Julie Douglas

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Probability of detection of genotyping errors and mutations as inheritance inconsistencies in nuclear-family data
    Julie A Douglas
    Department of Human Genetics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109 0618, USA
    Am J Hum Genet 70:487-95. 2002
  2. pmc Mammographic breast density--evidence for genetic correlations with established breast cancer risk factors
    Julie A Douglas
    Department of Human Genetics, University of Michigan Medical School, Room 5912, Buhl Building, 1241 E Catherine Street, Ann Arbor, MI 48109 5618, USA
    Cancer Epidemiol Biomarkers Prev 17:3509-16. 2008
  3. pmc PedMine--a simulated annealing algorithm to identify maximally unrelated individuals in population isolates
    Julie A Douglas
    Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA
    Bioinformatics 24:1106-8. 2008
  4. pmc Common variation in the BRCA1 gene and prostate cancer risk
    Julie A Douglas
    Department of Human Genetics, University of Michigan, Room 5912, Buhl Building, Ann Arbor, MI 48109 0618, USA
    Cancer Epidemiol Biomarkers Prev 16:1510-6. 2007
  5. ncbi request reprint History and molecular genetics of Lynch syndrome in family G: a century later
    Julie A Douglas
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618, USA
    JAMA 294:2195-202. 2005
  6. ncbi request reprint Identifying susceptibility genes for prostate cancer--a family-based association study of polymorphisms in CYP17, CYP19, CYP11A1, and LH-beta
    Julie A Douglas
    Department of Human Genetics, University of Michigan, Room 5912, Buhl Building, Ann Arbor, MI 48109 0618, USA
    Cancer Epidemiol Biomarkers Prev 14:2035-9. 2005
  7. ncbi request reprint CDX2 polymorphisms, RNA expression, and risk of colorectal cancer
    Laura S Rozek
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 0638, USA
    Cancer Res 65:5488-92. 2005
  8. pmc Computerized image analysis: texture-field orientation method for pectoral muscle identification on MLO-view mammograms
    Chuan Zhou
    Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109 5842, USA
    Med Phys 37:2289-99. 2010
  9. ncbi request reprint Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109 0618, USA
    Prostate 67:1507-13. 2007
  10. pmc Extent and distribution of linkage disequilibrium in the Old Order Amish
    Cristopher V Van Hout
    Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, 48109 5618, USA
    Genet Epidemiol 34:146-50. 2010

Research Grants

  1. Mapping Genes for Mammographic Breast Density
    Julie Douglas; Fiscal Year: 2007
  2. Mapping Genes for Mammographic Breast Density
    Julie A Douglas; Fiscal Year: 2010

