Research Topics
| Zora DjuricSummaryAffiliation: University of Michigan Country: USA Publications
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Publications
A Mediterranean dietary intervention in persons at high risk of colon cancer: recruitment and retention to an intensive study requiring biopsiesZora Djuric
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109, USA
Contemp Clin Trials 33:881-8. 2012..These findings suggest that flexible sigmoidoscopy does not appear to be a barrier for recruitment of high-risk individuals to an intensive dietary intervention trial, but that completing food records can be...
Lifestyle factors associated with serum N-3 fatty acid levels in breast cancer patientsZora Djuric
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109, USA
Breast 21:608-11. 2012..Counseling for prevention of weight gain also tended to increase n3 fatty acid blood levels over time during chemotherapy...
Association of dietary quercetin with reduced risk of proximal colon cancerZora Djuric
Department of Family Medicine and Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA
Nutr Cancer 64:351-60. 2012..99). These results suggest that quercetin can have disparate effects on colon cancer risk depending on whether dietary intakes of fruit or tea are high, and that quercetin had protective effects only on proximal, not distal, colon cancer...
The Mediterranean diet: effects on proteins that mediate fatty acid metabolism in the colonZora Djuric
Department of Family Medicine, University of Michigan, Ann Arbor, Michigan 48109 5930, USA
Nutr Rev 69:730-44. 2011..The proteins involved in these pathways are ripe for investigation using proteomic approaches and may be targets for colon cancer prevention...
A Mediterranean dietary intervention in healthy American women changes plasma carotenoids and fatty acids in distinct clustersZora Djuric
Department of Family Medicine, University of Michigan, Cancer and Geriatrics Center, Ann Arbor, MI 48109 5930, USA
Nutr Res 29:156-63. 2009..The changes in blood levels indicate the exchange list diet was effective for targeting Mediterranean nutrient intakes using foods available in the United States...
Influence of lactation history on breast nipple aspirate fluid yields and fluid compositionZora Djuric
Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48109 0930, USA
Breast J 11:92-9. 2005..The results of this study provide further evidence of the potential benefits of prolonged lactation via its influence on NAF composition...
Effects of high fruit-vegetable and/or low-fat intervention on plasma micronutrient levelsZora Djuric
Deapartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109 0930, USA
J Am Coll Nutr 25:178-87. 2006..The objective of this study was to determine the relative effects of reduced fat and/or increased fruit-vegetable (FV) intakes on plasma micronutrient levels...
Relationships of psychosocial factors to dietary intakes of preadolescent girls from diverse backgroundsZora Djuric
Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, USA
Matern Child Nutr 2:79-90. 2006..This was a small study, but the data suggest that simple comparisons between ethnic groups may not adequately capture the complexity of family and psychosocial factors contributing to good dietary practices...
Effects of high fruit-vegetable and/or low-fat intervention on breast nipple aspirate fluid micronutrient levelsZora Djuric
Department of Family Medicine, University of Michigan, Room 2150 Cancer and Geriatrics Center, Ann Arbor, MI 48109 0930, USA
Cancer Epidemiol Biomarkers Prev 16:1393-9. 2007..A change in diet is known to affect micronutrient levels in blood but to what extent diet can affect micronutrient levels in the breast is not yet well established...
A randomized feasibility trial of brief telephone counseling to increase fruit and vegetable intakesZora Djuric
University of Michigan, Department of Family Medicine, Ann Arbor, MI 48109, USA
Prev Med 50:265-71. 2010..This study examined the feasibility of eliciting dietary changes in subjects recruited from a diverse primary care setting in Michigan using a written, one-page plan, either alone or with telephone counseling...
Obesity is associated with atypia in breast ductal lavage of women with proliferative breast diseaseZora Djuric
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109, United States
Cancer Epidemiol 33:242-8. 2009..Benign proliferative breast disease without atypia slightly increases breast cancer risk but there are currently few clinical options for breast cancer prevention in this group of women...
