Douglas Drossman

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. doi request reprint Diagnosis, characterization, and 3-month outcome after detoxification of 39 patients with narcotic bowel syndrome
    Douglas A Drossman
    Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Am J Gastroenterol 107:1426-40. 2012
  2. pmc Complementary and alternative medicine use and cost in functional bowel disorders: a six month prospective study in a large HMO
    Miranda A L Van Tilburg
    Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina, Chapel Hill, North Carolina, USA
    BMC Complement Altern Med 8:46. 2008
  3. pmc International survey of patients with IBS: symptom features and their severity, health status, treatments, and risk taking to achieve clinical benefit
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7080, USA
    J Clin Gastroenterol 43:541-50. 2009
  4. doi request reprint A focus group assessment of patient perspectives on irritable bowel syndrome and illness severity
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Division of Gastroenterology and Hepatology, University of North Carolina, 4150 Bioinformatics Building CB 7080, Chapel Hill, NC 27599 7080, USA
    Dig Dis Sci 54:1532-41. 2009
  5. doi request reprint Clinical trial: lubiprostone in patients with constipation-associated irritable bowel syndrome--results of two randomized, placebo-controlled studies
    D A Drossman
    University of North Carolina Center for Functional Gl and Mobility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Aliment Pharmacol Ther 29:329-41. 2009
  6. ncbi request reprint Review article: an integrated approach to the irritable bowel syndrome
    D A Drossman
    UNC Functional GI Disorders Center, University of North Carolina at Chapel Hill 27599 7080, USA
    Aliment Pharmacol Ther 13:3-14. 1999
  7. ncbi request reprint The functional gastrointestinal disorders and the Rome III process
    Douglas A Drossman
    Division of Gastroenterology and Hepatology, UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Gastroenterology 130:1377-90. 2006
  8. doi request reprint Severe and refractory chronic abdominal pain: treatment strategies
    Douglas A Drossman
    Division of Gastroenterology and Hepatology, UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Clin Gastroenterol Hepatol 6:978-82. 2008
  9. ncbi request reprint Introduction. The Rome Foundation and Rome III
    D A Drossman
    Rome Foundation and UNC Center for Functional GI and Motility Disorders, Chapel Hill, NC 27599, USA
    Neurogastroenterol Motil 19:783-6. 2007
  10. ncbi request reprint Alterations of brain activity associated with resolution of emotional distress and pain in a case of severe irritable bowel syndrome
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Division of Digestive Diseases and Department of Radiology and Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Gastroenterology 124:754-61. 2003

Research Grants

  1. MULTICENTER TRIAL OF FUNCTIONAL BOWEL DISORDERS
    Douglas Drossman; Fiscal Year: 2001

Detail Information

Publications69

  1. doi request reprint Diagnosis, characterization, and 3-month outcome after detoxification of 39 patients with narcotic bowel syndrome
    Douglas A Drossman
    Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Am J Gastroenterol 107:1426-40. 2012
    ..This study evaluated the clinical and psychosocial features of patients with NBS and the response to detoxification treatment...
  2. pmc Complementary and alternative medicine use and cost in functional bowel disorders: a six month prospective study in a large HMO
    Miranda A L Van Tilburg
    Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina, Chapel Hill, North Carolina, USA
    BMC Complement Altern Med 8:46. 2008
    ..The aim of this study is to determine prevalence, types and costs of CAM in IBS, functional diarrhea, functional constipation, and functional abdominal pain...
  3. pmc International survey of patients with IBS: symptom features and their severity, health status, treatments, and risk taking to achieve clinical benefit
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7080, USA
    J Clin Gastroenterol 43:541-50. 2009
    ..These factors are not fully understood...
