María Eugenia Balañá
  • Vincent Fraisier
  • Virginie Braun
  • Magali Prigent
  • Jill Schweitzer
  • J P Krivda
  • Maryse Romao
  • Carolyn Plou
  • James Clancy
  • Gaëlle Le Dez
  • Jérome Cicolari
  • Cécile Sykes
  • Elena Rebollo
  • Cayetano Gonzalez
  • Paloma Dominguez
  • Marcos Gonzalez-Gaitan
  • Mylene Perderiset
  • Fatima El Khadali
  • Anne Houdusse
  • Andres Alcover
  • Wendy Dobson
  • Theresia E B Stradal
  • Robert H Austin
  • Arthur S Alberts
  • David A Knecht
  • Olivia Paleotti
  • Maria Antonietta De Matteis
  • Agathe Subtil
  • Alexandre Saez
  • Natasha Coady-Osberg
  • Benoit Ladoux
  • Jun Peng
  • Pascal Silberzan
  • Bradley J Wallar
  • Roberto J Botelho
  • Axel Buguin
  • Philip Stahl
  • Colin Heath
  • Pascal Siberzan
  • Sergio Grinstein
  • Thierry Galli
  • Ilse Hurbain
  • Carine Rosse
  • Daniele Tenza
  • Carole Couillault
  • Remi Houlgatte
  • Philippe Montcourrier
  • Stéphanie Martineau