Detail Information

Publications22

  1. pmc Probability of detection of genotyping errors and mutations as inheritance inconsistencies in nuclear-family data
    Julie A Douglas
    Department of Human Genetics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109 0618, USA
    Am J Hum Genet 70:487-95. 2002
    ..Such early assessments are valuable in either the targeting of families for resampling or discontinued genotyping...
  2. pmc Mammographic breast density--evidence for genetic correlations with established breast cancer risk factors
    Julie A Douglas
    Department of Human Genetics, University of Michigan Medical School, Room 5912, Buhl Building, 1241 E Catherine Street, Ann Arbor, MI 48109 5618, USA
    Cancer Epidemiol Biomarkers Prev 17:3509-16. 2008
    ..This shared genetic architecture should be considered in future genetic studies of breast density...
  3. pmc PedMine--a simulated annealing algorithm to identify maximally unrelated individuals in population isolates
    Julie A Douglas
    Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA
    Bioinformatics 24:1106-8. 2008
    ..Given one or more pedigrees, our program automatically and rapidly extracts a fixed number of maximally unrelated individuals. AVAILABILITY: http://www.hg.med.umich.edu/labs/douglaslab/software.html (version 1.0.0)...
  4. pmc Common variation in the BRCA1 gene and prostate cancer risk
    Julie A Douglas
    Department of Human Genetics, University of Michigan, Room 5912, Buhl Building, Ann Arbor, MI 48109 0618, USA
    Cancer Epidemiol Biomarkers Prev 16:1510-6. 2007
    ..022). Thus, we have identified a common, nonsynonymous substitution in the BRCA1 gene that is associated with and linked to prostate cancer...
  5. ncbi request reprint History and molecular genetics of Lynch syndrome in family G: a century later
    Julie A Douglas
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618, USA
    JAMA 294:2195-202. 2005
    ..Described today as a Lynch syndrome family, family G was last documented in 1971, prior to the modern era of molecular diagnostics...
  6. ncbi request reprint Identifying susceptibility genes for prostate cancer--a family-based association study of polymorphisms in CYP17, CYP19, CYP11A1, and LH-beta
    Julie A Douglas
    Department of Human Genetics, University of Michigan, Room 5912, Buhl Building, Ann Arbor, MI 48109 0618, USA
    Cancer Epidemiol Biomarkers Prev 14:2035-9. 2005
    ....
  7. ncbi request reprint CDX2 polymorphisms, RNA expression, and risk of colorectal cancer
    Laura S Rozek
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 0638, USA
    Cancer Res 65:5488-92. 2005
    ....
  8. pmc Computerized image analysis: texture-field orientation method for pectoral muscle identification on MLO-view mammograms
    Chuan Zhou
    Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109 5842, USA
    Med Phys 37:2289-99. 2010
    ..To develop a new texture-field orientation (TFO) method that combines a priori knowledge, local and global information for the automated identification of pectoral muscle on mammograms...
  9. ncbi request reprint Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109 0618, USA
    Prostate 67:1507-13. 2007
    ..An initial study has also suggested that the risk of familial (but not sporadic) prostate cancer may be associated with germline variation in the AMACR gene...
  10. pmc Extent and distribution of linkage disequilibrium in the Old Order Amish
    Cristopher V Van Hout
    Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, 48109 5618, USA
    Genet Epidemiol 34:146-50. 2010
    ..Thus, in the context of the common variant-common disease hypothesis, genetic variants discovered in gene mapping studies in the OOA may generalize to other populations...
  11. pmc Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men
    Anna M Ray
    Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Prostate 69:956-60. 2009
    ..Here we examine the association between COI mutations and PCa in African American men...
  12. pmc Dynamic multiple thresholding breast boundary detection algorithm for mammograms
    Yi Ta Wu
    Department of Radiology, University of Michigan, Ann Arbor Michigan 48109, USA
    Med Phys 37:391-401. 2010
    ..In this study, the authors developed a new dynamic multiple thresholding based breast boundary (MTBB) detection method for digitized mammograms...
  13. doi request reprint Absence of CHEK2*1100delC mutation in families with hereditary breast cancer in North America
    Maria D Iniesta
    Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA
    Cancer Genet Cytogenet 202:136-40. 2010
    ....
  14. pmc Chromosome 17q12 variants contribute to risk of early-onset prostate cancer
    Albert M Levin
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 5618, USA
    Cancer Res 68:6492-5. 2008
    ..Thus, there likely exist one or more additional independent prostate cancer susceptibility loci in this region...
  15. ncbi request reprint Association between germline variation in the FHIT gene and prostate cancer in Caucasians and African Americans
    Albert M Levin
    Departments of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Cancer Epidemiol Biomarkers Prev 16:1294-7. 2007
    ....
  16. pmc Genetic influences on blood pressure response to the cold pressor test: results from the Heredity and Phenotype Intervention Heart Study
    Marie Hélène Roy-Gagnon
    Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA
    J Hypertens 26:729-36. 2008
    ..Additionally, to our knowledge, no study has examined the genetics of BP recovery from the CPT, including whether shared genetic factors influence both reactivity and recovery...
  17. pmc Analysis of RhoC expression and lymphovascular emboli in inflammatory vs non-inflammatory breast cancers in Egyptian patients
    An Chi Lo
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
    Breast 18:55-9. 2009
    ..Future studies should focus on relating epidemiologic factors to molecular features of IBC in this population...
  18. ncbi request reprint Description and genetic mapping of Polypodia: an X-linked dominant mouse mutant with ectopic caudal limbs and other malformations
    Jessica A Lehoczky
    Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109 0618, USA
    Mamm Genome 17:903-13. 2006
    ..We hypothesize that Ppd affects very early steps in the formation of caudal structures including limb and appendage number. The existence of noncaudal anomalies implies the involvement of Ppd in a broad array of cell fate decisions...
  19. ncbi request reprint Use of complementary and alternative medicine in men with family history of prostate cancer: a pilot study
    Jennifer L Beebe-Dimmer
    Department of Urology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0946, USA
    Urology 63:282-7. 2004
    ..To describe the use of complementary and alternative medicines (CAMs) among men with a family history of prostate cancer and to evaluate the relationship between selected sociodemographic and behavioral characteristics and the use of CAMs...
  20. pmc Molecular epidemiologic features of inflammatory breast cancer: a comparison between Egyptian and US patients
    An Chi Lo
    Department of Epidemiology, University of Michigan School of Public Health, 109 Observatory Street, Ann Arbor, MI 48109, USA
    Breast Cancer Res Treat 112:141-7. 2008
    ..A higher frequency of IBC and a more aggressive IBC phenotype was reported in Egypt than in the United States. This difference in disease frequency and presentation might be related to molecular epidemiologic factors...
  21. pmc Chromosome 8q24 markers: risk of early-onset and familial prostate cancer
    Jennifer L Beebe-Dimmer
    Karmanos Cancer Institute and Wayne State University, Detroit, MI, USA
    Int J Cancer 122:2876-9. 2008
    ..In addition, our results suggest that the increased risk associated with these SNPs is approximately doubled in individuals predisposed to develop early onset or clinically aggressive disease...
  22. ncbi request reprint A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14
    Kaisa Silander
    Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA
    Diabetes 53:821-9. 2004
    ....

Research Grants4

  1. Mapping Genes for Mammographic Breast Density
    Julie Douglas; Fiscal Year: 2007
    ....
  2. Mapping Genes for Mammographic Breast Density
    Julie A Douglas; Fiscal Year: 2010
    ....