R I Dorsky
Affiliation: University of Washington
- Control of neural crest cell fate by the Wnt signalling pathwayR I Dorsky
Howard Hughes Medical Institute, Department of Pharmacology, University of Washington School of Medicine, Seattle 98195, USA
Nature 396:370-3. 1998..We conclude that endogenous Wnt signalling normally promotes pigment-cell formation by medial crest cells and thereby contributes to the diversity of neural crest cell fates...
- Maternal and embryonic expression of zebrafish lef1R I Dorsky
HHMI and Department of Pharmacology, University of Washington, Seattle, WA 98195, USA
Mech Dev 86:147-50. 1999..In addition, we cloned two tcf3 genes and a homolog of tcf4, neither of which were strongly expressed in premigratory neural crest...
- Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathwayR I Dorsky
Howard Hughes Medical Institute and Department of Pharmacology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Genes Dev 14:158-62. 2000..Mutation of Tcf/Lef sites abolishes Lef1 binding and reporter function in vivo. Wnt signaling therefore directly activates nacre, which in turn leads to pigment cell differentiation...
- Environmental signals and cell fate specification in premigratory neural crestR I Dorsky
Howard Hughes Medical Institute and Department of Pharmacology, University of Washington, Seattle, WA, USA
Bioessays 22:708-16. 2000..This system may therefore provide a good model for integration of multiple signaling pathways during embryonic cell fate specification...