Research Topics
Species | Julie DouglasSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Probability of detection of genotyping errors and mutations as inheritance inconsistencies in nuclear-family dataJulie A Douglas
Department of Human Genetics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109 0618, USA
Am J Hum Genet 70:487-95. 2002..Such early assessments are valuable in either the targeting of families for resampling or discontinued genotyping...- Mammographic breast density--evidence for genetic correlations with established breast cancer risk factorsJulie A Douglas
Department of Human Genetics, University of Michigan Medical School, Room 5912, Buhl Building, 1241 E Catherine Street, Ann Arbor, MI 48109 5618, USA
Cancer Epidemiol Biomarkers Prev 17:3509-16. 2008..This shared genetic architecture should be considered in future genetic studies of breast density... - PedMine--a simulated annealing algorithm to identify maximally unrelated individuals in population isolatesJulie A Douglas
Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA
Bioinformatics 24:1106-8. 2008..Given one or more pedigrees, our program automatically and rapidly extracts a fixed number of maximally unrelated individuals. AVAILABILITY: http://www.hg.med.umich.edu/labs/douglaslab/software.html (version 1.0.0)... - Common variation in the BRCA1 gene and prostate cancer riskJulie A Douglas
Department of Human Genetics, University of Michigan, Room 5912, Buhl Building, Ann Arbor, MI 48109 0618, USA
Cancer Epidemiol Biomarkers Prev 16:1510-6. 2007..022). Thus, we have identified a common, nonsynonymous substitution in the BRCA1 gene that is associated with and linked to prostate cancer... 
History and molecular genetics of Lynch syndrome in family G: a century laterJulie A Douglas
Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109 0618, USA
JAMA 294:2195-202. 2005..Described today as a Lynch syndrome family, family G was last documented in 1971, prior to the modern era of molecular diagnostics...- Identifying susceptibility genes for prostate cancer--a family-based association study of polymorphisms in CYP17, CYP19, CYP11A1, and LH-betaJulie A Douglas
Department of Human Genetics, University of Michigan, Room 5912, Buhl Building, Ann Arbor, MI 48109 0618, USA
Cancer Epidemiol Biomarkers Prev 14:2035-9. 2005.... - CDX2 polymorphisms, RNA expression, and risk of colorectal cancerLaura S Rozek
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 0638, USA
Cancer Res 65:5488-92. 2005.... - Computerized image analysis: texture-field orientation method for pectoral muscle identification on MLO-view mammogramsChuan Zhou
Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109 5842, USA
Med Phys 37:2289-99. 2010..To develop a new texture-field orientation (TFO) method that combines a priori knowledge, local and global information for the automated identification of pectoral muscle on mammograms... - Sequence variation in alpha-methylacyl-CoA racemase and risk of early-onset and familial prostate cancerAlbert M Levin
Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109 0618, USA
Prostate 67:1507-13. 2007..An initial study has also suggested that the risk of familial (but not sporadic) prostate cancer may be associated with germline variation in the AMACR gene... - Extent and distribution of linkage disequilibrium in the Old Order AmishCristopher V Van Hout
Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor, 48109 5618, USA
Genet Epidemiol 34:146-50. 2010..Thus, in the context of the common variant-common disease hypothesis, genetic variants discovered in gene mapping studies in the OOA may generalize to other populations... - Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American menAnna M Ray
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
Prostate 69:956-60. 2009..Here we examine the association between COI mutations and PCa in African American men... - Dynamic multiple thresholding breast boundary detection algorithm for mammogramsYi Ta Wu
Department of Radiology, University of Michigan, Ann Arbor Michigan 48109, USA
Med Phys 37:391-401. 2010..In this study, the authors developed a new dynamic multiple thresholding based breast boundary (MTBB) detection method for digitized mammograms... 
Absence of CHEK2*1100delC mutation in families with hereditary breast cancer in North AmericaMaria D Iniesta
Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA
Cancer Genet Cytogenet 202:136-40. 2010....- Chromosome 17q12 variants contribute to risk of early-onset prostate cancerAlbert M Levin
Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 5618, USA
Cancer Res 68:6492-5. 2008..Thus, there likely exist one or more additional independent prostate cancer susceptibility loci in this region... - Association between germline variation in the FHIT gene and prostate cancer in Caucasians and African AmericansAlbert M Levin
Departments of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA
Cancer Epidemiol Biomarkers Prev 16:1294-7. 2007.... - Genetic influences on blood pressure response to the cold pressor test: results from the Heredity and Phenotype Intervention Heart StudyMarie Hélène Roy-Gagnon
Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA
J Hypertens 26:729-36. 2008..Additionally, to our knowledge, no study has examined the genetics of BP recovery from the CPT, including whether shared genetic factors influence both reactivity and recovery... - Analysis of RhoC expression and lymphovascular emboli in inflammatory vs non-inflammatory breast cancers in Egyptian patientsAn Chi Lo
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
Breast 18:55-9. 2009..Future studies should focus on relating epidemiologic factors to molecular features of IBC in this population... - Description and genetic mapping of Polypodia: an X-linked dominant mouse mutant with ectopic caudal limbs and other malformationsJessica A Lehoczky
Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109-0618, USA
Mamm Genome 17:903-13. 2006..We hypothesize that Ppd affects very early steps in the formation of caudal structures including limb and appendage number. The existence of noncaudal anomalies implies the involvement of Ppd in a broad array of cell fate decisions... - Use of complementary and alternative medicine in men with family history of prostate cancer: a pilot studyJennifer L Beebe-Dimmer
Department of Urology, University of Michigan Medical School, Ann Arbor, Michigan 48109-0946, USA
Urology 63:282-7. 2004..The results of this study and others provide some insight into the determinants of potentially beneficial health behaviors in high-risk individuals... - Molecular epidemiologic features of inflammatory breast cancer: a comparison between Egyptian and US patientsAn Chi Lo
Department of Epidemiology, University of Michigan School of Public Health, 109 Observatory Street, Ann Arbor, MI 48109, USA
Breast Cancer Res Treat 112:141-7. 2008..A higher frequency of IBC and a more aggressive IBC phenotype was reported in Egypt than in the United States. This difference in disease frequency and presentation might be related to molecular epidemiologic factors... - Chromosome 8q24 markers: risk of early-onset and familial prostate cancerJennifer L Beebe-Dimmer
Karmanos Cancer Institute and Wayne State University, Detroit, MI, USA
Int J Cancer 122:2876-9. 2008..In addition, our results suggest that the increased risk associated with these SNPs is approximately doubled in individuals predisposed to develop early onset or clinically aggressive disease... - A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14Kaisa Silander
Genome Technology Branch, National Human Genome Research Institute, Bethesda, Maryland, USA
Diabetes 53:821-9. 2004....
Research Grants
- Mapping Genes for Mammographic Breast DensityJulie Douglas; Fiscal Year: 2007....
- Mapping Genes for Mammographic Breast DensityJulie A Douglas; Fiscal Year: 2010....