EDWARD DOMINO

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Changes in craving for a cigarette and arterial nicotine plasma concentrations in abstinent smokers
    Sally K Guthrie
    College of Pharmacy, University of Michigan, Ann Arbor 48109 1065, USA
    Prog Neuropsychopharmacol Biol Psychiatry 28:617-23. 2004
  2. pmc Denicotinized versus average nicotine tobacco cigarette smoking differentially releases striatal dopamine
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 5632, USA
    Nicotine Tob Res 15:11-21. 2013
  3. pmc Phencyclidine/schizophrenia: one view toward the past, the other to the future
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 5632, USA
    Schizophr Bull 38:914-9. 2012
  4. doi request reprint Tobacco smoking produces greater striatal dopamine release in G-allele carriers with mu opioid receptor A118G polymorphism
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 5632, USA
    Prog Neuropsychopharmacol Biol Psychiatry 38:236-40. 2012
  5. ncbi request reprint Effects of nicotine on regional cerebral glucose metabolism in awake resting tobacco smokers
    E F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Neuroscience 101:277-82. 2000
  6. pmc Tobacco smoking and MRI/MRS brain abnormalities compared to nonsmokers
    E F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, United States
    Prog Neuropsychopharmacol Biol Psychiatry 32:1778-81. 2008
  7. doi request reprint Biperiden enhances L-DOPA methyl ester and dopamine D(l) receptor agonist SKF-82958 but antagonizes D(2)/D(3) receptor agonist rotigotine antihemiparkinsonian actions
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 49109 0632, United States
    Eur J Pharmacol 599:81-5. 2008
  8. doi request reprint Positron emission tomographic measure of brain dopamine dependence to nicotine as a model of drugs of abuse
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Psychopharmacology (Berl) 204:149-53. 2009
  9. doi request reprint Nicotine sensitization of monkey striatal dopamine release
    Edward F Domino
    Central Research Laboratory, Hamamatsu Photonics K K, Hamamatsu, Shizuoka 484 6601, Japan
    Eur J Pharmacol 607:91-5. 2009
  10. pmc Tobacco smoking produces widespread dominant brain wave alpha frequency increases
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Int J Psychophysiol 74:192-8. 2009