  4. doi request reprint A focus group assessment of patient perspectives on irritable bowel syndrome and illness severity
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Division of Gastroenterology and Hepatology, University of North Carolina, 4150 Bioinformatics Building CB 7080, Chapel Hill, NC 27599 7080, USA
    Dig Dis Sci 54:1532-41. 2009
    ..This study confirms the heterogeneous and multi-component nature of IBS. These qualitative data can be used in developing health status and severity instruments for larger-scale studies...
  5. doi request reprint Clinical trial: lubiprostone in patients with constipation-associated irritable bowel syndrome--results of two randomized, placebo-controlled studies
    D A Drossman
    University of North Carolina Center for Functional Gl and Mobility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Aliment Pharmacol Ther 29:329-41. 2009
    ..Effective treatments for irritable bowel syndrome with constipation (IBS-C) are lacking...
  6. ncbi request reprint Review article: an integrated approach to the irritable bowel syndrome
    D A Drossman
    UNC Functional GI Disorders Center, University of North Carolina at Chapel Hill 27599 7080, USA
    Aliment Pharmacol Ther 13:3-14. 1999
    ..Newer medications acting at the 5-HT receptor may help in reducing pain and bowel dysfunction. For more severe pain, antidepressants may be considered...
  7. ncbi request reprint The functional gastrointestinal disorders and the Rome III process
    Douglas A Drossman
    Division of Gastroenterology and Hepatology, UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Gastroenterology 130:1377-90. 2006
  8. doi request reprint Severe and refractory chronic abdominal pain: treatment strategies
    Douglas A Drossman
    Division of Gastroenterology and Hepatology, UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Clin Gastroenterol Hepatol 6:978-82. 2008
  9. ncbi request reprint Introduction. The Rome Foundation and Rome III
    D A Drossman
    Rome Foundation and UNC Center for Functional GI and Motility Disorders, Chapel Hill, NC 27599, USA
    Neurogastroenterol Motil 19:783-6. 2007
  10. ncbi request reprint Alterations of brain activity associated with resolution of emotional distress and pain in a case of severe irritable bowel syndrome
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Division of Digestive Diseases and Department of Radiology and Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Gastroenterology 124:754-61. 2003
    ..We also found that clinical and psychosocial improvement was associated with reduced cingulate activation...
  11. ncbi request reprint Rome III: the new criteria
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, University of North Carolina, Chapel Hill, NC 27599, USA
    Chin J Dig Dis 7:181-5. 2006
    ....
  12. doi request reprint Severity in irritable bowel syndrome: a Rome Foundation Working Team report
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Chapel Hill, North Carolina 27599 7080, USA
    Am J Gastroenterol 106:1749-59; quiz 1760. 2011
    ..The aims of the Rome Foundation Working Team Committee were to summarize current research, to develop a consensus of understanding on this concept, and to make recommendations for its use in research and clinical care...
  13. doi request reprint Abuse, trauma, and GI illness: is there a link?
    Douglas A Drossman
    Division of Gastroenterology and Hepatology, UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7080, USA
    Am J Gastroenterol 106:14-25. 2011
    ....
  14. ncbi request reprint Effects of coping on health outcome among women with gastrointestinal disorders
    D A Drossman
    Department of Medicine, University of North Carolina, Chapel Hill 27599 7080, USA
    Psychosom Med 62:309-17. 2000
    ..Studies have shown that the nature and quality of coping may positively or negatively affect health outcome; however, this relationship has not been well studied among patients with gastrointestinal (GI) disorders...
  15. pmc Psychosocial aspects of the functional gastrointestinal disorders
    D A Drossman
    Division of Digestive Diseases, University of North Carolina, Chapel Hill 27599 7080, USA
    Gut 45:II25-30. 1999
    ..Review of treatment trials indicates clear support for psychotherapeutic treatments, especially in the long term, as well as some evidence for the benefit of antidepressants in FGID, even in the absence of improvements in mood...
