Daniel Dries

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension
    Daniel L Dries
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, University of Texas at Southwestern Medical Center, Dallas, USA
    Circulation 112:2403-10. 2005
  2. doi Simultaneous assessment of unprocessed ProBNP1-108 in addition to processed BNP32 improves identification of high-risk ambulatory patients with heart failure
    Daniel L Dries
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA PA 19104, USA
    Circ Heart Fail 3:220-7. 2010
  3. pmc Natriuretic peptides and the genomics of left-ventricular hypertrophy
    Daniel L Dries
    Penn Cardiovascular Institute and Cardiovascular Division, Heart Failure and Transplant Group, Heart Vascular Center, 3400 Civic Center Boulevard, Philadelphia, PA 19104 4283, USA
    Heart Fail Clin 6:55-64. 2010
  4. pmc Dysfunctional corin i555(p568) allele is associated with impaired brain natriuretic peptide processing and adverse outcomes in blacks with systolic heart failure: results from the Genetic Risk Assessment in Heart Failure substudy
    J Eduardo Rame
    Division of Cardiology, University of California San Francisco, San Francisco, California, USA
    Circ Heart Fail 2:541-8. 2009
  5. ncbi Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload
    J Eduardo Rame
    Division of Cardiology, University of California San Francisco, USA
    Hypertension 49:857-64. 2007
  6. pmc Genomics, transcriptional profiling, and heart failure
    Kenneth B Margulies
    Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Coll Cardiol 53:1752-9. 2009
  7. doi Ventilatory inefficiency reflects right ventricular dysfunction in systolic heart failure
    Amanda B Methvin
    Cardiovascular Division, Heart Failure Transplant Program, University of Pennsylvania School of Medicine, Perelman Center for Advanced Medicine, Heart and Vascular Center, 2 E Pavilion, Philadelphia, PA 19104, USA
    Chest 139:617-25. 2011
  8. ncbi Impact of body mass and body composition on circulating levels of natriuretic peptides: results from the Dallas Heart Study
    Sandeep R Das
    Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Circulation 112:2163-8. 2005
  9. ncbi Left ventricular hypertrophy is more prevalent in blacks than whites in the general population: the Dallas Heart Study
    Mark H Drazner
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Hypertension 46:124-9. 2005
  10. ncbi Efficacy of angiotensin-converting enzyme inhibition in reducing progression from asymptomatic left ventricular dysfunction to symptomatic heart failure in black and white patients
    Daniel L Dries
    Heart Failure Research Group, Cardiology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9034, USA
    J Am Coll Cardiol 40:311-7. 2002

