M A Dooley

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi request reprint Review of ACR renal criteria in systemic lupus erythematosus
    M A Dooley
    Department of Medicine, Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA
    Lupus 13:857-60. 2004
  2. doi request reprint Effect of belimumab treatment on renal outcomes: results from the phase 3 belimumab clinical trials in patients with SLE
    M A Dooley
    University of North Carolina at Chapel Hill, NC 27599 7280, USA
    Lupus 22:63-72. 2013
  3. doi request reprint Therapy Insight: preserving fertility in cyclophosphamide-treated patients with rheumatic disease
    Mary Anne Dooley
    Division of Rheumatology and Immunology, University of North Carolina, 3330 Thurston Building, CB 7280, Chapel Hill, NC 27599 7280, USA
    Nat Clin Pract Rheumatol 4:250-7. 2008
  4. ncbi request reprint Human clinical trials in lupus nephritis
    Mary Anne Dooley
    Department of Medicine, Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Semin Nephrol 27:115-27. 2007
  5. ncbi request reprint Mycophenylate mofetil: what role in the treatment of lupus?
    M A Dooley
    Department of Medicine, Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, School of Medicine, USA
    Lupus 15:179-82. 2006
  6. ncbi request reprint Environmental epidemiology and risk factors for autoimmune disease
    M A Dooley
    Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, 27599, USA
    Curr Opin Rheumatol 15:99-103. 2003
  7. ncbi request reprint Silica exposure in anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and lupus nephritis
    S L Hogan
    Department of Medicine, The University of North Carolina at Chapel Hill, 27599-7155, USA
    J Am Soc Nephrol 12:134-42. 2001
  8. ncbi request reprint Osteoporosis prevention in premenopausal women: using a stage model approach to examine the predictors of behavior
    S J Blalock
    Thurston Arthritis Research Center, University of North Carolina at Chapel Hill 27599 7330, USA
    Health Psychol 15:84-93. 1996
  9. pmc Pharmacokinetics of mycophenolic acid in patients with lupus nephritis
    Melanie S Joy
    University of North Carolina Kidney Center, Chapel Hill, North Carolina 27599 7155, USA
    Pharmacotherapy 29:7-16. 2009
  10. ncbi request reprint Newer therapeutic approaches for systemic lupus erythematosus: immunosuppressive agents
    Mary Anne Dooley
    Rheum Dis Clin North Am 32:91-102, ix. 2006

Detail Information

Publications37

  1. ncbi request reprint Review of ACR renal criteria in systemic lupus erythematosus
    M A Dooley
    Department of Medicine, Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA
    Lupus 13:857-60. 2004
    ..Decline in renal function is not a reliable criterion given the numerous medications, comorbidities and other clinical circumstances which may result in this feature...
  2. doi request reprint Effect of belimumab treatment on renal outcomes: results from the phase 3 belimumab clinical trials in patients with SLE
    M A Dooley
    University of North Carolina at Chapel Hill, NC 27599 7280, USA
    Lupus 22:63-72. 2013
    ..The results suggest that belimumab may offer renal benefit in patients with SLE. Further study is warranted in patients with severe active lupus nephritis...
  3. doi request reprint Therapy Insight: preserving fertility in cyclophosphamide-treated patients with rheumatic disease
    Mary Anne Dooley
    Division of Rheumatology and Immunology, University of North Carolina, 3330 Thurston Building, CB 7280, Chapel Hill, NC 27599 7280, USA
    Nat Clin Pract Rheumatol 4:250-7. 2008
    ....
  4. ncbi request reprint Human clinical trials in lupus nephritis
    Mary Anne Dooley
    Department of Medicine, Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Semin Nephrol 27:115-27. 2007
    ..As long-term outcomes in lupus nephritis improve, the toxicity of therapy and risk of relapse become increasingly important determinants of the choice of therapeutic agents...
  5. ncbi request reprint Mycophenylate mofetil: what role in the treatment of lupus?