  16. doi request reprint Randomized controlled trial shows biofeedback to be superior to pelvic floor exercises for fecal incontinence
    Steve Heymen
    Department of Medicine Division of Gastroenterology and Hepatology and Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina, Chapel Hill, North Carolina 27599 7080, USA
    Dis Colon Rectum 52:1730-7. 2009
    ..This study aimed to compare manometric biofeedback with pelvic floor exercises for the treatment of fecal incontinence in a randomized controlled trial controlling for nonspecific treatment effects...
  17. ncbi request reprint Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Division of Digestive Diseases, University of North Carolina at Chapel Hill, 27599 7080, USA
    Gastroenterology 125:19-31. 2003
    ..We also evaluated the amenability of clinically meaningful subgroups to these treatments...
  18. ncbi request reprint Characterization of health related quality of life (HRQOL) for patients with functional bowel disorder (FBD) and its response to treatment
    Douglas Drossman
    The UNC Center for Functional GI and Motility Disorders, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Am J Gastroenterol 102:1442-53. 2007
    ....
  19. doi request reprint Effect of abuse history on pain reports and brain responses to aversive visceral stimulation: an FMRI study
    Yehuda Ringel
    UNC Center for Functional GI and Motility Disorders, University of North Carolina, Chapel Hill, North Carolina, USA
    Gastroenterology 134:396-404. 2008
    ..These effects may be mediated by enhanced responses to aversive visceral stimuli. We investigated the effects of IBS and abuse history on pain reporting and brain activation in response to rectal distentions...
  20. ncbi request reprint Further characterization of painful constipation (PC): clinical features over one year and comparison with IBS
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Room 4150 Burnett Womack CB No 7080, Chapel Hill, NC 27599 7080, USA
    J Clin Gastroenterol 42:1080-8. 2008
    ....
  21. doi request reprint Commentary: sociocultural factors in medicine and gastrointestinal research
    Douglas A Drossman
    University of North Carolina, 420 Burnett Womack Building CB7080, Chapel Hill, NC 27599 3380, USA
    Eur J Gastroenterol Hepatol 20:593-5. 2008
    ..An understanding of specific cultural contributions to symptom experience can enhance the clinician's ability to engage in more effective research and treatment...
  22. ncbi request reprint Psychiatric and psychological dysfunction in irritable bowel syndrome and the role of psychological treatments
    Olafur S Palsson
    Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Campus Box 7080, Bioinformatics Building, Chapel Hill, NC 27599 7080, USA
    Gastroenterol Clin North Am 34:281-303. 2005
    ....
  23. doi request reprint Validation of symptom-based diagnostic criteria for irritable bowel syndrome: a critical review
    William E Whitehead
    Center for Functional Gastrointestinal and Motility Disorders, and Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Am J Gastroenterol 105:814-20; quiz 813, 821. 2010
    ..There are no consistent differences in sensitivity or specificity between Manning, Rome I, and Rome II. Both study types support the validity of symptom-based IBS criteria. Tests of Rome III are needed...
  24. ncbi request reprint What does the future hold for irritable bowel syndrome and the functional gastrointestinal disorders?
    Douglas A Drossman
    Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7080, USA
    J Clin Gastroenterol 39:S251-6. 2005
    ..The focus of this presentation is to address the advances that have recently occurred that set the stage for proposing future research to help move the field along and ultimately to help our patients...
  25. ncbi request reprint A prospective assessment of bowel habit in irritable bowel syndrome in women: defining an alternator
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Room 1110 Burnett Womack CB 7080, Chapel Hill, North Carolina 27599 7080, USA
    Gastroenterology 128:580-9. 2005
    ..There is no standard definition of an alternator (IBS-A), in which bowel habit changes over time. Our aim was to use Rome II criteria to prospectively assess change in bowel habit for more than 1 year to understand IBS-A...