A pilot trial of spirituality counseling for weight loss maintenance in African American breast cancer survivorsZora Djuric
Department of Family Medicine, University of Michigan, Ann Arbor, Michigan 48109 5930, USA
J Natl Med Assoc 101:552-64. 2009..The spirituality counseling framework therefore may be further refined and useful for other health promotion studies with African American populations...
Design of a Mediterranean exchange list diet implemented by telephone counselingZora Djuric
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109 5930, USA
J Am Diet Assoc 108:2059-65. 2008..0 to 8.6 servings/day (P < 0.05)...
Effects of low-fat and/or high-fruit-and-vegetable diets on plasma levels of 8-isoprostane-F2alpha in the Nutrition and Breast Health studyGang Chen
Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, USA
Nutr Cancer 50:155-60. 2004..These results indicate that low-fat diets or high-FV diets are unlikely to affect plasma levels of 8-isoprostane-F2a in healthy,premenopausal women who do not lose weight during dietary change...
Methods to increase fruit and vegetable intake with and without a decrease in fat intake: compliance and effects on body weight in the nutrition and breast health studyZora Djuric
Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, USA
Nutr Cancer 43:141-51. 2002..Maintenance of energy intake, therefore, did not appear to be attained intrinsically when individuals were counseled to make changes in the composition of their diets...
Women participating in a dietary intervention trial maintain dietary changes without much effect on household membersKatherine Radakovich
Barbara Ann Karmanos Cancer Institute and Nutrition Department, Wayne State University, Detroit, MI 48201, USA
Nutr Cancer 55:44-52. 2006....
Plasma carotenoids, tocopherols, and antioxidant capacity in a 12-week intervention study to reduce fat and/or energy intakesZora Djuric
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA
Nutrition 19:244-9. 2003..Dietary fat and energy may affect intake and bioavailability of carotenoids and tocopherols, and these micronutrient levels in turn can contribute to the antioxidant capacity of plasma...
Combining weight-loss counseling with the weight watchers plan for obese breast cancer survivorsZora Djuric
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA
Obes Res 10:657-65. 2002..The objective was to develop effective weight-loss methods for women who have had breast cancer, because obesity may result in an adverse prognosis...
Nutritional predictors for cellular nipple aspirate fluid: Nutrition and Breast Health StudyIkuko Kato
Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI, USA
Breast Cancer Res Treat 97:33-9. 2006..17 (95% CI 0.04-0.65) and 0.19 (95% CI 0.04-0.91), respectively. These results are generally in support of roles of nutritional factors in breast cancer and thus further studies are warranted...
Effect of cyclooxygenase genotype and dietary fish oil on colonic eicosanoids in miceAndrew P Neilson
Department of Family Medicine, University of Michigan Medical School, University of Michigan, Ann Arbor, MI 48109, USA
J Nutr Biochem 23:966-76. 2012..These results indicate that in normal colon, inhibition of COX-2 would have little effect on reducing PGE(2) levels...
Improvement of metabolism among obese breast cancer survivors in differing weight loss regimensK L Catherine Jen
Department of Nutrition and Food Science, Wayne State University, Detroit, Michigan 48202, USA
Obes Res 12:306-12. 2004..To compare the efficacy of different weight loss regimens on body weight loss and metabolic improvement in breast cancer survivors...
Phase II study of the effects of ginger root extract on eicosanoids in colon mucosa in people at normal risk for colorectal cancerSuzanna M Zick
Department of Family Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
Cancer Prev Res (Phila) 4:1929-37. 2011..Ginger also seemed to be tolerable and safe. Further investigation in people at high risk for CRC seems warranted...
Relationship of psychiatric diagnosis and weight loss maintenance in obese breast cancer survivorsIsabella Jenkins
Department of Psychiatry, Wayne State University, Detroit, Michigan, USA
Obes Res 11:1369-75. 2003....
