Samuel R Dominguez

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Pediatric neurological complications of 2009 pandemic influenza A (H1N1)
    Sita Kedia
    Department of Child Neurology, The Children s Hospital, University of Colorado School of Medicine, Aurora, USA
    Arch Neurol 68:455-62. 2011
  2. pmc Human coronavirus HKU1 infection of primary human type II alveolar epithelial cells: cytopathic effects and innate immune response
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, United States of America
    PLoS ONE 8:e70129. 2013
  3. pmc Genomic analysis of 16 Colorado human NL63 coronaviruses identifies a new genotype, high sequence diversity in the N-terminal domain of the spike gene and evidence of recombination
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 E 19th Ave, Room P18 9403B, Aurora, CO 80045, USA
    J Gen Virol 93:2387-98. 2012
  4. doi request reprint Advances in the treatment of Kawasaki disease
    Samuel R Dominguez
    Department of Pediatrics, Section of Infectious Diseases, Children s Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Curr Opin Pediatr 25:103-9. 2013
  5. pmc Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Med Virol 81:1597-604. 2009
  6. pmc Rhino/enteroviruses in hospitalized children: a comparison to influenza viruses
    Kevin Messacar
    Children s Hospital Colorado, Section of Infectious Diseases, Aurora, CO 80045, United States
    J Clin Virol 56:41-5. 2013
  7. ncbi request reprint Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Health Science Center, Denver, CO, USA
    J Infect Dis 194:1697-701. 2006
  8. pmc Multiplex MassTag-PCR for respiratory pathogens in pediatric nasopharyngeal washes negative by conventional diagnostic testing shows a high prevalence of viruses belonging to a newly recognized rhinovirus clade
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, CO, USA
    J Clin Virol 43:219-22. 2008
  9. pmc Isolation, propagation, genome analysis and epidemiology of HKU1 betacoronaviruses
    Samuel R Dominguez
    Departments of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 E 19th Ave, Room P18 9403B, Aurora, CO 80045, USA
    J Gen Virol 95:836-48. 2014
  10. pmc Detection of group 1 coronaviruses in bats in North America
    Samuel R Dominguez
    University of Colorado Health Sciences Center, Aurora, Colorado 80045, USA
    Emerg Infect Dis 13:1295-300. 2007