  26. ncbi request reprint Irritable bowel syndrome: classification and conceptualization
    Yehuda Ringel
    Division of Digestive Diseases and Nutrition, Department of Medicine, University of North Carolina at Chapel Hill, 778 Burnett Womack, CB 7080, Chapel Hill, NC 27599 7080, USA
    J Clin Gastroenterol 35:S7-10. 2002
    ..g., abuse history), and maladaptive coping may amplify the clinical expression of the disorder and its outcome. Currently, clinical outcome has become understood in terms of global symptom relief and health-related quality of life...
  27. doi request reprint Cognitive factors affect treatment response to medical and psychological treatments in functional bowel disorders
    Stephan R Weinland
    Division of Gastroenterology and Hepatology, UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Am J Gastroenterol 105:1397-406. 2010
    ..Factors that determine clinical response aside from treatment itself are unknown. The aim of this study was to determine what baseline and post-treatment factors affect treatment response...
  28. doi request reprint Randomized, double-blind, placebo-controlled trial of the 5-HT1A receptor antagonist AZD7371 tartrate monohydrate (robalzotan tartrate monohydrate) in patients with irritable bowel syndrome
    Douglas A Drossman
    Division of Gastroenterology and Hepatology, University of North Carolina Center for Functional GI and Motility Disorders, Chapel Hill, North Carolina 27599 7080, USA
    Am J Gastroenterol 103:2562-9. 2008
    ..To investigate the efficacy and safety of the 5-hydroxytrypamine 1A (5-HT(1A)) receptor antagonist AZD7371 tartrate monohydrate (robalzotan tartrate monohydrate), termed AZD7371 here, in patients with irritable bowel syndrome (IBS)...
  29. ncbi request reprint Relationship of abuse history to functional gastrointestinal disorders and symptoms: some possible mediating mechanisms
    Jane Leserman
    UNC School of Medicine, University of North Carolina at Chapel Hill, USA
    Trauma Violence Abuse 8:331-43. 2007
    ..Given the high prevalence of abuse and long-lasting health consequences, referral for psychiatric and psychological treatment makes sense for many patients with abuse history seen within medical settings...
  30. pmc The narcotic bowel syndrome: clinical features, pathophysiology, and management
    David M S Grunkemeier
    Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina, USA
    Clin Gastroenterol Hepatol 5:1126-39; quiz 1121-2. 2007
    ....
  31. doi request reprint Irritable bowel syndrome subtypes defined by Rome II and Rome III criteria are similar
    Spencer D Dorn
    UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7080, USA
    J Clin Gastroenterol 43:214-20. 2009
    ..The implications of the Rome III recommendations to change the irritable bowel syndrome (IBS) subtype criteria for stool pattern are unknown...
  32. ncbi request reprint AGA technical review on irritable bowel syndrome
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, Division of Digestive Diseases, University of North Carolina, Chapel Hill, USA
    Gastroenterology 123:2108-31. 2002
  33. doi request reprint Contributions of pain sensitivity and colonic motility to IBS symptom severity and predominant bowel habits
    Motoyori Kanazawa
    Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, North Carolina, USA
    Am J Gastroenterol 103:2550-61. 2008
    ..Aims were to determine whether predominant bowel habits and IBS symptom severity are related to pain sensitivity, colon motility, or smooth muscle tone...
  34. doi request reprint Psychosocial factors are more important than disease activity in determining gastrointestinal symptoms and health status in adults at a celiac disease referral center
    Spencer D Dorn
    Center for Functional GI and Motility Disorders, University of North Carolina, Chapel Hill, NC, USA
    Dig Dis Sci 55:3154-63. 2010
    ..In adult patients with (CD), we studied the relationships among demographics, psychosocial factors, and disease activity with health-related quality of life (HRQOL), health care utilization, and symptoms...
  35. ncbi request reprint Randomized, controlled trial shows biofeedback to be superior to alternative treatments for patients with pelvic floor dyssynergia-type constipation
    Steve Heymen
    UNC Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Dis Colon Rectum 50:428-41. 2007
    ....