Soy isoflavones in the treatment of prostate cancerMaha Hussain
Division of Hematology and Oncology, Wayne State University, Detroit, MI 48201, USA
Nutr Cancer 47:111-7. 2003..00002) and from 0.11 to 0.51 microM (P = 0.00001), respectively. No significant changes were observed in serum levels of testosterone, IGF-1, IGFBP-3, or 5-OHmdU. These data suggest that soy isoflavones may benefit some patients with Pca...
Quality of life as a predictor of weight loss in obese, early-stage breast cancer survivorsLinda L Darga
Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA
Oncol Nurs Forum 34:86-92. 2007..To investigate whether quality of life (QOL) assessed before weight loss intervention predicts weight loss and, in turn, what the effect of weight loss is on QOL measures after 12 months in early-stage breast cancer survivors...
Non-steroidal anti-inflammatory drug (NSAID) use and levels of a lipid oxidation marker in plasma and nipple aspirate fluidsIkuko Kato
Karmanos Cancer Institute, Detroit, MI 48201, USA
Breast Cancer Res Treat 97:145-8. 2006..These results indicate that NSAID use can result in lower levels of 15-F(2t)-isoprostane, which may have implications for the effects of NSAID use on breast cancer risk...
Levels of fat-soluble micronutrients and 2,6-cyclolycopene-1,5-diol in head and neck cancer patientsZora Djuric
Department of Family Medicine, University of Michigan, Ann Arbor, MI 48109, USA
Int J Vitam Nutr Res 77:382-8. 2007..Although this was a pilot investigation, there was no evidence that 2,6-cyclolycopene-1,5-diol A formation was appreciably affected by smoking status, but alpha-tocopherol levels were higher in smokers...
Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from women participating in an intervention trial of low-fat and low-energy dietsZora Djuric
Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA
Biomarkers 9:93-101. 2004..The women participating in this study were not selected on the basis of increased cancer risk; therefore, they may have had low baseline levels of damage that were not amenable to further reduction by dietary change...
Effect of fish oil on levels of R- and S-enantiomers of 5-, 12-, and 15-hydroxyeicosatetraenoic acids in mouse colonic mucosaAndrew P Neilson
Department of Family Medicine, University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan 48197, USA
Nutr Cancer 64:163-72. 2012..There was apparent shunting of arachidonic acid to 12-/15-LOX in the COX-1 null animals. This is the first report of the enantiomeric composition of HETEs in the colon in vivo and shows large effects of fish oil in the normal colon...
Baseline leptin levels predict change in leptin levels during weight loss in obese breast cancer survivorsAnanda Sen
Department of Family Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
Breast J 13:180-6. 2007..Breast cancer survivors with initially higher leptin levels may differ with regard to regulation of change in leptin during weight loss resulting in relatively smaller changes in leptin with equivalent amounts of weight loss...
Effect of low-fat and/or low-energy diets on anthropometric measures in participants of the women's diet studyZora Djuric
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA
J Am Coll Nutr 21:38-46. 2002..To compare the effects of low-fat, low-energy and combination low-fat/low-energy intervention on changes in six anthropometric measures in Caucasian and African-American free-living women...
Pharmacokinetics of curcumin conjugate metabolites in healthy human subjectsShaiju K Vareed
Department of Internal Medicine, University of Michigan Medical School and Veterans Affairs Medical Center, Ann Arbor, Michigan, USA
Cancer Epidemiol Biomarkers Prev 17:1411-7. 2008..Curcumin is a polyphenol, found in the spice turmeric, that has promising anticancer properties, but previous studies suggest that absorption of curcumin may be limited...
Detection of 2,6-cyclolycopene-1,5-diol in breast nipple aspirate fluids and plasma: a potential marker of oxidative stressGang Chen
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA
Cancer Epidemiol Biomarkers Prev 11:1592-6. 2002..The high levels of 2,6-cyclolycopene-1,5-diol and 8-isoprostane in NAF are consistent with high levels of oxidative stress in the breast...
