R I Dorsky

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Control of neural crest cell fate by the Wnt signalling pathway
    R I Dorsky
    Howard Hughes Medical Institute, Department of Pharmacology, University of Washington School of Medicine, Seattle 98195, USA
    Nature 396:370-3. 1998
  2. ncbi request reprint Maternal and embryonic expression of zebrafish lef1
    R I Dorsky
    HHMI and Department of Pharmacology, University of Washington, Seattle, WA 98195, USA
    Mech Dev 86:147-50. 1999
  3. pmc Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway
    R I Dorsky
    Howard Hughes Medical Institute and Department of Pharmacology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Genes Dev 14:158-62. 2000
  4. ncbi request reprint Environmental signals and cell fate specification in premigratory neural crest
    R I Dorsky
    Howard Hughes Medical Institute and Department of Pharmacology, University of Washington, Seattle, WA, USA
    Bioessays 22:708-16. 2000

Detail Information

Publications4

  1. ncbi request reprint Control of neural crest cell fate by the Wnt signalling pathway
    R I Dorsky
    Howard Hughes Medical Institute, Department of Pharmacology, University of Washington School of Medicine, Seattle 98195, USA
    Nature 396:370-3. 1998
    ..We conclude that endogenous Wnt signalling normally promotes pigment-cell formation by medial crest cells and thereby contributes to the diversity of neural crest cell fates...
  2. ncbi request reprint Maternal and embryonic expression of zebrafish lef1
    R I Dorsky
    HHMI and Department of Pharmacology, University of Washington, Seattle, WA 98195, USA
    Mech Dev 86:147-50. 1999
    ..In addition, we cloned two tcf3 genes and a homolog of tcf4, neither of which were strongly expressed in premigratory neural crest...
  3. pmc Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway
    R I Dorsky
    Howard Hughes Medical Institute and Department of Pharmacology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Genes Dev 14:158-62. 2000
    ..Mutation of Tcf/Lef sites abolishes Lef1 binding and reporter function in vivo. Wnt signaling therefore directly activates nacre, which in turn leads to pigment cell differentiation...
  4. ncbi request reprint Environmental signals and cell fate specification in premigratory neural crest
    R I Dorsky
    Howard Hughes Medical Institute and Department of Pharmacology, University of Washington, Seattle, WA, USA
    Bioessays 22:708-16. 2000
    ..This system may therefore provide a good model for integration of multiple signaling pathways during embryonic cell fate specification...