  36. ncbi request reprint Clinical response to tricyclic antidepressants in functional bowel disorders is not related to dosage
    Albena Halpert
    UNC Center for Functional GI and Motility Disorders, Chapel Hill, North Carolina, USA
    Am J Gastroenterol 100:664-71. 2005
    ..However, in FBD, it is not known whether plasma levels at the lower dosage are similarly related to a clinical response...
  37. ncbi request reprint Functional abdominal pain syndrome
    Douglas A Drossman
    UNC Center for Functional GI and Motility Disorders, University of North Carolina School of Medicine at Chapel Hill, USA
    Clin Gastroenterol Hepatol 2:353-65. 2004
    ..In refractory cases, referral to a multidisciplinary pain treatment center might be helpful...
  38. ncbi request reprint Regional brain activation in response to rectal distension in patients with irritable bowel syndrome and the effect of a history of abuse
    Yehuda Ringel
    UNC Center for Functional GI and Motility Disorders, University of North Carolina, Department of Medicine, Chapel Hill, North Carolina 27599 7080, USA
    Dig Dis Sci 48:1774-81. 2003
    ..The observations on the effect of abuse suggest a possible modulating role of abuse history on this brain response...
  39. pmc A very low-carbohydrate diet improves symptoms and quality of life in diarrhea-predominant irritable bowel syndrome
    Gregory L Austin
    Division of Gastroenterology and Hepatology, University of Colorado Denver, 12631 East 17th Avenue, Room 7609, Aurora, Colorado 80045, USA
    Clin Gastroenterol Hepatol 7:706-708.e1. 2009
    ..Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) anecdotally report symptom improvement after initiating a very low-carbohydrate diet (VLCD). This study prospectively evaluated a VLCD in IBS-D...
  40. doi request reprint Quality of life measures in irritable bowel syndrome
    Reuben K M Wong
    University of North Carolina Chapel Hill, NC 27599 7080, USA
    Expert Rev Gastroenterol Hepatol 4:277-84. 2010
    ..Finally, the IBS-specific HRQoL measures are described in detail, with an emphasis on their development, content and validation...
  41. pmc Increased colonic pain sensitivity in irritable bowel syndrome is the result of an increased tendency to report pain rather than increased neurosensory sensitivity
    Spencer D Dorn
    Center for Functional GI and Motility Disorders, University of North Carolina, Campus Box 7080, Chapel Hill, NC 27599 7080, USA
    Gut 56:1202-9. 2007
    ..The aim was to determine whether lower visceral pain thresholds in irritable bowel syndrome (IBS) primarily reflect physiological or psychological factors...
  42. doi request reprint Here's my phone number, don't call me: physician accessibility in the cell phone and e-mail era
    Reuben K M Wong
    Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    Dig Dis Sci 55:662-7. 2010
    ..We suggest a framework with guidelines on establishing and maintaining remote accessibility with patients in the context of a productive physician-patient relationship...
  43. ncbi request reprint Perceptions of physicians and patients with organic and functional gastrointestinal diagnoses
    Christine B Dalton
    University of North Carolina Center for Functional GI and Motility Disorders, Chapel Hill, North Carolina, USA
    Clin Gastroenterol Hepatol 2:121-6. 2004
    ..We studied patient after-hours telephone calls to gastrointestinal (GI) fellows at a university program to determine requests made, physicians' responses, and perceptions of patients and physicians to these requests...
  44. pmc Not all side effects associated with tricyclic antidepressant therapy are true side effects
    Syed Thiwan
    Division of Gastroenterology and Hepatology, University of North Carolina Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina, Chapel Hill, North Carolina 27599 7080, USA
    Clin Gastroenterol Hepatol 7:446-51. 2009
    ....