Research Grants

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Changes in craving for a cigarette and arterial nicotine plasma concentrations in abstinent smokers
    Sally K Guthrie
    College of Pharmacy, University of Michigan, Ann Arbor 48109 1065, USA
    Prog Neuropsychopharmacol Biol Psychiatry 28:617-23. 2004
    ..Both the psychology and pharmacology of nicotine/tobacco smoking are involved in craving reduction...
  2. pmc Denicotinized versus average nicotine tobacco cigarette smoking differentially releases striatal dopamine
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 5632, USA
    Nicotine Tob Res 15:11-21. 2013
    ..This study examined venous plasma concentrations effects of nicotine in cigarette smoking after overnight abstinence to release striatal dopamine (DA)...
  3. pmc Phencyclidine/schizophrenia: one view toward the past, the other to the future
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 5632, USA
    Schizophr Bull 38:914-9. 2012
    ..Research with this agent and its chemical derivatives like ketamine have provided a solid foundation for just a beginning to understanding the neuropathology of schizophrenia...
  4. doi request reprint Tobacco smoking produces greater striatal dopamine release in G-allele carriers with mu opioid receptor A118G polymorphism
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 5632, USA
    Prog Neuropsychopharmacol Biol Psychiatry 38:236-40. 2012
    ..To determine if carriers of the allelic expression of the G variant of the human mu opioid receptor (OPRM1) A118G polymorphism have greater increases in striatal dopamine (DA) release after tobacco smoking...
  5. ncbi request reprint Effects of nicotine on regional cerebral glucose metabolism in awake resting tobacco smokers
    E F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Neuroscience 101:277-82. 2000
    ..However, not all brain regions affected by nicotine are known to have many nicotinic cholinoceptors. The results are discussed in relation to the cognitive effects of nicotine...
  6. pmc Tobacco smoking and MRI/MRS brain abnormalities compared to nonsmokers
    E F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, United States
    Prog Neuropsychopharmacol Biol Psychiatry 32:1778-81. 2008
    ..A crucial question is whether these anatomical/chemical changes reverse toward normal when smokers quit. This review is presented to stimulate further research to answer this question...
  7. doi request reprint Biperiden enhances L-DOPA methyl ester and dopamine D(l) receptor agonist SKF-82958 but antagonizes D(2)/D(3) receptor agonist rotigotine antihemiparkinsonian actions
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 49109 0632, United States
    Eur J Pharmacol 599:81-5. 2008
    ..Biperiden interactions with L-DOPA methyl ester were more predominantly D(l) than D(2)/D(3) receptor-like in this animal model of hemiparkinsonism...
  8. doi request reprint Positron emission tomographic measure of brain dopamine dependence to nicotine as a model of drugs of abuse
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Psychopharmacology (Berl) 204:149-53. 2009
    ..A quantitative measure of the regional brain utilization of these catecholamines (CA) during nicotine dependence and withdrawal is important...
  9. doi request reprint Nicotine sensitization of monkey striatal dopamine release
    Edward F Domino
    Central Research Laboratory, Hamamatsu Photonics K K, Hamamatsu, Shizuoka 484 6601, Japan
    Eur J Pharmacol 607:91-5. 2009
    ..These data regarding the striatum are consistent with previous findings in rodents of nicotine sensitization of dopamine release especially in nucleus accumbens following repeated administration...
  10. pmc Tobacco smoking produces widespread dominant brain wave alpha frequency increases
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Int J Psychophysiol 74:192-8. 2009
    ..This study demonstrates that tobacco smoking produces widespread bilateral neocortical increases in dominant alpha EEG frequencies consistent with the stimulant effects of nicotine on the brainstem reticular activating system...
  11. doi request reprint Taming the ketamine tiger. 1965
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, Michigan 48109 5632, USA
    Anesthesiology 113:678-84. 2010
    ..The drug deserves further pharmacologic and clinical trials. It is proposed that the words "dissociative anesthetic" be used to describe the mental state produced by this drug...
  12. ncbi request reprint N-methyl-D-aspartate antagonists as drug models of schizophrenia: a surprising link to tobacco smoking
    Edward F Domino
    Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, USA
    Prog Neuropsychopharmacol Biol Psychiatry 28:801-11. 2004
    ..Tobacco-smoking schizophrenic patients transiently normalize prepulse inhibition. Nicotine appears to be one factor that may help explain some of these phenomena...
  13. ncbi request reprint Regional cerebral blood flow and plasma nicotine after smoking tobacco cigarettes
    Edward F Domino
    Department of Pharmacology, University of Michigan, Box 0632, Ann Arbor, MI 48109 0632, USA
    Prog Neuropsychopharmacol Biol Psychiatry 28:319-27. 2004
    ..Nicotine delivery by tobacco smoking is only one of the factors, which contribute to changes in rCBF...
  14. ncbi request reprint Clinical phenotyping strategies in selection of tobacco smokers for future genotyping studies
    Edward F Domino
    Department of Pharmacology, University of Michigan Ann Arbor, MI 48109 0632, USA
    Prog Neuropsychopharmacol Biol Psychiatry 26:1071-8. 2002
    ..1+/-10.9 mm Hg. There were no statistically significant gender differences. Persons who were outliers on any measure are potential candidates for future genotyping studies. Preliminary guidelines of what is needed are described...
  15. ncbi request reprint Effects of tobacco smoking on electroencephalographic, auditory evoked and event related potentials
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Brain Cogn 53:66-74. 2003
    ..These findings indicate that compared to nonsmokers smokers have a higher arousal level after smoking than when partially abstinent. Evidence for both normalization from tobacco abstinence as well as stimulation was obtained...
  16. ncbi request reprint Nicotine induced behavioral locomotor sensitization
    E F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, 48109 0632, USA
    Prog Neuropsychopharmacol Biol Psychiatry 25:59-71. 2001
    ..32 mg/kg. There was no cross-tolerance to 32 mg/kg of caffeine citrate in previously sensitized animals tolerant to the stimulant effects of nicotine...
  17. ncbi request reprint Effects of (+/-)-idazoxan alone and in combination with L-DOPA methyl ester in MPTP-induced hemiparkinsonian monkeys
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, Michigan 48109 0632, USA