Intra- and inter-individual variability in measurements of biomarkers for oxidative damage in vivo: Nutrition and Breast Health StudyI Kato
Barbara Ann Karmanos Cancer Institute and Wayne State University School of Medicine, Detroit, MI 48201, USA
Biomarkers 11:143-52. 2006..There also may be ample room to optimize laboratory techniques to quantify markers of oxidative DNA damage...
Plasma levels of resistin-like molecule beta in humansAndrew P Neilson
Comprehensive Cancer Center University of Michigan, Ann Arbor, MI, USA
Cancer Epidemiol 35:485-9. 2011..In the present study, we evaluated whether RELMβ could be measured in human plasma and the influence of selected host and behavioral factors on RELMβ levels, including known risk factors for colorectal cancer...
Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjectsSuzanna M Zick
Deoartment of Family Medicine, University of Michigan Medical School, Ann Arbor, MI 48104, USA
Cancer Epidemiol Biomarkers Prev 17:1930-6. 2008..We conducted a clinical trial with 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol, examining the pharmacokinetics and tolerability of these analytes and their conjugate metabolites...
Effects of lycopene supplementation in patients with localized prostate cancerOmer Kucuk
Division of Hematology and Oncology, 3990 John R, Barbara Ann Karmanos Cancer Institute, Wayne State University, 5 Hudson, Detroit, MI 48201, USA
Exp Biol Med (Maywood) 227:881-5. 2002..This pilot study suggests that lycopene may have beneficial effects in prostate cancer. Larger clinical trials are warranted to investigate the potential preventive and/or therapeutic role of lycopene in prostate cancer...
Ultra-low flow liquid chromatography assay with ultraviolet (UV) detection for piperine quantitation in human plasmaMadhuri Kakarala
Department of Internal Medicine, Division of Hematology Oncology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
J Agric Food Chem 58:6594-9. 2010..The method sensitivity equals that of liquid chromatography/tandem mass spectrometry (LC/MSMS) methods with much less cost...
Partial associations of dietary iron, smoking and intestinal bacteria with colorectal cancer riskIkuko Kato
a Karmanos Cancer Institute, and Department of Pathology, Wayne State University School of Medicine, Detroit, Michigan, USA
Nutr Cancer 65:169-77. 2013..2.23) (P = 0.014) and U.S. samples (6.65 vs. 4.37) (P < 0.001). Potential roles of iron from cigarette smoking and dietary heme in CRC through altering irontrophic luminal bacterial population may warrant further investigation...
The mothers, Omega-3 and mental health studyEllen Mozurkewich
University of Michigan, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Ann Arbor, Michigan, USA
BMC Pregnancy Childbirth 11:46. 2011....
Effect of varying caloric restriction levels on female rat growth and 5-hydroxymethyl-2'-deoxyuridine in DNAZora Djuric
Barbara Ann Karmanos Cancer Institute, Wayne State University, 100 E Warren, Detroit, Michigan 48118, USA
Toxicol Sci 66:125-30. 2002..This data raises the question of whether the previously reported effects of calorie restriction on preventing oxidative stress in mammary gland are dependent on the type of dietary formulation used...
Research Grants
- WEIGHT LOSS IN OBESE BREAST CANCER SURVIVORSZora Djuric; Fiscal Year: 2002..This study should be useful to determine certain psychosocial are associated with extent of weight loss, and in turn whether weight loss is associated with changes in selected markers of breast cancer risk. ..
- DIETARY INTERVENTION--WOMEN HIGH RISK FOR BREAST CANCERZora Djuric; Fiscal Year: 2002..The use of biomarkers will allow to evaluate the cancer-protective effects of dietary modulation over a relatively short period of time. ..
- A Mediterranean Diet in for Colon Cancer PreventionZora Djuric; Fiscal Year: 2010....
- A Mediterranean Diet in for Colon Cancer PreventionZora Djuric; Fiscal Year: 2009....