    M A Dooley
    Department of Medicine, Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, School of Medicine, USA
    Lupus 15:179-82. 2006
    ..As long-term outcomes in lupus improve, the toxicity of therapy and risk of relapse become increasingly important determinants of choice of therapeutic agents...
  6. ncbi request reprint Environmental epidemiology and risk factors for autoimmune disease
    M A Dooley
    Division of Rheumatology and Immunology, University of North Carolina at Chapel Hill, 27599, USA
    Curr Opin Rheumatol 15:99-103. 2003
    ....
  7. ncbi request reprint Silica exposure in anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and lupus nephritis
    S L Hogan
    Department of Medicine, The University of North Carolina at Chapel Hill, 27599-7155, USA
    J Am Soc Nephrol 12:134-42. 2001
    ..001; 95% confidence interval, <0.01 to >100; P = 0.993). Activities and environments known to cause high levels of exposure to silica dust were associated with ANCA-SVV but not with SLE nephritis...
  8. ncbi request reprint Osteoporosis prevention in premenopausal women: using a stage model approach to examine the predictors of behavior
    S J Blalock
    Thurston Arthritis Research Center, University of North Carolina at Chapel Hill 27599 7330, USA
    Health Psychol 15:84-93. 1996
    ....
  9. pmc Pharmacokinetics of mycophenolic acid in patients with lupus nephritis
    Melanie S Joy
    University of North Carolina Kidney Center, Chapel Hill, North Carolina 27599 7155, USA
    Pharmacotherapy 29:7-16. 2009
    ....
  10. ncbi request reprint Newer therapeutic approaches for systemic lupus erythematosus: immunosuppressive agents
    Mary Anne Dooley
    Rheum Dis Clin North Am 32:91-102, ix. 2006
    ..Some of these agents have multiple immunomodulatory effects, whereas others interfere with a specific immunologic process in one of the pathogenetic pathways of SLE activity...
  11. ncbi request reprint Patient knowledge, beliefs, and behavior concerning the prevention and treatment of glucocorticoid-induced osteoporosis
    Susan J Blalock
    University of North Carolina at Chapel Hill, 27599, USA
    Arthritis Rheum 53:732-9. 2005
    ..e., calcium intake, vitamin D intake, and bone mineral density [BMD] testing) recommended for patients receiving glucocorticoid therapy...
  12. pmc Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis
    Melanie S Joy
    School of Medicine, UNC Kidney Center, University of North Carolina, Chapel Hill, NC, USA
    Eur J Clin Pharmacol 66:1119-30. 2010
    ..The role of pharmacogenomics, clinical and demographic parameters in pharmacokinetic predictions was evaluated in patients receiving mycophenolic acid (MPA)...
  13. ncbi request reprint Renal transplantation in children with lupus nephritis
    Debbie S Gipson
    Divisions of Nephrology and Hypertension and Rheumatology, University of North Carolina Chapel Hill, NC, USA
    Am J Kidney Dis 41:455-63. 2003
    ..This study was conducted to determine renal allograft and patient survival for children with lupus nephritis compared with pediatric allograft recipients with other causes of end-stage renal disease...
  14. pmc Predictors of relapse and end stage kidney disease in proliferative lupus nephritis: focus on children, adolescents, and young adults
    Keisha L Gibson
    Division of Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7155, USA
    Clin J Am Soc Nephrol 4:1962-7. 2009
    ..Patterns and predictors of disease progression in a southeastern U.S. pediatric cohort with severe lupus nephritis are presented...
  15. ncbi request reprint Similar CD19 dysregulation in two autoantibody-associated autoimmune diseases suggests a shared mechanism of B-cell tolerance loss
    Donna A Culton
    Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    J Clin Immunol 27:53-68. 2007
    ..These findings have implications for autoreactive B-cell activation and suggest a shared mechanism of B-cell tolerance loss in these two diseases...