  45. ncbi request reprint Functional versus organic: an inappropriate dichotomy for clinical care
    Douglas A Drossman
    Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Am J Gastroenterol 101:1172-5. 2006
  46. ncbi request reprint Rome III: New standard for functional gastrointestinal disorders
    Douglas A Drossman
    Division of Gastroenterology and Hepatology, UNC Center for Functional GI and Motility Disorders, Chapel Hill, NC, USA
    J Gastrointestin Liver Dis 15:237-41. 2006
    ..In this issue of J Gastrointestin Liver Dis, these Guidelines, the Rome III, are presented. Also included are some of the differences between Rome II and Rome III criteria as well as the rationale for publishing this new version...
  47. doi request reprint Atypical antipsychotic quetiapine in the management of severe refractory functional gastrointestinal disorders
    Madhusudan Grover
    Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7080, USA
    Dig Dis Sci 54:1284-91. 2009
    ..This response in otherwise refractory patients suggests quetiapine might augment the effectiveness of antidepressants in severe FGIDs...
  48. ncbi request reprint Flexible sigmoidoscopy: the patients' perception
    Yehuda Ringel
    UNC Center for Functional GI and Motility Disorders, Division of Digestive Diseases, 778 Burnett Womack Bldg, CB 7080, University of North Carolina, Chapel Hill, NC 27599 7080, USA
    Gastrointest Endosc 55:315-20. 2002
    ..This study evaluated how patients perceive flexible sigmoidoscopy...
  49. doi request reprint The functional-organic dichotomy: postinfectious irritable bowel syndrome and inflammatory bowel disease-irritable bowel syndrome
    Madhusudan Grover
    Center for Functional GI and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7080, USA
    Clin Gastroenterol Hepatol 7:48-53. 2009
    ..It obligates us to reframe our understanding of illness and disease from the dualistic biomedical model into a more integrated biopsychosocial (BPS) perspective...
  50. ncbi request reprint Primary endpoints for irritable bowel syndrome trials: a review of performance of endpoints
    Michael Camilleri
    CENTER Program, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 5:534-40. 2007
    ....
  51. ncbi request reprint Severe irritable bowel and functional abdominal pain syndromes: managing the patient and health care costs
    George F Longstreth
    Kaiser Medical Center Medical Care Plan, 4647 Zion Avenue, San Diego, CA 92129, USA
    Clin Gastroenterol Hepatol 3:397-400. 2005
  52. ncbi request reprint Psychosocial aspects of the functional gastrointestinal disorders
    Rona L Levy
    University of Washington, Seattle, Washington 98105, USA
    Gastroenterology 130:1447-58. 2006
    ..More extensive physician training is needed if these aspects of treatment are to be used effectively and widely in clinical practice...
  53. ncbi request reprint Functional abdominal pain syndrome
    Ray E Clouse
    Division of Gastroenterology, Washington University, St Louis, Missouri 63110, USA
    Gastroenterology 130:1492-7. 2006
    ..Psychological treatment options include psychotherapy, relaxation techniques, and hypnosis. Refractory FAPS patients may benefit from a multidisciplinary pain clinic approach...
  54. ncbi request reprint Neurotrophin-3 improves functional constipation
    Henry P Parkman
    Temple University Hospital, Philadelphia, Pennsylvania 19140, USA
    Am J Gastroenterol 98:1338-47. 2003
    ..Our aim was to assess 1) the dose-related effects of NT-3 on bowel function, colon transit, and symptoms of chronic constipation, and 2) its safety...
  55. ncbi request reprint Psychosocial factors and the disorders of GI function: what is the link?
    Douglas A Drossman
    Am J Gastroenterol 99:358-60. 2004
  56. ncbi request reprint The "organification" of functional GI disorders: implications for research
    Douglas A Drossman
    Gastroenterology 124:6-7. 2003
  57. ncbi request reprint New developments in the diagnosis and treatment of irritable bowel syndrome
    George F Longstreth
    Department of Gastroenterology, Kaiser Permanente Medical Care Program, 4647 Zion Avenue, San Diego, CA 92120, USA
    Curr Gastroenterol Rep 4:427-34. 2002
    ..Various forms of psychological therapy and new serotonin-modulating agents seem especially promising. The placebo effect of the physician-patient relationship has important therapeutic benefit...