Research Grants

Collaborators

Detail Information

Publications19

  1. ncbi Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension
    Daniel L Dries
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, University of Texas at Southwestern Medical Center, Dallas, USA
    Circulation 112:2403-10. 2005
    ..The natriuretic peptide system contributes to blood pressure regulation. Atrial and brain natriuretic peptides are cleaved into smaller biologically active molecules by corin, a transmembrane serine protease expressed in cardiomyocytes...
  2. doi Simultaneous assessment of unprocessed ProBNP1-108 in addition to processed BNP32 improves identification of high-risk ambulatory patients with heart failure
    Daniel L Dries
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA PA 19104, USA
    Circ Heart Fail 3:220-7. 2010
    ..We hypothesized that simultaneous assessment of proBNP(1-108) and active BNP32, as an index of natriuretic peptide processing efficiency, would improve risk stratification in patients with chronic systolic heart failure...
  3. pmc Natriuretic peptides and the genomics of left-ventricular hypertrophy
    Daniel L Dries
    Penn Cardiovascular Institute and Cardiovascular Division, Heart Failure and Transplant Group, Heart Vascular Center, 3400 Civic Center Boulevard, Philadelphia, PA 19104 4283, USA
    Heart Fail Clin 6:55-64. 2010
    ..It promises the opportunity to identify high-risk individuals for targeted intervention and may identify novel therapeutic targets for improved prevention and treatment strategies...
  4. pmc Dysfunctional corin i555(p568) allele is associated with impaired brain natriuretic peptide processing and adverse outcomes in blacks with systolic heart failure: results from the Genetic Risk Assessment in Heart Failure substudy
    J Eduardo Rame
    Division of Cardiology, University of California San Francisco, San Francisco, California, USA
    Circ Heart Fail 2:541-8. 2009
    ..We hypothesized that the corin I555(P568) allele would be associated with adverse outcomes and impaired BNP processing in blacks with systolic heart failure...
  5. ncbi Corin I555(P568) allele is associated with enhanced cardiac hypertrophic response to increased systemic afterload
    J Eduardo Rame
    Division of Cardiology, University of California San Francisco, USA
    Hypertension 49:857-64. 2007
    ..These data suggest that the corin I555(P568) allele represents a cardiac hypertrophy-sensitizing genetic locus in systemic hypertension...
  6. pmc Genomics, transcriptional profiling, and heart failure
    Kenneth B Margulies
    Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Am Coll Cardiol 53:1752-9. 2009
    ....
  7. doi Ventilatory inefficiency reflects right ventricular dysfunction in systolic heart failure
    Amanda B Methvin
    Cardiovascular Division, Heart Failure Transplant Program, University of Pennsylvania School of Medicine, Perelman Center for Advanced Medicine, Heart and Vascular Center, 2 E Pavilion, Philadelphia, PA 19104, USA
    Chest 139:617-25. 2011
    ..A direct link between VI and a specific cardiac abnormality has not been established...
  8. ncbi Impact of body mass and body composition on circulating levels of natriuretic peptides: results from the Dallas Heart Study
    Sandeep R Das
    Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Circulation 112:2163-8. 2005
    ....
  9. ncbi Left ventricular hypertrophy is more prevalent in blacks than whites in the general population: the Dallas Heart Study
    Mark H Drazner
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Hypertension 46:124-9. 2005
    ..The ethnic differences in left ventricular mass are independent of differences in body composition...
  10. ncbi Efficacy of angiotensin-converting enzyme inhibition in reducing progression from asymptomatic left ventricular dysfunction to symptomatic heart failure in black and white patients
    Daniel L Dries
    Heart Failure Research Group, Cardiology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9034, USA
    J Am Coll Cardiol 40:311-7. 2002
    ..This study was undertaken to determine whether enalapril had comparable efficacy in black and white patients with asymptomatic left ventricular dysfunction (ALVD) in preventing the development of symptomatic heart failure (HF)...
  11. doi Blacks and whites have a similar prevalence of reduced left ventricular ejection fraction in the general population: the Dallas Heart Study (DHS)
    David W Markham
    Donald W Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390 9047, USA
    Am Heart J 155:876-82. 2008
    ..Because of the higher prevalence of risk factors for heart failure in blacks, including hypertension, obesity, and LV hypertrophy, we hypothesized that LV dysfunction would also be more common in this ethnic group...
  12. ncbi Third heart sound and elevated jugular venous pressure as markers of the subsequent development of heart failure in patients with asymptomatic left ventricular dysfunction
    Mark H Drazner
    Heart Failure Research Unit, Donald W Reynolds Cardiovascular Clinical Research Center, Dallas, Texas 75390, USA
    Am J Med 114:431-7. 2003
    ..To determine the independent prognostic value of a third heart sound (S(3)) and elevated jugular venous pressure in patients with asymptomatic left ventricular dysfunction...
  13. ncbi Increased left ventricular mass is a risk factor for the development of a depressed left ventricular ejection fraction within five years: the Cardiovascular Health Study
    Mark H Drazner
    Heart Failure Research Unit, Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Am Coll Cardiol 43:2207-15. 2004
    ..Our aim in this study was to determine whether increased left ventricular mass (LVM) is a risk factor for the development of a reduced left ventricular ejection fraction (LVEF)...
  14. ncbi Comparison of impedance cardiography with invasive hemodynamic measurements in patients with heart failure secondary to ischemic or nonischemic cardiomyopathy
    Mark H Drazner
    Heart Failure Research Unit, Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, Department of Internal Medicine, University of Texas Southwest Medical Center, Dallas, Texas 75390 9034, USA
    Am J Cardiol 89:993-5. 2002
  15. ncbi Effects of diabetes mellitus and ischemic heart disease on the progression from asymptomatic left ventricular dysfunction to symptomatic heart failure: a retrospective analysis from the Studies of Left Ventricular Dysfunction (SOLVD) Prevention trial
    Sandeep R Das
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiology, University of Texas Southwestern Medical School, Dallas, Tex, USA
    Am Heart J 148:883-8. 2004
    ..Whether diabetes mellitus is a risk factor for the progression from asymptomatic left ventricular systolic dysfunction to symptomatic heart failure in patients with left ventricular dysfunction of an ischemic cause is not known...
  16. ncbi Beta-blocker therapy in patients with heart failure in the urban setting: moving beyond clinical trials
    Jerry D Estep
    Heart Failure Research Unit, Dallas, Tex, USA
    Am Heart J 148:958-63. 2004
    ..We wanted to identify patient characteristics that could guide primary care physicians in deciding whether they or a cardiologist should initiate BBL. A second objective was to determine the tolerability of BBL in clinical practice...
  17. pmc Corin variant associated with hypertension and cardiac hypertrophy exhibits impaired zymogen activation and natriuretic peptide processing activity
    Wei Wang
    Molecular Cardiology, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Circ Res 103:502-8. 2008
    ..Our data suggest that corin deficiency may be an important mechanism in hypertensive and heart diseases...
  18. ncbi Relevance of molecular forms of brain natriuretic peptide for natriuretic peptide research
    Daniel L Dries
    Hypertension 49:971-3. 2007
  19. ncbi Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction
    J Eduardo Rame
    Cardiovascular Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA
    Am J Cardiol 93:234-7. 2004
    ..Risk factors for this outcome included a history of coronary artery disease, pulmonary edema seen on a chest x-ray, or a subsequent myocardial infarction...

Research Grants6

  1. Genetic Determinants of Hypertension, LVH, and CHF
    Daniel Dries; Fiscal Year: 2006
    ..In addition we will analyze the association of these genotypes with prognosis in patients with advanced systolic heart failure. ..
  2. Genetic Determinants of Hypertensive Heart Disease in CRI
    Daniel Dries; Fiscal Year: 2009
    ....
  3. Genetic Determinants of Hypertensive Heart Disease in CRI
    Daniel L Dries; Fiscal Year: 2010
    ....