  16. doi request reprint Gonadal failure with cyclophosphamide therapy for lupus nephritis: advances in fertility preservation
    Jennifer Mersereau
    Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of North Carolina at Chapel Hill, CB 7570, 4001 Old Clinic Building, Chapel Hill, NC 27599 7570, USA
    Rheum Dis Clin North Am 36:99-108, viii. 2010
    ..This article reviews cyclophosphamide use, its effect on gonadal function, and protection of gonadal reserve during therapy. Egg, embryo, or gonadal tissue cryopreservation and alternative therapeutic strategies are considered...
  17. ncbi request reprint Leukocyte gene expression signatures in antineutrophil cytoplasmic autoantibody and lupus glomerulonephritis
    D A Alcorta
    CB 7155, Division of Nephrology and Hypertension, Department of Medicine, UNC Kidney Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Kidney Int 72:853-64. 2007
    ..Monitoring changes in the expression of specific genes may be a tool to help quantify disease activity during treatment...
  18. ncbi request reprint Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism
    Christine G Parks
    National Institute of Environmental Health Sciences, Durham, NC, USA
    Hum Immunol 65:622-31. 2004
    ..0, p < 0.00001) for the combined "HLA-DR3, TNF-alpha -308A, IL-1alpha -889C/C" genotype. These findings provide evidence of cytokine gene epistasis in SLE susceptibility...
  19. doi request reprint Total serum IgE levels in systemic lupus erythematosus and associations with childhood onset allergies
    C G Parks
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Durham, NC 27599, USA
    Lupus 19:1614-22. 2010
    ..Future studies may want to explore potentially shared risk factors for development of allergy, atopy, and SLE...
  20. pmc Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosus
    Henda Bouali
    Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Rheumatol 34:2028-34. 2007
    ..We hypothesized that the G-463A MPO SNP is a risk factor for developing lupus nephritis (LN) due to its potential influence on the inflammatory response...
  21. pmc A novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLE
    Matilda W Nicholas
    Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Clin Immunol 126:189-201. 2008
    ..Thus, CD19(hi) B cells are precursors to anti-self PCs, and identify an SLE patient subset likely to experience poor clinical outcomes...
  22. ncbi request reprint Effects of an osteoporosis prevention program incorporating tailored educational materials
    Susan J Blalock
    School of Pharmacy and Health Sciences, University of the Pacific, Stockton, California 95211, USA
    Am J Health Promot 16:146-56. 2002
    ..To evaluate the effects of two interventions on calcium intake and exercise and assess whether intervention effects varied as a function of participants' stage of change...
  23. ncbi request reprint Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis
    Ellen M Ginzler
    Division of Rheumatology, State University of New York Downstate Medical Center, Brooklyn, NY 11203, USA
    N Engl J Med 353:2219-28. 2005
    ..Since anecdotal series and small, prospective, controlled trials suggest that mycophenolate mofetil may be effective for treating lupus nephritis, larger trials are desirable...
  24. doi request reprint Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal response
    Michelle Petri
    Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Arthritis Rheum 58:1789-95. 2008
    ..To assess the degree to which physicians agree with each other and with ratings obtained with 3 existing responder indices, in rating the response to treatment of lupus nephritis...
  25. doi request reprint Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response index
    Michelle Petri
    Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Arthritis Rheum 58:1784-8. 2008
    ..To develop a measure of renal activity in systemic lupus erythematosus and use it to develop a renal response index...
  26. ncbi request reprint Glutathione S-transferase M null homozygosity and risk of systemic lupus erythematosus associated with sun exposure: a possible gene-environment interaction for autoimmunity
    Patricia A Fraser
    Center for Blood Research, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Rheumatol 30:276-82. 2003
    ..We hypothesized that risk of SLE associated with occupational sun exposure is modulated by GSTM1, GSTT1, and GSTP1 genotypes...
  27. ncbi request reprint Sociodemographic associations with early disease damage in patients with systemic lupus erythematosus
    Glinda S Cooper
    US Environmental Protection Agency, Washington, DC 20460, USA
    Arthritis Rheum 57:993-9. 2007
    ..To examine the extent of organ damage among recently diagnosed patients with systemic lupus erythematosus (SLE), and to assess the association between sociodemographic variables and total damage and organ-specific damage scores...