    Receptors Channels 9:335-8. 2003
    ..05). The data support a role for alpha2-adrenergic receptor mechanisms in modulating the effects of L-DOPA on nigrostriatal dopamine function in the MPTP monkey model of hemiparkinsonism...
  18. ncbi request reprint Nicotine and tobacco dependence: normalization or stimulation?
    E F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Alcohol 24:83-6. 2001
    ..Results of other studies of acute smoking effects in smokers show an increase in dominant alpha rhythm greater than that of nonsmokers. This is evidence that tobacco smoking produces stimulation of brain activity in smokers...
  19. ncbi request reprint Comparative American and Japanese tobacco smoke uptake parameters after overnight tobacco deprivation
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Prog Neuropsychopharmacol Biol Psychiatry 27:973-84. 2003
    ..It is concluded that Japanese males inhale cigarettes in moderation compared to Americans. The results are discussed in relation to known ethnic, social, and genetic differences in CYP2A6 gene polymorphism...
  20. ncbi request reprint Chronic NMDA antagonism impairs working memory, decreases extracellular dopamine, and increases D1 receptor binding in prefrontal cortex of conscious monkeys
    Hideo Tsukada
    Central Research Laboratory, Hamamatsu Photonics K K, Shizuoka, Japan
    Neuropsychopharmacology 30:1861-9. 2005
    ..Furthermore, in response to lowered levels of DA in PFC, D(1)R binding is increased, whereas D(2)R binding is not...
  21. ncbi request reprint Nicotine normalizes increased prefrontal cortical dopamine D1 receptor binding and decreased working memory performance produced by repeated pretreatment with MK-801: a PET study in conscious monkeys
    Hideo Tsukada
    Central Research Laboratory, Hamamatsu Photonics KK, Hamakita, Shizuoka, Japan
    Neuropsychopharmacology 30:2144-53. 2005
    ..Working memory performance, impaired after chronic MK-801, was partially improved by acute nicotine. These results demonstrate that acute nicotine normalizes MK-801-induced PFC abnormality of D(1)R in PFC...
  22. ncbi request reprint Smoking modulation of mu-opioid and dopamine D2 receptor-mediated neurotransmission in humans
    David J Scott
    Department of Psychiatry, Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109 0720, USA
    Neuropsychopharmacology 32:450-7. 2007
    ....
  23. ncbi request reprint Regional cerebral blood flow responses to smoking in tobacco smokers after overnight abstinence
    Jon Kar Zubieta
    Department of Psychiatry, Mental Health Research Institute, 205 Zina Pitcher Pl, University of Michigan, Ann Arbor, MI 48109 0720, USA
    Am J Psychiatry 162:567-77. 2005
    ..The purpose of the study was to determine the effects of cigarette smoking on brain regional function in a group of chronic smokers by using cerebral blood flow (CBF) measures and positron emission tomography (PET)...
  24. ncbi request reprint Comparative effects of tobacco smoking and nasal nicotine
    Christian J Teter
    College of Pharmacy, Substance Abuse Research Center, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Eur J Clin Pharmacol 58:309-14. 2002
    ..Compare the electroencephalographic (EEG) and cardiovascular effects of tobacco smoking and nasal nicotine in the same subjects...
  25. ncbi request reprint Comparative effects of methamphetamine and nicotine on the striatal [(11)C]raclopride binding in unanesthetized monkeys
    Hideo Tsukada
    Central Research Laboratory, Hamamatsu Photonics K K, 5000 Hirakuchi, Hamakita, Shizuoka 434 8601, Japan
    Synapse 45:207-12. 2002
    ....
  26. doi request reprint Increased in vivo [11C]raclopride binding to brain dopamine receptors in amphetamine-treated rats
    Michael R Kilbourn
    Department of Radiology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    Eur J Pharmacol 654:254-7. 2011
    ..These results support increased baseline in vivo dopamine D(2) receptor antagonist radioligand binding after repeated amphetamine administration in rats...
  27. ncbi request reprint Conflicting evidence for the dopamine release theory of nicotine/tobacco dependence
    Edward F Domino
    Department of Pharmacology, University of Michigan, USA
    Nihon Shinkei Seishin Yakurigaku Zasshi 22:181-4. 2002
    ..The data for a primary role of nicotine release of brain dopamine are unimpressive compared to that of amphetamines and cocaine in conscious unanesthetized primates, both subhuman and human...
  28. ncbi request reprint Tobacco smoking increases gating of irrelevant and enhances attention to relevant tones
    Edward F Domino
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 0632, USA
    Nicotine Tob Res 4:71-8. 2002
    ..The data support the hypothesis that tobacco smoking enhances the "protective shield" or "stimulus barrier" to irrelevant and increases attention to relevant auditory stimuli...
  29. pmc Venous plasma nicotine correlates of hormonal effects of tobacco smoking
    Yue Xue
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 5632, USA
    Pharmacol Biochem Behav 95:209-15. 2010
    ..Increases in maximal plasma beta-endorphin levels following tobacco smoking were barely statistically significant with insufficient data to obtain a correlation coefficient...
  30. pmc Tobacco/nicotine and endogenous brain opioids
    Yue Xue
    Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109 5632, USA
    Prog Neuropsychopharmacol Biol Psychiatry 32:1131-8. 2008
    ..The present review examines the limited contribution of the endogenous opioid system to the complex effects of nicotine/tobacco smoking...
  31. ncbi request reprint Acute effects of cigarette smoking on global cerebral blood flow in overnight abstinent tobacco smokers
    Takao Shinohara
    Department of Neurology, Research Institute for Brain and Blood Vessels, Akita, Japan
    Nicotine Tob Res 8:113-21. 2006
    ..These individual differences result in important bimodal effects of smoking on the brains of different young adult tobacco smokers...
  32. ncbi request reprint Estimation of D2-like receptor occupancy by dopamine in the putamen of hemiparkinsonian Monkeys
    Svetlana I Chefer
    Neuroimaging Research Branch, Intramural Research Program, National Institute on Drug Abuse, NIH DHHS, Baltimore, MD, USA
    Neuropsychopharmacology 33:270-8. 2008
    ....

Research Grants8

  1. NICOTINE EFFECTS ON CEREBRAL BLOOD FLOW AND METABOLISM
    EDWARD DOMINO; Fiscal Year: 2001
    ..This could set the stage for the study of nicotine effects in persons with cofactors for smoking, such as attention deficit disorder or mood disorders. ..
  2. Effects of Nicotine on Human Cerebral Transmitters
    EDWARD DOMINO; Fiscal Year: 2007
    ..This research will provide direct proof of basic neuroscience studies, which indicate nicotine releases neurotransmitters such as dopamine and endogenous opioids. ..