K J Doyle

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Neonatal middle ear effusion predicts chronic otitis media with effusion
    Karen Jo Doyle
    University of California Davis Medical Center, Sacramento, California, USA
    Otol Neurotol 25:318-22. 2004
  2. ncbi Intratympanic steroid treatment: a review
    Karen Jo Doyle
    Department of Otolaryngology Head and Neck Surgery, University of California Davis, Sacramento, California 95817, USA
    Otol Neurotol 25:1034-9. 2004
  3. ncbi Effects of difluoromethylornithine chemoprevention on audiometry thresholds and otoacoustic emissions
    K J Doyle
    Department of Otolaryngology Head and Neck Surgery, University of California Davis Medical Center, Sacramento, CA 95817, USA
    Arch Otolaryngol Head Neck Surg 127:553-8. 2001
  4. ncbi The otolaryngologist's role in management of hearing loss in infancy and childhood
    Karen Jo Doyle
    Department of Otolaryngology Head and Neck Surgery, University of California Davis, Sacramento, California 95817, USA
    Ment Retard Dev Disabil Res Rev 9:94-102. 2003
  5. ncbi Difluoromethylornithine-induced reversible hearing loss across a wide frequency range
    Mark C Smith
    University of California, Davis Medical Center, Sacramento, CA, USA
    Laryngoscope 114:1113-7. 2004
  6. ncbi Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1
    Rodney C Diaz
    Department of Otolaryngology Head and Neck Surgery, University of California Davis School of Medicine, 1515 Newton Court, Davis, CA 95618, USA
    J Assoc Res Otolaryngol 8:422-34. 2007
  7. ncbi Delayed, reversible hearing loss caused by difluoromethylornithine (DFMO)
    K J Doyle
    Department of Otolaryngology-Head and Neck Surgery, University of California-Davis, 2521 Stockton Blvd, Ste. 7200, Sacramento, CA 95817
    Laryngoscope 111:781-5. 2001
  8. ncbi Neonatal hearing screening with otoscopy, auditory brain stem response, and otoacoustic emissions
    K J Doyle
    Department of Otolaryngology Head and Neck Surgery, University of California, Irvine, USA
    Otolaryngol Head Neck Surg 116:597-603. 1997
  9. ncbi The case for early identification of hearing loss in children. Auditory system development, experimental auditory deprivation, and development of speech perception and hearing
    Y S Sininger
    Children s Auditory Research and Evaluation Center, University of California Davis Medical Center, USA
    Pediatr Clin North Am 46:1-14. 1999
  10. ncbi The gender gap in a surgical subspecialty: analysis of career and lifestyle factors
    Jennifer Rubin Grandis
    Eye and Ear Institute, Department of Otolaryngology, School of Medicine, University of Pittsburgh, PA 15213, USA
    Arch Otolaryngol Head Neck Surg 130:695-702. 2004