Detail Information

Publications22

  1. ncbi request reprint ARF proteins: roles in membrane traffic and beyond
    CRISLYN D'SOUZA-SCHOREY
    Department of Biological Sciences and the Walther Cancer Institute, University of Notre Dame, Notre Dame, Indiana, USA
    Nat Rev Mol Cell Biol 7:347-58. 2006
    ....
  2. pmc Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis
    Cameron C Scott
    Division of Cell Biology, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada
    J Cell Biol 169:139-49. 2005
    ..These observations suggest that hydrolysis of PI(4,5)P(2) dictates the remodeling of actin necessary for completion of phagocytosis...
  3. ncbi request reprint Neurodegeneration in Niemann-Pick Type C disease and Huntington's disease: impact of defects in membrane trafficking
    J K Schweitzer
    Department of Biological Sciences and the Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556 0369, USA
    Curr Drug Targets 10:653-65. 2009
    ..Here we discuss current therapies that seek to address cellular defects in NPC and HD and describe areas of investigation that may lead to new therapeutic treatment...
  4. pmc Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers
    CRISLYN D'SOUZA-SCHOREY
    Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, USA
    Genes Dev 26:1287-99. 2012
    ..Thus, new and improved strategies for microvesicle identification, isolation, and capture will have marked implications in point-of-care diagnostics for cancer patients...
  5. ncbi request reprint Endocytic trafficking and Wnt/β-catenin signaling
    Oscar Pellon-Cardenas
    Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556 0369, USA
    Curr Drug Targets 12:1216-22. 2011
    ..This review discusses the endocytic regulation of Wnt/β-catenin signaling that occurs at the cell surface as well as within the cell...
  6. pmc ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles
    Vandhana Muralidharan-Chari
    Department of Biological Sciences, University of Notre Dame, IN 46556, USA
    Curr Biol 19:1875-85. 2009
    ..Several studies have implicated the small GTP-binding protein ARF6 in tumor cell invasion, although the molecular basis by which ARF6 facilitates this process is unclear...
  7. pmc Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes
    Julie Ménétrey
    Centre de Recherche, UMR 144, Institut Curie, 26 Rue d Ulm, 75248 Paris Cedex 05, France
    EMBO J 26:1953-62. 2007
    ..Our data demonstrate that two well-known small GTPase-binding motifs, the PH domain and the alpha helical motif, can combine to create a novel mode of binding to Arfs...
  8. pmc ARF1-mediated actin polymerization produces movement of artificial vesicles
    Julien Heuvingh
    Centre de Recherche, Institut Curie, F 75248 Paris, France
    Proc Natl Acad Sci U S A 104:16928-33. 2007
    ..In addition to its well established function in coat recruitment, the ARF1 machinery also might produce movement- and fission-promoting forces through actin polymerization...
  9. ncbi request reprint Spermatocyte cytokinesis requires rapid membrane addition mediated by ARF6 on central spindle recycling endosomes
    Naomi Dyer
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany
    Development 134:4437-47. 2007
    ..We propose that ARF6 promotes rapid recycling of endosomal membrane stores during cytokinesis, which is critical for rapid cleavage furrow ingression...
  10. doi request reprint Endosome positioning during cytokinesis
    Guillaume Montagnac
    Institut Curie, Centre de Recherche, Paris F 75248 France
    Biochem Soc Trans 36:442-3. 2008
    ..Here, we discuss the possible mechanisms that drive the formation of endosomal clusters and the importance of this process for the targeted delivery of recycling membranes to the midbody...
  11. pmc The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
    Mika Sakurai-Yageta
    Institut Curie, Centre de Recherche, Paris F 75248, France
    J Cell Biol 181:985-98. 2008
    ..Based on these results, we propose that invadopodia function in tumor cells relies on the coordination of cytoskeletal assembly and exocytosis downstream of Rho guanosine triphosphatases...
  12. ncbi request reprint V-ATPase: a potential pH sensor
    Chiara Recchi
    Nat Cell Biol 8:107-9. 2006
  13. ncbi request reprint A role for mammalian diaphanous-related formins in complement receptor (CR3)-mediated phagocytosis in macrophages
    Emma Colucci-Guyon
    Membrane and Cytoskeleton Dynamics Group, Unite Mixte de Recherche 144, Centre National de la Recherche Scientifique Institut Curie, 75248 Paris, France
    Curr Biol 15:2007-12. 2005
    ..These results indicate a new function for mDia proteins in the regulation of actin polymerization during CR3-mediated phagocytosis...
  14. pmc ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages
    Florence Niedergang
    Membrane and Cytoskeleton Dynamics Laboratory, UMR144 CNRS, Institut Curie, 26 Rue d Ulm, F 75248 Paris Cedex 05, France
    J Cell Biol 161:1143-50. 2003
    ..This resulted in an early blockade in pseudopod extension and accumulation of intracellular vesicles, as observed by electron microscopy. We conclude that ARF6 is a major regulator of membrane recycling during phagocytosis...
  15. pmc ARF6 controls post-endocytic recycling through its downstream exocyst complex effector
    Magali Prigent
    Membrane and Cytoskeleton Dynamics Group, UMR144 Centre National de la Recherche Scientifique, Institut Curie, 26 Rue d Ulm, F 75248 Paris Cedex 05, France
    J Cell Biol 163:1111-21. 2003
    ..Our paper suggests that ARF6 specifies delivery and insertion of recycling membranes to regions of dynamic reorganization of the plasma membrane through interaction with the vesicle-tethering exocyst complex...
  16. ncbi request reprint Signaling and membrane dynamics during phagocytosis: many roads lead to the phagos(R)ome
    Florence Niedergang
    Membrane and Cytoskeleton Dynamics Group, Institut Curie, CNRS UMR144, 75248 Paris, France
    Curr Opin Cell Biol 16:422-8. 2004
    ..This ensures that the phagosome is rapidly provided with the machinery appropriate for later phagocytic functions, including particle degradation and antigen presentation...
  17. pmc TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages
    Virginie Braun
    Membrane and Cytoskeleton Dynamics Group, UMR144 CNRS Institut Curie, rue d Ulm 75248 Paris, France
    EMBO J 23:4166-76. 2004
    ..Therefore, TI-VAMP defines a new pathway of membrane delivery required for optimal FcR-mediated phagocytosis...
  18. pmc Force mapping in epithelial cell migration
    Olivia du Roure
    Laboratoire de Biorheologie et d Hydrodynamique Physico Chimique, Unité Mixte de Recherche Centre National de la Recherche Scientifique 7057, Centre National de la Recherche Scientifique FR2438, Universite Paris, 75251 Paris Cedex 05, France
    Proc Natl Acad Sci U S A 102:2390-5. 2005
    ..Maximal-traction stresses at the edge of a monolayer correspond to higher values than those measured for a single cell and may be due to a collective behavior...
  19. ncbi request reprint Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics
    Thierry Dubois
    Membrane and Cytoskeleton Dynamics Group, Institut Curie, CNRS UMR144, 75248 Paris, France
    Nat Cell Biol 7:353-64. 2005
    ..Our results establish a role for ARHGAP10 in Golgi structure and function at the crossroads between ARF1 and Cdc42 signalling pathways...
  20. ncbi request reprint ARF6 GTPase controls bacterial invasion by actin remodelling
    María Eugenia Balañá
    Unite de Biologie des Interactions Cellulaires, Institut Pasteur, CNRS URA 2582, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    J Cell Sci 118:2201-10. 2005
    ..These results indicate that ARF6, which controls membrane delivery during phagocytosis of red blood cells in macrophages, has a different role in the entry of this small bacterium, controlling cytoskeletal reorganization...
  21. ncbi request reprint [ARHGAP10, a novel RhoGAP at the cross-road between ARF1 and Cdc42 pathways, regulates Arp2/3 complex and actin dynamics on Golgi membranes]
    Thierry Dubois
    Laboratoire de la dynamique du cytosquelette et de la membrane, CNRS UMR 144, Institut Curie, 26 Rue d Ulm, 75248 Paris, France
    Med Sci (Paris) 21:692-4. 2005
  22. ncbi request reprint A conserved C-terminal domain of EFA6-family ARF6-guanine nucleotide exchange factors induces lengthening of microvilli-like membrane protrusions
    Valerie Derrien
    Laboratoire de la Dynamique de la Membrane et du Cytosquelette, UMR 144, Centre National de la Recherche Scientifique, Institut Curie, Section Recherche 26 rue d Ulm, 75241 Paris Cedex 5, France
    J Cell Sci 115:2867-79. 2002
    ....