  58. ncbi request reprint Re: Groll et al.--Comparison of IBS-36 and IBS-QOL instruments
    Donald L Patrick
    Am J Gastroenterol 97:3204; author reply 3204-5. 2002
  59. ncbi request reprint Relationship of abuse history and other risk factors with obesity among female gastrointestinal patients
    Huanguang Jia
    Rehabilitation Outcomes Research Center, VA Medical Center, Gainesville, Florida 32608, USA
    Dig Dis Sci 49:872-7. 2004
    ..Physical abuse history and several demographic factors were significantly related to being overweight and obese in this clinical population...
  60. ncbi request reprint Treatment for bacterial overgrowth in the irritable bowel syndrome
    Douglas A Drossman
    Ann Intern Med 145:626-8. 2006
  61. ncbi request reprint Validation of the Japanese version of the Rome II modular questionnaire and irritable bowel syndrome severity index
    Masae Shinozaki
    Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Seiryo, Aoba, Sendai, Japan
    J Gastroenterol 41:491-4. 2006
    ..The aim of this study was to develop, validate, and confirm the reliability of the Japanese version of the Rome II modular questionnaire for IBS (RIIMQ-J) and the IBS severity index (IBSSI-J)...
  62. doi request reprint Development of abdominal pain and IBS following gynecological surgery: a prospective, controlled study
    Ami D Sperber
    Department of Gastroenterology, Soroka University Medical Center, and Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Gastroenterology 134:75-84. 2008
    ..The aim of this prospective, controlled study was to assess the incidence of pain or IBS in women undergoing elective gynecological surgery compared to non-surgical controls and to identify factors associated with their development...
  63. pmc Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome
    Ted J Kaptchuk
    Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
    BMJ 336:999-1003. 2008
    ..To assess the relative magnitude of these components...
  64. ncbi request reprint Diagnosing anxiety and depression among patients in referral GI practices: help or hindrance?
    Douglas A Drossman
    J Clin Gastroenterol 42:659-61. 2008
  65. ncbi request reprint A survey on patient educational needs in irritable bowel syndrome and attitudes toward participation in clinical research
    Albena D Halpert
    Boston University School of Medicine, Boston, MA 02118, USA
    J Clin Gastroenterol 40:37-43. 2006
    ..The educational needs of patients with irritable bowel syndrome (IBS) are poorly understood and rarely studied...
  66. ncbi request reprint Irritable bowel syndrome: toward an understanding of severity
    Anthony Lembo
    Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Clin Gastroenterol Hepatol 3:717-25. 2005
    ..However, studies have not been adequately designed to determine the relative values of these factors in IBS severity...
  67. ncbi request reprint Functional GI disorders: what's in a name?
    Douglas A Drossman
    Gastroenterology 128:1771-2. 2005
  68. ncbi request reprint Further validation of the IBS-QOL: female Mexican IBS patients have poorer quality of life than females from North Carolina
    Max Schmulson
    Laboratory of Liver, Pancreas and Motility HIPAM, Department of Experimental Medicine, Faculty of Medicine, Universidad Nacional Autonoma de Mexico UNAM, Mexico City, Mexico
    Dig Dis Sci 52:2950-5. 2007
    ..Using this instrument we found that female IBS patients who consulted a tertiary referral center in Mexico have lower HRQOL than those in North Carolina at least in factors such as Body Image and Health Worry...
  69. ncbi request reprint Functional chest pain of presumed esophageal origin
    Yehuda Ringel
    Arch Intern Med 162:365-6. 2002

Research Grants7

  1. MULTICENTER TRIAL OF FUNCTIONAL BOWEL DISORDERS
    Douglas Drossman; Fiscal Year: 2001
    ....