Collaborators

Detail Information

Publications21

  1. pmc Pediatric neurological complications of 2009 pandemic influenza A (H1N1)
    Sita Kedia
    Department of Child Neurology, The Children s Hospital, University of Colorado School of Medicine, Aurora, USA
    Arch Neurol 68:455-62. 2011
    ..To analyze the spectrum of neurological manifestations in children hospitalized with pandemic influenza A H1N1 virus of 2009 (pH1N1)...
  2. pmc Human coronavirus HKU1 infection of primary human type II alveolar epithelial cells: cytopathic effects and innate immune response
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, United States of America
    PLoS ONE 8:e70129. 2013
    ..Furthermore, these studies demonstrate that human alveolar cells can be used to isolate and study novel human respiratory viruses that cause lower respiratory tract disease. ..
  3. pmc Genomic analysis of 16 Colorado human NL63 coronaviruses identifies a new genotype, high sequence diversity in the N-terminal domain of the spike gene and evidence of recombination
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 E 19th Ave, Room P18 9403B, Aurora, CO 80045, USA
    J Gen Virol 93:2387-98. 2012
    ..Ten different amino acid sequences were found in the NTD of the spike protein among these NL63 strains and the 75 partial published sequences of NTDs from strains found at different times throughout the world...
  4. doi request reprint Advances in the treatment of Kawasaki disease
    Samuel R Dominguez
    Department of Pediatrics, Section of Infectious Diseases, Children s Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Curr Opin Pediatr 25:103-9. 2013
    ..Although there is no conclusive body of evidence defining the best second and third-line therapies for Kawasaki patients, there have been several recent studies published describing the results of these therapies...
  5. pmc Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Med Virol 81:1597-604. 2009
    ..Our data raise the possibility that HCoV may play a role in gastrointestinal and CNS disease. Additional studies are needed to investigate the potential roles of HCoVs in these diseases...
  6. pmc Rhino/enteroviruses in hospitalized children: a comparison to influenza viruses
    Kevin Messacar
    Children s Hospital Colorado, Section of Infectious Diseases, Aurora, CO 80045, United States
    J Clin Virol 56:41-5. 2013
    ..The relative impact of human rhino/enteroviruses (HRV/EV) compared to influenza viruses on hospitalized children is unknown...
  7. ncbi request reprint Blinded case-control study of the relationship between human coronavirus NL63 and Kawasaki syndrome
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Health Science Center, Denver, CO, USA
    J Infect Dis 194:1697-701. 2006
    ..These data suggest that, although HCoV-NL63 was circulating in children in our community during the time of the study, the prevalence of infection with HCoV-NL63 was not greater in patients with KS than in control subjects...
  8. pmc Multiplex MassTag-PCR for respiratory pathogens in pediatric nasopharyngeal washes negative by conventional diagnostic testing shows a high prevalence of viruses belonging to a newly recognized rhinovirus clade
    Samuel R Dominguez
    Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, CO, USA
    J Clin Virol 43:219-22. 2008
    ..Respiratory infections are the most common infectious diseases in humans worldwide and are a leading cause of death in children less than 5 years of age...
  9. pmc Isolation, propagation, genome analysis and epidemiology of HKU1 betacoronaviruses
    Samuel R Dominguez
    Departments of Pediatrics, University of Colorado School of Medicine, Anschutz Medical Campus, 12800 E 19th Ave, Room P18 9403B, Aurora, CO 80045, USA
    J Gen Virol 95:836-48. 2014
    ..Elucidating the function of and mechanisms responsible for the formation of these varying tandem repeats will increase our understanding of the replication process and pathogenicity of HKU1 and potentially of other coronaviruses. ..
  10. pmc Detection of group 1 coronaviruses in bats in North America
    Samuel R Dominguez
    University of Colorado Health Sciences Center, Aurora, Colorado 80045, USA
    Emerg Infect Dis 13:1295-300. 2007
    ..Because of the potential for bat coronaviruses to cause disease in humans and animals, further surveillance and characterization of bat coronaviruses in North America are needed...
  11. pmc Alphacoronaviruses in New World bats: prevalence, persistence, phylogeny, and potential for interaction with humans
    Christina Osborne
    Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 6:e19156. 2011
    ..Further CoV surveillance studies in bats throughout the Americas are warranted...
  12. pmc Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formation
    Zhaohui Qian
    Department of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    PLoS ONE 8:e76469. 2013
    ....
  13. doi request reprint Kawasaki disease in a pediatric intensive care unit: a case-control study
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado Denver School of Medicine, Denver, Colorado, USA
    Pediatrics 122:e786-90. 2008
    ..We conducted a case-control study to ascertain the clinical presentations, risk factors, and clinical outcomes of children who had Kawasaki disease and were admitted to the ICU of our children's hospital...
  14. doi request reprint Kawasaki disease and the pediatric gastroenterologist: a diagnostic challenge
    Mohammed Eladawy
    Ain Shams University Department of Pediatrics, University of Colorado School of Medicine and Children s Hospital, Aurora, CO 80045, USA
    J Pediatr Gastroenterol Nutr 56:297-9. 2013
    ..In the present study, we report a series of patients with KD in whom a gastroenterology consult was obtained before consideration of the diagnosis of KD...
  15. doi request reprint Preventing coronary artery abnormalities: a need for earlier diagnosis and treatment of Kawasaki disease
    Samuel R Dominguez
    Department of Pediatrics, University of Colorado School of Medicine and Children s Hospital Colorado, Aurora, CO 80045
    Pediatr Infect Dis J 31:1217-20. 2012
    ..The aim of this study was to explore the timing of coronary artery (CA) abnormalities in light of the expanding clinical spectrum of Kawasaki disease (KD)...
  16. pmc Hospitalized children with 2009 pandemic influenza A (H1N1): comparison to seasonal influenza and risk factors for admission to the ICU
    Dayanand Bagdure
    Department of Pediatric Critical Care, The Children s Hospital, University of Colorado School of Medicine, Aurora, Colorado, United States of America
    PLoS ONE 5:e15173. 2010
    ..Limited data are available describing the clinical presentation and risk factors for admission to the intensive care unit for children with 2009 H1N1 infection...
  17. doi request reprint A cluster of acute flaccid paralysis and cranial nerve dysfunction temporally associated with an outbreak of enterovirus D68 in children in Colorado, USA
    Kevin Messacar
    Departments of Pediatric Infectious Diseases, Children s Hospital Colorado and University of Colorado School of Medicine, Aurora, CO, USA Hospital Medicine, Children s Hospital Colorado and University of Colorado School of Medicine, Aurora, CO, USA
    Lancet 385:1662-71. 2015
    ..We aimed to assess a cluster of children with acute flaccid paralysis and cranial nerve dysfunction geographically and temporally associated with an outbreak of enterovirus-D68 respiratory disease...
  18. doi request reprint Epidemiology and clinical characteristics of infants with human parechovirus or human herpes virus-6 detected in cerebrospinal fluid tested for enterovirus or herpes simplex virus
    Kevin Messacar
    Department of Pediatrics, Section of Hospital Medicine and Infectious Diseases, Aurora, Colorado Department of Pathology and Laboratory Medicine, Aurora, Colorado
    J Med Virol 87:829-35. 2015
    ..The clinical and fiscal impact of testing infants for HPeV and HHV-6 needs to be determined...
  19. pmc The new age of virus discovery: genomic analysis of a novel human betacoronavirus isolated from a fatal case of pneumonia
    Kathryn V Holmes
    Department of Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA
    MBio 4:e00548-12. 2013
    ....
  20. doi request reprint Viral gastroenteritis in children in Colorado 2006-2009
    Christina M Osborne
    University of Colorado School of Medicine, Aurora, Colorado, 80045
    J Med Virol 87:931-9. 2015
    ..This data support the superiority of RT-PCR compared to EM for diagnosis of viral gastroenteritis. J. Med. Virol. 87:931-939, 2015. © 2015 Wiley Periodicals, Inc. ..