Detail Information

Publications11

  1. ncbi Neonatal middle ear effusion predicts chronic otitis media with effusion
    Karen Jo Doyle
    University of California Davis Medical Center, Sacramento, California, USA
    Otol Neurotol 25:318-22. 2004
    ..The hypothesis is that neonates with middle ear effusion persisting to 30 to 48 hours are more likely to develop chronic otitis media with effusion...
  2. ncbi Intratympanic steroid treatment: a review
    Karen Jo Doyle
    Department of Otolaryngology Head and Neck Surgery, University of California Davis, Sacramento, California 95817, USA
    Otol Neurotol 25:1034-9. 2004
    ..To review published literature regarding the use of intratympanic steroids in the treatment of Meniere's disease and sudden sensorineural hearing loss and to make recommendations regarding their use based on the literature review...
  3. ncbi Effects of difluoromethylornithine chemoprevention on audiometry thresholds and otoacoustic emissions
    K J Doyle
    Department of Otolaryngology Head and Neck Surgery, University of California Davis Medical Center, Sacramento, CA 95817, USA
    Arch Otolaryngol Head Neck Surg 127:553-8. 2001
    ..To determine the effects of long-term, low-dose difluoromethylornithine (DFMO) on audiometric thresholds and distortion product otoacoustic emission (DPOAE) levels in humans...
  4. ncbi The otolaryngologist's role in management of hearing loss in infancy and childhood
    Karen Jo Doyle
    Department of Otolaryngology Head and Neck Surgery, University of California Davis, Sacramento, California 95817, USA
    Ment Retard Dev Disabil Res Rev 9:94-102. 2003
    ..Finally, surgeries used by otolaryngologists to treat childhood hearing loss, their indications, and outcomes, are discussed...
  5. ncbi Difluoromethylornithine-induced reversible hearing loss across a wide frequency range
    Mark C Smith
    University of California, Davis Medical Center, Sacramento, CA, USA
    Laryngoscope 114:1113-7. 2004
    ..The objectives of this study are 1) to measure HL and recovery at several frequencies in neonatal gerbils after DFMO therapy at two different dosing regimens and 2) to identify any effects of DFMO on cochlear histology...
  6. ncbi Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1
    Rodney C Diaz
    Department of Otolaryngology Head and Neck Surgery, University of California Davis School of Medicine, 1515 Newton Court, Davis, CA 95618, USA
    J Assoc Res Otolaryngol 8:422-34. 2007
    ..These observations provide insight into the detailed mechanisms of EP generation, and results of combination-knockout experiments may have important implications in the future treatment of drug-induced and age-related hearing losses...
  7. ncbi Delayed, reversible hearing loss caused by difluoromethylornithine (DFMO)
    K J Doyle
    Department of Otolaryngology-Head and Neck Surgery, University of California-Davis, 2521 Stockton Blvd, Ste. 7200, Sacramento, CA 95817
    Laryngoscope 111:781-5. 2001
    ..Differences were statistically significant. CONCLUSIONS: DFMO causes mild to moderate HL in neonatal gerbils that recovers after discontinuation of the drug...
  8. ncbi Neonatal hearing screening with otoscopy, auditory brain stem response, and otoacoustic emissions
    K J Doyle
    Department of Otolaryngology Head and Neck Surgery, University of California, Irvine, USA
    Otolaryngol Head Neck Surg 116:597-603. 1997
    ..Prevalence of occluding external canal vernix and middle ear effusion as a function of increasing infant age were studied. Implications for newborn hearing screening are discussed...
  9. ncbi The case for early identification of hearing loss in children. Auditory system development, experimental auditory deprivation, and development of speech perception and hearing
    Y S Sininger
    Children s Auditory Research and Evaluation Center, University of California Davis Medical Center, USA
    Pediatr Clin North Am 46:1-14. 1999
    ..All evidence regarding neural development supports such early intervention for maximum development of communication ability and hearing in infants...
  10. ncbi The gender gap in a surgical subspecialty: analysis of career and lifestyle factors
    Jennifer Rubin Grandis
    Eye and Ear Institute, Department of Otolaryngology, School of Medicine, University of Pittsburgh, PA 15213, USA
    Arch Otolaryngol Head Neck Surg 130:695-702. 2004
    ..Although the percentage of women in surgical subspecialties is increasing, little is known about the experiences of these women compared with their male counterparts...
  11. ncbi Functional consequences of polyamine synthesis inhibition by L-alpha-difluoromethylornithine (DFMO): cellular mechanisms for DFMO-mediated ototoxicity
    Liping Nie
    Center for Neuroscience, Department of Otolaryngology, University of California, Davis 95616, USA
    J Biol Chem 280:15097-102. 2005
    ..1 confers the outflow of K(+) in the stria vascularis. We have proposed an alternative model. These findings should also enable the rational design of new pharmaceuticals devoid of the untoward effect of DFMO...