  28. ncbi request reprint N-acetyl transferase genotypes in relation to risk of developing systemic lupus erythematosus
    Glinda S Cooper
    Epidemiology Branch, National Institute of Environmental Health Sciences, Durham, North Carolina 27709, USA
    J Rheumatol 31:76-80. 2004
    ..To examine the association between N-acetyl transferase (NAT) genotype (NAT1 and NAT2) and risk of developing systemic lupus erythematosus (SLE)...
  29. ncbi request reprint Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus
    Glenn Douglas
    Medical Research Service, Ralph H Johnson Veterans Administration Medical Center and Medical University of South Carolina, Charleston, South Carolina, USA
    J Rheumatol 31:1756-62. 2004
    ..We hypothesized that polymorphisms in the genes coding for ACE and eNOS may influence the development and/or progression of systemic lupus erythematosus (SLE) and lupus nephritis given their linkage with other renal diseases...
  30. ncbi request reprint Occupational risk factors for the development of systemic lupus erythematosus
    Glinda S Cooper
    Epidemiology Branch, National Institute of Environmental Health Sciences, Durham, North Carolina 27709, USA
    J Rheumatol 31:1928-33. 2004
    ..We examined the association between the risk of SLE and occupational exposures (mercury, solvents, and pesticides), specific jobs (ever worked in teaching, healthcare, and cosmetology), and working night or rotating shifts...
  31. ncbi request reprint Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype
    Christine G Parks
    National Institute of Environmental Health Sciences, Durham, North Carolina, USA
    Arthritis Rheum 52:1148-59. 2005
    ..This study examined the seroprevalence of EBV in a population-based study of SLE patients from the southeastern United States, and potential interactions with CTLA-4 polymorphisms were assessed...
  32. ncbi request reprint The effect of combined estrogen and progesterone hormone replacement therapy on disease activity in systemic lupus erythematosus: a randomized trial
    Jill P Buyon
    Hospital for Joint Diseases, New York University School of Medicine, New York, New York, USA
    Ann Intern Med 142:953-62. 2005
    ..There is concern that exogenous female hormones may worsen disease activity in women with systemic lupus erythematosus (SLE)...
  33. ncbi request reprint Risk factors for development of systemic lupus erythematosus: allergies, infections, and family history
    Glinda S Cooper
    Epidemiology Branch A3 05, National Institute of Environmental Health Sciences, PO Box 12233, Durham, NC 27709, USA
    J Clin Epidemiol 55:982-9. 2002
    ..3, 95% CI 1.2-8.6). Further research is needed to clarify whether medication allergies and specific infectious agents are involved in the etiology of SLE. Published by Elsevier Science Inc...
  34. ncbi request reprint Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States
    Christine G Parks
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, North Carolina 27709, USA
    Arthritis Rheum 46:1840-50. 2002
    ..We undertook this population-based study to examine the association between occupational silica exposure and SLE in the southeastern US...
  35. ncbi request reprint Epidemiology and health services: year in review
    Mary Anne Dooley
    Curr Opin Rheumatol 19:118-21. 2007
    ..The field has grown to include many subfields recognizing the contributions of multiple factors to disease susceptibility...
  36. ncbi request reprint Hormonal and reproductive risk factors for development of systemic lupus erythematosus: results of a population-based, case-control study
    Glinda S Cooper
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, North Carolina 27709, USA
    Arthritis Rheum 46:1830-9. 2002
    ..In humans, 85% of lupus patients are women, which also suggests the importance of hormonal factors in disease pathogenesis. The purpose of this study was to examine hormonal and reproductive risk factors for lupus among women...
  37. ncbi request reprint Combined oral contraceptives in women with systemic lupus erythematosus
    Michelle Petri
    Johns Hopkins University School of Medicine, Baltimore, USA
    N Engl J Med 353:2550-8. 2005
    ..In this double-blind, randomized, noninferiority trial, we prospectively evaluated the effect of oral contraceptives on lupus activity in premenopausal women with systemic lupus erythematosus...