Hans Dooms

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Revisiting the role of IL-2 in autoimmunity
    Hans Dooms
    Department of Pathology, University of California, San Francisco, CA 94143 0511, USA
    Eur J Immunol 40:1538-40. 2010
  2. ncbi Targeting T cell-specific costimulators and growth factors in a model of autoimmune hemolytic anemia
    Katrina K Hoyer
    Department of Pathology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    J Immunol 179:2844-50. 2007
  3. ncbi Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells
    Hans Dooms
    Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA
    J Exp Med 204:547-57. 2007
  4. ncbi IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells
    Cristina Penaranda
    Diabetes Center, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 109:12668-73. 2012
  5. ncbi Interleukin-2 in the development and control of inflammatory disease
    Katrina K Hoyer
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143, USA
    Immunol Rev 226:19-28. 2008
  6. ncbi Control of CD4+ T-cell memory by cytokines and costimulators
    Hans Dooms
    Department of Pathology, University of California-San Francisco, San Francisco, CA 94143-0511, USA
    Immunol Rev 211:23-38. 2006
  7. ncbi Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells
    Luke Barron
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143 0506, USA
    J Immunol 185:6426-30. 2010
  8. ncbi Opposing functions of IL-2 and IL-7 in the regulation of immune responses
    Shoshana D Katzman
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143 0511, USA
    Cytokine 56:116-21. 2011
  9. ncbi IL-2 induces a competitive survival advantage in T lymphocytes
    Hans Dooms
    Department of Pathology, University of California San Francisco School of Medicine, San Francisco, CA 94143, USA
    J Immunol 172:5973-9. 2004

Collaborators

Detail Information

Publications9

  1. ncbi Revisiting the role of IL-2 in autoimmunity
    Hans Dooms
    Department of Pathology, University of California, San Francisco, CA 94143 0511, USA
    Eur J Immunol 40:1538-40. 2010
    ..This commentary examines the current findings in relation to what we already know about IL-2 complexes...
  2. ncbi Targeting T cell-specific costimulators and growth factors in a model of autoimmune hemolytic anemia
    Katrina K Hoyer
    Department of Pathology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    J Immunol 179:2844-50. 2007
    ..Together, these data indicate that specific costimulatory and cytokine signals are critical for the spontaneous autoantibody-mediated disease that develops in IL-2-deficient mice...
  3. ncbi Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells
    Hans Dooms
    Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA
    J Exp Med 204:547-57. 2007
    ..These results identify IL-2 as a factor regulating IL-7Ralpha expression and, consequently, memory T cell homeostasis in vivo...
  4. ncbi IL-7 receptor blockade reverses autoimmune diabetes by promoting inhibition of effector/memory T cells
    Cristina Penaranda
    Diabetes Center, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 109:12668-73. 2012
    ....
  5. ncbi Interleukin-2 in the development and control of inflammatory disease
    Katrina K Hoyer
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143, USA
    Immunol Rev 226:19-28. 2008
    ..Thus, in its dual and contrasting functions, IL-2 contributes to both the induction and the termination of inflammatory immune responses...
  6. ncbi Control of CD4+ T-cell memory by cytokines and costimulators
    Hans Dooms
    Department of Pathology, University of California-San Francisco, San Francisco, CA 94143-0511, USA
    Immunol Rev 211:23-38. 2006
    ..Studies exploring the therapeutic potential of these insights are also discussed...
  7. ncbi Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells
    Luke Barron
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143 0506, USA
    J Immunol 185:6426-30. 2010
    ....
  8. ncbi Opposing functions of IL-2 and IL-7 in the regulation of immune responses
    Shoshana D Katzman
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143 0511, USA
    Cytokine 56:116-21. 2011
    ..Here we discuss the opposing functions of two members of the common receptor gamma chain (γc) cytokines, IL-2 and IL-7 in the generation and regulation of immune responses in vivo...
  9. ncbi IL-2 induces a competitive survival advantage in T lymphocytes
    Hans Dooms
    Department of Pathology, University of California San Francisco School of Medicine, San Francisco, CA 94143, USA
    J Immunol 172:5973-9. 2004
    ..Therefore, IL-2 enhances competitiveness for survival in CD4(+) T cells, thereby facilitating the development of a memory population...